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Select item 108077141.

MIG6 loss confers resistance to ALK/ROS1 inhibitors in NSCLC through EGFR activation by low-dose EGF

Nobuyuki Kondo, Takahiro Utsumi, Yuki Shimizu, Ai Takemoto, Tomoko Oh-hara, Ken Uchibori, Sophia Subat-Motoshi, Hironori Ninomiya, Kengo Takeuchi, Makoto Nishio, Yasunari Miyazaki, Ryohei Katayama

JCI Insight. 2023 Dec 22; 8(24): e173688. Published online 2023 Dec 22. doi: 10.1172/jci.insight.173688

PMCID:: PMC10807714

Abstract Article PDF–3.4M

Select item 97387202.

MIG-6 Is Critical for Progesterone Responsiveness in Human Complex Atypical Hyperplasia and Early-Stage Endometrial Cancer

Olivia Jeong, Russell R. Broaddus, Bruce A. Lessey, John I. Risinger, Mark I. Hunter, Tae Hoon Kim

Int J Mol Sci. 2022 Dec; 23(23): 14596. Published online 2022 Nov 23. doi: 10.3390/ijms232314596

PMCID:: PMC9738720

Abstract Article PDF–7.6M

Select item 87206213.

Mig‐6 could inhibit cell proliferation and induce apoptosis in esophageal squamous cell carcinoma

Yuantao Cui, Ying Kang, Peng Zhang, Yuanguo Wang, Zhaoyu Yang, Chao Lu, Peng Zhang

Thorac Cancer. 2022 Jan; 13(1): 54–60. Published online 2021 Nov 30. doi: 10.1111/1759-7714.14223

PMCID:: PMC8720621

Abstract Article PDF–1.3M

Select item 73163684.

Differential Glucocorticoid-Dependent Regulation and Function of the ERRFI1 Gene in Triple-Negative Breast Cancer

Chromewell Agustin R Mojica, Weand S Ybañez, Kevin Christian V Olarte, Alyssa Beatrice C Poblete, Pia D Bagamasbad

Endocrinology. 2020 Jul; 161(7): bqaa082. Published online 2020 May 20. doi: 10.1210/endocr/bqaa082

PMCID:: PMC7316368

Abstract Article

Select item 73022435.

Suppression of Mig-6 overcomes the acquired EGFR-TKI resistance of lung adenocarcinoma

Da Hyun Kang, Sung Soo Jung, Min-Kyung Yeo, Da Hye Lee, Geon Yoo, Sang Yeon Cho, In-Jae Oh, Ju-Ock Kim, Hee Sun Park, Chaeuk Chung, Jeong Eun Lee

BMC Cancer. 2020; 20: 571. Published online 2020 Jun 18. doi: 10.1186/s12885-020-07057-z

PMCID:: PMC7302243

Abstract Article PDF–4.3M

Select item 69772616.

An integrated analysis of public genomic data unveils a possible functional mechanism of psoriasis risk via a long-range ERRFI1 enhancer

Naoto Kubota, Mikita Suyama

BMC Med Genomics. 2020; 13: 8. Published online 2020 Jan 22. doi: 10.1186/s12920-020-0662-9

PMCID:: PMC6977261

Abstract Article PDF–1.9M

Select item 48910147.

Gene 33/Mig6 inhibits hexavalent chromium-induced DNA damage and cell transformation in human lung epithelial cells

Soyoung Park, Cen Li, Hong Zhao, Zbigniew Darzynkiewicz, Dazhong Xu

Oncotarget. 2016 Feb 23; 7(8): 8916–8930. Published online 2016 Jan 9. doi: 10.18632/oncotarget.6866

PMCID:: PMC4891014

Abstract Article PDF–1.6M

Select item 47897768.

MIG6 is MEK-regulated and affects EGF-induced migration in mutant NRAS melanoma

Ha Linh Vu, Sheera Rosenbaum, Claudia Capparelli, Timothy J. Purwin, Michael A. Davies, Adam C. Berger, Andrew E. Aplin

J Invest Dermatol. Author manuscript; available in PMC 2016 May 20.

Published in final edited form as: J Invest Dermatol. 2016 Feb; 136(2): 453–463. Published online 2015 Nov 20. doi: 10.1016/j.jid.2015.11.012

PMCID:: PMC4789776

Abstract Article PDF–1.1M

Select item 44667969.

Mitogen-Inducible Gene-6 Mediates Feedback Inhibition from Mutated BRAF towards the Epidermal Growth Factor Receptor and Thereby Limits Malignant Transformation

Malgorzata Milewska, David Romano, Ana Herrero, Maria Luisa Guerriero, Marc Birtwistle, Franz Quehenberger, Stefan Hatzl, Boris N. Kholodenko, Oreste Segatto, Walter Kolch, Armin Zebisch

PLoS One. 2015; 10(6): e0129859. Published online 2015 Jun 12. doi: 10.1371/journal.pone.0129859

PMCID:: PMC4466796

Abstract Article PDF–4.1M

Select item 380997710.

Novel ERBB Receptor Feedback Inhibitor 1 (ERRFI1) + 808 T/G Polymorphism Confers Protective Effect on Diabetic Nephropathy in a Korean Population

Ihn Suk Lee, Ju Hee Lee, Hyun Jin Kim, Jae Min Lee, Seong Kyu Lee, Hye Soo Kim, Jong Min Lee, Kang Seo Park, Bon Jeong Ku

Dis Markers. 2013; 34(2): 113–120. Published online 2013 Jan 24. doi: 10.3233/DMA-120949

PMCID:: PMC3809977

Abstract PDF–445K

Select item 337352611.

Cancer-Type Regulation of MIG-6 Expression by Inhibitors of Methylation and Histone Deacetylation

Yu-Wen Zhang, Ben Staal, Karl J. Dykema, Kyle A. Furge, George F. Vande Woude

PLoS One. 2012; 7(6): e38955. Published online 2012 Jun 12. doi: 10.1371/journal.pone.0038955

PMCID:: PMC3373526

Abstract Article PDF–5.7M

Select item 322439312.

Epidermal growth factor receptor mutation in combination with expression of MIG6 alters gefitinib sensitivity

Yoshimi Naruo, Takeshi Nagashima, Ryoko Ushikoshi-Nakayama, Yuko Saeki, Takashi Nakakuki, Takashi Naka, Hiroshi Tanaka, Shih-Feng Tsai, Mariko Okada-Hatakeyama

BMC Syst Biol. 2011; 5: 29. Published online 2011 Feb 18. doi: 10.1186/1752-0509-5-29

PMCID:: PMC3224393

Abstract Article PDF–741K

Select item 784468413.

MicroRNA-374a Promotes Hepatocellular Carcinoma Cell Proliferation by Targeting Mitogen-Inducible Gene 6 (MIG-6)

Hui Li, Huicheng Chen, Haibin Wang, Yilong Dong, Min Yin, Liang Zhang, Jia Wei

Oncol Res. 2018; 26(4): 557–563. Published online 2018 May 7. doi: 10.3727/096504017X15000784459799

Retraction in:: Oncol Res. 2024; 32(11): 1827.

PMCID:: PMC7844684

Abstract Article

Select item 642209814.

The metastasis suppressor NDRG1 down-regulates the epidermal growth factor receptor via a lysosomal mechanism by up-regulating mitogen-inducible gene 6

Sharleen V. Menezes, Zaklina Kovacevic, Des R. Richardson

J Biol Chem. 2019 Mar 15; 294(11): 4045–4064. Published online 2019 Jan 24. doi: 10.1074/jbc.RA118.006279

Correction in:: J Biol Chem. 2019 Aug 2; 294(31): 11675.

PMCID:: PMC6422098

Abstract Article PDF–6.9M

Select item 597568615.

MIG-6 suppresses endometrial epithelial cell proliferation by inhibiting phospho-AKT

Jung-Yoon Yoo, Hee-Bum Kang, Russell R. Broaddus, John I. Risinger, Kyung-Chul Choi, Tae Hoon Kim

BMC Cancer. 2018; 18: 605. Published online 2018 May 29. doi: 10.1186/s12885-018-4502-7

PMCID:: PMC5975686

Abstract Article PDF–1.9M

Select item 522650016.

Inhibition of Cdc42 is essential for Mig-6 suppression of cell migration induced by EGF

Xinni Jiang, MengMeng Niu, Deshi Chen, Jing Chen, Yang Cao, Xiaorong Li, Haoqiang Ying, Johann Bergholz, Yujun Zhang, Zhi-Xiong Xiao

Oncotarget. 2016 Aug 2; 7(31): 49180–49193. Published online 2016 Jun 21. doi: 10.18632/oncotarget.10205

PMCID:: PMC5226500

Abstract Article PDF–12M

Select item 423008017.

Mig-6 overcomes gefitinib resistance by inhibiting EGFR/ERK pathway in non-small cell lung cancer cell lines

Zi-Xuan Li, Lian-Yue Qu, Hi Wen, Hong-Shan Zhong, Ke Xu, Xue-Shan Qiu, En-Hua Wang

Int J Clin Exp Pathol. 2014; 7(10): 7304–7311. Published online 2014 Sep 15.

PMCID:: PMC4230080

Abstract Article PDF–800K

Select item 372956518.

The Relative Expression of Mig6 and EGFR Is Associated with Resistance to EGFR Kinase Inhibitors

Xiaofei Chang, Eugene Izumchenko, Luisa M. Solis, Myoung Sook Kim, Aditi Chatterjee, Shizhang Ling, Constance L. Monitto, Paul M. Harari, Manuel Hidalgo, Steve N. Goodman, Ignacio I. Wistuba, Atul Bedi, David Sidransky

PLoS One. 2013; 8(7): e68966. Published online 2013 Jul 31. doi: 10.1371/journal.pone.0068966