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Select item 103732471.

Diagnostic value and immune infiltration characterization of YTHDF2 as a critical m6A regulator in osteoarthritic synovitis

Ashuai Bian, Changming Wang, Haotian Zhang, Yiqun Yan, Linlin Zhang, Wendan Cheng

J Orthop Surg Res. 2023; 18: 535. Published online 2023 Jul 27. doi: 10.1186/s13018-023-03933-z

PMCID:: PMC10373247

Abstract Article PDF–9.3M

Select item 102361582.

The m⁶A Reader YTHDF2 Promotes Bladder Cancer Progression by Suppressing RIG-I–Mediated Immune Response

Lei Zhang, Yuqing Li, Lingli Zhou, Houhong Zhou, Liefu Ye, Tong Ou, Huaishan Hong, Shiwen Zheng, Ziyu Zhou, Kang Wu, Zeqin Yan, Jean Paul Thiery, Jun Cui, Song Wu

Cancer Res. 2023 Jun 2; 83(11): 1834–1850. Published online 2023 Mar 20. doi: 10.1158/0008-5472.CAN-22-2485

PMCID:: PMC10236158

Abstract Article PDF–15M

Select item 100621403.

YTHDF2 Is Downregulated in Response to Host Shutoff Induced by DNA Virus Infection and Regulates Interferon-Stimulated Gene Expression

Charles R. Hesser, Derek Walsh

J Virol. 2023 Mar; 97(3): e01758-22. Published online 2023 Mar 14. doi: 10.1128/jvi.01758-22

PMCID:: PMC10062140

Abstract Article PDF–4.2M

Select item 99185324.

O-GlcNAcylation of YTHDF2 promotes HBV-related hepatocellular carcinoma progression in an N⁶-methyladenosine-dependent manner

Yang Yang, Yu Yan, Jiaxin Yin, Ni Tang, Kai Wang, Luyi Huang, Jie Hu, Zhongqi Feng, Qingzhu Gao, Ailong Huang

Signal Transduct Target Ther. 2023; 8: 63. Published online 2023 Feb 10. doi: 10.1038/s41392-023-01316-8

PMCID:: PMC9918532

Abstract Article PDF–7.4M

Select item 95962135.

DNA methylation-regulated YTHDF2 correlates with cell migration and immune cell infiltration in glioma

Xiulin Jiang, Xi Chen, Xiaobin Huang, Chunyan Wang, Chenyang Wang, Chenglong Pan, William C. Cho, Zhi Nie, Jun Pu, Weixiang Wang

Aging (Albany NY) 2022 Oct 15; 14(19): 7774–7793. Published online 2022 Jun 2. doi: 10.18632/aging.204104

PMCID:: PMC9596213

Abstract Article PDF–3.5M

Select item 93085536.

N6-Methyladenosine Reader YTHDF2 Enhances Non-Small-Cell Lung Cancer Cell Proliferation and Metastasis through Mediating circ_SFMBT2 Degradation

Jing Xu, Yan Shang, Xiong Qin, Yun Gai, Feng Cai, Hua Xiao, Chen Zhou, Youhui Fu, Xiahui Ge

Contrast Media Mol Imaging. 2022; 2022: 1087622. Published online 2022 Jul 16. doi: 10.1155/2022/1087622

PMCID:: PMC9308553

Abstract Article PDF–4.5M

Select item 81163397.

RNA m⁶A reader YTHDF2 facilitates lung adenocarcinoma cell proliferation and metastasis by targeting the AXIN1/Wnt/β-catenin signaling

Yin Li, Hao Sheng, Feng Ma, Qiang Wu, Jianfang Huang, Qiang Chen, Lianghe Sheng, Xinghai Zhu, Xiaoxi Zhu, Meng Xu

Cell Death Dis. 2021 May; 12(5): 479. Published online 2021 May 13. doi: 10.1038/s41419-021-03763-z

PMCID:: PMC8116339

Abstract Article PDF–2.9M

Select item 79690138.

SUMOylation of YTHDF2 promotes mRNA degradation and cancer progression by increasing its binding affinity with m⁶A-modified mRNAs

Guofang Hou, Xian Zhao, Lian Li, Qianqian Yang, Xiaojia Liu, Caihu Huang, Runhui Lu, Ran Chen, Yanli Wang, Bin Jiang, Jianxiu Yu

Nucleic Acids Res. 2021 Mar 18; 49(5): 2859–2877. Published online 2021 Feb 12. doi: 10.1093/nar/gkab065

PMCID:: PMC7969013

Abstract Article PDF–3.7M

Select item 79623609.

Histone lactylation drives oncogenesis by facilitating m⁶A reader protein YTHDF2 expression in ocular melanoma

Jie Yu, Peiwei Chai, Minyue Xie, Shengfang Ge, Jing Ruan, Xianqun Fan, Renbing Jia

Genome Biol. 2021; 22: 85. Published online 2021 Mar 16. doi: 10.1186/s13059-021-02308-z

PMCID:: PMC7962360

Abstract Article PDF–4.2M

Select item 779438210.

EGFR/SRC/ERK-stabilized YTHDF2 promotes cholesterol dysregulation and invasive growth of glioblastoma

Runping Fang, Xin Chen, Sicong Zhang, Hui Shi, Youqiong Ye, Hailing Shi, Zhongyu Zou, Peng Li, Qing Guo, Li Ma, Chuan He, Suyun Huang

Nat Commun. 2021; 12: 177. Published online 2021 Jan 8. doi: 10.1038/s41467-020-20379-7

PMCID:: PMC7794382

Abstract Article PDF–2.8M

Select item 759910111.

YTHDF2 mediates the mRNA degradation of the tumor suppressors to induce AKT phosphorylation in N6-methyladenosine-dependent way in prostate cancer

Jiangfeng Li, Haiyun Xie, Yufan Ying, Hong Chen, Huaqing Yan, Liujia He, Mingjie Xu, Xin Xu, Zhen Liang, Ben Liu, Xiao Wang, Xiangyi Zheng, Liping Xie

Mol Cancer. 2020; 19: 152. Published online 2020 Oct 29. doi: 10.1186/s12943-020-01267-6

PMCID:: PMC7599101

Abstract Article PDF–9.0M

Select item 726615612.

YTHDF2 destabilizes m⁶A-modified neural-specific RNAs to restrain differentiation in induced pluripotent stem cells

Adam M. Heck, Joseph Russo, Jeffrey Wilusz, Erin Osborne Nishimura, Carol J. Wilusz

RNA. 2020 Jun; 26(6): 739–755. doi: 10.1261/rna.073502.119

PMCID:: PMC7266156

Abstract Article PDF–5.9M

Select item 694939513.

YTHDF2 Binds to 5-Methylcytosine in RNA and Modulates the Maturation of Ribosomal RNA

Xiaoxia Dai, Gwendolyn Gonzalez, Lin Li, Jie Li, Changjun You, Weili Miao, Junchi Hu, Lijuan Fu, Yonghui Zhao, Ruidong Li, Lichao Li, Xuemei Chen, Yanhui Xu, Weifeng Gu, Yinsheng Wang

Anal Chem. Author manuscript; available in PMC 2021 Jan 7.

Published in final edited form as: Anal Chem. 2020 Jan 7; 92(1): 1346–1354. Published online 2019 Dec 23. doi: 10.1021/acs.analchem.9b04505

PMCID:: PMC6949395

Abstract Article PDF–1.2M

Select item 685962014.

YTHDF2 reduction fuels inflammation and vascular abnormalization in hepatocellular carcinoma

Jiajie Hou, He Zhang, Jun Liu, Zhenjun Zhao, Jianye Wang, Zhike Lu, Bian Hu, Jiankui Zhou, Zhicong Zhao, Mingxuan Feng, Haiyan Zhang, Bin Shen, Xingxu Huang, Beicheng Sun, Chuan He, Qiang Xia

Mol Cancer. 2019; 18: 163. Published online 2019 Nov 18. doi: 10.1186/s12943-019-1082-3

Correction in:: Mol Cancer. 2020; 19: 137.

PMCID:: PMC6859620

Abstract Article PDF–7.8M

Select item 578848115.

YTH domain family 2 orchestrates epithelial-mesenchymal transition/proliferation dichotomy in pancreatic cancer cells

Jixiang Chen, Yaocheng Sun, Xiao Xu, Dawei Wang, Junbo He, Hailang Zhou, Ying Lu, Jian Zeng, Fengyi Du, Aihua Gong, Min Xu

Cell Cycle. 2017; 16(23): 2259–2271. Published online 2017 Nov 14. doi: 10.1080/15384101.2017.1380125

PMCID:: PMC5788481

Abstract Article PDF–1.7M

Select item 1123731016.

基于YTHDF2介导凋亡相关因子降解途径研究牙龈卟啉单胞菌协助食管癌免疫逃逸

杨泽, 张秀森, 张旭东, 柳颖, 张嘉诚, 原翔

Nan Fang Yi Ke Da Xue Xue Bao. 2024 Jun 20; 44(6): 1159–1165. Chinese. doi: 10.12122/j.issn.1673-4254.2024.06.17

PMCID:: PMC11237310

Abstract Article PDF–4.9M

Select item 1063706217.

YTHDF2 promotes gallbladder cancer progression and gemcitabine resistance via m6A‐dependent DAPK3 degradation

Xuesong Bai, Jiemin Chen, Wenqin Zhang, Shengnan Zhou, Liangbo Dong, Jianhao Huang, Xiaodong He

Cancer Sci. 2023 Nov; 114(11): 4299–4313. Published online 2023 Sep 12. doi: 10.1111/cas.15953

PMCID:: PMC10637062

Abstract Article PDF–28M

Select item 1055851418.

YTHDF2 facilitates aggresome formation via UPF1 in an m⁶A-independent manner

Hyun Jung Hwang, Tae Lim Park, Hyeong-In Kim, Yeonkyoung Park, Geunhee Kim, Chiyeol Song, Won-Ki Cho, Yoon Ki Kim

Nat Commun. 2023; 14: 6248. Published online 2023 Oct 6. doi: 10.1038/s41467-023-42015-w

PMCID:: PMC10558514

Abstract Article PDF–5.8M

Select item 1052065219.

HSP90β Impedes STUB1‐Induced Ubiquitination of YTHDF2 to Drive Sorafenib Resistance in Hepatocellular Carcinoma

Yuning Liao, Yuan Liu, Cuifu Yu, Qiucheng Lei, Ji Cheng, Weiyao Kong, Yuanhui Yu, Xuefen Zhuang, Wenshuang Sun, Shusha Yin, Gengxi Cai, Hongbiao Huang

Adv Sci (Weinh) 2023 Sep; 10(27): 2302025. Published online 2023 Jul 28. doi: 10.1002/advs.202302025

PMCID:: PMC10520652

Abstract Article PDF–7.3M

Select item 987240720.

The mechanism underlying redundant functions of the YTHDF proteins

Zhongyu Zou, Caraline Sepich-Poore, Xiaoming Zhou, Jiangbo Wei, Chuan He

Genome Biol. 2023; 24: 17. Published online 2023 Jan 24. doi: 10.1186/s13059-023-02862-8

PMCID:: PMC9872407

Abstract Article PDF–3.5M

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YTH domain-containing family protein 2 isoform 1 [Homo sapiens]
YTH domain-containing family protein 2 isoform 1 [Homo sapiens]
gi|290542345|ref|NP_001166599.1|

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