PMC Links for Gene (Select 54741) - PMC

Select item 111419411.

Whole-body deletion of Endospanin 1 protects from obesity-associated deleterious metabolic alterations

Arturo Roca-Rivada, Marcio Do Cruzeiro, Raphaël G.P. Denis, Qiang Zhang, Christine Rouault, Yves Rouillé, Jean-Marie Launay, Céline Cruciani-Guglielmacci, Virginie Mattot, Karine Clément, Ralf Jockers, Julie Dam

JCI Insight. 2024 May 8; 9(9): e168418. Published online 2024 May 8. doi: 10.1172/jci.insight.168418

PMCID:: PMC11141941

Abstract Article PDF–6.2M

Select item 29969542.

Copy number variation at leptin receptor gene locus associated with metabolic traits and the risk of type 2 diabetes mellitus

Jae-Pil Jeon, Sung-Mi Shim, Hye-Young Nam, Gil-Mi Ryu, Eun-Jung Hong, Hyung-Lae Kim, Bok-Ghee Han

BMC Genomics. 2010; 11: 426. Published online 2010 Jul 12. doi: 10.1186/1471-2164-11-426

PMCID:: PMC2996954

Abstract Article PDF–830K

Select item 30938713.

Endospanins Regulate a Postinternalization Step of the Leptin Receptor Endocytic Pathway

Karin Séron, Cyril Couturier, Sandrine Belouzard, Johan Bacart, Didier Monté, Laetitia Corset, Olivier Bocquet, Julie Dam, Virginie Vauthier, Cécile Lecœur, Bernard Bailleul, Bernard Hoflack, Philippe Froguel, Ralf Jockers, Yves Rouillé

J Biol Chem. 2011 May 20; 286(20): 17968–17981. Published online 2011 Mar 22. doi: 10.1074/jbc.M111.224857

PMCID:: PMC3093871

Abstract Article PDF–4.8M

Select item 21483144.

Silencing of OB-RGRP in mouse hypothalamic arcuate nucleus increases leptin receptor signaling and prevents diet-induced obesity

Cyril Couturier, Chamsy Sarkis, Karin Séron, Sandrine Belouzard, Patty Chen, Aude Lenain, Laetitia Corset, Julie Dam, Virginie Vauthier, Anne Dubart, Jacques Mallet, Philippe Froguel, Yves Rouillé, Ralf Jockers

Proc Natl Acad Sci U S A. 2007 Dec 4; 104(49): 19476–19481. Published online 2007 Nov 27. doi: 10.1073/pnas.0706671104

PMCID:: PMC2148314

Abstract Article PDF–430K

Select item 27867845.

LEPROT and LEPROTL1 cooperatively decrease hepatic growth hormone action in mice

Thierry Touvier, Françoise Conte-Auriol, Olivier Briand, Céline Cudejko, Réjane Paumelle, Sandrine Caron, Eric Baugé, Yves Rouillé, Jean-Pierre Salles, Bart Staels, Bernard Bailleul

J Clin Invest. 2009 Dec 1; 119(12): 3830–3838. Published online 2009 Nov 9. doi: 10.1172/JCI34997

PMCID:: PMC2786784

Abstract Article PDF–1.0M

Select item 1467996.

The leptin receptor promoter controls expression of a second distinct protein.

B Bailleul, I Akerblom, A D Strosberg

Nucleic Acids Res. 1997 Jul 15; 25(14): 2752–2758. doi: 10.1093/nar/25.14.2752

PMCID:: PMC146799

Summary PDF–373K

Select item 28752017.

Identification of Type 2 Diabetes-associated combination of SNPs using Support Vector Machine

Hyo-Jeong Ban, Jee Yeon Heo, Kyung-Soo Oh, Keun-Joon Park

BMC Genet. 2010; 11: 26. Published online 2010 Apr 23. doi: 10.1186/1471-2156-11-26

PMCID:: PMC2875201

Abstract Article PDF–1.0M

Select item 58410868.

High-content genome-wide RNAi screens identify regulators of parkin upstream of mitophagy

Samuel A. Hasson, Lesley A. Kane, Koji Yamano, Chiu-Hui Huang, Danielle A. Sliter, Eugen Buehler, Chunxin Wang, Sabrina M. Heman-Ackah, Tara Hessa, Rajarshi Guha, Scott E. Martin, Richard J. Youle

Nature. Author manuscript; available in PMC 2018 Mar 7.

Published in final edited form as: Nature. 2013 Dec 12; 504(7479): 291–295. Published online 2013 Nov 24. doi: 10.1038/nature12748

PMCID:: PMC5841086

Abstract Article PDF–5.3M

Select item 60777229.

Estrogen-regulated feedback loop limits the efficacy of estrogen receptor–targeted breast cancer therapy

Tengfei Xiao, Wei Li, Xiaoqing Wang, Han Xu, Jixin Yang, Qiu Wu, Ying Huang, Joseph Geradts, Peng Jiang, Teng Fei, David Chi, Chongzhi Zang, Qi Liao, Jonathan Rennhack, Eran Andrechek, Nanlin Li, Simone Detre, Mitchell Dowsett, Rinath M. Jeselsohn, X. Shirley Liu, Myles Brown

Proc Natl Acad Sci U S A. 2018 Jul 31; 115(31): 7869–7878. Published online 2018 Jul 9. doi: 10.1073/pnas.1722617115

PMCID:: PMC6077722

Abstract Article PDF–2.4M

Select item 537173010.

Systematic protein–protein interaction mapping for clinically relevant human GPCRs

Kate Sokolina, Saranya Kittanakom, Jamie Snider, Max Kotlyar, Pascal Maurice, Jorge Gandía, Abla Benleulmi‐Chaachoua, Kenjiro Tadagaki, Atsuro Oishi, Victoria Wong, Ramy H Malty, Viktor Deineko, Hiroyuki Aoki, Shahreen Amin, Zhong Yao, Xavier Morató, David Otasek, Hiroyuki Kobayashi, Javier Menendez, Daniel Auerbach, Stephane Angers, Natasa Pržulj, Michel Bouvier, Mohan Babu, Francisco Ciruela, Ralf Jockers, Igor Jurisica, Igor Stagljar

Mol Syst Biol. 2017 Mar; 13(3): 918. Published online 2017 Mar 15. doi: 10.15252/msb.20167430

PMCID:: PMC5371730

Abstract Article PDF–4.1M

Select item 268304711.

Ubiquitin-mediated proteolysis of HuR by heat shock

Kotb Abdelmohsen, Subramanya Srikantan, Xiaoling Yang, Ashish Lal, Hyeon Ho Kim, Yuki Kuwano, Stefanie Galban, Kevin G Becker, Davida Kamara, Rafael de Cabo, Myriam Gorospe

EMBO J. 2009 May 6; 28(9): 1271–1282. Published online 2009 Mar 26. doi: 10.1038/emboj.2009.67

PMCID:: PMC2683047

Abstract Article PDF–1.4M

Select item 294516812.

Variation at the NFATC2 Locus Increases the Risk of Thiazolidinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study

Swneke D. Bailey, Changchun Xie, Ron Do, Alexandre Montpetit, Rafael Diaz, Viswanathan Mohan, Bernard Keavney, Salim Yusuf, Hertzel C. Gerstein, James C. Engert, Sonia Anand, on behalf of the DREAM investigators

Diabetes Care. 2010 Oct; 33(10): 2250–2253. Published online 2010 Jul 13. doi: 10.2337/dc10-0452

PMCID:: PMC2945168

Abstract Article PDF–153K

Select item 277583213.

Gene-centric Association Signals for Lipids and Apolipoproteins Identified via the HumanCVD BeadChip

Philippa J. Talmud, Fotios Drenos, Sonia Shah, Tina Shah, Jutta Palmen, Claudio Verzilli, Tom R. Gaunt, Jacky Pallas, Ruth Lovering, Kawah Li, Juan Pablo Casas, Reecha Sofat, Meena Kumari, Santiago Rodriguez, Toby Johnson, Stephen J. Newhouse, Anna Dominiczak, Nilesh J. Samani, Mark Caulfield, Peter Sever, Alice Stanton, Denis C. Shields, on behalf of the ASCOT investigators, Sandosh Padmanabhan, Olle Melander, Claire Hastie, Christian Delles, on behalf of the NORDIL investigators, Shah Ebrahim, Michael G. Marmot, George Davey Smith, Debbie A. Lawlor, Patricia B. Munroe, for the BRIGHT Consortium, Ian N. Day, Mika Kivimaki, John Whittaker, Steve E. Humphries, Aroon D. Hingorani

Am J Hum Genet. 2009 Nov 13; 85(5): 628–642. doi: 10.1016/j.ajhg.2009.10.014

PMCID:: PMC2775832

Abstract Article PDF–2.8M

Select item 716998314.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x