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Items: 1 to 20 of 54

1.
Genetic amplification of PPME1 in gastric and lung cancer and its potential as a novel therapeutic target
Jing Li, Sufang Han, Ziliang Qian, Xinying Su, Shuqiong Fan, Jiangang Fu, Yuanjie Liu, Xiaolu Yin, Zeren Gao, Jingchuan Zhang, De-Hua Yu, Qunsheng Ji
Cancer Biol Ther. 2014 Jan 1; 15(1): 128–134. Published online 2013 Nov 19. doi: 10.4161/cbt.27146
PMCID:
PMC3938515
AbstractArticlePDF–1.5M
2.
A LCMT1-PME-1 methylation equilibrium controls mitotic spindle size
Xiaoyu Xia, Ankur Gholkar, Silvia Senese, Jorge Z Torres
Cell Cycle. 2015 Jun 15; 14(12): 1938–1947. Published online 2015 Apr 3. doi: 10.1080/15384101.2015.1026487
PMCID:
PMC4614068
AbstractArticlePDF–1.0M
3.
Academic cross-fertilization by public screening yields a remarkable class of protein phosphatase methylesterase-1 inhibitors
Daniel A. Bachovchin, Justin T. Mohr, Anna E. Speers, Chu Wang, Jacob M. Berlin, Timothy P. Spicer, Virneliz Fernandez-Vega, Peter Chase, Peter S. Hodder, Stephan C. Schürer, Daniel K. Nomura, Hugh Rosen, Gregory C. Fu, Benjamin F. Cravatt
Proc Natl Acad Sci U S A. 2011 Apr 26; 108(17): 6811–6816. Published online 2011 Mar 11. doi: 10.1073/pnas.1015248108
PMCID:
PMC3084096
AbstractArticlePDF–2.2M
4.
The luciferase-based in vivo protein–protein interaction assay revealed that CHK1 promotes PP2A and PME-1 interaction
Sana Ando, Keiko Tanaka, Maharu Matsumoto, Yuki Oyama, Yuri Tomabechi, Atsushi Yamagata, Mikako Shirouzu, Reiko Nakagawa, Noriaki Okimoto, Makoto Taiji, Koichi Sato, Takashi Ohama
J Biol Chem. 2024 May; 300(5): 107277. Published online 2024 Apr 6. doi: 10.1016/j.jbc.2024.107277
PMCID:
PMC11098961
AbstractArticlePDF–1.2M
5.
PP2A methylesterase PME‐1 suppresses anoikis and is associated with therapy relapse of PTEN‐deficient prostate cancers
Anna Aakula, Aleksi Isomursu, Christian Rupp, Andrew Erickson, Nikhil Gupta, Otto Kauko, Pragya Shah, Artur Padzik, Yuba Raj Pokharel, Amanpreet Kaur, Song‐Ping Li, Lloyd Trotman, Pekka Taimen, Antti Rannikko, Jan Lammerding, Ilkka Paatero, Tuomas Mirtti, Johanna Ivaska, Jukka Westermarck
Mol Oncol. 2023 Jun; 17(6): 1007–1023. Published online 2023 Apr 18. doi: 10.1002/1878-0261.13353
PMCID:
PMC10257411
AbstractArticlePDF–2.0M
6.
DNAH17-AS1 promotes pancreatic carcinoma by increasing PPME1 expression via inhibition of miR-432-5p
Tao Xu, Ting Lei, Si-Qiao Li, Er-Hui Mai, Fei-Hu Ding, Bin Niu
World J Gastroenterol. 2020 Apr 21; 26(15): 1745–1757. Published online 2020 Apr 21. doi: 10.3748/wjg.v26.i15.1745
PMCID:
PMC7183867
AbstractArticlePDF–12M
7.
Glycogen synthase kinase-3β suppresses the expression of protein phosphatase methylesterase-1 through β-catenin
Nana Jin, Ruirui Shi, Yanli Jiang, Dandan Chu, Cheng-Xin Gong, Khalid Iqbal, Fei Liu
Aging (Albany NY) 2019 Nov 15; 11(21): 9672–9688. Published online 2019 Nov 12. doi: 10.18632/aging.102413
PMCID:
PMC6874473
AbstractArticlePDF–2.9M
8.
NNMT silencing activates tumor suppressor PP2A, inactivates oncogenic STKs and inhibits tumor forming ability
Kamalakannan Palanichamy, Suman Kanji, Nicolaus Gordon, Krishnan Thirumoorthy, John R. Jacob, Kevin T. Litzenberg, Disha Patel, Arnab Chakravarti
Clin Cancer Res. Author manuscript; available in PMC 2018 May 1.
Published in final edited form as: Clin Cancer Res. 2017 May 1; 23(9): 2325–2334. Published online 2016 Nov 3. doi: 10.1158/1078-0432.CCR-16-1323
PMCID:
PMC5413402
AbstractArticlePDF–2.1M
9.
Phosphoproteome and drug-response effects mediated by the three protein phosphatase 2A inhibitor proteins CIP2A, SET, and PME-1
Otto Kauko, Susumu Y. Imanishi, Evgeny Kulesskiy, Laxman Yetukuri, Teemu Daniel Laajala, Mukund Sharma, Karolina Pavic, Anna Aakula, Christian Rupp, Mikael Jumppanen, Pekka Haapaniemi, Luyao Ruan, Bhagwan Yadav, Veronika Suni, Taru Varila, Garry L. Corthals, Jüri Reimand, Krister Wennerberg, Tero Aittokallio, Jukka Westermarck
J Biol Chem. 2020 Mar 27; 295(13): 4194–4211. Published online 2020 Feb 18. doi: 10.1074/jbc.RA119.011265
PMCID:
PMC7105317
AbstractArticlePDF–3.4M
10.
Identification and Characterization of an Alternatively Spliced Isoform of the Human Protein Phosphatase 2Aα Catalytic Subunit
Deivid L. S. Migueleti, Juliana H. C. Smetana, Hugo F. Nunes, Jörg Kobarg, Nilson I. T. Zanchin
J Biol Chem. 2012 Feb 10; 287(7): 4853–4862. Published online 2011 Dec 13. doi: 10.1074/jbc.M111.283341
PMCID:
PMC3281656
AbstractArticlePDF–1.8M
11.
PME-1 protects ERK pathway activity from protein phosphatase 2A-mediated inactivation in human malignant glioma
Pietri Puustinen, Melissa R. Junttila, Sari Vanhatupa, Anna A. Sablina, Melissa E. Hector, Kaisa Teittinen, Olayinka Raheem, Kirsi Ketola, Shujun Lin, Juergen Kast, Hannu Haapasalo, William C. Hahn, Jukka Westermarck
Cancer Res. Author manuscript; available in PMC 2010 Apr 1.
Published in final edited form as: Cancer Res. 2009 Apr 1; 69(7): 2870–2877. Published online 2009 Mar 17. doi: 10.1158/0008-5472.CAN-08-2760
PMCID:
PMC2810347
AbstractArticlePDF–1.0M
12.
A Protein Phosphatase Methylesterase (PME-1) Is One of Several Novel Proteins Stably Associating with Two Inactive Mutants of Protein Phosphatase 2A
Egon Ogris, Xianxing Du, Kasey C. Nelson, Elsa K. Mak, Xing Xian Yu, William S. Lane, David C. Pallas
J Biol Chem. Author manuscript; available in PMC 2012 Nov 21.
Published in final edited form as: J Biol Chem. 1999 May 14; 274(20): 14382–14391. doi: 10.1074/jbc.274.20.14382
PMCID:
PMC3503312
AbstractArticlePDF–1.8M
13.
Interaction between Salt-inducible Kinase 2 and Protein Phosphatase 2A Regulates the Activity of Calcium/Calmodulin-dependent Protein Kinase I and Protein Phosphatase Methylesterase-1
Chia-Wei Lee, Fu-Chia Yang, Hsin-Yun Chang, Hanyi Chou, Bertrand Chin-Ming Tan, Sheng-Chung Lee
J Biol Chem. 2014 Jul 25; 289(30): 21108–21119. Published online 2014 May 19. doi: 10.1074/jbc.M113.540229
PMCID:
PMC4110314
AbstractArticlePDF–2.3M
14.
Long non-coding RNA SLC25A21-AS1 inhibits the development of epithelial ovarian cancer by specifically inducing PTBP3 degradation
Sihui Li, Shizhen Shen, Wanzhong Ge, Yixuan Cen, Songfa Zhang, Xiaodong Cheng, Xinyu Wang, Xing Xie, Weiguo Lu
Biomark Res. 2023; 11: 12. Published online 2023 Jan 30. doi: 10.1186/s40364-022-00432-x
Correction in:
Biomark Res. 2024; 12: 108.
PMCID:
PMC9885650
AbstractArticlePDF–11M
15.
A PP2A Phosphatase High Density Interaction Network Identifies a Novel Striatin-interacting Phosphatase and Kinase Complex Linked to the Cerebral Cavernous Malformation 3 (CCM3) Protein
Marilyn Goudreault, Lisa M. D’Ambrosio, Michelle J. Kean, Michael J. Mullin, Brett G. Larsen, Amy Sanchez, Sidharth Chaudhry, Ginny I. Chen, Frank Sicheri, Alexey I. Nesvizhskii, Ruedi Aebersold, Brian Raught, Anne-Claude Gingras
Mol Cell Proteomics. 2009 Jan; 8(1): 157–171. doi: 10.1074/mcp.M800266-MCP200
PMCID:
PMC2621004
AbstractArticlePDF–641K
16.
Relevance Rank Platform (RRP) for Functional Filtering of High Content Protein–Protein Interaction Data
Yuba Raj Pokharel, Jani Saarela, Agnieszka Szwajda, Christian Rupp, Anne Rokka, Shibendra Kumar Lal Karna, Kaisa Teittinen, Garry Corthals, Olli Kallioniemi, Krister Wennerberg, Tero Aittokallio, Jukka Westermarck
Mol Cell Proteomics. 2015 Dec; 14(12): 3274–3283. Published online 2015 Oct 23. doi: 10.1074/mcp.M115.050773
PMCID:
PMC4762622
AbstractArticlePDF–1.4M
17.
Energy stress-induced lncRNA FILNC1 represses c-Myc-mediated energy metabolism and inhibits renal tumor development
Zhen-Dong Xiao, Leng Han, Hyemin Lee, Li Zhuang, Yilei Zhang, Joelle Baddour, Deepak Nagrath, Christopher G. Wood, Jian Gu, Xifeng Wu, Han Liang, Boyi Gan
Nat Commun. 2017; 8: 783. Published online 2017 Oct 4. doi: 10.1038/s41467-017-00902-z
PMCID:
PMC5627275
AbstractArticlePDF–1.1M
18.
An integrated workflow for charting the human interaction proteome: insights into the PP2A system
Timo Glatter, Alexander Wepf, Ruedi Aebersold, Matthias Gstaiger
Mol Syst Biol. 2009; 5: 237. Published online 2009 Jan 20. doi: 10.1038/msb.2008.75
PMCID:
PMC2644174
AbstractArticlePDF–4.5M
19.
Identification of intracellular cavin target proteins reveals cavin-PP1alpha interactions regulate apoptosis
Kerrie-Ann McMahon, Yeping Wu, Yann Gambin, Emma Sierecki, Vikas A. Tillu, Thomas Hall, Nick Martel, Satomi Okano, Shayli Varasteh Moradi, Jayde E. Ruelcke, Charles Ferguson, Alpha S. Yap, Kirill Alexandrov, Michelle M. Hill, Robert G. Parton
Nat Commun. 2019; 10: 3279. Published online 2019 Jul 22. doi: 10.1038/s41467-019-11111-1
PMCID:
PMC6646387
AbstractArticlePDF–7.0M
20.
14-3-3-affinity purification of over 200 human phosphoproteins reveals new links to regulation of cellular metabolism, proliferation and trafficking.
Mercedes Pozuelo Rubio, Kathryn M Geraghty, Barry H C Wong, Nicola T Wood, David G Campbell, Nick Morrice, Carol Mackintosh
Biochem J. 2004 Apr 15; 379(Pt 2): 395–408. doi: 10.1042/BJ20031797
PMCID:
PMC1224091
SummaryPDF–323K

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