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Select item 101890501.

Elevated MPP6 expression correlates with an unfavorable prognosis, angiogenesis and immune evasion in hepatocellular carcinoma

Qianqian Cheng, Wei Wang, Jing Liu, Zhenyu Lv, Wenbin Ji, Jinhui Yu, Wenting Zhang, Yan Yang

Front Immunol. 2023; 14: 1173848. Published online 2023 May 3. doi: 10.3389/fimmu.2023.1173848

PMCID:: PMC10189050

Abstract Article PDF–30M

Select item 109876442.

Mex-3 RNA binding family member A (MEX3A)/circMPP6 complex promotes colorectal cancer progression by inhibiting autophagy

Ri-Xin Chen, Shui-Dan Xu, Min-Hua Deng, Shi-Hui Hao, Jie-Wei Chen, Xiao-Dan Ma, Wei-Tao Zhuang, Jing-Hua Cao, Yong-Rui Lv, Jin-Long Lin, Si-Yu Li, Gui-Bin Qiao, Dan Xie, Feng-Wei Wang

Signal Transduct Target Ther. 2024; 9: 80. Published online 2024 Apr 2. doi: 10.1038/s41392-024-01787-3

PMCID:: PMC10987644

Abstract Article PDF–5.3M

Select item 79532223.

Multi-ethnic GWAS and meta-analysis of sleep quality identify MPP6 as a novel gene that functions in sleep center neurons

Samar Khoury, Qiao-Ping Wang, Marc Parisien, Pavel Gris, Andrey V Bortsov, Sarah D Linnstaedt, Samuel A McLean, Andrew S Tungate, Tamar Sofer, Jiwon Lee, Tin Louie, Susan Redline, Mari Anneli Kaunisto, Eija A Kalso, Hans Markus Munter, Andrea G Nackley, Gary D Slade, Shad B Smith, Dmitri V Zaykin, Roger B Fillingim, Richard Ohrbach, Joel D Greenspan, William Maixner, G Gregory Neely, Luda Diatchenko

Sleep. 2021 Mar; 44(3): zsaa211. Published online 2020 Oct 9. doi: 10.1093/sleep/zsaa211

PMCID:: PMC7953222

Abstract Article PDF–16M

Select item 17981494.

Prospective 7 year follow up imaging study comparing radiography, ultrasonography, and magnetic resonance imaging in rheumatoid arthritis finger joints

A K Scheel, K‐G A Hermann, S Ohrndorf, C Werner, C Schirmer, J Detert, M Bollow, B Hamm, G A Müller, G R Burmester, M Backhaus

Ann Rheum Dis. 2006 May; 65(5): 595–600. Published online 2005 Sep 28. doi: 10.1136/ard.2005.041814

PMCID:: PMC1798149

Abstract Article PDF–417K

Select item 94108985.

MPP6 stimulates both RRP6 and DIS3 to degrade a specified subset of MTR4-sensitive substrates in the human nucleus

Naoko Fujiwara, Maki Shigemoto, Mizuki Hirayama, Ken-ichi Fujita, Shigeto Seno, Hideo Matsuda, Masami Nagahama, Seiji Masuda

Nucleic Acids Res. 2022 Aug 26; 50(15): 8779–8806. Published online 2022 Jul 29. doi: 10.1093/nar/gkac559

PMCID:: PMC9410898

Abstract Article PDF–17M

Select item 45219816.

Quantifying domain-ligand affinities and specificities by high-throughput holdup assay

Renaud Vincentelli, Katja Luck, Juline Poirson, Jolanta Polanowska, Julie Abdat, Marilyne Blémont, Jeremy Turchetto, François Iv, Kevin Ricquier, Marie-Laure Straub, Anne Forster, Patricia Cassonnet, Jean-Paul Borg, Yves Jacob, Murielle Masson, Yves Nominé, Jérôme Reboul, Nicolas Wolff, Sebastian Charbonnier, Gilles Travé

Nat Methods. Author manuscript; available in PMC 2016 Feb 1.

Published in final edited form as: Nat Methods. 2015 Aug; 12(8): 787–793. Published online 2015 Jun 8. doi: 10.1038/nmeth.3438

PMCID:: PMC4521981

Abstract Article PDF–1.3M

Select item 33799947.

Comprehensive Analysis of Interactions between the Src-Associated Protein in Mitosis of 68 kDa and the Human Src-Homology 3 Proteome

Benedikt Asbach, Christine Ludwig, Kalle Saksela, Ralf Wagner

PLoS One. 2012; 7(6): e38540. Published online 2012 Jun 20. doi: 10.1371/journal.pone.0038540

PMCID:: PMC3379994

Abstract Article PDF–581K

Select item 37140108.

Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis

Cross-Disorder Group of the Psychiatric Genomics Consortium

Lancet. Author manuscript; available in PMC 2014 Apr 20.

Published in final edited form as: Lancet. 2013 Apr 20; 381(9875): 1371–1379. Published online 2013 Feb 28. doi: 10.1016/S0140-6736(12)62129-1

PMCID:: PMC3714010

Abstract Article PDF–878K

Select item 28275389.

A Comprehensive Resource of Interacting Protein Regions for Refining Human Transcription Factor Networks

Etsuko Miyamoto-Sato, Shigeo Fujimori, Masamichi Ishizaka, Naoya Hirai, Kazuyo Masuoka, Rintaro Saito, Yosuke Ozawa, Katsuya Hino, Takanori Washio, Masaru Tomita, Tatsuhiro Yamashita, Tomohiro Oshikubo, Hidetoshi Akasaka, Jun Sugiyama, Yasuo Matsumoto, Hiroshi Yanagawa

PLoS One. 2010; 5(2): e9289. Published online 2010 Feb 24. doi: 10.1371/journal.pone.0009289

PMCID:: PMC2827538

Abstract Article PDF–676K

Select item 794896410.

The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1

Lee D. Harris, Janic Le Pen, Nico Scholz, Juliusz Mieszczanek, Natalie Vaughan, Simon Davis, Georgina Berridge, Benedikt M. Kessler, Mariann Bienz, Julien D.F. Licchesi

J Biol Chem. 2021 Jan-Jun; 296: 100246. Published online 2021 Jan 8. doi: 10.1074/jbc.RA120.015162

PMCID:: PMC7948964

Abstract Article PDF–2.7M

Select item 401998111.

Interaction proteome of human Hippo signaling: modular control of the co‐activator YAP1

Simon Hauri, Alexander Wepf, Audrey van Drogen, Markku Varjosalo, Nic Tapon, Ruedi Aebersold, Matthias Gstaiger

Mol Syst Biol. 2013; 9: 713. Published online 2013 Dec 20. doi: 10.1002/msb.201304750

PMCID:: PMC4019981

Abstract Article PDF–915K

Select item 325365812.

Mapping a Dynamic Innate Immunity Protein Interaction Network Regulating Type I Interferon Production

Shitao Li, Lingyan Wang, Michael Berman, Young-Yun Kong, Martin E. Dorf

Immunity. Author manuscript; available in PMC 2012 Sep 23.

Published in final edited form as: Immunity. 2011 Sep 23; 35(3): 426–440. Published online 2011 Sep 8. doi: 10.1016/j.immuni.2011.06.014

Correction in:: volume 35 on page 647

PMCID:: PMC3253658

Abstract Article PDF–4.2M

Select item 947545313.

The N⁶-methyladenosine-mediated lncRNA WEE2-AS1 promotes glioblastoma progression by stabilizing RPN2

Boyan Li, Rongrong Zhao, Wei Qiu, Ziwen Pan, Shulin Zhao, Yanhua Qi, Jiawei Qiu, Shouji Zhang, Qindong Guo, Yang Fan, Hao Xu, Ming Li, Gang Li, Hao Xue

Theranostics. 2022; 12(14): 6363–6379. Published online 2022 Aug 29. doi: 10.7150/thno.74600

PMCID:: PMC9475453

Abstract Article PDF–4.4M

Select item 44214714.

A Protein Interaction Framework for Human mRNA Degradation

Ben Lehner, Christopher M. Sanderson

Genome Res. 2004 Jul; 14(7): 1315–1323. doi: 10.1101/gr.2122004

PMCID:: PMC442147

Abstract Article PDF–272K

Select item 486124915.

The Scaffold Protein KSR1, A Novel Therapeutic Target for the Treatment of Merlin-Deficient Tumors

Lu Zhou, Jade Lyons-Rimmer, Sylwia Ammoun, Jürgen Müller, Edwin Lasonder, Vikram Sharma, Emanuela Ercolano, David Hilton, Ifeoluwatola Taiwo, Magdalena Barczyk, C. Oliver Hanemann

Oncogene. Author manuscript; available in PMC 2016 Dec 30.

Published in final edited form as: Oncogene. 2016 Jun 30; 35(26): 3443–3453. Published online 2015 Nov 9. doi: 10.1038/onc.2015.404

PMCID:: PMC4861249

Abstract Article PDF–2.5M

Select item 760600816.

BCAR1 promotes proliferation and cell growth in lung adenocarcinoma via upregulation of POLR2A

Chun‐guo Mao, Sha‐sha Jiang, Cheng Shen, Tan Long, Hua Jin, Qun‐You Tan, Bo Deng

Thorac Cancer. 2020 Nov; 11(11): 3326–3336. Published online 2020 Oct 1. doi: 10.1111/1759-7714.13676

PMCID:: PMC7606008

Abstract Article PDF–2.5M

Select item 737208117.

Unbiased Profiling of the Human Proinsulin Biosynthetic Interaction Network Reveals a Role for Peroxiredoxin 4 in Proinsulin Folding

Duc T. Tran, Anita Pottekat, Saiful A. Mir, Salvatore Loguercio, Insook Jang, Alexandre Rosa Campos, Kathleen M. Scully, Reyhaneh Lahmy, Ming Liu, Peter Arvan, William E. Balch, Randal J. Kaufman, Pamela Itkin-Ansari

Diabetes. 2020 Aug; 69(8): 1723–1734. Published online 2020 May 26. doi: 10.2337/db20-0245

PMCID:: PMC7372081

Abstract Article PDF–2.0M

Select item 778549418.

AMPK, a key regulator of metabolism and autophagy, is activated by lysosomal damage via a novel galectin-directed ubiquitin signal transduction system

Jingyue Jia, Bhawana Bissa, Lukas Brecht, Lee Allers, Seong Won Choi, Yuexi Gu, Mark Zbinden, Mark R. Burge, Graham Timmins, Kenneth Hallows, Christian Behrends, Vojo Deretic

Mol Cell. Author manuscript; available in PMC 2021 Mar 5.

Published in final edited form as: Mol Cell. 2020 Mar 5; 77(5): 951–969.e9. Published online 2020 Jan 28. doi: 10.1016/j.molcel.2019.12.028

PMCID:: PMC7785494

Abstract Article PDF–2.9M

Select item 288296119.

Human Chromosome 7: DNA Sequence and Biology

Stephen W. Scherer, Joseph Cheung, Jeffrey R. MacDonald, Lucy R. Osborne, Kazuhiko Nakabayashi, Jo-Anne Herbrick, Andrew R. Carson, Layla Parker-Katiraee, Jennifer Skaug, Razi Khaja, Junjun Zhang, Alexander K. Hudek, Martin Li, May Haddad, Gavin E. Duggan, Bridget A. Fernandez, Emiko Kanematsu, Simone Gentles, Constantine C. Christopoulos, Sanaa Choufani, Dorota Kwasnicka, Xiangqun H. Zheng, Zhongwu Lai, Deborah Nusskern, Qing Zhang, Zhiping Gu, Fu Lu, Susan Zeesman, Malgorzata J. Nowaczyk, Ikuko Teshima, David Chitayat, Cheryl Shuman, Rosanna Weksberg, Elaine H. Zackai, Theresa A. Grebe, Sarah R. Cox, Susan J. Kirkpatrick, Nazneen Rahman, Jan M. Friedman, Henry H. Q. Heng, Pier Giuseppe Pelicci, Francesco Lo-Coco, Elena Belloni, Lisa G. Shaffer, Barbara Pober, Cynthia C. Morton, James F. Gusella, Gail A. P. Bruns, Bruce R. Korf, Bradley J. Quade, Azra H. Ligon, Heather Ferguson, Anne W. Higgins, Natalia T. Leach, Steven R. Herrick, Emmanuelle Lemyre, Chantal G. Farra, Hyung-Goo Kim, Anne M. Summers, Karen W. Gripp, Wendy Roberts, Peter Szatmari, Elizabeth J. T. Winsor, Karl-Heinz Grzeschik, Ahmed Teebi, Berge A. Minassian, Juha Kere, Lluis Armengol, Miguel Angel Pujana, Xavier Estivill, Michael D. Wilson, Ben F. Koop, Sabrina Tosi, Gudrun E. Moore, Andrew P. Boright, Eitan Zlotorynski, Batsheva Kerem, Peter M. Kroisel, Erwin Petek, David G. Oscier, Sarah J. Mould, Hartmut Döhner, Konstanze Döhner, Johanna M. Rommens, John B. Vincent, J. Craig Venter, Peter W. Li, Richard J. Mural, Mark D. Adams, Lap-Chee Tsui

Science. Author manuscript; available in PMC 2010 Jun 9.

Published in final edited form as: Science. 2003 May 2; 300(5620): 767–772. Published online 2003 Apr 10. doi: 10.1126/science.1083423

PMCID:: PMC2882961

Abstract Article PDF–1.2M

Select item 1061767320.

The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation

Xin Gu, Christopher Nardone, Nolan Kamitaki, Aoyue Mao, Stephen J. Elledge, Michael E. Greenberg

Science. Author manuscript; available in PMC 2023 Oct 31.

Published in final edited form as: Science. 2023 Aug 25; 381(6660): eadh5021. Published online 2023 Aug 25. doi: 10.1126/science.adh5021

PMCID:: PMC10617673

Abstract Article PDF–3.6M

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