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Select item 79055781.

Dominant mutations in MIEF1 affect mitochondrial dynamics and cause a singular late onset optic neuropathy

Majida Charif, Yvette C. Wong, Soojin Kim, Agnès Guichet, Catherine Vignal, Xavier Zanlonghi, Philippe Bensaid, Vincent Procaccio, Dominique Bonneau, Patrizia Amati-Bonneau, Pascal Reynier, Dimitri Krainc, Guy Lenaers

Mol Neurodegener. 2021; 16: 12. Published online 2021 Feb 25. doi: 10.1186/s13024-021-00431-w

PMCID:: PMC7905578

Abstract Article PDF–2.9M

Select item 40143262.

Expression, purification, crystallization and preliminary crystallographic study of the cytoplasmic domain of the mitochondrial dynamics protein MiD51

Jun Ma, Fei Sun

Acta Crystallogr F Struct Biol Commun. 2014 May 1; 70(Pt 5): 596–599. Published online 2014 Apr 15. doi: 10.1107/S2053230X14006827

PMCID:: PMC4014326

Abstract Article PDF–310K

Select item 94371193.

Mid51/Fis1 mitochondrial oligomerization complex drives lysosomal untethering and network dynamics

Yvette C. Wong, Soojin Kim, Jasmine Cisneros, Catherine G. Molakal, Pingping Song, Steven J. Lubbe, Dimitri Krainc

J Cell Biol. 2022 Oct 3; 221(10): e202206140. Published online 2022 Aug 31. doi: 10.1083/jcb.202206140

PMCID:: PMC9437119

Abstract Article PDF–9.9M

Select item 60501304.

Epigenetic dysregulation of the Drp1 binding partners MiD49 and MiD51 increases mitotic mitochondrial fission and promotes pulmonary arterial hypertension: mechanistic and therapeutic implications

Kuang-Hueih Chen, Asish Dasgupta, Jianhui Lin, Francois Potus, Sebastien Bonnet, James Iremonger, Jennifer Fu, Jeffrey Mewburn, Danchen Wu, Kimberly Dunham-Snary, Anne L. Theilmann, Zhi-Cheng Jing, Charles Hindmarch, Mark L. Ormiston, Allan Lawrie, Stephen L. Archer

Circulation. Author manuscript; available in PMC 2019 Jul 17.

Published in final edited form as: Circulation. 2018 Jul 17; 138(3): 287–304. Published online 2018 Feb 5. doi: 10.1161/CIRCULATIONAHA.117.031258

PMCID:: PMC6050130

Abstract Article PDF–3.1M

Select item 68731745.

The phosphorylation status of Ser-637 in dynamin-related protein 1 (Drp1) does not determine Drp1 recruitment to mitochondria

Rong Yu, Tong Liu, Chenfei Ning, Fei Tan, Shao-Bo Jin, Urban Lendahl, Jian Zhao, Monica Nistér

J Biol Chem. 2019 Nov 15; 294(46): 17262–17277. Published online 2019 Sep 18. doi: 10.1074/jbc.RA119.008202

PMCID:: PMC6873174

Abstract Article PDF–8.0M

Select item 57036456.

Deep transcriptome annotation enables the discovery and functional characterization of cryptic small proteins

Sondos Samandi, Annie V Roy, Vivian Delcourt, Jean-François Lucier, Jules Gagnon, Maxime C Beaudoin, Benoît Vanderperre, Marc-André Breton, Julie Motard, Jean-François Jacques, Mylène Brunelle, Isabelle Gagnon-Arsenault, Isabelle Fournier, Aida Ouangraoua, Darel J Hunting, Alan A Cohen, Christian R Landry, Michelle S Scott, Xavier Roucou

eLife. 2017; 6: e27860. Published online 2017 Oct 30. doi: 10.7554/eLife.27860

PMCID:: PMC5703645

Abstract Article PDF–3.0M

Select item 47724997.

Drp1-dependent mitochondrial fission via MiD49/51 is essential for apoptotic cristae remodeling

Hidenori Otera, Non Miyata, Osamu Kuge, Katsuyoshi Mihara

J Cell Biol. 2016 Feb 29; 212(5): 531–544. doi: 10.1083/jcb.201508099

PMCID:: PMC4772499

Abstract Article PDF–3.9M

Select item 68445048.

Loss of MIEF1/MiD51 confers susceptibility to BAX-mediated cell death and PINK1-PRKN-dependent mitophagy

Hongxu Xian, Yih-Cherng Liou

Autophagy. 2019; 15(12): 2107–2125. Published online 2019 Mar 28. doi: 10.1080/15548627.2019.1596494

PMCID:: PMC6844504

Abstract Article PDF–9.5M

Select item 58142009.

Drp1/Fis1 interaction mediates mitochondrial dysfunction, bioenergetic failure and cognitive decline in Alzheimer's disease

Amit U. Joshi, Nay L. Saw, Mehrdad Shamloo, Daria Mochly-Rosen

Oncotarget. 2018 Jan 19; 9(5): 6128–6143. Published online 2017 Dec 22. doi: 10.18632/oncotarget.23640

PMCID:: PMC5814200

Abstract Article PDF–5.6M

Select item 312827510.

MiD49 and MiD51, new components of the mitochondrial fission machinery

Catherine S Palmer, Laura D Osellame, David Laine, Olga S Koutsopoulos, Ann E Frazier, Michael T Ryan

EMBO Rep. 2011 Jun; 12(6): 565–573. Published online 2011 Apr 21. doi: 10.1038/embor.2011.54

PMCID:: PMC3128275

Abstract Article PDF–1.7M

Select item 644341111.

MIEF1 Microprotein Regulates Mitochondrial Translation

Annie Rathore, Qian Chu, Dan Tan, Thomas F. Martinez, Cynthia J. Donaldson, Jolene K. Diedrich, John R. Yates, III, Alan Saghatelian

Biochemistry. Author manuscript; available in PMC 2019 Apr 1.

Published in final edited form as: Biochemistry. 2018 Sep 25; 57(38): 5564–5575. Published online 2018 Sep 14. doi: 10.1021/acs.biochem.8b00726

PMCID:: PMC6443411

Abstract Article PDF–1.4M

Select item 316025512.

Human MIEF1 recruits Drp1 to mitochondrial outer membranes and promotes mitochondrial fusion rather than fission

Jian Zhao, Tong Liu, Shaobo Jin, Xinming Wang, Mingqi Qu, Per Uhlén, Nikolay Tomilin, Oleg Shupliakov, Urban Lendahl, Monica Nistér

EMBO J. 2011 Jul 20; 30(14): 2762–2778. Published online 2011 Jun 24. doi: 10.1038/emboj.2011.198

PMCID:: PMC3160255

Abstract Article PDF–5.2M

Select item 392696113.

Structural and functional analysis of MiD51, a dynamin receptor required for mitochondrial fission

Viviane Richter, Catherine S. Palmer, Laura D. Osellame, Abeer P. Singh, Kirstin Elgass, David A. Stroud, Hiromi Sesaki, Marc Kvansakul, Michael T. Ryan

J Cell Biol. 2014 Feb 17; 204(4): 477–486. doi: 10.1083/jcb.201311014

PMCID:: PMC3926961

Abstract Article PDF–2.8M

Select item 362525514.

Interchangeable adaptors regulate mitochondrial dynamin assembly for membrane scission

Sajjan Koirala, Qian Guo, Raghav Kalia, Huyen T. Bui, Debra M. Eckert, Adam Frost, Janet M. Shaw

Proc Natl Acad Sci U S A. 2013 Apr 9; 110(15): E1342–E1351. Published online 2013 Mar 25. doi: 10.1073/pnas.1300855110

PMCID:: PMC3625255

Abstract Article PDF–1.5M

Select item 438322915.

Translation of 5′ leaders is pervasive in genes resistant to eIF2 repression

Dmitry E Andreev, Patrick BF O'Connor, Ciara Fahey, Elaine M Kenny, Ilya M Terenin, Sergey E Dmitriev, Paul Cormican, Derek W Morris, Ivan N Shatsky, Pavel V Baranov

eLife. 2015; 4: e03971. Published online 2015 Jan 26. doi: 10.7554/eLife.03971