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Select item 107593621.

The oncogenic role and regulatory mechanism of PGK1 in human non-small cell lung cancer

Tian Tian, Yahui Leng, Bingbing Tang, Xiaoxia Dong, Qiulei Ren, Jingyin Liang, Tianhui Liu, Yanni Liu, Wenxiao Feng, Song Liu, Yang Zhou, Hongyan Zhao, Li Shen

Biol Direct. 2024; 19: 1. Published online 2024 Jan 2. doi: 10.1186/s13062-023-00448-9

PMCID:: PMC10759362

Abstract Article PDF–18M

Select item 95615272.

Loss of stability and unfolding cooperativity in hPGK1 upon gradual structural perturbation of its N-terminal domain hydrophobic core

Juan Luis Pacheco-García, Dmitry S. Loginov, Athi N. Naganathan, Pavla Vankova, Mario Cano-Muñoz, Petr Man, Angel L. Pey

Sci Rep. 2022; 12: 17200. Published online 2022 Oct 13. doi: 10.1038/s41598-022-22088-1

PMCID:: PMC9561527

Abstract Article PDF–5.6M

Select item 88169103.

PGK1 contributes to tumorigenesis and sorafenib resistance of renal clear cell carcinoma via activating CXCR4/ERK signaling pathway and accelerating glycolysis

Yu He, Xixi Wang, Weiliang Lu, Dan Zhang, Lan Huang, Yang Luo, Li Xiong, Haocheng Li, Peng Zhang, Qiu Li, Shufang Liang

Cell Death Dis. 2022 Feb; 13(2): 118. Published online 2022 Feb 4. doi: 10.1038/s41419-022-04576-4

PMCID:: PMC8816910

Abstract Article PDF–6.1M

Select item 86857154.

Molecular mechanism of glycolytic flux control intrinsic to human phosphoglycerate kinase

Hiromasa Yagi, Takuma Kasai, Elisa Rioual, Teppei Ikeya, Takanori Kigawa

Proc Natl Acad Sci U S A. 2021 Dec 14; 118(50): e2112986118. Published online 2021 Dec 10. doi: 10.1073/pnas.2112986118

PMCID:: PMC8685715

Abstract Article PDF–1.4M

Select item 83961875.

Pathological Role of Phosphoglycerate Kinase 1 in Balloon Angioplasty-Induced Neointima Formation

Chun-Hsu Pan, Yi-Chung Chien, Min-Shan Sung, Hui-Yu Huang, Ming-Jyh Sheu, Chieh-Hsi Wu

Int J Mol Sci. 2021 Aug; 22(16): 8822. Published online 2021 Aug 17. doi: 10.3390/ijms22168822

PMCID:: PMC8396187

Abstract Article PDF–2.6M

Select item 73848536.

Activation of PGK1 under hypoxic conditions promotes glycolysis and increases stem cell-like properties and the epithelial-mesenchymal transition in oral squamous cell carcinoma cells via the AKT signalling pathway

Yadong Zhang, Hongshi Cai, Yan Liao, Yue Zhu, Fang Wang, Jinsong Hou

Int J Oncol. 2020 Sep; 57(3): 743–755. Published online 2020 Jun 16. doi: 10.3892/ijo.2020.5083

PMCID:: PMC7384853

Abstract Article PDF–2.1M

Select item 68263517.

A Novel Missense Variant Associated with A Splicing Defect in A Myopathic Form of PGK1 Deficiency in The Spanish Population

Virginia Garcia-Solaesa, Pablo Serrano-Lorenzo, Maria Antonia Ramos-Arroyo, Alberto Blázquez, Inmaculada Pagola-Lorz, Mercè Artigas-López, Joaquín Arenas, Miguel A. Martín, Ivonne Jericó-Pascual

Genes (Basel) 2019 Oct; 10(10): 785. Published online 2019 Oct 10. doi: 10.3390/genes10100785

PMCID:: PMC6826351

Abstract Article PDF–1.5M

Select item 64411788.

PGK1 facilities cisplatin chemoresistance by triggering HSP90/ERK pathway mediated DNA repair and methylation in endometrial endometrioid adenocarcinoma

Jing-Wei Zhou, Juan-Juan Tang, Wei Sun, Hui Wang

Mol Med. 2019; 25: 11. Published online 2019 Mar 29. doi: 10.1186/s10020-019-0079-0

PMCID:: PMC6441178

Abstract Article PDF–3.0M

Select item 60406989.

The phosphoglycerate kinase 1 variants found in carcinoma cells display different catalytic activity and conformational stability compared to the native enzyme

Annarita Fiorillo, Maria Petrosino, Andrea Ilari, Alessandra Pasquo, Alessandra Cipollone, Maristella Maggi, Roberta Chiaraluce, Valerio Consalvi

PLoS One. 2018; 13(7): e0199191. Published online 2018 Jul 11. doi: 10.1371/journal.pone.0199191

PMCID:: PMC6040698

Abstract Article PDF–13M

Select item 557802010.

PGK1 Drives Hepatocellular Carcinoma Metastasis by Enhancing Metabolic Process

Huijun Xie, Guihui Tong, Yupei Zhang, Shu Liang, Kairui Tang, Qinhe Yang

Int J Mol Sci. 2017 Aug; 18(8): 1630. Published online 2017 Jul 27. doi: 10.3390/ijms18081630

PMCID:: PMC5578020

Abstract Article PDF–5.4M

Select item 488878411.

Mitochondria-translocated phosphoglycerate kinase 1 functions as a protein kinase to coordinate glycolysis and TCA cycle in tumorigenesis

Xinjian Li, Yuhui Jiang, Jill Meisenhelder, Weiwei Yang, David H. Hawke, Yanhua Zheng, Yan Xia, Kenneth Aldape, Jie He, Tony Hunter, Liwei Wang, Zhimin Lu

Mol Cell. Author manuscript; available in PMC 2016 Sep 3.

Published in final edited form as: Mol Cell. 2016 Mar 3; 61(5): 705–719. doi: 10.1016/j.molcel.2016.02.009

PMCID:: PMC4888784

Abstract Article PDF–2.7M

Select item 440245312.

Phosphoglycerate kinase-1 is a predictor of poor survival and a novel prognostic biomarker of chemoresistance to paclitaxel treatment in breast cancer

S Sun, X Liang, X Zhang, T Liu, Q Shi, Y Song, Y Jiang, H Wu, Y Jiang, X Lu, D Pang

Br J Cancer. 2015 Apr 14; 112(8): 1332–1339. Published online 2015 Mar 31. doi: 10.1038/bjc.2015.114

PMCID:: PMC4402453

Abstract Article PDF–441K

Select item 39340013.

Isolation and DNA sequence of a full-length cDNA clone for human X chromosome-encoded phosphoglycerate kinase.

A M Michelson, A F Markham, S H Orkin

Proc Natl Acad Sci U S A. 1983 Jan; 80(2): 472–476. doi: 10.1073/pnas.80.2.472

PMCID:: PMC393400

Summary Page Browse PDF–1.3M

Select item 39129014.

Structure of the human phosphoglycerate kinase gene and the intron-mediated evolution and dispersal of the nucleotide-binding domain.

A M Michelson, C C Blake, S T Evans, S H Orkin

Proc Natl Acad Sci U S A. 1985 Oct; 82(20): 6965–6969. doi: 10.1073/pnas.82.20.6965

PMCID:: PMC391290

Summary Page Browse PDF–981K

Select item 35008015.

Molecular abnormality of phosphoglycerate kinase-Uppsala associated with chronic nonspherocytic hemolytic anemia.

H Fujii, A Yoshida

Proc Natl Acad Sci U S A. 1980 Sep; 77(9): 5461–5465. doi: 10.1073/pnas.77.9.5461

PMCID:: PMC350080

Summary Page Browse PDF–1.1M

Select item 31939416.

Use of cultured lymphoblastoid cells for the study of abnormal enzymes: molecular abnormality of a phosphoglycerate kinase variant associated with hemolytic anemia.

H Fujii, S H Chen, J Akatsuka, S Miwa, A Yoshida

Proc Natl Acad Sci U S A. 1981 Apr; 78(4): 2587–2590. doi: 10.1073/pnas.78.4.2587

PMCID:: PMC319394

Summary Page Browse PDF–1.1M

Select item 4248717.

Metaphase chromosome analysis by ligation-mediated PCR: heritable chromatin structure and a comparison of active and inactive X chromosomes.

M Hershkovitz, A D Riggs

Proc Natl Acad Sci U S A. 1995 Mar 14; 92(6): 2379–2383. doi: 10.1073/pnas.92.6.2379

PMCID:: PMC42487

Summary Page Browse PDF–1.1M

Select item 1089423118.

PRMT1-mediated PGK1 arginine methylation promotes colorectal cancer glycolysis and tumorigenesis

Hao Liu, Xintian Chen, Pengfei Wang, Miaolei Chen, Chuyin Deng, Xingyou Qian, Jin Bai, Zhongwei Li, Xiangyang Yu

Cell Death Dis. 2024 Feb; 15(2): 170. Published online 2024 Feb 24. doi: 10.1038/s41419-024-06544-6

PMCID:: PMC10894231

Abstract Article PDF–4.8M

Select item 1081438819.

RNA Binding Protein PTBP1 Promotes the Metastasis of Gastric Cancer by Stabilizing PGK1 mRNA

Xiaolin Wang, Ce Liang, Shimin Wang, Qiang Ma, Xiaojuan Pan, Ai Ran, Changhong Qin, Bo Huang, Feifei Yang, Yuying Liu, Yuying Zhang, Junwu Ren, Hao Ning, Haiping Li, Yan Jiang, Bin Xiao

Cells. 2024 Jan; 13(2): 140. Published online 2024 Jan 12. doi: 10.3390/cells13020140