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Select item 75847621.

MBIP (MAP3K12 binding inhibitory protein) drives NSCLC metastasis by JNK-dependent activation of MMPs

Joshua Kapere Ochieng, Samrat T. Kundu, Rakhee Bajaj, B. Leticia Rodriguez, Jared J. Fradette, Don L. Gibbons

Oncogene. Author manuscript; available in PMC 2021 Mar 22.

Published in final edited form as: Oncogene. 2020 Oct; 39(43): 6719–6732. Published online 2020 Sep 22. doi: 10.1038/s41388-020-01463-0

PMCID:: PMC7584762

Abstract Article PDF–3.1M

Select item 75734122.

Pathway-Affecting Single Nucleotide Polymorphisms (SNPs) in RPS6KA1 and MBIP Genes are Associated with Breast Cancer Risk

Ghadah Shareefi, Alaa Nabil Turkistani, Ahmed Alsayyah, Haitham Kussaibi, Maha Abdel Had, Khaled R Alkharsah

Asian Pac J Cancer Prev. 2020 Jul; 21(7): 2163–2168. doi: 10.31557/APJCP.2020.21.7.2163

PMCID:: PMC7573412

Abstract Article PDF–456K

Select item 36554123.

Discovery of common variants associated with low TSH levels and thyroid cancer risk

Julius Gudmundsson, Patrick Sulem, Daniel F Gudbjartsson, Jon G Jonasson, Gisli Masson, Huiling He, Aslaug Jonasdottir, Asgeir Sigurdsson, Simon N Stacey, Hrefna Johannsdottir, Hafdis Th Helgadottir, Wei Li, Rebecca Nagy, Matthew D Ringel, Richard T Kloos, Marieke C H de Visser, Theo S Plantinga, Martin den Heijer, Esperanza Aguillo, Angeles Panadero, Enrique Prats, Almudena Garcia-Castaño, Ana De Juan, Fernando Rivera, G Bragi Walters, Hjordis Bjarnason, Laufey Tryggvadottir, Gudmundur I Eyjolfsson, Unnur S Bjornsdottir, Hilma Holm, Isleifur Olafsson, Kristleifur Kristjansson, Hoskuldur Kristvinsson, Olafur T Magnusson, Gudmar Thorleifsson, Jeffrey R Gulcher, Augustine Kong, Lambertus ALM Kiemeney, Thorvaldur Jonsson, Hannes Hjartarson, Jose I Mayordomo, Romana T Netea-Maier, Albert de la Chapelle, Jon Hrafnkelsson, Unnur Thorsteinsdottir, Thorunn Rafnar, Kari Stefansson

Nat Genet. Author manuscript; available in PMC 2013 May 16.

Published in final edited form as: Nat Genet. 2012 Jan 22; 44(3): 319–322. Published online 2012 Jan 22. doi: 10.1038/ng.1046

PMCID:: PMC3655412

Abstract Article PDF–815K

Select item 46415644.

SAGA and ATAC Histone Acetyl Transferase Complexes Regulate Distinct Sets of Genes and ATAC Defines a Class of p300-Independent Enhancers

Arnaud R. Krebs, Krishanpal Karmodiya, Marianne Lindahl-Allen, Kevin Struhl, Làszlò Tora

Mol Cell. Author manuscript; available in PMC 2015 Nov 11.

Published in final edited form as: Mol Cell. 2011 Nov 4; 44(3): 410–423. doi: 10.1016/j.molcel.2011.08.037

PMCID:: PMC4641564

Abstract Article PDF–1.1M

Select item 52407905.

Systematic Identification of Oncogenic EGFR Interaction Partners

Julia Petschnigg, Max Kotlyar, Louise Blair, Igor Jurisica, Igor Stagljar, Robin Ketteler

J Mol Biol. 2017 Jan 20; 429(2): 280–294. doi: 10.1016/j.jmb.2016.12.006

PMCID:: PMC5240790

Abstract Article

Select item 35671756.

A Meta-Analysis of Thyroid-Related Traits Reveals Novel Loci and Gender-Specific Differences in the Regulation of Thyroid Function

Eleonora Porcu, Marco Medici, Giorgio Pistis, Claudia B. Volpato, Scott G. Wilson, Anne R. Cappola, Steffan D. Bos, Joris Deelen, Martin den Heijer, Rachel M. Freathy, Jari Lahti, Chunyu Liu, Lorna M. Lopez, Ilja M. Nolte, Jeffrey R. O'Connell, Toshiko Tanaka, Stella Trompet, Alice Arnold, Stefania Bandinelli, Marian Beekman, Stefan Böhringer, Suzanne J. Brown, Brendan M. Buckley, Clara Camaschella, Anton J. M. de Craen, Gail Davies, Marieke C. H. de Visser, Ian Ford, Tom Forsen, Timothy M. Frayling, Laura Fugazzola, Martin Gögele, Andrew T. Hattersley, Ad R. Hermus, Albert Hofman, Jeanine J. Houwing-Duistermaat, Richard A. Jensen, Eero Kajantie, Margreet Kloppenburg, Ee M. Lim, Corrado Masciullo, Stefano Mariotti, Cosetta Minelli, Braxton D. Mitchell, Ramaiah Nagaraja, Romana T. Netea-Maier, Aarno Palotie, Luca Persani, Maria G. Piras, Bruce M. Psaty, Katri Räikkönen, J. Brent Richards, Fernando Rivadeneira, Cinzia Sala, Mona M. Sabra, Naveed Sattar, Beverley M. Shields, Nicole Soranzo, John M. Starr, David J. Stott, Fred C. G. J. Sweep, Gianluca Usala, Melanie M. van der Klauw, Diana van Heemst, Alies van Mullem, Sita H.Vermeulen, W. Edward Visser, John P. Walsh, Rudi G. J. Westendorp, Elisabeth Widen, Guangju Zhai, Francesco Cucca, Ian J. Deary, Johan G. Eriksson, Luigi Ferrucci, Caroline S. Fox, J. Wouter Jukema, Lambertus A. Kiemeney, Peter P. Pramstaller, David Schlessinger, Alan R. Shuldiner, Eline P. Slagboom, André G. Uitterlinden, Bijay Vaidya, Theo J. Visser, Bruce H. R. Wolffenbuttel, Ingrid Meulenbelt, Jerome I. Rotter, Tim D. Spector, Andrew A. Hicks, Daniela Toniolo, Serena Sanna, Robin P. Peeters, Silvia Naitza

PLoS Genet. 2013 Feb; 9(2): e1003266. Published online 2013 Feb 7. doi: 10.1371/journal.pgen.1003266

PMCID:: PMC3567175

Abstract Article PDF–1.6M

Select item 29102757.

The ATAC acetyl transferase complex controls mitotic progression by targeting non-histone substrates

Meritxell Orpinell, Marjorie Fournier, Anne Riss, Zita Nagy, Arnaud R Krebs, Mattia Frontini, Làszlò Tora

EMBO J. 2010 Jul 21; 29(14): 2381–2394. Published online 2010 Jun 18. doi: 10.1038/emboj.2010.125

PMCID:: PMC2910275

Abstract Article PDF–1.5M

Select item 111155978.

The metazoan ATAC and SAGA coactivator HAT complexes regulate different sets of inducible target genes

Zita Nagy, Anne Riss, Sally Fujiyama, Arnaud Krebs, Meritxell Orpinell, Pascal Jansen, Adrian Cohen, Henk G. Stunnenberg, Shigeaki Kato, Làszlò Tora

Cell Mol Life Sci. 2010 Feb; 67(4): 611–628. Published online 2009 Nov 21. doi: 10.1007/s00018-009-0199-8

PMCID:: PMC11115597

Abstract Article PDF–816K

Select item 26438269.

The Double-Histone-Acetyltransferase Complex ATAC Is Essential for Mammalian Development

Sebastián Guelman, Kenji Kozuka, Yifan Mao, Victoria Pham, Mark J. Solloway, John Wang, Jiansheng Wu, Jennie R. Lill, Jiping Zha

Mol Cell Biol. 2009 Mar; 29(5): 1176–1188. Published online 2008 Dec 22. doi: 10.1128/MCB.01599-08

PMCID:: PMC2643826

Abstract Article PDF–4.1M

Select item 1059183610.

ATAC and SAGA co-activator complexes utilize co-translational assembly, but their cellular localization properties and functions are distinct

Gizem Yayli, Andrea Bernardini, Paulina Karen Mendoza Sanchez, Elisabeth Scheer, Mylène Damilot, Karim Essabri, Bastien Morlet, Luc Negroni, Stéphane D. Vincent, H.T. Marc Timmers, László Tora

Cell Rep. Author manuscript; available in PMC 2023 Oct 23.

Published in final edited form as: Cell Rep. 2023 Sep 26; 42(9): 113099. Published online 2023 Sep 8. doi: 10.1016/j.celrep.2023.113099

PMCID:: PMC10591836

Abstract Article PDF–2.6M

Select item 259071111.

Human ATAC Is a GCN5/PCAF-containing Acetylase Complex with a Novel NC2-like Histone Fold Module That Interacts with the TATA-binding Protein

Yuan-Liang Wang, Francesco Faiola, Muyu Xu, Songqin Pan, Ernest Martinez

J Biol Chem. 2008 Dec 5; 283(49): 33808–33815. doi: 10.1074/jbc.M806936200

PMCID:: PMC2590711

Abstract Article PDF–642K

Select item 108790712.

Scanning the human proteome for calmodulin-binding proteins

Xinchun Shen, C. Alexander Valencia, Jack Szostak, Biao Dong, Rihe Liu

Proc Natl Acad Sci U S A. 2005 Apr 26; 102(17): 5969–5974. Published online 2005 Apr 19. doi: 10.1073/pnas.0407928102

Correction in:: Proc Natl Acad Sci U S A. 2005 Jul 5; 102(27): 9734.

PMCID:: PMC1087907

Abstract Article PDF–362K

Select item 488286713.

Systematic interactome mapping of acute lymphoblastic leukemia cancer gene products reveals EXT-1 tumor suppressor as a Notch1 and FBWX7 common interactor

Sarah Daakour, Leon Juvenal Hajingabo, Despoina Kerselidou, Aurelie Devresse, Richard Kettmann, Nicolas Simonis, Franck Dequiedt, Jean-Claude Twizere

BMC Cancer. 2016; 16: 335. Published online 2016 May 26. doi: 10.1186/s12885-016-2374-2

PMCID:: PMC4882867

Abstract Article PDF–1.8M

Select item 287256114.

An empirical framework for binary interactome mapping

Kavitha Venkatesan, Jean-François Rual, Alexei Vazquez, Ulrich Stelzl, Irma Lemmens, Tomoko Hirozane-Kishikawa, Tong Hao, Martina Zenkner, Xiaofeng Xin, Kwang-II Goh, Muhammed A Yildirim, Nicolas Simonis, Kathrin Heinzmann, Fana Gebreab, Julie M Sahalie, Sebiha Cevik, Christophe Simon, Anne-Sophie de Smet, Elizabeth Dann, Alex Smolyar, Arunachalam Vinayagam, Haiyuan Yu, David Szeto, Heather Borick, Amélie Dricot, Niels Klitgord, Ryan R Murray, Chenwei Lin, Maciej Lalowski, Jan Timm, Kirstin Rau, Charles Boone, Pascal Braun, Michael E Cusick, Frederick P Roth, David E Hill, Jan Tavernier, Erich E Wanker, Albert-László Barabási, Marc Vidal

Nat Methods. Author manuscript; available in PMC 2010 May 18.

Published in final edited form as: Nat Methods. 2009 Jan; 6(1): 83–90. Published online 2008 Dec 7. doi: 10.1038/nmeth.1280

PMCID:: PMC2872561

Abstract Article PDF–1.0M

Select item 386161615.

The HECT Type Ubiquitin Ligase NEDL2 Is Degraded by Anaphase-promoting Complex/Cyclosome (APC/C)-Cdh1, and Its Tight Regulation Maintains the Metaphase to Anaphase Transition

Li Lu, Shaohua Hu, Rongfei Wei, Xiao Qiu, Kefeng Lu, Yesheng Fu, Hongchang Li, Guichun Xing, Dong Li, Ruiyun Peng, Fuchu He, Lingqiang Zhang

J Biol Chem. 2013 Dec 13; 288(50): 35637–35650. Published online 2013 Oct 25. doi: 10.1074/jbc.M113.472076

PMCID:: PMC3861616

Abstract Article PDF–4.4M

Select item 31093416.

Cloning and Functional Analysis of cDNAs with Open Reading Frames for 300 Previously Undefined Genes Expressed in CD34+ Hematopoietic Stem/Progenitor Cells

Qing-Hua Zhang, Min Ye, Xin-Yan Wu, Shuang-Xi Ren, Meng Zhao, Chun-Jun Zhao, Gang Fu, Yu Shen, Hui-Yong Fan, Gang Lu, Ming Zhong, Xiang-Ru Xu, Ze-Guang Han, Ji-Wang Zhang, Jiong Tao, Qiu-Hua Huang, Jun Zhou, Geng-Xi Hu, Jian Gu, Sai-Juan Chen, Zhu Chen

Genome Res. 2000 Oct; 10(10): 1546–1560. doi: 10.1101/gr.140200

PMCID:: PMC310934

Abstract Article PDF–1.3M

Select item 399653717.

Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism

Roser Corominas, Xinping Yang, Guan Ning Lin, Shuli Kang, Yun Shen, Lila Ghamsari, Martin Broly, Maria Rodriguez, Stanley Tam, Shelly A. Wanamaker, Changyu Fan, Song Yi, Murat Tasan, Irma Lemmens, Xingyan Kuang, Nan Zhao, Dheeraj Malhotra, Jacob J. Michaelson, Vladimir Vacic, Michael A. Calderwood, Frederick P. Roth, Jan Tavernier, Steve Horvath, Kourosh Salehi-Ashtiani, Dmitry Korkin, Jonathan Sebat, David E. Hill, Tong Hao, Marc Vidal, Lilia M. Iakoucheva

Nat Commun. 2014; 5: 3650. Published online 2014 Apr 11. doi: 10.1038/ncomms4650