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Select item 108891671.

uPAR (PLAUR) Marks Two Intra-Tumoral Subtypes of Glioblastoma: Insights from Single-Cell RNA Sequencing

Yue He, Kristina B. V. Døssing, Maria Rossing, Frederik Otzen Bagger, Andreas Kjaer

Int J Mol Sci. 2024 Feb; 25(4): 1998. Published online 2024 Feb 7. doi: 10.3390/ijms25041998

PMCID:: PMC10889167

Abstract Article PDF–2.1M

Select item 108111502.

Soluble urokinase plasminogen activator receptor (suPAR) in bronchoalveolar fluid and blood in critically ill patients—a prospective cohort study

Alexander C. Reisinger, Stefan Hatzl, Juergen Prattes, Gerald Hackl, Gernot Schilcher, Florian Eisner, Tobias Niedrist, Reinhard Raggam, Robert Krause, Philipp Eller

Infection. 2024; 52(1): 249–252. Published online 2023 Nov 16. doi: 10.1007/s15010-023-02127-3

PMCID:: PMC10811150

Abstract Article PDF–645K

Select item 107825243.

Soluble urokinase plasminogen activator receptor in vaginally collected amniotic fluid predicting fetal inflammatory response syndrome: a prospective cohort study

Violeta Gulbiniene, Irena Dumalakiene, Greta Balciuniene, Ingrida Pilypiene, Ieva Narkeviciute, Vitalij Novickij, Gintautas Vysniauskis, Diana Ramasauskaite

BMC Pregnancy Childbirth. 2024; 24: 54. Published online 2024 Jan 10. doi: 10.1186/s12884-023-06221-0

PMCID:: PMC10782524

Abstract Article PDF–1.2M

Select item 101384064.

Circulating Soluble Urokinase Plasminogen Activator Receptor as a Predictive Indicator for COVID-19-Associated Acute Kidney Injury and Mortality: Clinical and Bioinformatics Analysis

Hidi A. A. Abdellatif, Basma Osman Sultan, Hassnaa M. Nassar, Mostafa Elsaied Elsayed Gomaa, Mohamed Gamal Sakr, Eman Riad, Alhanouf I. Al-Harbi, Jawaher A. Abdulhakim, Manal S. Fawzy, Noha M. Abd El-Fadeal

Int J Mol Sci. 2023 Apr; 24(8): 7177. Published online 2023 Apr 13. doi: 10.3390/ijms24087177

PMCID:: PMC10138406

Abstract Article PDF–14M

Select item 99340695.

Urokinase plasminogen activator surface receptor restricts HIV-1 replication by blocking virion release from the cell membrane

Hailin Pang, Jiayue Ouyang, Zengwen Yang, Hong Shang, Guoxin Liang

Proc Natl Acad Sci U S A. 2023 Jan 17; 120(3): e2212991120. Published online 2023 Jan 13. doi: 10.1073/pnas.2212991120

PMCID:: PMC9934069

Abstract Article PDF–1.8M

Select item 97851756.

The Association of PLAUR Genotype and Soluble suPAR Serum Level with COVID-19-Related Lung Damage Severity

Ludmila A. Nekrasova, Anna A. Shmakova, Larisa M. Samokhodskaya, Karina I. Kirillova, Simona S. Stoyanova, Elena A. Mershina, Galina B. Nazarova, Kseniya A. Rubina, Ekaterina V. Semina, Armais A. Kamalov

Int J Mol Sci. 2022 Dec; 23(24): 16210. Published online 2022 Dec 19. doi: 10.3390/ijms232416210

PMCID:: PMC9785175

Abstract Article PDF–1.4M

Select item 97540007.

Increased soluble urokinase plasminogen activator levels modulate monocyte function to promote atherosclerosis

George Hindy, Daniel J. Tyrrell, Alexi Vasbinder, Changli Wei, Feriel Presswalla, Hui Wang, Pennelope Blakely, Ayse Bilge Ozel, Sarah Graham, Grace H. Holton, Joseph Dowsett, Akl C. Fahed, Kingsley-Michael Amadi, Grace K. Erne, Annika Tekmulla, Anis Ismail, Christopher Launius, Nona Sotoodehnia, James S. Pankow, Lise Wegner Thørner, Christian Erikstrup, Ole Birger Pedersen, Karina Banasik, Søren Brunak, Henrik Ullum, Jesper Eugen-Olsen, Sisse Rye Ostrowski, on behalf of the DBDS Consortium, Mary E. Haas, Jonas B. Nielsen, Luca A. Lotta, on behalf of the Regeneron Genetics Center, Gunnar Engström, Olle Melander, Marju Orho-Melander, Lili Zhao, Venkatesh L. Murthy, David J. Pinsky, Cristen J. Willer, Susan R. Heckbert, Jochen Reiser, Daniel R. Goldstein, Karl C. Desch, Salim S. Hayek

J Clin Invest. 2022 Dec 15; 132(24): e158788. Published online 2022 Dec 15. doi: 10.1172/JCI158788

PMCID:: PMC9754000

Abstract Article PDF–1.4M

Select item 92146418.

Soluble urokinase-type plasminogen activator receptor and incident end-stage renal disease in Chinese patients with chronic kidney disease

Li Lv, Fang Wang, Liang Wu, Jin-Wei Wang, Zhao Cui, Salim S Hayek, Changli Wei, Jochen Reiser, Kevin He, Luxia Zhang, Min Chen, Ming-Hui Zhao

Nephrol Dial Transplant. 2020 Mar; 35(3): 465–470. Published online 2018 Aug 13. doi: 10.1093/ndt/gfy265

PMCID:: PMC9214641

Abstract Article PDF–141K

Select item 91768309.

Comprehensive analysis of the importance of PLAUR in the progression and immune microenvironment of renal clear cell carcinoma

Zhiwei Wang, Kunxiong Wang, Xin Gao, Zhenxiang Liu, Zengshu Xing

PLoS One. 2022; 17(6): e0269595. Published online 2022 Jun 8. doi: 10.1371/journal.pone.0269595

PMCID:: PMC9176830

Abstract Article PDF–3.2M

Select item 879063710.

Poder pronóstico de mortalidad a corto plazo del receptor soluble activador del plasminógeno tipo uroquinasa (suPAR) en los pacientes atendidos en urgencias por infección

Rafael Rubio Díaz, Elena de Rafael González, Esther Martín Torres, Elena Valera Núñez, Aurora María López Martos, David Melguizo Melguizo, María Piedad Picazo Perea, Pedro Jesús López García, Patricia Fuentes Bullejos, Matilde Chafer Rudilla, Julián Fabián Carretero Gómez, María Carmen Lorenzo Lozano, Agustín Julián-Jiménez

Rev Esp Quimioter. 2022; 35(1): 50–62. Spanish. Published online 2021 Dec 3. doi: 10.37201/req/108.2021

PMCID:: PMC8790637

Abstract Article PDF–602K

Select item 869238911.

Soluble Urokinase Plasminogen Activator Receptor: Genetic Variation and Cardiovascular Disease Risk in African Americans: Olson; suPAR genetic variation and CVD risk in JHS

Nels C. Olson, Laura M. Raffield, Anne H. Moxley, Tyne W. Miller-Fleming, Paul L. Auer, Nora Franceschini, Debby Ngo, Timothy A. Thornton, Ethan M. Lange, Yun Li, Deborah A. Nickerson, Neil A. Zakai, Robert E. Gerszten, Nancy J. Cox, Adolfo Correa, Karen L. Mohlke, Alex P. Reiner

Circ Genom Precis Med. Author manuscript; available in PMC 2022 Dec 1.

Published in final edited form as: Circ Genom Precis Med. 2021 Dec; 14(6): e003421. Published online 2021 Oct 28. doi: 10.1161/CIRCGEN.121.003421

PMCID:: PMC8692389

Abstract Article PDF–439K

Select item 858140612.

Plasma Gradient of Soluble Urokinase-Type Plasminogen Activator Receptor Is Linked to Pathogenic Plasma Proteome and Immune Transcriptome and Stratifies Outcomes in Severe COVID-19

Jafar Sarif, Deblina Raychaudhuri, Ranit D’Rozario, Purbita Bandopadhyay, Praveen Singh, Priyanka Mehta, Md. Asmaul Hoque, Bishnu Prasad Sinha, Manoj Kushwaha, Shweta Sahni, Priti Devi, Partha Chattopadhyay, Shekhar Ranjan Paul, Yogiraj Ray, Kausik Chaudhuri, Sayantan Banerjee, Debajyoti Majumdar, Bibhuti Saha, Biswanath Sharma Sarkar, Prasun Bhattacharya, Shilpak Chatterjee, Sandip Paul, Pramit Ghosh, Rajesh Pandey, Shantanu Sengupta, Dipyaman Ganguly

Front Immunol. 2021; 12: 738093. Published online 2021 Oct 28. doi: 10.3389/fimmu.2021.738093

PMCID:: PMC8581406

Abstract Article PDF–5.3M

Select item 834259313.

Plasminogen Activator Urokinase Receptor Implies Immunosuppressive Features and Acts as an Unfavorable Prognostic Biomarker in Glioma

Fan Zeng, Guanzhang Li, Xiu Liu, Kenan Zhang, Hua Huang, Tao Jiang, Ying Zhang

Oncologist. 2021 Aug; 26(8): e1460–e1469. Published online 2021 Mar 28. doi: 10.1002/onco.13750

PMCID:: PMC8342593

Abstract Article PDF–5.7M

Select item 817292814.

Eleven genomic loci affect plasma levels of chronic inflammation marker soluble urokinase-type plasminogen activator receptor

Joseph Dowsett, Egil Ferkingstad, Line Jee Hartmann Rasmussen, Lise Wegner Thørner, Magnús K. Magnússon, Karen Sugden, Gudmar Thorleifsson, Mike Frigge, Kristoffer Sølvsten Burgdorf, Sisse Rye Ostrowski, Erik Sørensen, Christian Erikstrup, Ole Birger Pedersen, Thomas Folkmann Hansen, Karina Banasik, Søren Brunak, DBDS Genomic Consortium, Vinicius Tragante, Sigrun Helga Lund, Lilja Stefansdottir, Bjarni Gunnarson, Richie Poulton, Louise Arseneault, Avshalom Caspi, Terrie E. Moffitt, Daníel Gudbjartsson, Jesper Eugen-Olsen, Hreinn Stefánsson, Kári Stefánsson, Henrik Ullum

Commun Biol. 2021; 4: 655. Published online 2021 Jun 2. doi: 10.1038/s42003-021-02144-8

PMCID:: PMC8172928

Abstract Article PDF–1.3M

Select item 811242015.

uPAR⁺ extracellular vesicles: a robust biomarker of resistance to checkpoint inhibitor immunotherapy in metastatic melanoma patients

Letizia Porcelli, Michele Guida, Simona De Summa, Roberta Di Fonte, Ivana De Risi, Marianna Garofoli, Mariapia Caputo, Antonio Negri, Sabino Strippoli, Simona Serratì, Amalia Azzariti

J Immunother Cancer. 2021; 9(5): e002372. Published online 2021 May 10. doi: 10.1136/jitc-2021-002372

PMCID:: PMC8112420

Abstract Article PDF–1.9M

Select item 800449716.

uPAR-expressing melanoma exosomes promote angiogenesis by VE-Cadherin, EGFR and uPAR overexpression and rise of ERK1,2 signaling in endothelial cells

Alessio Biagioni, Anna Laurenzana, Beatrice Menicacci, Silvia Peppicelli, Elena Andreucci, Francesca Bianchini, Daniele Guasti, Paolo Paoli, Simona Serratì, Alessandra Mocali, Lido Calorini, Mario Del Rosso, Gabriella Fibbi, Anastasia Chillà, Francesca Margheri

Cell Mol Life Sci. 2021 Mar; 78(6): 3057–3072. Published online 2020 Nov 25. doi: 10.1007/s00018-020-03707-4

PMCID:: PMC8004497

Abstract Article PDF–3.0M

Select item 799740617.

Soluble Urokinase Plasminogen Activator Receptor as a Decision Marker for Early Discharge of Patients with COVID-19 Symptoms in the Emergency Department

Marius Ahm Stauning, Izzet Altintas, Thomas Kallemose, Jesper Eugen-Olsen, Mette Bendtz Lindstrøm, Line Jee Hartmann Rasmussen, Hejdi Gamst-Jensen, Jan O. Nehlin, Ove Andersen, Jens Tingleff

J Emerg Med. 2021 Sep; 61(3): 298–313. Published online 2021 Mar 26. doi: 10.1016/j.jemermed.2021.03.012

PMCID:: PMC7997406

Abstract Article PDF–1.0M

Select item 788099318.

Soluble urokinase-type plasminogen activator receptor (suPAR) is a risk indicator for eGFR loss in kidney transplant recipients

Ulrich Jehn, Katharina Schütte-Nütgen, Ute Henke, Hermann Pavenstädt, Barbara Suwelack, Stefan Reuter

Sci Rep. 2021; 11: 3713. Published online 2021 Feb 12. doi: 10.1038/s41598-021-83333-7

PMCID:: PMC7880993

Abstract Article PDF–1.0M

Select item 742854219.

Cardio‐Renal Biomarker Soluble Urokinase‐Type Plasminogen Activator Receptor Is Associated With Cardiovascular Death and Myocardial Infarction in Patients With Coronary Artery Disease Independent of Troponin, C‐Reactive Protein, and Renal Function

Julius Nikorowitsch, Tim Borchardt, Sebastian Appelbaum, Francisco Ojeda, Karl J. Lackner, Renate B. Schnabel, Stefan Blankenberg, Tanja Zeller, Mahir Karakas

J Am Heart Assoc. 2020 Apr 21; 9(8): e015452. Published online 2020 Apr 17. doi: 10.1161/JAHA.119.015452

PMCID:: PMC7428542

Abstract Article PDF–342K

Select item 742851920.

Soluble Urokinase‐Type Plasminogen Activator Receptor and High‐Sensitivity Troponin Levels Predict Outcomes in Nonobstructive Coronary Artery Disease

Ahmed Al‐Badri, Ayman Samman Tahhan, Nabil Sabbak, Ayman Alkhoder, Chang Liu, Yi‐An Ko, Viola Vaccarino, Afif Martini, Arianna Sidoti, Cydney Goodwin, Bahjat Ghazzal, Agim Beshiri, Gillian Murtagh, Puja K. Mehta, Arshed A. Quyyumi

J Am Heart Assoc. 2020 Apr 21; 9(8): e015515. Published online 2020 Apr 17. doi: 10.1161/JAHA.119.015515

PMCID:: PMC7428519

Abstract Article PDF–781K

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