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Select item 86827701.

Functional role and ribosomal position of the unique N-terminal region of DHX29, a factor required for initiation on structured mammalian mRNAs

Trevor R Sweeney, Vidya Dhote, Ewelina Guca, Christopher U T Hellen, Yaser Hashem, Tatyana V Pestova

Nucleic Acids Res. 2021 Dec 16; 49(22): 12955–12969. Published online 2021 Dec 9. doi: 10.1093/nar/gkab1192

PMCID:: PMC8682770

Abstract Article PDF–7.1M

Select item 48721092.

DHX29 reduces leaky scanning through an upstream AUG codon regardless of its nucleotide context

Vera P. Pisareva, Andrey V. Pisarev

Nucleic Acids Res. 2016 May 19; 44(9): 4252–4265. Published online 2016 Apr 11. doi: 10.1093/nar/gkw240

Expression of Concern in:: Nucleic Acids Res. 2021 Mar 18; 49(5): 3001.

PMCID:: PMC4872109

Abstract Article PDF–1.2M

Select item 29485713.

Translation initiation on mammalian mRNAs with structured 5′-UTRs requires DExH-box protein DHX29

Vera P. Pisareva, Andrey V. Pisarev, Anton A. Komar, Christopher U. T. Hellen, Tatyana V. Pestova

Cell. Author manuscript; available in PMC 2010 Oct 1.

Published in final edited form as: Cell. 2008 Dec 26; 135(7): 1237–1250. doi: 10.1016/j.cell.2008.10.037

PMCID:: PMC2948571

Abstract Article PDF–3.1M

Select item 58342114.

DHX29 functions as an RNA co-sensor for MDA5-mediated EMCV-specific antiviral immunity

Qingyuan Zhu, Peng Tan, Yinyin Li, Meng Lin, Chaoran Li, Jingrong Mao, Jun Cui, Wei Zhao, Helen Y. Wang, Rong-Fu Wang

PLoS Pathog. 2018 Feb; 14(2): e1006886. Published online 2018 Feb 20. doi: 10.1371/journal.ppat.1006886

PMCID:: PMC5834211

Abstract Article PDF–4.8M

Select item 51132065.

DHX29 and eIF3 cooperate in ribosomal scanning on structured mRNAs during translation initiation

Vera P. Pisareva, Andrey V. Pisarev

RNA. 2016 Dec; 22(12): 1859–1870. doi: 10.1261/rna.057851.116

PMCID:: PMC5113206

Abstract Article PDF–871K

Select item 40406246.

Helicase proteins DHX29 and RIG-I cosense cytosolic nucleic acids in the human airway system

Naoshi Sugimoto, Hiroki Mitoma, Taeil Kim, Shino Hanabuchi, Yong-Jun Liu

Proc Natl Acad Sci U S A. 2014 May 27; 111(21): 7747–7752. Published online 2014 May 12. doi: 10.1073/pnas.1400139111

PMCID:: PMC4040624

Abstract Article PDF–1.4M

Select item 37308277.

Structure of the mammalian ribosomal 43S preinitiation complex bound to the scanning factor DHX29

Yaser Hashem, Amedee des Georges, Vidya Dhote, Robert Langlois, Hstau Y. Liao, Robert A. Grassucci, Christopher U.T. Hellen, Tatyana V. Pestova, Joachim Frank

Cell. Author manuscript; available in PMC 2013 Nov 23.

Published in final edited form as: Cell. 2013 May 23; 153(5): 1108–1119. doi: 10.1016/j.cell.2013.04.036

PMCID:: PMC3730827

Abstract Article PDF–7.8M

Select item 35031748.

Roles of individual domains in the function of DHX29, an essential factor required for translation of structured mammalian mRNAs

Vidya Dhote, Trevor R. Sweeney, Natalia Kim, Christopher U. T. Hellen, Tatyana V. Pestova

Proc Natl Acad Sci U S A. 2012 Nov 13; 109(46): E3150–E3159. Published online 2012 Oct 9. doi: 10.1073/pnas.1208014109

PMCID:: PMC3503174

Abstract Article PDF–3.3M

Select item 27997479.

The helicase protein DHX29 promotes translation initiation, cell proliferation, and tumorigenesis

Armen Parsyan, David Shahbazian, Yvan Martineau, Emmanuel Petroulakis, Tommy Alain, Ola Larsson, Geraldine Mathonnet, Gritta Tettweiler, Christopher U. Hellen, Tatyana V. Pestova, Yuri V. Svitkin, Nahum Sonenberg

Proc Natl Acad Sci U S A. 2009 Dec 29; 106(52): 22217–22222. Published online 2009 Dec 11. doi: 10.1073/pnas.0909773106

PMCID:: PMC2799747

Abstract Article PDF–10M

Select item 957475210.

The OTUD6B‐LIN28B‐MYC axis determines the proliferative state in multiple myeloma

Carmen Paulmann, Ria Spallek, Oleksandra Karpiuk, Michael Heider, Isabell Schäffer, Jana Zecha, Susan Klaeger, Michaela Walzik, Rupert Öllinger, Thomas Engleitner, Matthias Wirth, Ulrich Keller, Jan Krönke, Martina Rudelius, Susanne Kossatz, Roland Rad, Bernhard Kuster, Florian Bassermann

EMBO J. 2022 Oct; 41(20): e110871. Published online 2022 Sep 5. doi: 10.15252/embj.2022110871

PMCID:: PMC9574752

Abstract Article PDF–4.3M

Select item 634487111.

ITCH nuclear translocation and H1.2 polyubiquitination negatively regulate the DNA damage response

Lufen Chang, Lei Shen, Hu Zhou, Jing Gao, Hangyi Pan, Li Zheng, Brian Armstrong, Yang Peng, Guang Peng, Binhua P Zhou, Steven T Rosen, Binghui Shen

Nucleic Acids Res. 2019 Jan 25; 47(2): 824–842. Published online 2018 Dec 4. doi: 10.1093/nar/gky1199

PMCID:: PMC6344871

Abstract Article PDF–6.8M

Select item 731613112.

EIF3H orchestrates Hippo pathway-mediated oncogenesis via catalytic control of YAP stability

Zhuan Zhou, Honghong Zhou, Luca Ponzoni, Aiping Luo, Rui Zhu, Mingjing He, Yi Huang, Kun-Liang Guan, Ivet Bahar, Zhihua Liu, Yong Wan

Cancer Res. Author manuscript; available in PMC 2020 Dec 15.

Published in final edited form as: Cancer Res. 2020 Jun 15; 80(12): 2550–2563. Published online 2020 Apr 8. doi: 10.1158/0008-5472.CAN-19-3718

PMCID:: PMC7316131

Abstract Article PDF–1.7M

Select item 1015862413.

The RNA‐binding protein Snd1/Tudor‐SN regulates hypoxia‐responsive gene expression

Juha Saarikettu, Saara Lehmusvaara, Marko Pesu, Ilkka Junttila, Juha Partanen, Petra Sipilä, Matti Poutanen, Jie Yang, Teemu Haikarainen, Olli Silvennoinen

FASEB Bioadv. 2023 May; 5(5): 183–198. Published online 2023 Feb 21. doi: 10.1096/fba.2022-00115

PMCID:: PMC10158624

Abstract Article PDF–7.2M

Select item 683439114.

Integrated proteogenetic analysis reveals the landscape of a mitochondrial-autophagosome synapse during PARK2-dependent mitophagy

Jin-Mi Heo, Nathan J. Harper, Joao A. Paulo, Mamie Li, Qikai Xu, Margaret Coughlin, Stephen J. Elledge, J. Wade Harper

Sci Adv. 2019 Nov; 5(11): eaay4624. Published online 2019 Nov 6. doi: 10.1126/sciadv.aay4624

PMCID:: PMC6834391

Abstract Article PDF–2.6M

Select item 951327115.

Proximity labeling of endogenous RICTOR identifies mTOR complex 2 regulation by ADP ribosylation factor ARF1

Amelia K. Luciano, Ekaterina D. Korobkina, Scott P. Lyons, John A. Haley, Shelagh M. Fluharty, Su Myung Jung, Arminja N. Kettenbach, David A. Guertin

J Biol Chem. 2022 Oct; 298(10): 102379. Published online 2022 Aug 13. doi: 10.1016/j.jbc.2022.102379

PMCID:: PMC9513271

Abstract Article PDF–2.7M

Select item 682384616.

BioID Performed on Golgi Enriched Fractions Identify C10orf76 as a GBF1 Binding Protein Essential for Golgi Maintenance and Secretion

Calvin J. Chan, Roberta Le, Kaylan Burns, Khadra Ahmed, Etienne Coyaud, Estelle M. N. Laurent, Brian Raught, Paul Melançon

Mol Cell Proteomics. 2019 Nov; 18(11): 2285–2297. Published online 2019 Sep 13. doi: 10.1074/mcp.RA119.001645

PMCID:: PMC6823846

Abstract Article PDF–2.2M

Select item 801772017.

SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors

Ukhyun Jo, Yasuhisa Murai, Sirisha Chakka, Lu Chen, Ken Cheng, Junko Murai, Liton Kumar Saha, Lisa M. Miller Jenkins, Yves Pommier

Proc Natl Acad Sci U S A. 2021 Feb 9; 118(6): e2015654118. Published online 2021 Feb 3. doi: 10.1073/pnas.2015654118

PMCID:: PMC8017720

Abstract Article PDF–1.9M

Select item 787370118.

Global proteomics of Ubqln2-based murine models of ALS

Alexandra M. Whiteley, Miguel A. Prado, Stefanie A.H. de Poot, Joao A. Paulo, Marissa Ashton, Sara Dominguez, Martin Weber, Hai Ngu, John Szpyt, Mark P. Jedrychowski, Amy Easton, Steven P. Gygi, Thimo Kurz, Mervyn J. Monteiro, Eric J. Brown, Daniel Finley

J Biol Chem. 2021 Jan-Jun; 296: 100153. Published online 2020 Dec 10. doi: 10.1074/jbc.RA120.015960

PMCID:: PMC7873701

Abstract Article PDF–3.0M

Select item 821018419.

Elucidation of the BMI1 interactome identifies novel regulatory roles in glioblastoma

Verónica Freire-Benéitez, Nicola Pomella, Thomas O Millner, Anaëlle A Dumas, Maria Victoria Niklison-Chirou, Eleni Maniati, Jun Wang, Vinothini Rajeeve, Pedro Cutillas, Silvia Marino

NAR Cancer. 2021 Mar; 3(1): zcab009. Published online 2021 Mar 22. doi: 10.1093/narcan/zcab009