U.S. flag

An official website of the United States government

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Links from Gene

Items: 1 to 20 of 51

1.
Human promoter directionality is determined by transcriptional initiation and the opposing activities of INTS11 and CDK9
Joshua D Eaton, Jessica Board, Lee Davidson, Chris Estell, Steven West
eLife. 2024; 13: RP92764. Published online 2024 Jul 8. doi: 10.7554/eLife.92764
PMCID:
PMC11230626
AbstractArticlePDF–2.3M
2.
An examination of the metal ion content in the active sites of human endonucleases CPSF73 and INTS11
Ji Huang, Xiangyang Liu, Yadong Sun, Zhuang Li, Min-Han Lin, Keith Hamilton, Corey R. Mandel, Felix Sandmeir, Elena Conti, Paul H. Oyala, Liang Tong
J Biol Chem. 2023 Apr; 299(4): 103047. Published online 2023 Feb 22. doi: 10.1016/j.jbc.2023.103047
PMCID:
PMC10064220
AbstractArticlePDF–1.4M
3.
NACK and INTEGRATOR act coordinately to activate Notch-mediated transcription in tumorigenesis
Elena Shersher, Mohini Lahiry, Annamil Alvarez-Trotta, Giulia Diluvio, David J. Robbins, Ramin Shiekhattar, Anthony J. Capobianco
Cell Commun Signal. 2021; 19: 96. Published online 2021 Sep 22. doi: 10.1186/s12964-021-00776-1
PMCID:
PMC8456597
AbstractArticlePDF–2.0M
4.
Molecular basis for the interaction between Integrator subunits IntS9 and IntS11 and its functional importance
Yixuan Wu, Todd R. Albrecht, David Baillat, Eric J. Wagner, Liang Tong
Proc Natl Acad Sci U S A. 2017 Apr 25; 114(17): 4394–4399. Published online 2017 Apr 10. doi: 10.1073/pnas.1616605114
PMCID:
PMC5410846
AbstractArticlePDF–1.1M
5.
snRNA 3′ End Formation Requires Heterodimeric Association of Integrator Subunits
Todd R. Albrecht, Eric J. Wagner
Mol Cell Biol. 2012 Mar; 32(6): 1112–1123. doi: 10.1128/MCB.06511-11
PMCID:
PMC3295014
AbstractArticlePDF–1.6M
6.
A CPSF-73 Homologue Is Required for Cell Cycle Progression but Not Cell Growth and Interacts with a Protein Having Features of CPSF-100
Zbigniew Dominski, Xiao-cui Yang, Matthew Purdy, Eric J. Wagner, William F. Marzluff
Mol Cell Biol. 2005 Feb; 25(4): 1489–1500. doi: 10.1128/MCB.25.4.1489-1500.2005
PMCID:
PMC548002
AbstractArticlePDF–487K
7.
Inositol hexakisphosphate is required for Integrator function
Min-Han Lin, Madeline K. Jensen, Nathan D. Elrod, Kai-Lieh Huang, Kevin A. Welle, Eric J. Wagner, Liang Tong
Nat Commun. 2022; 13: 5742. Published online 2022 Sep 30. doi: 10.1038/s41467-022-33506-3
PMCID:
PMC9525679
AbstractArticlePDF–2.7M
8.
IL-1 transcriptional responses to LPS are regulated by a complex of RNA-binding proteins
Lihua Shi, Li Song, Kelly Maurer, Ying Dou, Vishesh R. Patel, Chun Su, Michelle E. Leonard, Sumei Lu, Kenyaita M. Hodge, Annabel Torres, Alessandra Chesi, Struan F.A. Grant, Andrew D. Wells, Zhe Zhang, Michelle A. Petri, Kathleen E. Sullivan
J Immunol. Author manuscript; available in PMC 2021 Mar 1.
Published in final edited form as: J Immunol. 2020 Mar 1; 204(5): 1334–1344. Published online 2020 Jan 17. doi: 10.4049/jimmunol.1900650
PMCID:
PMC7033021
AbstractArticlePDF–1.0M
9.
Structure of the catalytic core of the Integrator complex
Moritz M. Pfleiderer, Wojciech P. Galej
Mol Cell. 2021 Mar 18; 81(6): 1246–1259.e8. doi: 10.1016/j.molcel.2021.01.005
PMCID:
PMC7980224
AbstractArticle
10.
The Human Integrator Complex Facilitates Transcriptional Elongation by Endonucleolytic Cleavage of Nascent Transcripts
Felipe Beckedorff, Ezra Blumenthal, Lucas Ferreira daSilva, Yuki Aoi, Pradeep Reddy Cingaram, Jingyin Yue, Anda Zhang, Sadat Dokaneheifard, Monica Guiselle Valencia, Gabriel Gaidosh, Ali Shilatifard, Ramin Shiekhattar
Cell Rep. Author manuscript; available in PMC 2020 Aug 14.
Published in final edited form as: Cell Rep. 2020 Jul 21; 32(3): 107917. doi: 10.1016/j.celrep.2020.107917
PMCID:
PMC7427568
AbstractArticlePDF–2.8M
11.
INTS10–INTS13–INTS14 form a functional module of Integrator that binds nucleic acids and the cleavage module
Kevin Sabath, Melanie L. Stäubli, Sabrina Marti, Alexander Leitner, Murielle Moes, Stefanie Jonas
Nat Commun. 2020; 11: 3422. Published online 2020 Jul 9. doi: 10.1038/s41467-020-17232-2
PMCID:
PMC7347597
AbstractArticlePDF–2.5M
12.
Integrator subunit 4 is a ‘Symplekin-like’ scaffold that associates with INTS9/11 to form the Integrator cleavage module
Todd R Albrecht, Sergey P Shevtsov, Yixuan Wu, Lauren G Mascibroda, Natoya J Peart, Kai-Lieh Huang, Iain A Sawyer, Liang Tong, Miroslav Dundr, Eric J Wagner
Nucleic Acids Res. 2018 May 4; 46(8): 4241–4255. Published online 2018 Feb 20. doi: 10.1093/nar/gky100
PMCID:
PMC5934644
AbstractArticlePDF–9.0M
13.
Nuclear-localized Asunder regulates cytoplasmic dynein localization via its role in the Integrator complex
Jeanne N. Jodoin, Poojitha Sitaram, Todd R. Albrecht, Sarah B. May, Mohammad Shboul, Ethan Lee, Bruno Reversade, Eric J. Wagner, Laura A. Lee
Mol Biol Cell. 2013 Sep 15; 24(18): 2954–2965. doi: 10.1091/mbc.E13-05-0254
PMCID:
PMC3771956
AbstractArticlePDF–2.0M
14.
The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer
Stephin J. Vervoort, Sarah A. Welsh, Jennifer R. Devlin, Elisa Barbieri, Deborah A. Knight, Sarah Offley, Stefan Bjelosevic, Matteo Costacurta, Izabela Todorovski, Conor J. Kearney, Jarrod J. Sandow, Zheng Fan, Benjamin Blyth, Victoria McLeod, Joseph H.A. Vissers, Karolina Pavic, Ben P. Martin, Gareth Gregory, Elena Demosthenous, Magnus Zethoven, Isabella Y. Kong, Edwin D. Hawkins, Simon J. Hogg, Madison J. Kelly, Andrea Newbold, Kaylene J. Simpson, Otto Kauko, Kieran F. Harvey, Michael Ohlmeyer, Jukka Westermarck, Nathanael Gray, Alessandro Gardini, Ricky W. Johnstone
Cell. Author manuscript; available in PMC 2022 Jun 10.
Published in final edited form as: Cell. 2021 Jun 10; 184(12): 3143–3162.e32. Published online 2021 May 17. doi: 10.1016/j.cell.2021.04.022
PMCID:
PMC8567840
AbstractArticlePDF–2.8M
15.
Streamlined analysis schema for high-throughput identification of endogenous protein complexes
Anna Malovannaya, Yehua Li, Yaroslava Bulynko, Sung Yun Jung, Yi Wang, Rainer B. Lanz, Bert W. O’Malley, Jun Qin
Proc Natl Acad Sci U S A. 2010 Feb 9; 107(6): 2431–2436. Published online 2010 Jan 22. doi: 10.1073/pnas.0912599106
Correction in:
Proc Natl Acad Sci U S A. 2010 Mar 30; 107(13): 6118.
PMCID:
PMC2823922
AbstractArticlePDF–566K
16.
The SOX2-Interactome in Brain Cancer Cells Identifies the Requirement of MSI2 and USP9X for the Growth of Brain Tumor Cells
Jesse L. Cox, Phillip J. Wilder, Joshua M. Gilmore, Erin L. Wuebben, Michael P. Washburn, Angie Rizzino
PLoS One. 2013; 8(5): e62857. Published online 2013 May 7. doi: 10.1371/journal.pone.0062857
PMCID:
PMC3647065
AbstractArticlePDF–5.0M
17.
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease
Luke Jostins, Stephan Ripke, Rinse K Weersma, Richard H Duerr, Dermot P McGovern, Ken Y Hui, James C Lee, L Philip Schumm, Yashoda Sharma, Carl A Anderson, Jonah Essers, Mitja Mitrovic, Kaida Ning, Isabelle Cleynen, Emilie Theatre, Sarah L Spain, Soumya Raychaudhuri, Philippe Goyette, Zhi Wei, Clara Abraham, Jean-Paul Achkar, Tariq Ahmad, Leila Amininejad, Ashwin N Ananthakrishnan, Vibeke Andersen, Jane M Andrews, Leonard Baidoo, Tobias Balschun, Peter A Bampton, Alain Bitton, Gabrielle Boucher, Stephan Brand, Carsten Büning, Ariella Cohain, Sven Cichon, Mauro D’Amato, Dirk De Jong, Kathy L Devaney, Marla Dubinsky, Cathryn Edwards, David Ellinghaus, Lynnette R Ferguson, Denis Franchimont, Karin Fransen, Richard Gearry, Michel Georges, Christian Gieger, Jürgen Glas, Talin Haritunians, Ailsa Hart, Chris Hawkey, Matija Hedl, Xinli Hu, Tom H Karlsen, Limas Kupcinskas, Subra Kugathasan, Anna Latiano, Debby Laukens, Ian C Lawrance, Charlie W Lees, Edouard Louis, Gillian Mahy, John Mansfield, Angharad R Morgan, Craig Mowat, William Newman, Orazio Palmieri, Cyriel Y Ponsioen, Uros Potocnik, Natalie J Prescott, Miguel Regueiro, Jerome I Rotter, Richard K Russell, Jeremy D Sanderson, Miquel Sans, Jack Satsangi, Stefan Schreiber, Lisa A Simms, Jurgita Sventoraityte, Stephan R Targan, Kent D Taylor, Mark Tremelling, Hein W Verspaget, Martine De Vos, Cisca Wijmenga, David C Wilson, Juliane Winkelmann, Ramnik J Xavier, Sebastian Zeissig, Bin Zhang, Clarence K Zhang, Hongyu Zhao, The International IBD Genetics Consortium, Mark S Silverberg, Vito Annese, Hakon Hakonarson, Steven R Brant, Graham Radford-Smith, Christopher G Mathew, John D Rioux, Eric E Schadt, Mark J Daly, Andre Franke, Miles Parkes, Severine Vermeire, Jeffrey C Barrett, Judy H Cho
Nature. Author manuscript; available in PMC 2013 May 1.
Published in final edited form as: Nature. 2012 Nov 1; 491(7422): 119–124. doi: 10.1038/nature11582
PMCID:
PMC3491803
AbstractArticlePDF–706K
18.
The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin
Dragomir B. Krastev, Shudong Li, Yilun Sun, Andrew J. Wicks, Gwendoline Hoslett, Daniel Weekes, Luned M. Badder, Eleanor G. Knight, Rebecca Marlow, Mercedes Calvo Pardo, Lu Yu, Tanaji T. Talele, Jiri Bartek, Jyoti S. Choudhary, Yves Pommier, Stephen J. Pettitt, Andrew N. J. Tutt, Kristijan Ramadan, Christopher J. Lord
Nat Cell Biol. 2022; 24(1): 62–73. Published online 2022 Jan 10. doi: 10.1038/s41556-021-00807-6
PMCID:
PMC8760077
AbstractArticlePDF–12M
19.
New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing
Fernanda Luisa Basei, Gabriela Vaz Meirelles, Germanna Lima Righetto, Deivid Lucas dos Santos Migueleti, Juliana Helena Costa Smetana, Jörg Kobarg
Proteome Sci. 2015; 13: 11. Published online 2015 Feb 26. doi: 10.1186/s12953-015-0065-6
PMCID:
PMC4367857
AbstractArticlePDF–3.1M
20.
KAP1 facilitates reinstatement of heterochromatin after DNA replication
Suk Min Jang, Annamaria Kauzlaric, Jean-Pierre Quivy, Julien Pontis, Benjamin Rauwel, Andrea Coluccio, Sandra Offner, Julien Duc, Priscilla Turelli, Geneviève Almouzni, Didier Trono
Nucleic Acids Res. 2018 Sep 28; 46(17): 8788–8802. Published online 2018 Jun 28. doi: 10.1093/nar/gky580
PMCID:
PMC6158507
AbstractArticlePDF–9.4M

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Filter your results:

Find related data

Recent activity

Clear Turn Off Turn On

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
You are here: NCBI > Literature > PubMed Central (PMC)
Support Center