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Select item 80948141.

Loss of Inhibitor of Growth (ING‐4) is Implicated in the Pathogenesis and Progression of Human Astrocytomas

George Klironomos, Vasiliki Bravou, Dionysios J Papachristou, George Gatzounis, John Varakis, Ekaterini Parassi, Maria Repanti, Helen Papadaki

Brain Pathol. 2010 Mar; 20(2): 490–497. Published online 2009 Aug 6. doi: 10.1111/j.1750-3639.2009.00325.x

PMCID:: PMC8094814

Abstract Article PDF–484K

Select item 63560152.

The essential role of tumor suppressor gene ING4 in various human cancers and non-neoplastic disorders

Yang Du, Yan Cheng, Guanfang Su

Biosci Rep. 2019 Jan 31; 39(1): BSR20180773. Prepublished online 2019 Jan 14. Published online 2019 Jan 30. doi: 10.1042/BSR20180773

PMCID:: PMC6356015

Abstract Article PDF–894K

Select item 56651453.

Overexpression of Inhibitor of Growth 4 Enhances Radiosensitivity in Non-Small Cell Lung Cancer Cell Line SPC-A1

Xuan Pan, Rui Wang, Haibo Bian, Wei De, Ping Zhang, Chenchen Wei, Zhaoxia Wang

Technol Cancer Res Treat. 2017 Oct; 16(5): 533–545. Published online 2016 Jul 4. doi: 10.1177/1533034616656315

PMCID:: PMC5665145

Abstract Article PDF–1.2M

Select item 53466954.

ING4 suppresses tumor angiogenesis and functions as a prognostic marker in human colorectal cancer

Yansu Chen, Yefei Huang, Pingfu Hou, Zhe Zhang, Yafei Zhang, Weimin Wang, Guixiang Sun, Lichun Xu, Jianwei Zhou, Jin Bai, Junnian Zheng

Oncotarget. 2016 Nov 29; 7(48): 79017–79031. Published online 2016 Oct 27. doi: 10.18632/oncotarget.12984

PMCID:: PMC5346695

Abstract Article PDF–6.0M

Select item 42604665.

Delivery of inhibitor of growth 4 (ING4) gene significantly inhibits proliferation and invasion and promotes apoptosis of human osteosarcoma cells

Mei Li, Ye Zhu, Hongbin Zhang, Lihua Li, Peng He, Hong Xia, Yu Zhang, Chuanbin Mao

Sci Rep. 2014; 4: 7380. Published online 2014 Dec 9. doi: 10.1038/srep07380

PMCID:: PMC4260466

Abstract Article PDF–1.2M

Select item 40664546.

Transient Induction of ING4 by MYC Drives Prostate Epithelial Cell Differentiation and its Disruption Drives Prostate Tumorigenesis

Penny L. Berger, Sander B. Frank, Veronique V. Schulz, Eric A. Nollet, Mathew J. Edick, Brittany Holly, Ting-Tung A. Chang, Galen Hostetter, Suwon Kim, Cindy K. Miranti

Cancer Res. Author manuscript; available in PMC 2015 Jun 15.

Published in final edited form as: Cancer Res. 2014 Jun 15; 74(12): 3357–3368. Published online 2014 Apr 24. doi: 10.1158/0008-5472.CAN-13-3076

PMCID:: PMC4066454

Abstract Article PDF–4.3M

Select item 38554537.

Down-regulation of ING4 is associated with initiation and progression of lung cancer

Qiu-shi Wang, Ming Li, Lin-you Zhang, Yan Jin, Dan-dan Tong, Yang Yu, Jing Bai, Qi Huang, Fang-Li Liu, An Liu, Ki-Young Lee, Song-bin Fu

Histopathology. Author manuscript; available in PMC 2013 Dec 7.

Published in final edited form as: Histopathology. 2010 Aug; 57(2): 271–281. doi: 10.1111/j.1365-2559.2010.03623.x

PMCID:: PMC3855453

Abstract Article PDF–1.0M

Select item 31036058.

Deletion of the inhibitor of growth 4 (ING4) tumor suppressor gene is prevalent in human epidermal growth factor 2 (HER2)-positive breast cancer

Coya Tapia, Inti Zlobec, Sandra Schneider, Ergin Kilic, Uwe Güth, Lukas Bubendorf, Suwon Kim

Hum Pathol. Author manuscript; available in PMC 2011 Jul 1.

Published in final edited form as: Hum Pathol. 2011 Jul; 42(7): 983–990. Published online 2011 Feb 11. doi: 10.1016/j.humpath.2010.10.012

PMCID:: PMC3103605

Abstract Article PDF–1.0M

Select item 28919589.

A dominant mutant allele of the ING4 tumor suppressor found in human cancer cells exacerbates MYC-initiated mouse mammary tumorigenesis

Suwon Kim, Alana L. Welm, Michael J. Bishop

Cancer Res. Author manuscript; available in PMC 2011 Jun 15.

Published in final edited form as: Cancer Res. 2010 Jun 15; 70(12): 5155–5162. Published online 2010 May 25. doi: 10.1158/0008-5472.CAN-10-0425

PMCID:: PMC2891958

Abstract Article PDF–2.4M

Select item 286469410.

Crystallization and preliminary X-ray diffraction analysis of the dimerization domain of the tumour suppressor ING4

Simone Culurgioni, Inés G. Muñoz, Alicia Palacios, Pilar Redondo, Francisco J. Blanco, Guillermo Montoya

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 May 1; 66(Pt 5): 567–570. Published online 2010 Apr 30. doi: 10.1107/S1744309110010080

PMCID:: PMC2864694

Abstract Article PDF–419K

Select item 52894011.

A screen for genes that suppress loss of contact inhibition: Identification of ING4 as a candidate tumor suppressor gene in human cancer

Suwon Kim, Koei Chin, Joe W. Gray, J. Michael Bishop

Proc Natl Acad Sci U S A. 2004 Nov 16; 101(46): 16251–16256. Published online 2004 Nov 4. doi: 10.1073/pnas.0407158101

PMCID:: PMC528940

Abstract Article PDF–405K

Select item 707224512.

Macromolecular Crowding Increases the Affinity of the PHD of ING4 for the Histone H3K4me3 Mark

Alicia Palacios, Francisco J Blanco

Biomolecules. 2020 Feb; 10(2): 234. Published online 2020 Feb 4. doi: 10.3390/biom10020234

PMCID:: PMC7072245

Abstract Article PDF–1.0M

Select item 673907313.

Miz1, a Novel Target of ING4, Can Drive Prostate Luminal Epithelial Cell Differentiation

Penny L. Berger, Mary E. Winn, Cindy K. Miranti

Prostate. Author manuscript; available in PMC 2019 Sep 11.

Published in final edited form as: Prostate. 2017 Jan; 77(1): 49–59. Published online 2016 Aug 16. doi: 10.1002/pros.23249

PMCID:: PMC6739073

Abstract Article PDF–2.1M

Select item 437819814.

SCF^JFK is a bona fide E3 ligase for ING4 and a potent promoter of the angiogenesis and metastasis of breast cancer

Ruorong Yan, Lin He, Zhongwu Li, Xiao Han, Jing Liang, Wenzhe Si, Zhe Chen, Lei Li, Guojia Xie, Wanjin Li, Peiyan Wang, Liandi Lei, Hongquan Zhang, Fei Pei, Dengfeng Cao, Luyang Sun, Yongfeng Shang

Genes Dev. 2015 Mar 15; 29(6): 672–685. doi: 10.1101/gad.254292.114

PMCID:: PMC4378198

Abstract Article PDF–671K

Select item 384491715.

ING4 regulates JWA in angiogenesis and their prognostic value in melanoma patients

J Lu, Y Tang, Y Cheng, G Zhang, A Yip, M Martinka, Z Dong, J Zhou, G Li

Br J Cancer. 2013 Nov 26; 109(11): 2842–2852. Published online 2013 Oct 24. doi: 10.1038/bjc.2013.670

PMCID:: PMC3844917

Abstract Article PDF–2.7M

Select item 374274716.

The ING4 Binding with p53 and Induced p53 Acetylation were Attenuated by Human Papillomavirus 16 E6

Yi Guo, Xiangkai Meng, Qian Wang, Yanan Wang, Hong Shang

PLoS One. 2013; 8(8): e71453. Published online 2013 Aug 13. doi: 10.1371/journal.pone.0071453

PMCID:: PMC3742747

Abstract Article PDF–824K

Select item 346423117.

Negative Regulation of NF-κB by the ING4 Tumor Suppressor in Breast Cancer

Sara A. Byron, Elizabeth Min, Tanya S. Thal, Galen Hostetter, Aprill T. Watanabe, David O. Azorsa, Tanya H. Little, Coya Tapia, Suwon Kim

PLoS One. 2012; 7(10): e46823. Published online 2012 Oct 4. doi: 10.1371/journal.pone.0046823

PMCID:: PMC3464231

Abstract Article PDF–1.4M

Select item 332285418.

Crystal Structure of Inhibitor of Growth 4 (ING4) Dimerization Domain Reveals Functional Organization of ING Family of Chromatin-binding Proteins

Simone Culurgioni, Inés G. Muñoz, Alberto Moreno, Alicia Palacios, Maider Villate, Ignacio Palmero, Guillermo Montoya, Francisco J. Blanco

J Biol Chem. 2012 Mar 30; 287(14): 10876–10884. Published online 2012 Feb 9. doi: 10.1074/jbc.M111.330001

PMCID:: PMC3322854

Abstract Article PDF–2.5M

Select item 325964019.

Molecular Basis of Histone H3K4me3 Recognition by ING4

Alicia Palacios, Inés G. Muñoz, David Pantoja-Uceda, María J. Marcaida, Daniel Torres, José M. Martín-García, Irene Luque, Guillermo Montoya, Francisco J. Blanco

J Biol Chem. 2008 Jun 6; 283(23): 15956–15964. doi: 10.1074/jbc.M710020200

PMCID:: PMC3259640

Abstract Article PDF–966K

Select item 266280820.

Down-regulation of the inhibitor of growth family member 4 (ING4) in different forms of pulmonary fibrosis

Argyris Tzouvelekis, Vassilis Aidinis, Vagelis Harokopos, Andreas Karameris, George Zacharis, Dimitrios Mikroulis, Fotios Konstantinou, Paschalis Steiropoulos, Ioannis Sotiriou, Marios Froudarakis, Ioannis Pneumatikos, Rodoula Tringidou, Demosthenes Bouros

Respir Res. 2009; 10(1): 14. Published online 2009 Feb 27. doi: 10.1186/1465-9921-10-14