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Items: 1 to 20 of 56

1.
Quantitative Ubiquitylome Analysis Reveals the Specificity of RNF111/Arkadia E3 Ubiquitin Ligase for its Degradative Substrates SKI and SKIL/SnoN in TGF-β Signaling Pathway
Victor Laigle, Florent Dingli, Sadek Amhaz, Tiphaine Perron, Mouna Chouchène, Sabrina Colasse, Isabelle Petit, Patrick Poullet, Damarys Loew, Céline Prunier, Laurence Levy
Mol Cell Proteomics. 2021; 20: 100173. Published online 2021 Nov 3. doi: 10.1016/j.mcpro.2021.100173
PMCID:
PMC8665411
AbstractArticlePDF–3.3M
2.
Arkadia/RNF111 is a SUMO-targeted ubiquitin ligase with preference for substrates marked with SUMO1-capped SUMO2/3 chain
Annie M. Sriramachandran, Katrin Meyer-Teschendorf, Stefan Pabst, Helle D. Ulrich, Niels H. Gehring, Kay Hofmann, Gerrit J. K. Praefcke, R. Jürgen Dohmen
Nat Commun. 2019; 10: 3678. Published online 2019 Aug 15. doi: 10.1038/s41467-019-11549-3
PMCID:
PMC6695498
AbstractArticlePDF–1.8M
3.
Arkadia (RING Finger Protein 111) Mediates Sumoylation-Dependent Stabilization of Nrf2 Through K48-Linked Ubiquitination
Deneshia J. McIntosh, Treniqka S. Walters, Ifeanyi J. Arinze, Jamaine S. Davis
Cell Physiol Biochem. Author manuscript; available in PMC 2019 Jun 27.
Published in final edited form as: Cell Physiol Biochem. 2018; 46(1): 418–430. Published online 2018 Mar 23. doi: 10.1159/000488475
PMCID:
PMC6595223
AbstractArticlePDF–889K
4.
Arkadia protein expression is reduced in the liver during the progression of hepatic fibrosis
Fei Hou, Ruixia Liu, Xiaoya Liu, Lijian Cui, Xiaozheng Yu, Yan Wen, Huiguo Ding, Chenghong Yin
Int J Mol Med. 2018 Mar; 41(3): 1315–1322. Published online 2017 Dec 22. doi: 10.3892/ijmm.2017.3340
PMCID:
PMC5819942
AbstractArticlePDF–1.0M
5.
SUMO and ubiquitin-dependent XPC exchange drives nucleotide excision repair
Loes van Cuijk, Gijsbert J. van Belle, Yasemin Turkyilmaz, Sara L. Poulsen, Roel C. Janssens, Arjan F. Theil, Mariangela Sabatella, Hannes Lans, Niels Mailand, Adriaan B. Houtsmuller, Wim Vermeulen, Jurgen A. Marteijn
Nat Commun. 2015; 6: 7499. Published online 2015 Jul 7. doi: 10.1038/ncomms8499
PMCID:
PMC4501428
AbstractArticlePDF–1.3M
6.
Arkadia regulates tumor metastasis by modulation of the TGF-β pathway
Marco A. Briones-Orta, Laurence Levy, Chris D. Madsen, Debipriya Das, Yigit Erker, Erik Sahai, Caroline S. Hill
Cancer Res. Author manuscript; available in PMC 2013 Sep 15.
Published in final edited form as: Cancer Res. 2013 Mar 15; 73(6): 1800–1810. Published online 2013 Mar 6. doi: 10.1158/0008-5472.CAN-12-1916
PMCID:
PMC3672972
AbstractArticlePDF–3.0M
7.
RNF111-dependent neddylation activates DNA damage-induced ubiquitination
Teng Ma, Yibin Chen, Feng Zhang, Chao-Yie Yang, Shaomeng Wang, Xiaochun Yu
Mol Cell. Author manuscript; available in PMC 2014 Mar 7.
Published in final edited form as: Mol Cell. 2013 Mar 7; 49(5): 897–907. Published online 2013 Feb 7. doi: 10.1016/j.molcel.2013.01.006
PMCID:
PMC3595365
AbstractArticlePDF–3.7M
8.
The Four and a Half LIM-only Protein 2 (FHL2) Activates Transforming Growth Factor β (TGF-β) Signaling by Regulating Ubiquitination of the E3 Ligase Arkadia
Tian Xia, Laurence Lévy, Florence Levillayer, Baosen Jia, Gaiyun Li, Christine Neuveut, Marie-Annick Buendia, Ke Lan, Yu Wei
J Biol Chem. 2013 Jan 18; 288(3): 1785–1794. Published online 2012 Dec 4. doi: 10.1074/jbc.M112.439760
PMCID:
PMC3548488
AbstractArticlePDF–1.8M
9.
Enhancement of TGF-β Signaling Responses by the E3 Ubiquitin Ligase Arkadia Provides Tumor Suppression in Colorectal Cancer
Vikas Sharma, Anna G. Antonacopoulou, Shinya Tanaka, Alexios A. Panoutsopoulos, Vasiliki Bravou, Haralabos P. Kalofonos, Vasso Episkopou
Cancer Res. Author manuscript; available in PMC 2012 Apr 15.
Published in final edited form as: Cancer Res. 2011 Oct 15; 71(20): 6438–6449. doi: 10.1158/0008-5472.CAN-11-1645
PMCID:
PMC3194767
AbstractArticlePDF–2.4M
10.
The Arkadia-ESRP2 axis suppresses tumor progression: analyses in clear-cell renal cell carcinoma
A Mizutani, D Koinuma, H Seimiya, K Miyazono
Oncogene. 2016 Jul 7; 35(27): 3514–3523. Published online 2015 Nov 2. doi: 10.1038/onc.2015.412
PMCID:
PMC5399154
AbstractArticlePDF–1.1M
11.
Unveiling the Essential Role of Arkadia’s Non-RING Elements in the Ubiquitination Process
Maria Birkou, Georgia N. Delegkou, Konstantinos D. Marousis, Nefeli Fragkaki, Tamara Toro, Vasso Episkopou, Georgios A. Spyroulias
Int J Mol Sci. 2022 Sep; 23(18): 10585. Published online 2022 Sep 13. doi: 10.3390/ijms231810585
PMCID:
PMC9501438
AbstractArticlePDF–8.7M
12.
E2 Partner Tunes the Ubiquitylation Specificity of Arkadia E3 Ubiquitin Ligase
Georgia N. Delegkou, Maria Birkou, Nefeli Fragkaki, Tamara Toro, Konstantinos D. Marousis, Vasso Episkopou, Georgios A. Spyroulias
Cancers (Basel) 2023 Feb; 15(4): 1040. Published online 2023 Feb 7. doi: 10.3390/cancers15041040
PMCID:
PMC9954413
AbstractArticlePDF–20M
13.
Multiple Arkadia/RNF111 Structures Coordinate Its Polycomb Body Association and Transcriptional Control
Huaiyu Sun, Yijing Liu, Tony Hunter
Mol Cell Biol. 2014 Aug; 34(16): 2981–2995. doi: 10.1128/MCB.00036-14
PMCID:
PMC4135591
AbstractArticlePDF–2.2M
14.
Arkadia Activates Smad3/Smad4-Dependent Transcription by Triggering Signal-Induced SnoN Degradation
Laurence Levy, Michael Howell, Debipriya Das, Sean Harkin, Vasso Episkopou, Caroline S. Hill
Mol Cell Biol. 2007 Sep; 27(17): 6068–6083. Published online 2007 Jun 25. doi: 10.1128/MCB.00664-07
PMCID:
PMC1952153
AbstractArticlePDF–2.1M
15.
A Regulatory Path Associated with X-Linked Intellectual Disability and Epilepsy Links KDM5C to the Polyalanine Expansions in ARX
Loredana Poeta, Francesca Fusco, Denise Drongitis, Cheryl Shoubridge, Genesia Manganelli, Stefania Filosa, Mariateresa Paciolla, Monica Courtney, Patrick Collombat, Maria Brigida Lioi, Jozef Gecz, Matilde Valeria Ursini, Maria Giuseppina Miano
Am J Hum Genet. 2013 Jan 10; 92(1): 114–125. doi: 10.1016/j.ajhg.2012.11.008
PMCID:
PMC3542471
AbstractArticlePDF–1.0M
16.
Variants in Several Genomic Regions Associated with Asperger Disorder
D. Salyakina, D.Q. Ma, J.M. Jaworski, I. Konidari, P.L. Whitehead, R. Henson, D. Martinez, J.L. Robinson, S. Sacharow, H.H. Wright, R.K. Abramson, J.R. Gilbert, M.L. Cuccaro, M.A. Pericak-Vance
Autism Res. Author manuscript; available in PMC 2015 May 18.
Published in final edited form as: Autism Res. 2010 Dec; 3(6): 303–310. doi: 10.1002/aur.158
PMCID:
PMC4435556
AbstractArticlePDF–357K
17.
RB1CC1 Protein Positively Regulates Transforming Growth Factor-β Signaling through the Modulation of Arkadia E3 Ubiquitin Ligase Activity
Daizo Koinuma, Masahiko Shinozaki, Yoshiko Nagano, Hiroaki Ikushima, Kana Horiguchi, Kouichiro Goto, Tokuhiro Chano, Masao Saitoh, Takeshi Imamura, Kohei Miyazono, Keiji Miyazawa
J Biol Chem. 2011 Sep 16; 286(37): 32502–32512. Published online 2011 Jul 27. doi: 10.1074/jbc.M111.227561
PMCID:
PMC3173165
AbstractArticlePDF–4.7M
18.
OVOL1 inhibits breast cancer cell invasion by enhancing the degradation of TGF-β type I receptor
Chuannan Fan, Qian Wang, Gerard van der Zon, Jiang Ren, Cedrick Agaser, Roderick C. Slieker, Prasanna Vasudevan Iyengar, Hailiang Mei, Peter ten Dijke
Signal Transduct Target Ther. 2022; 7: 126. Published online 2022 Apr 29. doi: 10.1038/s41392-022-00944-w
PMCID:
PMC9050647
AbstractArticlePDF–6.9M
19.
Common variation contributes to the genetic architecture of social communication traits
Beate St Pourcain, Andrew J O Whitehouse, Wei Q Ang, Nicole M Warrington, Joseph T Glessner, Kai Wang, Nicholas J Timpson, David M Evans, John P Kemp, Susan M Ring, Wendy L McArdle, Jean Golding, Hakon Hakonarson, Craig E Pennell, George Davey Smith
Mol Autism. 2013; 4: 34. Published online 2013 Sep 18. doi: 10.1186/2040-2392-4-34
PMCID:
PMC3853437
AbstractArticlePDF–2.0M
20.
Arkadia amplifies TGF-β superfamily signalling through degradation of Smad7
Daizo Koinuma, Masahiko Shinozaki, Akiyoshi Komuro, Kouichiro Goto, Masao Saitoh, Aki Hanyu, Masahito Ebina, Toshihiro Nukiwa, Keiji Miyazawa, Takeshi Imamura, Kohei Miyazono
EMBO J. 2003 Dec 15; 22(24): 6458–6470. doi: 10.1093/emboj/cdg632
PMCID:
PMC291827
AbstractArticlePDF–669K

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