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Select item 110560701.

TRPV2 modulates mechanically Induced ATP Release from Human bronchial epithelial cells

Orla M. Dunne, S. Lorraine Martin, Gerard P. Sergeant, Daniel F. McAuley, Cecilia M. O’Kane, Brian Button, Lorcan P. McGarvey, Fionnuala T. Lundy

Respir Res. 2024; 25: 188. Published online 2024 Apr 27. doi: 10.1186/s12931-024-02807-0

PMCID:: PMC11056070

Abstract Article PDF–1.8M

Select item 100741062.

The mechanosensitive TRPV2 calcium channel promotes human melanoma invasiveness and metastatic potential

Kenji F Shoji, Elsa Bayet, Sabrina Leverrier‐Penna, Dahiana Le Devedec, Aude Mallavialle, Séverine Marionneau‐Lambot, Florian Rambow, Raul Perret, Aurélie Joussaume, Roselyne Viel, Alain Fautrel, Amir Khammari, Bruno Constantin, Sophie Tartare‐Deckert, Aubin Penna

EMBO Rep. 2023 Apr; 24(4): e55069. Published online 2023 Feb 6. doi: 10.15252/embr.202255069

PMCID:: PMC10074106

Abstract Article PDF–7.1M

Select item 99171683.

Impact of the TRPV2 Inhibitor on Advanced Heart Failure in Patients with Muscular Dystrophy: Exploratory Study of Biomarkers Related to the Efficacy of Tranilast

Chisato Takahashi, Mariko Oishi, Yuko Iwata, Keiko Maekawa, Tsuyoshi Matsumura

Int J Mol Sci. 2023 Feb; 24(3): 2167. Published online 2023 Jan 21. doi: 10.3390/ijms24032167

PMCID:: PMC9917168

Abstract Article PDF–990K

Select item 97460994.

Predictive value of TRPV2 expression from peripheral blood mononuclear cells on the early recurrence of atrial fibrillation after radiofrequency catheter ablation

Xuebin Ling, Jun Wang, Xue Qin, Chufen Lin, Wei Jie, Yane Chen, Dajia Fu, Yang Yang, Qingwen Meng, Jing Lin, Hui Liu, Tianfa Li, Junli Guo

BMC Cardiovasc Disord. 2022; 22: 546. Published online 2022 Dec 13. doi: 10.1186/s12872-022-02992-0

PMCID:: PMC9746099

Abstract Article PDF–1.7M

Select item 95539075.

Thermal stress involved in TRPV2 promotes tumorigenesis through the pathways of HSP70/27 and PI3K/Akt/mTOR in esophageal squamous cell carcinoma

Rongqi Huang, Shuai Li, Chao Tian, Peng Zhou, Huifang Zhao, Wei Xie, Jie Xiao, Ling Wang, Jean de Dieu Habimana, Zuoxian Lin, Yuchen Yang, Na Cheng, Zhiyuan Li

Br J Cancer. 2022 Nov 1; 127(8): 1424–1439. Published online 2022 Jul 27. doi: 10.1038/s41416-022-01896-2

PMCID:: PMC9553907

Abstract Article PDF–4.4M

Select item 75605236.

TRPV2 interacts with actin and reorganizes submembranous actin cytoskeleton

Manoj Yadav, Chandan Goswami

Biosci Rep. 2020 Oct 30; 40(10): BSR20200118. Published online 2020 Oct 14. doi: 10.1042/BSR20200118

PMCID:: PMC7560523

Abstract Article PDF–3.5M

Select item 74325657.

The Effects of Cannabidiol and Prognostic Role of TRPV2 in Human Endometrial Cancer

Oliviero Marinelli, Maria Beatrice Morelli, Daniela Annibali, Cristina Aguzzi, Laura Zeppa, Sandra Tuyaerts, Consuelo Amantini, Frédéric Amant, Benedetta Ferretti, Federica Maggi, Giorgio Santoni, Massimo Nabissi

Int J Mol Sci. 2020 Aug; 21(15): 5409. Published online 2020 Jul 29. doi: 10.3390/ijms21155409

PMCID:: PMC7432565

Abstract Article PDF–7.0M

Select item 68316818.

The expression and role of TRPV2 in esophageal squamous cell carcinoma

Michihiro Kudou, Atsushi Shiozaki, Yuzo Yamazato, Keita Katsurahara, Toshiyuki Kosuga, Katsutoshi Shoda, Tomohiro Arita, Hirotaka Konishi, Shuhei Komatsu, Takeshi Kubota, Hitoshi Fujiwara, Kazuma Okamoto, Mitsuo Kishimoto, Eiichi Konishi, Yoshinori Marunaka, Eigo Otsuji

Sci Rep. 2019; 9: 16055. Published online 2019 Nov 5. doi: 10.1038/s41598-019-52227-0

PMCID:: PMC6831681

Abstract Article PDF–9.5M

Select item 61918939.

TRPV2-induced Ca²⁺-calcineurin-NFAT signaling regulates differentiation of osteoclast in multiple myeloma

Hua Bai, Huayuan Zhu, Qing Yan, Xuxing Shen, Xiupan Lu, Juejin Wang, Jianyong Li, Lijuan Chen

Cell Commun Signal. 2018; 16: 68. Published online 2018 Oct 16. doi: 10.1186/s12964-018-0280-8

PMCID:: PMC6191893

Abstract Article PDF–5.7M

Select item 616540410.

Ca²⁺ Signaling and IL-8 Secretion in Human Testicular Peritubular Cells Involve the Cation Channel TRPV2

Katja Eubler, Carola Herrmann, Astrid Tiefenbacher, Frank-Michael Köhn, J. Ullrich Schwarzer, Lars Kunz, Artur Mayerhofer

Int J Mol Sci. 2018 Sep; 19(9): 2829. Published online 2018 Sep 19. doi: 10.3390/ijms19092829

PMCID:: PMC6165404

Abstract Article PDF–6.2M

Select item 584493711.

Phagocytosis depends on TRPV2-mediated calcium influx and requires TRPV2 in lipids rafts: alteration in macrophages from patients with cystic fibrosis

Manuella Lévêque, Aubin Penna, Sophie Le Trionnaire, Chantal Belleguic, Benoît Desrues, Graziella Brinchault, Stéphane Jouneau, Dominique Lagadic-Gossmann, Corinne Martin-Chouly

Sci Rep. 2018; 8: 4310. Published online 2018 Mar 9. doi: 10.1038/s41598-018-22558-5

PMCID:: PMC5844937

Abstract Article PDF–3.1M

Select item 493296912.

Rational design and validation of a vanilloid-sensitive TRPV2 ion channel

Fan Yang, Simon Vu, Vladimir Yarov-Yarovoy, Jie Zheng

Proc Natl Acad Sci U S A. 2016 Jun 28; 113(26): E3657–E3666. Published online 2016 Jun 13. doi: 10.1073/pnas.1604180113

PMCID:: PMC4932969

Abstract Article PDF–1.9M

Select item 464881613.

Nerve Growth Factor Regulates Transient Receptor Potential Vanilloid 2 via Extracellular Signal-Regulated Kinase Signaling To Enhance Neurite Outgrowth in Developing Neurons

Matthew R. Cohen, William M. Johnson, Jennifer M. Pilat, Janna Kiselar, Alicia DeFrancesco-Lisowitz, Richard E. Zigmond, Vera Y. Moiseenkova-Bell

Mol Cell Biol. 2015 Dec; 35(24): 4238–4252. Prepublished online 2015 Sep 28. Published online 2015 Nov 17. doi: 10.1128/MCB.00549-15

PMCID:: PMC4648816

Abstract Article PDF–3.8M

Select item 390362514.

An Upregulation in the Expression of Vanilloid Transient Potential Channels 2 Enhances Hypotonicity-Induced Cytosolic Ca²⁺ Rise in Human Induced Pluripotent Stem Cell Model of Hutchinson Gillford Progeria

Chun-Yin Lo, Yung-Wui Tjong, Jenny Chung-Yee Ho, Chung-Wah Siu, Sin-Ying Cheung, Nelson L. Tang, Shan Yu, Hung-Fat Tse, Xiaoqiang Yao

PLoS One. 2014; 9(1): e87273. Published online 2014 Jan 27. doi: 10.1371/journal.pone.0087273

PMCID:: PMC3903625

Abstract Article PDF–1.1M

Select item 366912515.

TRPV2 Mediates Adrenomedullin Stimulation of Prostate and Urothelial Cancer Cell Adhesion, Migration and Invasion

Agathe Oulidi, Alexandre Bokhobza, Dimitra Gkika, Fabien Vanden Abeele, V’yacheslav Lehen’kyi, L’Houcine Ouafik, Brigitte Mauroy, Natalia Prevarskaya

PLoS One. 2013; 8(5): e64885. Published online 2013 May 31. doi: 10.1371/journal.pone.0064885

PMCID:: PMC3669125

Abstract Article PDF–724K

Select item 300113316.

Ca²⁺-Dependent Desensitization of TRPV2 Channels Is Mediated by Hydrolysis of Phosphatidylinositol 4,5-Bisphosphate

Jose Mercado, Ariela Gordon-Shaag, William N. Zagotta, Sharona E. Gordon

J Neurosci. 2010 Oct 6; 30(40): 13338–13347. doi: 10.1523/JNEUROSCI.2108-10.2010

PMCID:: PMC3001133

Abstract Article PDF–1.9M

Select item 224260217.

Crystal structure of the human TRPV2 channel ankyrin repeat domain

Clare J. McCleverty, Eric Koesema, Ardem Patapoutian, Scott A. Lesley, Andreas Kreusch

Protein Sci. 2006 Sep; 15(9): 2201–2206. doi: 10.1110/ps.062357206

PMCID:: PMC2242602

Abstract Article PDF–326K

Select item 1086668518.

Ion channel TRPV2 is critical in enhancing B cell activation and function

Cuifeng Li, Meng Zhao, Xiaohang Liu, Yuxin Li, Bihua Xu, Lina Zhou, Xiaolin Sun, Wenbo Sun, Na Kang, Zhenglin Ji, Tong Li, Haoran An, Fei Wang, Chuan Wu, Jing-Ying Ye, Jing-Ren Zhang, Qingwen Wang, Xiaodong Zhao, Zhanguo Li, Wanli Liu

J Exp Med. 2024 Mar 4; 221(3): e20221042. Published online 2024 Feb 14. doi: 10.1084/jem.20221042

PMCID:: PMC10866685

Abstract Article PDF–5.5M

Select item 972291619.

Cannabinoid non-cannabidiol site modulation of TRPV2 structure and function

Liying Zhang, Charlotte Simonsen, Lucie Zimova, Kaituo Wang, Lavanya Moparthi, Rachelle Gaudet, Maria Ekoff, Gunnar Nilsson, Ute A. Hellmich, Viktorie Vlachova, Pontus Gourdon, Peter M. Zygmunt

Nat Commun. 2022; 13: 7483. Published online 2022 Dec 5. doi: 10.1038/s41467-022-35163-y

PMCID:: PMC9722916

Abstract Article PDF–35M

Select item 899806520.

Oxidative Stress-Induced TRPV2 Expression Increase Is Involved in Diabetic Cataracts and Apoptosis of Lens Epithelial Cells in a High-Glucose Environment

Linghui Chen, Yanzhuo Chen, Wen Ding, Tao Zhan, Jie Zhu, Lesha Zhang, Han Wang, Bing Shen, Yong Wang

Cells. 2022 Apr; 11(7): 1196. Published online 2022 Apr 2. doi: 10.3390/cells11071196

PMCID:: PMC8998065

Abstract Article PDF–4.0M

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PMC Links for Gene (Select 51393) (42)
PMC
Sodium channel protein type 4 subunit alpha [Chelonia mydas]
Sodium channel protein type 4 subunit alpha [Chelonia mydas]
gi|465956744|gb|EMP27097.1||gnl|WGS |UY3_15817

Protein
Homo sapiens MCM3APAS mRNA, partial sequence
Homo sapiens MCM3APAS mRNA, partial sequence
gi|21434712|gb|AF426263.1|

Nucleotide
transient receptor potential cation channel subfamily V member 2 isoform X11 [Ho...
transient receptor potential cation channel subfamily V member 2 isoform X11 [Homo sapiens]
gi|2462555817|ref|XP_054172364.1|

Protein

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