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Select item 109299311.

与家族性系统性红斑狼疮有关的PLD2基因新突变及其功能分析

彭琳, 袁新科, 陈李笑, 陈斯佳, 陈科

Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2021 Mar 28; 46(3): 234–239. Chinese. doi: 10.11817/j.issn.1672-7347.2021.190589

PMCID:: PMC10929931

Abstract Article PDF–1.0M

Select item 108958522.

Essential role of PLD2 in hypoxia-induced stemness and therapy resistance in ovarian tumors

Sandra Muñoz-Galván, Eva M. Verdugo-Sivianes, José M. Santos-Pereira, Purificación Estevez-García, Amancio Carnero

J Exp Clin Cancer Res. 2024; 43: 57. Published online 2024 Feb 26. doi: 10.1186/s13046-024-02988-y

PMCID:: PMC10895852

Abstract Article PDF–9.6M

Select item 73711633.

PLD2–PI(4,5)P2 interactions in fluid phase membranes: Structural modeling and molecular dynamics simulations

Kyungreem Han, Richard W. Pastor, Cristina Fenollar–Ferrer

PLoS One. 2020; 15(7): e0236201. Published online 2020 Jul 20. doi: 10.1371/journal.pone.0236201

PMCID:: PMC7371163

Abstract Article PDF–5.1M

Select item 69646974.

Phospholipase D2 in prostate cancer: protein expression changes with Gleason score

Amanda R. Noble, Karen Hogg, Rakesh Suman, Daniel M. Berney, Sylvain Bourgoin, Norman J. Maitland, Martin G. Rumsby

Br J Cancer. 2019 Dec 10; 121(12): 1016–1026. Published online 2019 Nov 1. doi: 10.1038/s41416-019-0610-7

PMCID:: PMC6964697

Abstract Article PDF–3.0M

Select item 45393775.

Phosphatidic Acid Increases Epidermal Growth Factor Receptor Expression by Stabilizing mRNA Decay and by Inhibiting Lysosomal and Proteasomal Degradation of the Internalized Receptor

Nathaniel Hatton, Erin Lintz, Madhu Mahankali, Karen M. Henkels, Julian Gomez-Cambronero

Mol Cell Biol. 2015 Sep; 35(18): 3131–3144. Prepublished online 2015 Jun 29. Published online 2015 Aug 17. doi: 10.1128/MCB.00286-15

PMCID:: PMC4539377

Abstract Article PDF–4.2M

Select item 43143466.

Mechanism of Enzymatic Reaction and Protein-Protein Interactions of PLD from a 3D Structural Model

Madhu Mahankali, Gerald Alter, Julian Gomez-Cambronero

Cell Signal. Author manuscript; available in PMC 2016 Jan 1.

Published in final edited form as: Cell Signal. 2015 Jan; 27(1): 69–81. Published online 2014 Oct 12. doi: 10.1016/j.cellsig.2014.09.008

PMCID:: PMC4314346

Abstract Article PDF–1.6M

Select item 42743957.

Inhibition of phospholipase D2 induces autophagy in colorectal cancer cells

Won Chan Hwang, Mi Kyoung Kim, Ju Hyun Song, Kang-Yell Choi, Do Sik Min

Exp Mol Med. 2014 Dec; 46(12): e124. Published online 2014 Dec 5. doi: 10.1038/emm.2014.74

PMCID:: PMC4274395

Abstract Article PDF–2.5M

Select item 42130618.

Phospholipase D2 Is Involved in the Formation of Golgi Tubules and ArfGAP1 Recruitment

Narcisa Martínez-Martínez, Emma Martínez-Alonso, José Ballesta, José A. Martínez-Menárguez

PLoS One. 2014; 9(10): e111685. Published online 2014 Oct 29. doi: 10.1371/journal.pone.0111685

PMCID:: PMC4213061

Abstract Article PDF–15M

Select item 41621469.

Phospholipase D Facilitates Efficient Entry of Influenza Virus, Allowing Escape from Innate Immune Inhibition

Thomas H. Oguin, III, Shalini Sharma, Amanda D. Stuart, Susu Duan, Sarah A. Scott, Carrie K. Jones, J. Scott Daniels, Craig W. Lindsley, Paul G. Thomas, H. Alex Brown

J Biol Chem. 2014 Sep 12; 289(37): 25405–25417. Published online 2014 Jul 27. doi: 10.1074/jbc.M114.558817

PMCID:: PMC4162146

Abstract Article PDF–2.7M

Select item 413276310.

Phospholipase D in Cell Signaling: From a Myriad of Cell Functions to Cancer Growth and Metastasis

Julian Gomez-Cambronero

J Biol Chem. 2014 Aug 15; 289(33): 22557–22566. Published online 2014 Jul 2. doi: 10.1074/jbc.R114.574152

PMCID:: PMC4132763

Abstract Article PDF–1.8M

Select item 396665111.

PHOSPHOLIPASE D (PLD) DRIVES CELL INVASION, TUMOR GROWTH AND METASTASIS IN A HUMAN BREAST CANCER XENOGRAPH MODEL

Karen M. Henkels, Gregory P. Boivin, Emily S. Dudley, Steven J. Berberich, Julian Gomez-Cambronero

Oncogene. Author manuscript; available in PMC 2014 Jun 5.

Published in final edited form as: Oncogene. 2013 Dec 5; 32(49): 5551–5562. Published online 2013 Jun 10. doi: 10.1038/onc.2013.207

PMCID:: PMC3966651

Abstract Article PDF–3.5M

Select item 324909112.

Phospholipase D2 (PLD2) Shortens the Time Required for Myeloid Leukemic Cell Differentiation: MECHANISM OF ACTION

Mauricio Di Fulvio, Kathleen Frondorf, Karen M. Henkels, William C. Grunwald, Jr., David Cool, Julian Gomez-Cambronero

J Biol Chem. 2012 Jan 2; 287(1): 393–407. Published online 2011 Nov 17. doi: 10.1074/jbc.M111.259465

PMCID:: PMC3249091

Abstract Article PDF–2.6M

Select item 307339613.

THE UNCOVERING OF A NOVEL REGULATORY MECHANISM FOR PLD2: FORMATION OF A TERNARY COMPLEX WITH PROTEIN TYROSINE PHOSPHATASE PTP1B AND GROWTH FACTOR RECEPTOR-BOUND PROTEIN GRB2

Jeff Horn, Isabel Lopez, Mill Miller, Julian Gomez-Cambronero

Biochem Biophys Res Commun. Author manuscript; available in PMC 2011 Apr 11.

Published in final edited form as: Biochem Biophys Res Commun. 2005 Jun 24; 332(1): 58–67. doi: 10.1016/j.bbrc.2005.04.093

PMCID:: PMC3073396

Abstract Article PDF–518K

Select item 286358914.

A Comprehensive Model That Explains the Regulation of Phospholipase D2 Activity by Phosphorylation-Dephosphorylation

Karen M. Henkels, Hong-Juan Peng, Kathleen Frondorf, Julian Gomez-Cambronero

Mol Cell Biol. 2010 May; 30(9): 2251–2263. Published online 2010 Feb 22. doi: 10.1128/MCB.01239-09

PMCID:: PMC2863589

Abstract Article PDF–2.2M

Select item 122308615.

Endogenous phospholipase D2 localizes to the plasma membrane of RBL-2H3 mast cells and can be distinguished from ADP ribosylation factor-stimulated phospholipase D1 activity by its specific sensitivity to oleic acid.

Elisabeth Sarri, Raul Pardo, Amanda Fensome-Green, Shamshad Cockcroft

Biochem J. 2003 Jan 15; 369(Pt 2): 319–329. doi: 10.1042/BJ20021347

PMCID:: PMC1223086

Summary PDF–426K

Select item 106959016.

Novel Functions of the Phospholipase D2-Phox Homology Domain in Protein Kinase Cζ Activation

Jong Hyun Kim, Jung Hwan Kim, Motoi Ohba, Pann-Ghill Suh, Sung Ho Ryu

Mol Cell Biol. 2005 Apr; 25(8): 3194–3208. doi: 10.1128/MCB.25.8.3194-3208.2005

PMCID:: PMC1069590

Abstract Article PDF–963K

Select item 972465817.

Parkin coordinates mitochondrial lipid remodeling to execute mitophagy

Chao‐Chieh Lin, Jin Yan, Meghan D Kapur, Kristi L Norris, Cheng‐Wei Hsieh, De Huang, Nicolas Vitale, Kah‐Leong Lim, Ziqiang Guan, Xiao‐Fan Wang, Jen‐Tsan Chi, Wei‐Yuan Yang, Tso‐Pang Yao

EMBO Rep. 2022 Dec; 23(12): e55191. Published online 2022 Oct 18. doi: 10.15252/embr.202255191

PMCID:: PMC9724658

Abstract Article PDF–8.7M

Select item 965887118.

Exosome Secretion and Epithelial-Mesenchymal Transition in Ovarian Cancer Are Regulated by Phospholipase D

Hadil Onallah, Sheethal Thomas Mannully, Ben Davidson, Reuven Reich

Int J Mol Sci. 2022 Nov; 23(21): 13286. Published online 2022 Oct 31. doi: 10.3390/ijms232113286

PMCID:: PMC9658871

Abstract Article PDF–2.6M

Select item 819364119.

Structure and Regulation of Human Phospholipase D

Forrest Z. Bowling, Michael A. Frohman, Michael V. Airola

Adv Biol Regul. Author manuscript; available in PMC 2022 Jan 3.

Published in final edited form as: Adv Biol Regul. 2021 Jan; 79: 100783. Published online 2021 Jan 3. doi: 10.1016/j.jbior.2020.100783

PMCID:: PMC8193641

Abstract Article PDF–1.3M

Select item 598987720.

Phospholipase D2 promotes disease progression of renal cell carcinoma through the induction of angiogenin

Shuya Kandori, Takahiro Kojima, Taeko Matsuoka, Takayuki Yoshino, Aiko Sugiyama, Eijiro Nakamura, Toru Shimazui, Yuji Funakoshi, Yasunori Kanaho, Hiroyuki Nishiyama

Cancer Sci. 2018 Jun; 109(6): 1865–1875. Published online 2018 May 25. doi: 10.1111/cas.13609

PMCID:: PMC5989877

Abstract Article PDF–1.4M

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PMC Links for Gene (Select 5338) (93)
PMC
Aeromonas hydrophila strain SHSK47 chromosome, complete genome
Aeromonas hydrophila strain SHSK47 chromosome, complete genome
gi|2734864018|gb|CP113533.1|

Nucleotide
CAND2[gene] (142)
ClinVar
PREDICTED: Homo sapiens X-ray repair cross complementing 4 (XRCC4), transcript v...
PREDICTED: Homo sapiens X-ray repair cross complementing 4 (XRCC4), transcript variant X7, mRNA
gi|2462604266|ref|XM_054353435.1|

Nucleotide
PREDICTED: Homo sapiens X-ray repair cross complementing 4 (XRCC4), transcript v...
PREDICTED: Homo sapiens X-ray repair cross complementing 4 (XRCC4), transcript variant X5, mRNA
gi|2462604262|ref|XM_054353433.1|

Nucleotide

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