PMC Links for Gene (Select 5406) - PMC

Select item 66248451.

Protease-sensitive pancreatic lipase (PNLIP) variants are associated with early onset chronic pancreatitis

Denise Lasher, András Szabó, Atsushi Masamune, Jian-Min Chen, Xunjun Xiao, David C. Whitcomb, M. Michael Barmada, Maren Ewers, Claudia Ruffert, Sumit Paliwal, Prachand Issarapu, Seema Bhaskar, K Radha Mani, Giriraj R Chandak, Helmut Laumen, Emmanuelle Masson, Kiyoshi Kume, Shin Hamada, Eriko Nakano, Katharina Seltsam, Peter Bugert, Thomas Müller, David A. Groneberg, Tooru Shimosegawa, Jonas Rosendahl, Claude Férec, Mark E. Lowe, Heiko Witt, Miklós Sahin-Tóth

Am J Gastroenterol. Author manuscript; available in PMC 2019 Jul 12.

Published in final edited form as: Am J Gastroenterol. 2019 Jun; 114(6): 974–983. doi: 10.14309/ajg.0000000000000051

PMCID:: PMC6624845

Abstract Article PDF–936K

Select item 49394932.

Clinical efficacy of serum lipase subtype analysis for the differential diagnosis of pancreatic and non-pancreatic lipase elevation

Chang Seok Bang, Jin Bong Kim, Sang Hyun Park, Gwang Ho Baik, Ki Tae Su, Jai Hoon Yoon, Yeon Soo Kim, Dong Joon Kim

Korean J Intern Med. 2016 Jul; 31(4): 660–668. Published online 2016 Jun 1. doi: 10.3904/kjim.2015.007

PMCID:: PMC4939493

Abstract Article PDF–332K

Select item 44092823.

A broad pH range indicator-based spectrophotometric assay for true lipases using tributyrin and tricaprylin

María de los Angeles Camacho-Ruiz, Juan Carlos Mateos-Díaz, Frédéric Carrière, Jorge A. Rodriguez

J Lipid Res. 2015 May; 56(5): 1057–1067. doi: 10.1194/jlr.D052837

PMCID:: PMC4409282

Abstract Article PDF–613K

Select item 36953954.

Val-407 and Ile-408 in the β5′-Loop of Pancreatic Lipase Mediate Lipase-Colipase Interactions in the Presence of Bile Salt Micelles

Angela Bourbon Freie, Francine Ferrato, Frédéric Carrière, Mark E. Lowe

J Biol Chem. Author manuscript; available in PMC 2013 Jun 28.

Published in final edited form as: J Biol Chem. 2006 Mar 24; 281(12): 7793–7800. Published online 2006 Jan 23. doi: 10.1074/jbc.M512984200

PMCID:: PMC3695395

Abstract Article PDF–2.0M

Select item 33949515.

Glycomic and Proteomic Profiling of Pancreatic Cyst Fluids Identifies Hyperfucosylated Lactosamines on the N-linked Glycans of Overexpressed Glycoproteins

Benjamin F. Mann, John A. Goetz, Michael G. House, C. Max Schmidt, Milos V. Novotny

Mol Cell Proteomics. 2012 Jul; 11(7): M111.015792. Published online 2012 Mar 5. doi: 10.1074/mcp.M111.015792

PMCID:: PMC3394951

Abstract Article PDF–1.2M

Select item 26828646.

Trp-107 and Trp-253 Account for the Increased Steady State Fluorescence That Accompanies the Conformational Change in Human Pancreatic Triglyceride Lipase Induced by Tetrahydrolipstatin and Bile Salt

Angela Bourbon-Freie, Rachel E. Dub, Xunjun Xiao, Mark E. Lowe

J Biol Chem. 2009 May 22; 284(21): 14157–14164. doi: 10.1074/jbc.M901154200

PMCID:: PMC2682864

Abstract Article PDF–339K

Select item 46452787.

A novel mutation in PNLIP causes pancreatic triglyceride lipase deficiency through protein misfolding

András Szabó, Xunjun Xiao, Margaret Haughney, Alyssa Spector, Miklós Sahin-Tóth, Mark E. Lowe

Biochim Biophys Acta. Author manuscript; available in PMC 2016 Jul 1.

Published in final edited form as: Biochim Biophys Acta. 2015 Jul; 1852(7): 1372–1379. Published online 2015 Apr 7. doi: 10.1016/j.bbadis.2015.04.002

PMCID:: PMC4645278

Abstract Article PDF–637K

Select item 38866698.

Identification of a novel mutation in the PNLIP gene in two brothers with congenital pancreatic lipase deficiency

Doron M. Behar, Lina Basel-Vanagaite, Fabian Glaser, Marielle Kaplan, Shay Tzur, Nurit Magal, Tal Eidlitz-Markus, Yishay Haimi-Cohen, Galit Sarig, Concetta Bormans, Mordechai Shohat, Avraham Zeharia

J Lipid Res. 2014 Feb; 55(2): 307–312. doi: 10.1194/jlr.P041103

PMCID:: PMC3886669

Abstract Article PDF–761K

Select item 37780779.

Integration of Metabolomics and Transcriptomics Revealed a Fatty Acid Network Exerting Growth Inhibitory Effects in Human Pancreatic Cancer

Geng Zhang, Peijun He, Hanson Tan, Anuradha Budhu, Jochen Gaedcke, B. Michael Ghadimi, Thomas Ried, Harris G. Yfantis, Dong H. Lee, Anirban Maitra, Nader Hanna, H. Richard Alexander, S. Perwez Hussain

Clin Cancer Res. Author manuscript; available in PMC 2014 Sep 15.

Published in final edited form as: Clin Cancer Res. 2013 Sep 15; 19(18): 4983–4993. Published online 2013 Aug 5. doi: 10.1158/1078-0432.CCR-13-0209

PMCID:: PMC3778077

Abstract Article PDF–2.2M

Select item 710891810.

Pancreatic triglyceride lipase mediates lipotoxic systemic inflammation

Cristiane de Oliveira, Biswajit Khatua, Pawan Noel, Sergiy Kostenko, Arup Bag, Bijinu Balakrishnan, Krutika S. Patel, Andre A. Guerra, Melissa N. Martinez, Shubham Trivedi, Ann McCullough, Dora M. Lam-Himlin, Sarah Navina, Douglas O. Faigel, Norio Fukami, Rahul Pannala, Anna Evans Phillips, Georgios I. Papachristou, Erin E. Kershaw, Mark E. Lowe, Vijay P. Singh

J Clin Invest. 2020 Apr 1; 130(4): 1931–1947. Published online 2020 Mar 9. doi: 10.1172/JCI132767

PMCID:: PMC7108918

Abstract Article PDF–25M

Select item 390501411.

Genome-Wide Association Study of Proneness to Anger

Eric Mick, James McGough, Curtis K. Deutsch, Jean A. Frazier, David Kennedy, Robert J. Goldberg

PLoS One. 2014; 9(1): e87257. Published online 2014 Jan 28. doi: 10.1371/journal.pone.0087257

PMCID:: PMC3905014

Abstract Article PDF–243K

Select item 138022512.

A Scan of Chromosome 10 Identifies a Novel Locus Showing Strong Association with Late-Onset Alzheimer Disease

Andrew Grupe, Yonghong Li, Charles Rowland, Petra Nowotny, Anthony L. Hinrichs, Scott Smemo, John S. K. Kauwe, Taylor J. Maxwell, Sara Cherny, Lisa Doil, Kristina Tacey, Ryan van Luchene, Amanda Myers, Fabienne Wavrant-De Vrièze, Mona Kaleem, Paul Hollingworth, Luke Jehu, Catherine Foy, Nicola Archer, Gillian Hamilton, Peter Holmans, Chris M. Morris, Joseph Catanese, John Sninsky, Thomas J. White, John Powell, John Hardy, Michael O’Donovan, Simon Lovestone, Lesley Jones, John C. Morris, Leon Thal, Michael Owen, Julie Williams, Alison Goate

Am J Hum Genet. 2006 Jan; 78(1): 78–88. Published online 2005 Nov 15. doi: 10.1086/498851

PMCID:: PMC1380225

Abstract Article PDF–329K

Select item 296748913.

A Human MAP Kinase Interactome

Sourav Bandyopadhyay, Chih-yuan Chiang, Jyoti Srivastava, Merril Gersten, Suhaila White, Russell Bell, Cornelia Kurschner, Christopher H. Martin, Mike Smoot, Sudhir Sahasrabudhe, Diane L. Barber, Sumit K. Chanda, Trey Ideker

Nat Methods. Author manuscript; available in PMC 2011 Apr 1.

Published in final edited form as: Nat Methods. 2010 Oct; 7(10): 801–805. doi: 10.1038/nmeth.1506

PMCID:: PMC2967489

Abstract Article PDF–1.2M

Select item 553161114.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 816503015.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011