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Items: 1 to 20 of 22

1.
DLC1 is a chromosome 8p tumor suppressor whose loss promotes hepatocellular carcinoma
Wen Xue, Alexander Krasnitz, Robert Lucito, Raffaella Sordella, Linda VanAelst, Carlos Cordon-Cardo, Stephan Singer, Florian Kuehnel, Michael Wigler, Scott Powers, Lars Zender, Scott W. Lowe
Genes Dev. 2008 Jun 1; 22(11): 1439–1444. doi: 10.1101/gad.1672608
PMCID:
PMC2418580
AbstractArticlePDF–467K
2.
Inactivation of the Dlc1 gene cooperates with down-regulation of p15INK4b and p16Ink4a leading to neoplastic transformation and poor prognosis in human cancer
Xiaolan Qian, Marian E. Durkin, Dunrui Wang, Brajendra K. Tripathi, Lyra Olson, Xu-yu Yang, William C. Vass, Nicholas C. Popescu, Douglas R. Lowy
Cancer Res. Author manuscript; available in PMC 2020 Sep 8.
Published in final edited form as: Cancer Res. 2012 Nov 15; 72(22): 5900–5911. Published online 2012 Sep 25. doi: 10.1158/0008-5472.CAN-12-2368
PMCID:
PMC7477393
AbstractArticlePDF–2.3M
3.
Effects of DLC1 Deficiency on Endothelial Cell Contact Growth Inhibition and Angiosarcoma Progression
David Sánchez-Martín, Atsushi Otsuka, Kenji Kabashima, Taekyu Ha, Dunrui Wang, Xiaolan Qian, Douglas R Lowy, Giovanna Tosato
J Natl Cancer Inst. 2018 Apr; 110(4): 390–399. Published online 2017 Nov 30. doi: 10.1093/jnci/djx219
PMCID:
PMC6059196
AbstractArticlePDF–2.3M
4.
Down-regulation of DLC1 in endothelial cells compromises the angiogenesis process
Yi-Ping Shih, Sarah Y. Yuan, Su Hao Lo
Cancer Lett. Author manuscript; available in PMC 2018 Jul 10.
Published in final edited form as: Cancer Lett. 2017 Jul 10; 398: 46–51. Published online 2017 Apr 10. doi: 10.1016/j.canlet.2017.04.004
PMCID:
PMC5460982
AbstractArticlePDF–395K
5.
Regulation of white and brown adipocyte differentiation by RhoGAP DLC1
Choon Kiat Sim, Sun-Yee Kim, Reinhard Brunmeir, Qiongyi Zhang, Hongyu Li, Dharmini Dharmasegaran, Carol Leong, Ying Yan Lim, Weiping Han, Feng Xu
PLoS One. 2017; 12(3): e0174761. Published online 2017 Mar 30. doi: 10.1371/journal.pone.0174761
PMCID:
PMC5373604
AbstractArticlePDF–4.0M
6.
The Role of Dlc1 Isoform 2 in K-Ras2G12D Induced Thymic Cancer
Mohammad Golam Sabbir, Heather Prieditis, Esther Ravinsky, Michael R. A. Mowat
PLoS One. 2012; 7(7): e40302. Published online 2012 Jul 5. doi: 10.1371/journal.pone.0040302
PMCID:
PMC3390377
AbstractArticlePDF–4.0M
7.
Identification and characterization of Dlc1 isoforms in the mouse and study of the biological function of a single gene trapped isoform
Mohammad G Sabbir, Nichola Wigle, Shauna Loewen, Yuan Gu, Cordula Buse, Geoffrey G Hicks, Michael RA Mowat
BMC Biol. 2010; 8: 17. Published online 2010 Mar 3. doi: 10.1186/1741-7007-8-17
PMCID:
PMC2839985
AbstractArticlePDF–6.6M
8.
Mechanotransduction in talin through the interaction of the R8 domain with DLC1
Alexander William M. Haining, Rolle Rahikainen, Ernesto Cortes, Dariusz Lachowski, Alistair Rice, Magdalena von Essen, Vesa P. Hytönen, Armando del Río Hernández
PLoS Biol. 2018 Jul; 16(7): e2005599. Published online 2018 Jul 20. doi: 10.1371/journal.pbio.2005599
PMCID:
PMC6054372
AbstractArticlePDF–15M
9.
Tensin1 positively regulates RhoA activity through its interaction with DLC1
Yi-Ping Shih, Peng Sun, Aifeng Wang, Su Hao Lo
Biochim Biophys Acta. Author manuscript; available in PMC 2016 Dec 1.
Published in final edited form as: Biochim Biophys Acta. 2015 Dec; 1853(12): 3258–3265. Published online 2015 Sep 28. doi: 10.1016/j.bbamcr.2015.09.028
Correction in:
Biochim Biophys Acta. 2018 Jun 2
PMCID:
PMC4621260
AbstractArticlePDF–1.0M
10.
DLC1-dependent parathyroid hormone–like hormone inhibition suppresses breast cancer bone metastasis
Yufeng Wang, Rong Lei, Xueqian Zhuang, Ning Zhang, Hong Pan, Gang Li, Jing Hu, Xiaoqi Pan, Qian Tao, Da Fu, Jianru Xiao, Y. Eugene Chin, Yibin Kang, Qifeng Yang, Guohong Hu
J Clin Invest. 2014 Apr 1; 124(4): 1646–1659. Published online 2014 Mar 3. doi: 10.1172/JCI71812
PMCID:
PMC3973085
AbstractArticlePDF–5.2M
11.
Stepwise reprogramming of liver cells to a pancreas progenitor state by the transcriptional regulator Tgif2
Nuria Cerdá-Esteban, Heike Naumann, Silvia Ruzittu, Nancy Mah, Igor M. Pongrac, Corinna Cozzitorto, Angela Hommel, Miguel A. Andrade-Navarro, Ezio Bonifacio, Francesca M. Spagnoli
Nat Commun. 2017; 8: 14127. Published online 2017 Feb 13. doi: 10.1038/ncomms14127
PMCID:
PMC5316826
AbstractArticlePDF–2.7M
12.
Transgenerational epigenetic effects imposed by neonicotinoid thiacloprid exposure
Ouzna Dali, Shereen D’Cruz, Louis Legoff, Mariam Diba Lahmidi, Celine Heitz, Pierre-Etienne Merret, Pierre-Yves Kernanec, Farzad Pakdel, Fatima Smagulova
Life Sci Alliance. 2024 Feb; 7(2): e202302237. Published online 2023 Nov 16. doi: 10.26508/lsa.202302237
PMCID:
PMC10654101
AbstractArticlePDF–3.1M
13.
A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome
Jens Hansen, Thomas Floss, Petra Van Sloun, Ernst-Martin Füchtbauer, Franz Vauti, Hans-Hennig Arnold, Frank Schnütgen, Wolfgang Wurst, Harald von Melchner, Patricia Ruiz
Proc Natl Acad Sci U S A. 2003 Aug 19; 100(17): 9918–9922. Published online 2003 Aug 6. doi: 10.1073/pnas.1633296100
PMCID:
PMC187885
AbstractArticlePDF–287K
14.
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells
Doug Stryke, Michiko Kawamoto, Conrad C. Huang, Susan J. Johns, Leslie A. King, Courtney A. Harper, Elaine C. Meng, Roy E. Lee, Alice Yee, Larry L'Italien, Pao-Tien Chuang, Stephen G. Young, William C. Skarnes, Patricia C. Babbitt, Thomas E. Ferrin
Nucleic Acids Res. 2003 Jan 1; 31(1): 278–281. doi: 10.1093/nar/gkg064
PMCID:
PMC165511
AbstractArticlePDF–217K
15.
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells
Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin
Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108
PMCID:
PMC2556270
AbstractArticlePDF–493K
16.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
17.
Wnk1 kinase deficiency lowers blood pressure in mice: A gene-trap screen to identify potential targets for therapeutic intervention
Brian P. Zambrowicz, Alejandro Abuin, Ramiro Ramirez-Solis, Lizabeth J. Richter, James Piggott, Hector BeltrandelRio, Eric C. Buxton, Joel Edwards, Rick A. Finch, Carl J. Friddle, Anupma Gupta, Gwenn Hansen, Yi Hu, Wenhu Huang, Crystal Jaing, Billie Wayne Key, Jr., Peter Kipp, Buckley Kohlhauff, Zhi-Qing Ma, Diane Markesich, Robert Payne, David G. Potter, Ny Qian, Joseph Shaw, Jeff Schrick, Zheng-Zheng Shi, Mary Jean Sparks, Isaac Van Sligtenhorst, Peter Vogel, Wade Walke, Nianhua Xu, Qichao Zhu, Christophe Person, Arthur T. Sands
Proc Natl Acad Sci U S A. 2003 Nov 25; 100(24): 14109–14114. Published online 2003 Nov 10. doi: 10.1073/pnas.2336103100
Correction in:
Proc Natl Acad Sci U S A. 2004 Mar 23; 101(12): 4332.
PMCID:
PMC283554
AbstractArticlePDF–481K
18.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M
19.
RIKEN Integrated Sequence Analysis (RISA) System—384-Format Sequencing Pipeline with 384 Multicapillary Sequencer
Kazuhiro Shibata, Masayoshi Itoh, Katsunori Aizawa, Sumiharu Nagaoka, Nobuya Sasaki, Piero Carninci, Hideaki Konno, Junichi Akiyama, Katsuo Nishi, Tokuji Kitsunai, Hideo Tashiro, Mari Itoh, Noriko Sumi, Yoshiyuki Ishii, Shin Nakamura, Makoto Hazama, Tsutomu Nishine, Akira Harada, Rintaro Yamamoto, Hiroyuki Matsumoto, Sumito Sakaguchi, Takashi Ikegami, Katsuya Kashiwagi, Syuji Fujiwake, Kouji Inoue, Yoshiyuki Togawa, Masaki Izawa, Eiji Ohara, Masanori Watahiki, Yuko Yoneda, Tomokazu Ishikawa, Kaori Ozawa, Takumi Tanaka, Shuji Matsuura, Jun Kawai, Yasushi Okazaki, Masami Muramatsu, Yorinao Inoue, Akira Kira, Yoshihide Hayashizaki
Genome Res. 2000 Nov; 10(11): 1757–1771. doi: 10.1101/gr.152600
PMCID:
PMC310992
AbstractArticlePDF–3.4M
20.
Normalization and Subtraction of Cap-Trapper-Selected cDNAs to Prepare Full-Length cDNA Libraries for Rapid Discovery of New Genes
Piero Carninci, Yuko Shibata, Norihito Hayatsu, Yuichi Sugahara, Kazuhiro Shibata, Masayoshi Itoh, Hideaki Konno, Yasushi Okazaki, Masami Muramatsu, Yoshihide Hayashizaki
Genome Res. 2000 Oct; 10(10): 1617–1630. doi: 10.1101/gr.145100
PMCID:
PMC310980
AbstractArticlePDF–1.4M

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