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Select item 111895381.

Association of mitochondrial phosphoenolpyruvate carboxykinase with prognosis and immune regulation in hepatocellular carcinoma

Chenxuan Li, En-di Zhang, Youzhi Ye, Zhongyun Xiao, Hanfei Huang, Zhong Zeng

Sci Rep. 2024; 14: 14051. Published online 2024 Jun 18. doi: 10.1038/s41598-024-64907-7

PMCID:: PMC11189538

Abstract Article PDF–16M

Select item 98834442.

Mitochondrial phosphoenolpyruvate carboxykinase promotes tumor growth in estrogen receptor‐positive breast cancer via regulation of the mTOR pathway

Hui‐Ping Hsu, Pei‐Yi Chu, Tsung‐Ming Chang, Kuo‐Wei Huang, Wen‐Chun Hung, Shih Sheng Jiang, Hui‐You Lin, Hui‐Jen Tsai

Cancer Med. 2023 Jan; 12(2): 1588–1601. Published online 2022 Jun 27. doi: 10.1002/cam4.4969

PMCID:: PMC9883444

Abstract Article PDF–11M

Select item 94025523.

Glycosylation defects, offset by PEPCK-M, drive entosis in breast carcinoma cells

Petra Hyroššová, Marc Aragó, Cristina Muñoz-Pinedo, Francesc Viñals, Pablo M. García-Rovés, Carmen Escolano, Andrés Méndez-Lucas, Jose C. Perales

Cell Death Dis. 2022 Aug; 13(8): 730. Published online 2022 Aug 24. doi: 10.1038/s41419-022-05177-x

PMCID:: PMC9402552

Abstract Article PDF–2.6M

Select item 85443274.

A novel mutation in PCK2 gene causes primary angle-closure glaucoma

Menghan Xu, Jin Yang, Jiayue Sun, Xuemei Xing, Zheng Liu, Tao Liu

Aging (Albany NY) 2021 Oct 15; 13(19): 23338–23347. Published online 2021 Oct 14. doi: 10.18632/aging.203627

PMCID:: PMC8544327

Abstract Article PDF–1.0M

Select item 75460015.

Restoring the epigenetically silenced PCK2 suppresses renal cell carcinoma progression and increases sensitivity to sunitinib by promoting endoplasmic reticulum stress

Zhiyong Xiong, Changfei Yuan, Jian shi, Wei Xiong, Yu Huang, Wen Xiao, Hongmei Yang, Ke Chen, Xiaoping Zhang

Theranostics. 2020; 10(25): 11444–11461. Published online 2020 Sep 15. doi: 10.7150/thno.48469

PMCID:: PMC7546001

Abstract Article PDF–5.5M

Select item 69166356.

Mitochondrial Phosphoenolpyruvate Carboxykinase Regulates Osteogenic Differentiation by Modulating AMPK/ULK1‐Dependent Autophagy

Zheng Li, Xuenan Liu, Yuan Zhu, Yangge Du, Xuejiao Liu, Longwei Lv, Xiao Zhang, Yunsong Liu, Ping Zhang, Yongsheng Zhou

Stem Cells. 2019 Dec; 37(12): 1542–1555. Published online 2019 Oct 14. doi: 10.1002/stem.3091

PMCID:: PMC6916635

Abstract Article PDF–14M

Select item 56133517.

Kinetic and functional properties of human mitochondrial phosphoenolpyruvate carboxykinase

Miriam Escós, Pedro Latorre, Jorge Hidalgo, Ramón Hurtado-Guerrero, José Alberto Carrodeguas, Pascual López-Buesa

Biochem Biophys Rep. 2016 Sep; 7: 124–129. Published online 2016 Jun 8. doi: 10.1016/j.bbrep.2016.06.007

PMCID:: PMC5613351

Abstract Article PDF–634K

Select item 46561118.

PEPCK coordinates the regulation of central carbon metabolism to promote cancer cell growth

Emily Montal, Ruby Dewi, Kavita Bhalla, Lihui Ou, Bor Jang Hwang, Ashley Ropell, Chris Gordon, Wan-Ju Liu, Ralph J. DeBerardinis, Jessica Sudderth, William Twaddel, Lazlo Boros, Kenneth Shroyer, Sekhar Duraisamy, Ronny Drapkin, R. Scott Powers, Jason M. Rohde, Matthew B. Boxer, Kwok-Kin Wong, Geoffrey D Girnun

Mol Cell. Author manuscript; available in PMC 2016 Nov 19.

Published in final edited form as: Mol Cell. 2015 Nov 19; 60(4): 571–583. Published online 2015 Oct 17. doi: 10.1016/j.molcel.2015.09.025

PMCID:: PMC4656111

Abstract Article PDF–1.6M

Select item 40162849.

Expression of phosphoenolpyruvate carboxykinase linked to chemoradiation susceptibility of human colon cancer cells

Ji-Won Park, Seung Cheol Kim, Won Ki Kim, Jun Pyu Hong, Kyung-Hee Kim, Hyun Yang Yeo, Jae Yong Lee, M Sun Kim, Jong Heon Kim, Se Young Yang, Dae Yong Kim, Jae Hwan Oh, Jae Youl Cho, Byong Chul Yoo

BMC Cancer. 2014; 14: 160. Published online 2014 Mar 6. doi: 10.1186/1471-2407-14-160

PMCID:: PMC4016284

Abstract Article PDF–2.8M

Select item 121959310.

Human mitochondrial phosphoenolpyruvate carboxykinase 2 gene. Structure, chromosomal localization and tissue-specific expression.

S Modaressi, K Brechtel, B Christ, K Jungermann

Biochem J. 1998 Jul 15; 333(Pt 2): 359–366. doi: 10.1042/bj3330359

PMCID:: PMC1219593

Summary PDF–1.7M

Select item 121727811.

Molecular cloning, sequencing and expression of the cDNA of the mitochondrial form of phosphoenolpyruvate carboxykinase from human liver.

S Modaressi, B Christ, J Bratke, S Zahn, T Heise, K Jungermann

Biochem J. 1996 May 1; 315(Pt 3): 807–814. doi: 10.1042/bj3150807

PMCID:: PMC1217278

Summary PDF–874K

Select item 937941812.

Role of PCK2 in the proliferation of vascular smooth muscle cells in neointimal hyperplasia

Dai Sik Ko, Junho Kang, Hye Jin Heo, Eun Kyoung Kim, Kihun Kim, Jin Mo Kang, YunJae Jung, Seung Eun Baek, Yun Hak Kim

Int J Biol Sci. 2022; 18(13): 5154–5167. Published online 2022 Aug 8. doi: 10.7150/ijbs.75577

PMCID:: PMC9379418

Abstract Article PDF–2.6M

Select item 819047813.

Phosphoenolpyruvate carboxykinase in cell metabolism: Roles and mechanisms beyond gluconeogenesis

Shuo Yu, Simin Meng, Meixiang Xiang, Hong Ma

Mol Metab. 2021 Nov; 53: 101257. Published online 2021 May 18. doi: 10.1016/j.molmet.2021.101257

PMCID:: PMC8190478

Abstract Article PDF–3.1M

Select item 812633214.

Proteomic Analysis of Hepatocellular Carcinoma Tissues With Encapsulation Shows Up-regulation of Leucine Aminopeptidase 3 and Phosphoenolpyruvate Carboxykinase 2

KEISUKE KUHARA, TAKAO KITAGAWA, BYRON BARON, KAZUHIRO TOKUDA, KAZUHIKO SAKAMOTO, HIROAKI NAGANO, KAZUYUKI NAKAMURA, MASANOBU KOBAYASHI, HIROKI NAGAYASU, YASUHIRO KURAMITSU

Cancer Genomics Proteomics. 2021 May-Jun; 18(3): 307–316. Published online 2021 May 3. doi: 10.21873/cgp.20261

PMCID:: PMC8126332

Abstract Article PDF–2.3M

Select item 769296715.

PURα Promotes the Transcriptional Activation of PCK2 in Esophageal Squamous Cell Carcinoma Cells

Yan Sun, Jiajia Gao, Zongpan Jing, Yan Zhao, Yulin Sun, Xiaohang Zhao

Genes (Basel) 2020 Nov; 11(11): 1301. Published online 2020 Oct 31. doi: 10.3390/genes11111301

PMCID:: PMC7692967

Abstract Article PDF–4.8M

Select item 413922316.

Mitochondrial Phosphoenolpyruvate Carboxykinase (PEPCK-M) Is a Pro-survival, Endoplasmic Reticulum (ER) Stress Response Gene Involved in Tumor Cell Adaptation to Nutrient Availability

Andrés Méndez-Lucas, Petra Hyroššová, Laura Novellasdemunt, Francesc Viñals, Jose C. Perales

J Biol Chem. 2014 Aug 8; 289(32): 22090–22102. Published online 2014 Jun 27. doi: 10.1074/jbc.M114.566927

PMCID:: PMC4139223

Abstract Article PDF–2.4M

Select item 348133117.

Increased Phosphoenolpyruvate Carboxykinase Gene Expression and Steatosis during Hepatitis C Virus Subgenome Replication: ROLE OF NONSTRUCTURAL COMPONENT 5A AND CCAAT/ENHANCER-BINDING PROTEIN β

Ishtiaq Qadri, Mahua Choudhury, Shaikh Mizanoor Rahman, Trina A. Knotts, Rachel C. Janssen, Jerome Schaack, Mieko Iwahashi, Livia Puljak, Francis R. Simon, Gordan Kilic, J. Gregory Fitz, Jacob E. Friedman

J Biol Chem. 2012 Oct 26; 287(44): 37340–37351. Published online 2012 Sep 6. doi: 10.1074/jbc.M112.384743