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Select item 99546851.

CXXC5 Mediates DHT-Induced Androgenetic Alopecia via PGD₂

Yeong Chan Ryu, Jiyeon Park, You-Rin Kim, Sehee Choi, Geon-Uk Kim, Eunhwan Kim, Yumi Hwang, Heejene Kim, Gyoonhee Han, Soung-Hoon Lee, Kang-Yell Choi

Cells. 2023 Feb; 12(4): 555. Published online 2023 Feb 9. doi: 10.3390/cells12040555

PMCID:: PMC9954685

Abstract Article PDF–4.0M

Select item 98605002.

Zinc-finger protein CXXC5 promotes breast carcinogenesis by regulating the TSC1/mTOR signaling pathway

Wenjuan Wang, Zhaohan Zhang, Minghui Zhao, Yu Wang, Yuze Ge, Lin Shan

J Biol Chem. 2023 Jan; 299(1): 102812. Published online 2022 Dec 17. doi: 10.1016/j.jbc.2022.102812

PMCID:: PMC9860500

Abstract Article PDF–5.8M

Select item 84133303.

A prelude to the proximity interaction mapping of CXXC5

Gamze Ayaz, Gizem Turan, Çağla Ece Olgun, Gizem Kars, Burcu Karakaya, Kerim Yavuz, Öykü Deniz Demiralay, Tolga Can, Mesut Muyan, Pelin Yaşar

Sci Rep. 2021; 11: 17587. Published online 2021 Sep 2. doi: 10.1038/s41598-021-97060-6

PMCID:: PMC8413330

Abstract Article PDF–3.7M

Select item 51228964.

Estradiol-Estrogen Receptor α Mediates the Expression of the CXXC5 Gene through the Estrogen Response Element-Dependent Signaling Pathway

Pelin Yaşar, Gamze Ayaz, Mesut Muyan

Sci Rep. 2016; 6: 37808. Published online 2016 Nov 25. doi: 10.1038/srep37808

PMCID:: PMC5122896

Abstract Article PDF–1.2M

Select item 44638095.

Downregulation of the Wnt inhibitor CXXC5 predicts a better prognosis in acute myeloid leukemia

Andrea Kühnl, Peter J. M. Valk, Mathijs A. Sanders, Adam Ivey, Robert K. Hills, Ken I. Mills, Rosemary E. Gale, Martin F. Kaiser, Richard Dillon, Melanie Joannides, Amanda Gilkes, Torsten Haferlach, Susanne Schnittger, Estelle Duprez, David C. Linch, Ruud Delwel, Bob Löwenberg, Claudia D. Baldus, Ellen Solomon, Alan K. Burnett, David Grimwade

Blood. 2015 May 7; 125(19): 2985–2994. Prepublished online 2015 Mar 24. doi: 10.1182/blood-2014-12-613703

PMCID:: PMC4463809

Abstract Article

Select item 44136186.

Expression of the potential therapeutic target CXXC5 in primary acute myeloid leukemia cells - high expression is associated with adverse prognosis as well as altered intracellular signaling and transcriptional regulation

Øystein Bruserud, Håkon Reikvam, Hanne Fredly, Jørn Skavland, Karen-Marie Hagen, Tuyen Thy van Hoang, Annette K. Brenner, Amir Kadi, Audrey Astori, Bjørn Tore Gjertsen, Frederic Pendino

Oncotarget. 2015 Feb; 6(5): 2794–2811. Published online 2014 Dec 26. doi: 10.18632/oncotarget.3056

PMCID:: PMC4413618

Abstract Article PDF–1.3M

Select item 38245417.

CXXC5 (Retinoid-Inducible Nuclear Factor, RINF) is a Potential Therapeutic Target in High-Risk Human Acute Myeloid Leukemia

Audrey Astori, Hanne Fredly, Thomas Aquinas Aloysius, Lars Bullinger, Véronique Mansat-De Mas, Pierre de la Grange, François Delhommeau, Karen Marie Hagen, Christian Récher, Isabelle Dusanter-Fourt, Stian Knappskog, Johan Richard Lillehaug, Frédéric Pendino, Øystein Bruserudg

Oncotarget. 2013 Sep; 4(9): 1438–1448. Published online 2013 Aug 15. doi: 10.18632/oncotarget.1195

PMCID:: PMC3824541

Abstract Article PDF–852K

Select item 89825078.

Inhibition of CXXC5 function reverses obesity‐related metabolic diseases

Seol Hwa Seo, Eunhwan Kim, Soung‐Hoon Lee, Yong‐ho Lee, Dai Hoon Han, Hyesun Go, Je Kyung Seong, Kang‐Yell Choi

Clin Transl Med. 2022 Apr; 12(4): e742. Published online 2022 Apr 5. doi: 10.1002/ctm2.742

PMCID:: PMC8982507

Abstract Article PDF–7.7M

Select item 87190999.

The epigenetic regulator RINF (CXXC5) maintains SMAD7 expression in human immature erythroid cells and sustains red blood cell expansion

Audrey Astori, Gabriel Matherat, Isabelle Munoz, Emilie-Fleur Gautier, Didier Surdez, Yaël Zermati, Frédérique Verdier, Sakina Zaidi, Vincent Feuillet, Amir Kadi, Evelyne Lauret, Olivier Delattre, Carine Lefèvre, Michaela Fontenay, Evelyne Ségal-Bendirdjian, Isabelle Dusanter-Fourt, Didier Bouscary, Olivier Hermine, Patrick Mayeux, Frédéric Pendino

Haematologica. 2022 Jan 1; 107(1): 268–283. Published online 2020 Nov 26. doi: 10.3324/haematol.2020.263558

PMCID:: PMC8719099

Abstract Article PDF–2.5M

Select item 645885010.

CXXC5 mediates growth plate senescence and is a target for enhancement of longitudinal bone growth

Sehee Choi, Hyun-Yi Kim, Pu-Hyeon Cha, Seol Hwa Seo, Chulho Lee, Yejoo Choi, Wookjin Shin, Yunseok Heo, Gyoonhee Han, Weontae Lee, Kang-Yell Choi

Life Sci Alliance. 2019 Apr; 2(2): e201800254. Published online 2019 Apr 10. doi: 10.26508/lsa.201800254

PMCID:: PMC6458850

Abstract Article PDF–2.9M

Select item 1047411411.

Inhibiting the cytosolic function of CXXC5 accelerates diabetic wound healing by enhancing angiogenesis and skin repair

Eunhwan Kim, Seol Hwa Seo, Yumi Hwang, Yeong Chan Ryu, Heejene Kim, Kyoung-Mi Lee, Jin Woo Lee, Kwang Hwan Park, Kang-Yell Choi

Exp Mol Med. 2023 Aug; 55(8): 1770–1782. Published online 2023 Aug 1. doi: 10.1038/s12276-023-01064-3

PMCID:: PMC10474114

Abstract Article PDF–7.3M

Select item 449341112.

The Dishevelled-binding protein CXXC5 negatively regulates cutaneous wound healing

Soung-Hoon Lee, Mi-Yeon Kim, Hyun-Yi Kim, Young-Mi Lee, Heesu Kim, Kyoung Ae Nam, Mi Ryung Roh, Do Sik Min, Kee Yang Chung, Kang-Yell Choi

J Exp Med. 2015 Jun 29; 212(7): 1061–1080. doi: 10.1084/jem.20141601

PMCID:: PMC4493411

Abstract Article PDF–6.7M

Select item 286320713.

A Novel Wilms Tumor 1 (WT1) Target Gene Negatively Regulates the WNT Signaling Pathway

Myoung Shin Kim, Seung Kew Yoon, Frank Bollig, Jirouta Kitagaki, Wonhee Hur, Nathan J. Whye, Yun-Ping Wu, Miguel N. Rivera, Jik Young Park, Ho-Shik Kim, Karim Malik, Daphne W. Bell, Christoph Englert, Alan O. Perantoni, Sean Bong Lee

J Biol Chem. 2010 May 7; 285(19): 14585–14593. Published online 2010 Mar 10. doi: 10.1074/jbc.M109.094334

PMCID:: PMC2863207

Abstract Article PDF–1.5M

Select item 634919714.

CXXC5: A novel regulator and coordinator of TGF‐β, BMP and Wnt signaling

Xiangyang Xiong, Shuo Tu, Jianbin Wang, Shiwen Luo, Xiaohua Yan

J Cell Mol Med. 2019 Feb; 23(2): 740–749. Published online 2018 Nov 27. doi: 10.1111/jcmm.14046

PMCID:: PMC6349197

Abstract Article PDF–427K

Select item 522031415.

KANK1 inhibits cell growth by inducing apoptosis though regulating CXXC5 in human malignant peripheral nerve sheath tumors

Zhibin Cui, Yingjia Shen, Kenny H. Chen, Suresh K. Mittal, Jer-Yen Yang, GuangJun Zhang

Sci Rep. 2017; 7: 40325. Published online 2017 Jan 9. doi: 10.1038/srep40325

Correction in:: Sci Rep. 2017; 7: 46392.

PMCID:: PMC5220314

Abstract Article PDF–1.9M

Select item 357582216.

Oxygen-dependent expression of cytochrome c oxidase subunit 4-2 gene expression is mediated by transcription factors RBPJ, CXXC5 and CHCHD2

Siddhesh Aras, Oleg Pak, Natascha Sommer, Russell Finley, Jr, Maik Hüttemann, Norbert Weissmann, Lawrence I. Grossman

Nucleic Acids Res. 2013 Feb; 41(4): 2255–2266. Published online 2013 Jan 8. doi: 10.1093/nar/gks1454

PMCID:: PMC3575822

Abstract Article PDF–4.7M

Select item 31093417.

Cloning and Functional Analysis of cDNAs with Open Reading Frames for 300 Previously Undefined Genes Expressed in CD34+ Hematopoietic Stem/Progenitor Cells

Qing-Hua Zhang, Min Ye, Xin-Yan Wu, Shuang-Xi Ren, Meng Zhao, Chun-Jun Zhao, Gang Fu, Yu Shen, Hui-Yong Fan, Gang Lu, Ming Zhong, Xiang-Ru Xu, Ze-Guang Han, Ji-Wang Zhang, Jiong Tao, Qiu-Hua Huang, Jun Zhou, Geng-Xi Hu, Jian Gu, Sai-Juan Chen, Zhu Chen

Genome Res. 2000 Oct; 10(10): 1546–1560. doi: 10.1101/gr.140200

PMCID:: PMC310934

Abstract Article PDF–1.3M

Select item 13914618.

Large-Scale Concatenation cDNA Sequencing

Wei Yu, Björn Andersson, Kim C. Worley, Donna M. Muzny, Yan Ding, Wen Liu, Jennifer Y. Ricafrente, Meredith A. Wentland, Greg Lennon, Richard A. Gibbs

Genome Res. 1997 Apr; 7(4): 353–358. doi: 10.1101/gr.7.4.353

PMCID:: PMC139146

Abstract Article PDF–62K

Select item 44214819.

Functional Proteomics Mapping of a Human Signaling Pathway

Frédéric Colland, Xavier Jacq, Virginie Trouplin, Christelle Mougin, Caroline Groizeleau, Alexandre Hamburger, Alain Meil, Jérôme Wojcik, Pierre Legrain, Jean-Michel Gauthier

Genome Res. 2004 Jul; 14(7): 1324–1332. doi: 10.1101/gr.2334104

PMCID:: PMC442148

Abstract Article PDF–290K

Select item 642009720.

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination in sister chromatids

Kyosuke Nakamura, Giulia Saredi, Jordan R. Becker, Benjamin M. Foster, Nhuong V. Nguyen, Tracey Beyer, Laura C. Cesa, Peter A. Faull, Saulius Lukauskas, Thomas Frimurer, J. Ross Chapman, Till Bartke, Anja Groth

Nat Cell Biol. Author manuscript; available in PMC 2019 Aug 25.

Published in final edited form as: Nat Cell Biol. 2019 Mar; 21(3): 311–318. Published online 2019 Feb 25. doi: 10.1038/s41556-019-0282-9

PMCID:: PMC6420097

Article PDF–1.7M

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