PMC Links for Gene (Select 5290) - PMC

Ali Fendri, Abdelmajid Khabir, Wafa Mnejja, Tahia Sellami‐Boudawara, Jamel Daoud, Mounir Frikha, Abdelmonem Ghorbel, Ali Gargouri, Raja Mokdad‐Gargouri

Cancer Sci. 2009 Nov; 100(11): 2034–2039. Published online 2009 Jul 21. doi: 10.1111/j.1349-7006.2009.01292.x

PMCID:: PMC11158390

Abstract Article PDF–427K

Select item 111432144.

PIK3CA mutations in endocrine-resistant breast cancer

Caroline Schagerholm, Stephanie Robertson, Hosein Toosi, Emmanouil G. Sifakis, Johan Hartman

Sci Rep. 2024; 14: 12542. Published online 2024 May 31. doi: 10.1038/s41598-024-62664-1

PMCID:: PMC11143214

Abstract Article PDF–2.4M

Select item 109278165.

PIK3CA mutation-driven immune signature as a prognostic marker for evaluating the tumor immune microenvironment and therapeutic response in breast cancer

Xueting Ren, Hanxiao Cui, Luyao Dai, Lidan Chang, Dandan Liu, Wenyu Yan, Xuyan Zhao, Huafeng Kang, Xiaobin Ma

J Cancer Res Clin Oncol. 2024; 150(3): 119. Published online 2024 Mar 11. doi: 10.1007/s00432-024-05626-4

PMCID:: PMC10927816

Abstract Article PDF–2.9M

Select item 108509446.

Allosteric PI3Kα Inhibition Overcomes On-target Resistance to Orthosteric Inhibitors Mediated by Secondary PIK3CA Mutations

Andreas Varkaris, Ferran Fece de la Cruz, Elizabeth E. Martin, Bryanna L. Norden, Nicholas Chevalier, Allison M. Kehlmann, Ignaty Leshchiner, Haley Barnes, Sara Ehnstrom, Anastasia-Maria Stavridi, Xin Yuan, Janice S. Kim, Haley Ellis, Alkistis Papatheodoridi, Hakan Gunaydin, Brian P. Danysh, Laxmi Parida, Ioannis Sanidas, Yongli Ji, Kayao Lau, Gerburg M. Wulf, Aditya Bardia, Laura M. Spring, Steven J. Isakoff, Jochen K. Lennerz, Kathryn Del Vecchio, Levi Pierce, Ermira Pazolli, Gad Getz, Ryan B. Corcoran, Dejan Juric

Cancer Discov. 2024 Feb 8; 14(2): 227–239. Published online 2023 Oct 31. doi: 10.1158/2159-8290.CD-23-0704

PMCID:: PMC10850944

Abstract Article PDF–14M

Select item 108299437.

Microcystic Lymphatic Malformations in Turner Syndrome are due to Somatic Mosaicism of PIK3CA

Bede N. Nriagu, Lydia S. Williams, Niambi Brewer, Lea F. Surrey, Abhay S. Srinivasan, Dong Li, Allison Britt, James Treat, T. Blaine Crowley, Nora O’Connor, Arupa Ganguly, David Low, Maria Queenan, Theodore G. Drivas, Elaine H. Zackai, Denise M. Adams, Hakon Hakonarson, Kristen M. Snyder, Sarah E. Sheppard

Am J Med Genet A. Author manuscript; available in PMC 2024 Jan 31.

Published in final edited form as: Am J Med Genet A. 2024 Jan; 194(1): 64–69. Published online 2023 Sep 13. doi: 10.1002/ajmg.a.63385

PMCID:: PMC10829943

Abstract Article PDF–893K

Select item 107759788.

PIK3CA regulates development of diabetes retinopathy through the PI3K/Akt/mTOR pathway

Ruijuan Guan, Zefeng Kang, Ling Li, Xin Yan, Tianpeng Gao

PLoS One. 2024; 19(1): e0295813. Published online 2024 Jan 9. doi: 10.1371/journal.pone.0295813

PMCID:: PMC10775978

Abstract Article PDF–1.9M

Select item 107338079.

Association of PIK3CA Mutation With Pathologic Complete Response and Outcome by Hormone Receptor Status and Intrinsic Subtype in Early-Stage ERBB2/HER2-Positive Breast Cancer

Paola Zagami, Aranzazu Fernandez-Martinez, Naim U. Rashid, Katherine A. Hoadley, Patricia A. Spears, Giuseppe Curigliano, Charles M. Perou, Lisa A. Carey

JAMA Netw Open. 2023 Dec; 6(12): e2348814. Published online 2023 Dec 20. doi: 10.1001/jamanetworkopen.2023.48814

PMCID:: PMC10733807

Abstract Article

Select item 1050343010.

Hemifacial myohyperplasia is due to somatic muscular PIK3CA gain-of-function mutations and responds to pharmacological inhibition

Charles Bayard, Eleonora Segna, Maxime Taverne, Antoine Fraissenon, Quentin Hennocq, Baptiste Periou, Lola Zerbib, Sophia Ladraa, Célia Chapelle, Clément Hoguin, Sophie Kaltenbach, Patrick Villarese, Vahid Asnafi, Christine Broissand, Ivan Nemazanyy, Gwennhael Autret, Nicolas Goudin, Christophe Legendre, François-Jérôme Authier, Thomas Viel, Bertrand Tavitian, Cyril Gitiaux, Sylvie Fraitag, Jean-Paul Duong, Clarisse Delcros, Bernard Sergent, Arnaud Picard, Michael Dussiot, Laurent Guibaud, Roman Khonsari, Guillaume Canaud

J Exp Med. 2023 Nov 6; 220(11): e20230926. Published online 2023 Sep 15. doi: 10.1084/jem.20230926

PMCID:: PMC10503430

Abstract Article PDF–6.4M

Select item 1036186311.

Discordance of PIK3CA mutational status between primary and metastatic breast cancer: a systematic review and meta-analysis

Justus Rosin, Ella Svegrup, Antonios Valachis, Ioannis Zerdes

Breast Cancer Res Treat. 2023; 201(2): 161–169. Published online 2023 Jul 1. doi: 10.1007/s10549-023-07010-1

PMCID:: PMC10361863

Abstract Article PDF–1.3M

Select item 1035604612.

Loss of PI3Kα Mediates Protection From Myocardial Ischemia–Reperfusion Injury Linked to Preserved Mitochondrial Function

Pavel Zhabyeyev, Brent McLean, Wesam Bassiouni, Robert Valencia, Manish Paul, Ahmed M. Darwesh, John M. Seubert, Saugata Hazra, Gavin Y. Oudit

J Am Heart Assoc. 2023 Jun 20; 12(12): e022352. Published online 2023 Jun 15. doi: 10.1161/JAHA.122.022352

PMCID:: PMC10356046

Abstract Article PDF–8.5M

Select item 1032609813.

PIK3CA mutation testing as a valuable molecular surrogate for lipomatosis of the median nerve: clinicopathological and molecular analysis of six cases

Justus Osterloh, Abbas Agaimy, Frederick Fried, Robert Stoehr, Rolf Janka, Andreas Arkudas, Raymund E. Horch

Virchows Arch. 2023; 483(1): 33–39. Published online 2023 Apr 17. doi: 10.1007/s00428-023-03540-7

PMCID:: PMC10326098

Abstract Article PDF–1.2M

Select item 1028689514.

Association between PIK3CA activating mutations and outcomes in early-stage invasive lobular breast carcinoma treated with adjuvant systemic therapy

Domen Ribnikar, Valentina Jeric Horvat, Ivica Ratosa, Zachary W Veitch, Biljana Grcar Kuzmanov, Srdjan Novakovic, Erik Langerholc, Eitan Amir, Bostjan Seruga

Radiol Oncol. 2023 Jun; 57(2): 220–228. Published online 2023 Jun 21. doi: 10.2478/raon-2023-0027

PMCID:: PMC10286895

Abstract Article PDF–518K

Select item 1023662615.

Frequent PIK3CA mutation in normal endometrial gland drives spheroid formation and may be involved in stem cell propagation

Seiya Sato, Kentaro Nakayama, Kosuke Kanno, Razia Sultana, Masako Ishikawa, Tomoka Ishibashi, Hitomi Yamashita, Satoru Kyo

Cancer Sci. 2023 Jun; 114(6): 2335–2344. Published online 2023 Mar 12. doi: 10.1111/cas.15767

PMCID:: PMC10236626

Abstract Article PDF–2.4M

Select item 1019132216.

PIK3CA mutations in breast cancer: A Tunisian series

Mariem Ben Rekaya, Farah Sassi, Essya Saied, Linda Bel Haj Kacem, Nada Mansouri, Sinda Zarrouk, Saifeddine Azouz, Soumaya Rammeh

PLoS One. 2023; 18(5): e0285413. Published online 2023 May 17. doi: 10.1371/journal.pone.0285413

PMCID:: PMC10191322

Abstract Article PDF–1.3M

Select item 1013047617.

PI3Kα Translocation Mediates Nuclear PtdIns(3,4,5)P₃ Effector Signaling in Colorectal Cancer

Michelle Palmieri, Bruno Catimel, Dmitri Mouradov, Anuratha Sakthianandeswaren, Eugene Kapp, Ching-Seng Ang, Nicholas A. Williamson, Cameron J. Nowell, Michael Christie, Jayesh Desai, Peter Gibbs, Antony W. Burgess, Oliver M. Sieber

Mol Cell Proteomics. 2023 Apr; 22(4): 100529. Published online 2023 Mar 16. doi: 10.1016/j.mcpro.2023.100529

PMCID:: PMC10130476

Abstract Article PDF–5.8M

Select item 1010179518.

PIK3CA Mutation Is Associated with Poor Response to HER2-Targeted Therapy in Breast Cancer Patients

Ju Won Kim, Ah Reum Lim, Ji Young You, Jung Hyun Lee, Sung Eun Song, Nam Kwon Lee, Seung Pil Jung, Kyu Ran Cho, Cheol Yong Kim, Kyong Hwa Park

Cancer Res Treat. 2023 Apr; 55(2): 531–541. Published online 2022 Sep 7. doi: 10.4143/crt.2022.221

PMCID:: PMC10101795

Abstract Article PDF–2.6M

Select item 1003001919.

PIK3CA mutations and their impact on survival outcomes of patients with endometrial cancer: A systematic review and meta-analysis

Hanna K. Bredin, Camilla Krakstad, Erling A. Hoivik

PLoS One. 2023; 18(3): e0283203. Published online 2023 Mar 21. doi: 10.1371/journal.pone.0283203

PMCID:: PMC10030019

Abstract Article PDF–1.4M

Select item 1001188120.

Genetic Heterogeneity and Tissue-specific Patterns of Tumors with Multiple PIK3CA Mutations

Smruthy Sivakumar, Dexter X. Jin, Ruchita Rathod, Jeffrey Ross, Lewis C. Cantley, Maurizio Scaltriti, Jessica W. Chen, Katherine E. Hutchinson, Timothy R. Wilson, Ethan S. Sokol, Neil Vasan

Clin Cancer Res. 2023 Mar 14; 29(6): 1125–1136. Published online 2023 Jan 3. doi: 10.1158/1078-0432.CCR-22-2270

PMCID:: PMC10011881

Abstract Article PDF–6.5M

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PMC Links for Gene (Select 5290) (849)
PMC
Homologene neighbors for GEO Profiles (Select 109395389) (0)
GEO Profiles
PREDICTED: Homo sapiens RNA binding motif single stranded interacting protein 2 ...
PREDICTED: Homo sapiens RNA binding motif single stranded interacting protein 2 (RBMS2), transcript variant X5, mRNA
gi|2462533541|ref|XM_054372813.1|

Nucleotide
MULTISPECIES: glutamate-1-semialdehyde 2,1-aminomutase [unclassified Erwinia]
MULTISPECIES: glutamate-1-semialdehyde 2,1-aminomutase [unclassified Erwinia]
gi|1275613556|ref|WP_099706475.1|

Protein

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