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Select item 100309241.

Serpin B9 controls tumor cell killing by CAR T cells

Thomas Kimman, Anne Slomp, Anne Martens, Sarah Grabherr, Shuang Li, Eline van Diest, Jan Meeldijk, Jurgen Kuball, Monique C Minnema, Eric Eldering, Niels Bovenschen, Zsolt Sebestyén, Victor Peperzak

J Immunother Cancer. 2023; 11(3): e006364. Published online 2023 Mar 17. doi: 10.1136/jitc-2022-006364

PMCID:: PMC10030924

Abstract Article PDF–3.2M

Select item 97105192.

SERPINB9 is commonly amplified and high expression in cancer cells correlates with poor immune checkpoint blockade response

Sofía Ibáñez-Molero, Alex van Vliet, Joanna Pozniak, Karlijn Hummelink, Alexandra M. Terry, Kim Monkhorst, Joyce Sanders, Ingrid Hofland, Ewout Landeloos, Yannick Van Herck, Oliver Bechter, Thomas Kuilman, Weiwei Zhong, Jean-Christophe Marine, Lodewyk Wessels, Daniel S. Peeper

Oncoimmunology. 2022; 11(1): 2139074. Published online 2022 Nov 29. doi: 10.1080/2162402X.2022.2139074

PMCID:: PMC9710519

Abstract Article PDF–4.8M

Select item 66939653.

Disrupted regulation of serpinB9 in circulating T cells is associated with an increased risk for post‐transplant skin cancer

F. S. Peters, A. M. A. Peeters, T. P. P. van den Bosch, A. L. Mooyaart, J. van de Wetering, M. G. H. Betjes, C. C. Baan, K. Boer

Clin Exp Immunol. 2019 Sep; 197(3): 341–351. Published online 2019 May 30. doi: 10.1111/cei.13309

PMCID:: PMC6693965

Abstract Article PDF–600K

Select item 59269514.

Serine Proteinase Inhibitor 9 Can Be Recognized by Cytotoxic T Lymphocytes of Epithelial Cancer Patients

Koji Tanaka, Nanae Harashima, Fumihiko Niiya, Yoshiaki Miyagi, Naoya Hida, Mika Ochi, Nobue Imai, Mamoru Harada, Kyogo Itoh, Shigeki Shichijo

Jpn J Cancer Res. 2002 Feb; 93(2): 198–208. doi: 10.1111/j.1349-7006.2002.tb01259.x

PMCID:: PMC5926951

Summary PDF–400K

Select item 44543855.

Role of protease inhibitor 9 in survival and replication of Mycobacterium tuberculosis in mononuclear phagocytes from HIV-1-infected patients

Zahra Toossi, Mianda Wu, Shigou Liu, Christina S. Hirsch, Jessica Walrath, Marieke van Ham, Richard F. Silver

AIDS. Author manuscript; available in PMC 2015 Jun 3.

Published in final edited form as: AIDS. 2014 Mar 13; 28(5): 679–687. doi: 10.1097/QAD.0000000000000192

PMCID:: PMC4454385

Abstract Article PDF–216K

Select item 25845806.

Low Concentrations of the Soy Phytoestrogen Genistein Induce Proteinase Inhibitor 9 and Block Killing of Breast Cancer Cells by Immune Cells

Xinguo Jiang, Nicole M. Patterson, Yan Ling, Jianwei Xie, William G. Helferich, David J. Shapiro

Endocrinology. 2008 Nov; 149(11): 5366–5373. Published online 2008 Jul 31. doi: 10.1210/en.2008-0857

PMCID:: PMC2584580

Abstract Article

Select item 70678617.

Telomere length correlates with subtelomeric DNA methylation in long-term mindfulness practitioners

Maite Mendioroz, Marta Puebla-Guedea, Jesús Montero-Marín, Amaya Urdánoz-Casado, Idoia Blanco-Luquin, Miren Roldán, Alberto Labarga, Javier García-Campayo

Sci Rep. 2020; 10: 4564. Published online 2020 Mar 12. doi: 10.1038/s41598-020-61241-6

PMCID:: PMC7067861

Abstract Article PDF–1.4M

Select item 34012118.

Inhibition of Granzyme B by PI-9 protects prostate cancer cells from apoptosis

Manisha Ray, Daniel R. Hostetter, Carly RK Loeb, Jeffry Simko, Charles S. Craik

Prostate. Author manuscript; available in PMC 2013 Jun 1.

Published in final edited form as: Prostate. 2012 Jun 1; 72(8): 846–855. Published online 2011 Sep 14. doi: 10.1002/pros.21486

PMCID:: PMC3401211

Abstract Article PDF–1.5M

Select item 32427439.

Induction of Serine Protease Inhibitor 9 by Mycobacterium tuberculosis Inhibits Apoptosis and Promotes Survival of Infected Macrophages

Zahra Toossi, Mianda Wu, Roxana Rojas, Barbara Kalsdorf, Htin Aung, Christina S. Hirsch, Jessica Walrath, Angela Wolbink, Marieke van Ham, Richard F. Silver

J Infect Dis. 2012 Jan 1; 205(1): 144–151. Published online 2011 Nov 16. doi: 10.1093/infdis/jir697

PMCID:: PMC3242743

Abstract Article PDF–229K

Select item 221343210.

The Serpin Proteinase Inhibitor 9 Is an Endogenous Inhibitor of Interleukin 1β–Converting Enzyme (Caspase-1) Activity in Human Vascular Smooth Muscle Cells

James L. Young, Galina K. Sukhova, Don Foster, Walter Kisiel, Peter Libby, Uwe Schönbeck

J Exp Med. 2000 May 1; 191(9): 1535–1544. doi: 10.1084/jem.191.9.1535

PMCID:: PMC2213432

Abstract Article PDF–368K

Select item 8726211.

Nucleocytoplasmic Distribution of the Ovalbumin Serpin PI-9 Requires a Nonconventional Nuclear Import Pathway and the Export Factor Crm1

Catherina H. Bird, Elizabeth J. Blink, Claire E. Hirst, Marguerite S. Buzza, Pauline M. Steele, Jiuru Sun, David A. Jans, Phillip I. Bird

Mol Cell Biol. 2001 Aug; 21(16): 5396–5407. doi: 10.1128/MCB.21.16.5396-5407.2001

PMCID:: PMC87262

Abstract Article PDF–492K

Select item 499138112.

Reduced serpinB9-mediated caspase-1 inhibition can contribute to autoinflammatory disease

Robert van der Burgh, Jan Meeldijk, Lieneke Jongeneel, Joost Frenkel, Niels Bovenschen, Mariëlle van Gijn, Marianne Boes

Oncotarget. 2016 Apr 12; 7(15): 19265–19271. Published online 2016 Mar 15. doi: 10.18632/oncotarget.8086

PMCID:: PMC4991381

Abstract Article PDF–2.3M

Select item 484022213.

Oropharyngeal squamous cell carcinomas differentially express granzyme inhibitors

Pauline M. W. van Kempen, Rob Noorlag, Justin E. Swartz, Niels Bovenschen, Weibel W. Braunius, Jeroen F. Vermeulen, Ellen M. Van Cann, Wilko Grolman, Stefan M. Willems

Cancer Immunol Immunother. 2016 May; 65(5): 575–585. Published online 2016 Mar 18. doi: 10.1007/s00262-016-1819-4