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Select item 110728531.

PPARdelta activation induces metabolic and contractile maturation of human pluripotent stem-cell-derived cardiomyocytes

Nadeera M. Wickramasinghe, David Sachs, Bhavana Shewale, David M. Gonzalez, Priyanka Dhanan-Krishnan, Denis Torre, Elizabeth LaMarca, Serena Raimo, Rafael Dariolli, Madhavika N. Serasinghe, Joshua Mayourian, Robert Sebra, Kristin Beaumont, Srinivas Iyengar, Deborah L. French, Arne Hansen, Thomas Eschenhagen, Jerry E. Chipuk, Eric A. Sobie, Adam Jacobs, Schahram Akbarian, Harry Ischiropoulos, Avi Ma’ayan, Sander M. Houten, Kevin Costa, Nicole C. Dubois

Cell Stem Cell. Author manuscript; available in PMC 2024 May 6.

Published in final edited form as: Cell Stem Cell. 2022 Apr 7; 29(4): 559–576.e7. Published online 2022 Mar 23. doi: 10.1016/j.stem.2022.02.011

PMCID:: PMC11072853

Abstract Article PDF–3.7M

Select item 88052122.

Crystal structures of the ligand-binding domain of human peroxisome proliferator-activated receptor δ in complexes with phenylpropanoic acid derivatives and a pyridine carboxylic acid derivative

Takuji Oyama, Kazuki Takiguchi, Hiroyuki Miyachi

Acta Crystallogr F Struct Biol Commun. 2022 Feb 1; 78(Pt 2): 81–87. Published online 2022 Jan 31. doi: 10.1107/S2053230X22000449

PMCID:: PMC8805212

Abstract Article PDF–1.2M

Select item 83952403.

The PPARβ/δ-AMPK Connection in the Treatment of Insulin Resistance

David Aguilar-Recarte, Xavier Palomer, Walter Wahli, Manuel Vázquez-Carrera

Int J Mol Sci. 2021 Aug; 22(16): 8555. Published online 2021 Aug 9. doi: 10.3390/ijms22168555

PMCID:: PMC8395240

Abstract Article PDF–1.4M

Select item 83032904.

PPARdelta in Affected Atopic Dermatitis and Psoriasis: A Possible Role in Metabolic Reprograming

Stefan Blunder, Petra Pavel, Deborah Minzaghi, Sandrine Dubrac

Int J Mol Sci. 2021 Jul; 22(14): 7354. Published online 2021 Jul 8. doi: 10.3390/ijms22147354

PMCID:: PMC8303290

Abstract Article PDF–921K

Select item 79299605.

Recent Insights on the Role of PPAR-β/δ in Neuroinflammation and Neurodegeneration, and Its Potential Target for Therapy

Anna K. Strosznajder, Sylwia Wójtowicz, Mieszko J. Jeżyna, Grace Y. Sun, Joanna B. Strosznajder

Neuromolecular Med. 2021; 23(1): 86–98. Published online 2020 Nov 18. doi: 10.1007/s12017-020-08629-9

PMCID:: PMC7929960

Abstract Article PDF–1.1M

Select item 79187466.

Wnt/β-catenin Pathway-Mediated PPARδ Expression during Embryonic Development Differentiation and Disease

Tabinda Sidrat, Zia-Ur Rehman, Myeong-Don Joo, Kyeong-Lim Lee, Il-Keun Kong

Int J Mol Sci. 2021 Feb; 22(4): 1854. Published online 2021 Feb 12. doi: 10.3390/ijms22041854

PMCID:: PMC7918746

Abstract Article PDF–3.7M

Select item 77748827.

MicroRNA-9-5p inhibits proliferation and induces apoptosis of human hypertrophic scar fibroblasts through targeting peroxisome proliferator-activated receptor β

Chi-Yung Chai, I.-Chun Tai, Rui Zhou, Junlong Song, Chaoying Zhang, Shengrong Sun

Biol Open. 2020 Dec 15; 9(12): bio051904. Published online 2020 Dec 21. doi: 10.1242/bio.051904

PMCID:: PMC7774882

Abstract Article PDF–1.5M

Select item 72818408.

Single Nucleotide Polymorphisms in PPARD Associated with Systemic Lupus Erythematosus in Chinese Populations

Yuan-yuan Qi, Ya-ling Zhai, Xin-ran Liu, Xiao-xue Zhang, Ya-fei Zhao, Xiang-hui Ning, Zhan-Zheng Zhao

J Immunol Res. 2020; 2020: 7285747. Published online 2020 May 31. doi: 10.1155/2020/7285747

PMCID:: PMC7281840

Abstract Article PDF–406K

Select item 69098149.

PPAR δ inhibition protects against palmitic acid-LPS induced lipidosis and injury in cultured hepatocyte L02 cell

Yi Li, Chenwei Wang, Jiyuan Lu, Ke Huang, Yu Han, Junlin Chen, Yan Yang, Bin Liu

Int J Med Sci. 2019; 16(12): 1593–1603. Published online 2019 Oct 21. doi: 10.7150/ijms.37677

Correction in:: Int J Med Sci. 2023; 20(13): 1791–1792.

PMCID:: PMC6909814

Abstract Article PDF–2.5M

Select item 653376210.

Polymorphism of the PPARD Gene and Dynamic Balance Performance in Han Chinese Children

Yixuan Cao, Qiyue Zhang, Jianhua Chen, Zhiqiang Li, Zhaowei Zhou, Jiawei Shen, Dong Wang, Dun Pan, Zhuo Wang, Dandan Ke, Xiaofei Wang, Dajiang Lu, Ying Zhao, Shulin Cheng, Yongyong Shi

Hereditas. 2019; 156: 15. Published online 2019 May 23. doi: 10.1186/s41065-019-0092-x

PMCID:: PMC6533762

Abstract Article PDF–779K

Select item 635587511.

Discovering highly selective and diverse PPAR-delta agonists by ligand based machine learning and structural modeling

Benny Da’adoosh, David Marcus, Anwar Rayan, Fred King, Jianwei Che, Amiram Goldblum

Sci Rep. 2019; 9: 1106. Published online 2019 Jan 31. doi: 10.1038/s41598-019-38508-8

PMCID:: PMC6355875

Abstract Article PDF–1.7M

Select item 632889212.

The association between peroxisome proliferator-activated receptor Δ rs3777744, rs3798343, and rs6922548 and coronary artery disease

Jing Zhang, Xiu-ling Liu, Qiao-wei Jia, Chen-hui Zhao, Jie-yin Liu, Feng-hui An, Li-hua Li, Zhao-hong Chen, Lian-sheng Wang, Wen-zhu Ma, Zhi-jian Yang, En-zhi Jia

Biosci Rep. 2019 Jan 31; 39(1): BSR20181510. Prepublished online 2018 Nov 14. Published online 2019 Jan 3. doi: 10.1042/BSR20181510

PMCID:: PMC6328892

Abstract Article PDF–788K

Select item 627506313.

The Role of PPAR-δ in Metabolism, Inflammation, and Cancer: Many Characters of a Critical Transcription Factor

Yi Liu, Jennifer K. Colby, Xiangsheng Zuo, Jonathan Jaoude, Daoyan Wei, Imad Shureiqi

Int J Mol Sci. 2018 Nov; 19(11): 3339. Published online 2018 Oct 26. doi: 10.3390/ijms19113339

PMCID:: PMC6275063

Abstract Article PDF–700K

Select item 611484514.

The polymorphisms of the PPARD gene modify post-training body mass and biochemical parameter changes in women

Agata Leońska-Duniec, Pawel Cieszczyk, Zbigniew Jastrzębski, Aleksandra Jażdżewska, Ewelina Lulińska-Kuklik, Waldemar Moska, Krzysztof Ficek, Marta Niewczas, Agnieszka Maciejewska-Skrendo

PLoS One. 2018; 13(8): e0202557. Published online 2018 Aug 29. doi: 10.1371/journal.pone.0202557

PMCID:: PMC6114845

Abstract Article PDF–989K

Select item 600673715.

Associations between hypertension and the peroxisome proliferator-activated receptor-δ (PPARD) gene rs7770619 C>T polymorphism in a Korean population

Minjoo Kim, Minkyung Kim, Hye Jin Yoo, Jayoung Shon, Jong Ho Lee

Hum Genomics. 2018; 12: 28. Published online 2018 Jun 18. doi: 10.1186/s40246-018-0162-6

PMCID:: PMC6006737

Abstract Article PDF–734K

Select item 587756416.

Influence of Single-Nucleotide Polymorphisms in PPAR-δ, PPAR-γ, and PRKAA2 on the Changes in Anthropometric Indices and Blood Measurements through Exercise-Centered Lifestyle Intervention in Japanese Middle-Aged Men

Yuichiro Nishida, Minako Iyadomi, Hirotaka Tominaga, Hiroaki Taniguchi, Yasuki Higaki, Hiroaki Tanaka, Mikako Horita, Chisato Shimanoe, Megumi Hara, Keitaro Tanaka

Int J Mol Sci. 2018 Mar; 19(3): 703. Published online 2018 Mar 1. doi: 10.3390/ijms19030703

PMCID:: PMC5877564

Abstract Article PDF–234K

Select item 522036117.

Oleanolic acid ameliorates high glucose-induced endothelial dysfunction via PPARδ activation

Zihui Zhang, Manli Jiang, Xinya Xie, Haixia Yang, Xinfeng Wang, Lei Xiao, Nanping Wang

Sci Rep. 2017; 7: 40237. Published online 2017 Jan 9. doi: 10.1038/srep40237

PMCID:: PMC5220361

Abstract Article PDF–1.0M

Select item 475386318.

Circulating “LncPPARδ” From Monocytes as a Novel Biomarker for Coronary Artery Diseases

Yue Cai, Yujia Yang, Xiongwen Chen, Duofeng He, Xiaoqun Zhang, Xiulan Wen, Jiayong Hu, Chunjiang Fu, Dongfeng Qiu, Pedro A. Jose, Chunyu Zeng, Lin Zhou

Medicine (Baltimore) 2016 Feb; 95(6): e2360. Published online 2016 Feb 12. doi: 10.1097/MD.0000000000002360

PMCID:: PMC4753863

Abstract Article PDF–707K

Select item 452333119.

Activation of PPAR-δ induces microRNA-100 and decreases the uptake of very low-density lipoprotein in endothelial cells

Xi Fang, Li Fang, Ao Liu, Xiaohong Wang, Beilei Zhao, Nanping Wang

Br J Pharmacol. 2015 Aug; 172(15): 3728–3736. Published online 2015 Jun 26. doi: 10.1111/bph.13160

PMCID:: PMC4523331

Abstract Article PDF–1.2M

Select item 435614720.

PPARD +294C overrepresentation in general and long-lived population in China Bama longevity area and unique relationships between PPARD +294T/C polymorphism and serum lipid profiles

Chen-Yuan Luo, Cheng-Wu Liu, Lin Ge, Guo-Fang Pang, Ming Yang, Cai-You Hu, Ze-Ping Lv, Ning-Yuan Chen, Hai-Yan Li, Hua-Yu Wu, Yi-Yuan Wang, Rui-Xing Yin, Shang-Ling Pan, Jun-Hua Peng

Lipids Health Dis. 2015; 14: 17. Published online 2015 Mar 7. doi: 10.1186/s12944-015-0016-3

PMCID:: PMC4356147

Abstract Article PDF–1.6M

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PMC Links for Gene (Select 5467) (161)
PMC
peroxisome proliferator-activated receptor delta isoform X1 [Homo sapiens]
peroxisome proliferator-activated receptor delta isoform X1 [Homo sapiens]
gi|2462609063|ref|XP_054211692.1|

Protein
peroxisome proliferator-activated receptor delta isoform 3 [Homo sapiens]
peroxisome proliferator-activated receptor delta isoform 3 [Homo sapiens]
gi|284807157|ref|NP_001165290.1|

Protein

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