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Select item 105169001.

Structural and functional characterization of USP47 reveals a hot spot for inhibitor design

Sang Chul Shin, Jinyoung Park, Kyung Hee Kim, Jung Min Yoon, Jinhong Cho, Byung Hak Ha, Yeonji Oh, Hyunah Choo, Eun Joo Song, Eunice EunKyeong Kim

Commun Biol. 2023; 6: 970. Published online 2023 Sep 22. doi: 10.1038/s42003-023-05345-5

PMCID:: PMC10516900

Abstract Article PDF–2.7M

Select item 88222872.

USP47 stabilizes BACH1 to promote the Warburg effect and non-small cell lung cancer development via stimulating Hk2 and Gapdh transcription

Jing Peng, Wencan Li, Nianxi Tan, Xihua Lai, Weilin Jiang, Guang Chen

Am J Cancer Res. 2022; 12(1): 91–107. Published online 2022 Jan 15.

PMCID:: PMC8822287

Abstract Article PDF–3.8M

Select item 84952433.

USP47-Mediated Deubiquitination and Stabilization of TCEA3 Attenuates Pyroptosis and Apoptosis of Colorectal Cancer Cells Induced by Chemotherapeutic Doxorubicin

Xiaodan Hou, Jun Xia, Yuan Feng, Long Cui, Yili Yang, Peng Yang, Xin Xu

Front Pharmacol. 2021; 12: 713322. Published online 2021 Sep 23. doi: 10.3389/fphar.2021.713322

PMCID:: PMC8495243

Abstract Article PDF–2.1M

Select item 69548884.

USP47-mediated deubiquitination and stabilization of YAP contributes to the progression of colorectal cancer

Beiqing Pan, Yi Yang, Jian Li, Yu Wang, Chuantao Fang, Fa-Xing Yu, Yanhui Xu

Protein Cell. 2020 Feb; 11(2): 138–143. Published online 2019 Nov 20. doi: 10.1007/s13238-019-00674-w

PMCID:: PMC6954888

Article PDF–1.8M

Select item 88701435.

MicroRNA-101-3p Suppresses Cancer Cell Growth by Inhibiting the USP47-Induced Deubiquitination of RPL11

Jinyoung Park, Moonsoo Cho, Jinhong Cho, Eunice EunKyeong Kim, Eun Joo Song

Cancers (Basel) 2022 Feb; 14(4): 964. Published online 2022 Feb 15. doi: 10.3390/cancers14040964

PMCID:: PMC8870143

Abstract Article PDF–5.4M

Select item 72813216.

USP47 Promotes Tumorigenesis by Negative Regulation of p53 through Deubiquitinating Ribosomal Protein S2

Jinhong Cho, Jinyoung Park, Sang Chul Shin, Mihue Jang, Jae-Hong Kim, Eunice EunKyeong Kim, Eun Joo Song

Cancers (Basel) 2020 May; 12(5): 1137. Published online 2020 May 1. doi: 10.3390/cancers12051137

PMCID:: PMC7281321

Abstract Article PDF–5.1M

Select item 61724587.

USP7 and USP47 deubiquitinases regulate NLRP3 inflammasome activation

Pablo Palazón‐Riquelme, Jonathan D Worboys, Jack Green, Ana Valera, Fatima Martín‐Sánchez, Carolina Pellegrini, David Brough, Gloria López‐Castejón

EMBO Rep. 2018 Oct; 19(10): e44766. Published online 2018 Sep 11. doi: 10.15252/embr.201744766

PMCID:: PMC6172458

Abstract Article PDF–1.1M

Select item 56983338.

Hypoxia induces epithelial-mesenchymal transition in colorectal cancer cells through ubiquitin-specific protease 47-mediated stabilization of Snail: A potential role of Sox9

Bae-Jung Choi, Sin-Aye Park, Sung-Young Lee, Young Nam Cha, Young-Joon Surh

Sci Rep. 2017; 7: 15918. Published online 2017 Nov 21. doi: 10.1038/s41598-017-15139-5

PMCID:: PMC5698333

Abstract Article PDF–11M

Select item 42441959.

Minus end–directed motor KIFC3 suppresses E-cadherin degradation by recruiting USP47 to adherens junctions

Kyoko Sako-Kubota, Nobutoshi Tanaka, Shigenori Nagae, Wenxiang Meng, Masatoshi Takeichi

Mol Biol Cell. 2014 Dec 1; 25(24): 3851–3860. doi: 10.1091/mbc.E14-07-1245

PMCID:: PMC4244195

Abstract Article PDF–1.9M

Select item 778255310.

Targeting USP47 overcomes tyrosine kinase inhibitor resistance and eradicates leukemia stem/progenitor cells in chronic myelogenous leukemia

Hu Lei, Han-Zhang Xu, Hui-Zhuang Shan, Meng Liu, Ying Lu, Zhi-Xiao Fang, Jin Jin, Bo Jing, Xin-Hua Xiao, Shen-Meng Gao, Feng-Hou Gao, Li Xia, Li Yang, Li-Gen Liu, Wei-Wei Wang, Chuan-Xu Liu, Yin Tong, Yun-Zhao Wu, Jun-Ke Zheng, Guo-Qiang Chen, Li Zhou, Ying-Li Wu

Nat Commun. 2021; 12: 51. Published online 2021 Jan 4. doi: 10.1038/s41467-020-20259-0

PMCID:: PMC7782553

Abstract Article PDF–5.4M

Select item 719852511.

Deubiquitinase USP47-stabilized splicing factor IK regulates the splicing of ATM pre-mRNA

Hye In Ka, Sunyi Lee, Sora Han, Ae Lee Jeong, Ji Young Park, Hyun Jeong Joo, Su Jung Soh, Doyeon Park, Young Yang

Cell Death Discov. 2020; 6: 34. Published online 2020 May 4. doi: 10.1038/s41420-020-0268-1

PMCID:: PMC7198525

Abstract Article PDF–2.1M

Select item 456172712.

Deubiquitinase USP47/UBP64E Regulates β-Catenin Ubiquitination and Degradation and Plays a Positive Role in Wnt Signaling

Jiandang Shi, Yajuan Liu, Xuehe Xu, Wen Zhang, Tianxin Yu, Jianhang Jia, Chunming Liu

Mol Cell Biol. 2015 Oct; 35(19): 3301–3311. Prepublished online 2015 Jul 13. Published online 2015 Sep 4. doi: 10.1128/MCB.00373-15

PMCID:: PMC4561727

Abstract Article PDF–2.2M

Select item 1068898913.

USP47 inhibits m⁶A-dependent c-Myc translation to maintain regulatory T cell metabolic and functional homeostasis

Aiting Wang, Haiyan Huang, Jian-Hong Shi, Xiaoyan Yu, Rui Ding, Yuerong Zhang, Qiaoqiao Han, Zhi-Yu Ni, Xia Li, Ren Zhao, Qiang Zou

J Clin Invest. 2023 Dec 1; 133(23): e169365. Published online 2023 Dec 1. doi: 10.1172/JCI169365

PMCID:: PMC10688989

Abstract Article PDF–2.8M

Select item 1015811414.

USP36 promotes tumorigenesis and drug sensitivity of glioblastoma by deubiquitinating and stabilizing ALKBH5

Guoqiang Chang, Gloria S Xie, Li Ma, Linlin Li, Hope T Richard

Neuro Oncol. 2023 May; 25(5): 841–853. Published online 2022 Oct 14. doi: 10.1093/neuonc/noac238

Correction in:: Neuro Oncol. 2023 Oct; 25(10): 1913.

PMCID:: PMC10158114

Abstract Article PDF–7.9M

Select item 1003820115.

USP47 deubiquitylates Groucho/TLE to Promote Wnt-β-catenin Signaling

Sara Kassel, Alison J. Hanson, Hassina Benchabane, Kenyi Saito-Diaz, Carly R. Cabel, Lily Goldsmith, Muhammad Taha, Aksheta Kanuganti, Victoria H. Ng, George Xu, Fei Ye, Julia Picker, Fillip Port, Michael Boutros, Vivian L. Weiss, David J. Robbins, Curtis A. Thorne, Yashi Ahmed, Ethan Lee

Sci Signal. Author manuscript; available in PMC 2023 Aug 7.

Published in final edited form as: Sci Signal. 2023 Feb 7; 16(771): eabn8372. Published online 2023 Feb 7. doi: 10.1126/scisignal.abn8372

PMCID:: PMC10038201

Abstract Article PDF–1.6M

Select item 386978616.

The ubiquitin-specific protease USP47 is a novel β-TRCP interactor regulating cell survival

A Peschiaroli, JR Skaar, M Pagano, G Melino

Oncogene. Author manuscript; available in PMC 2013 Dec 20.

Published in final edited form as: Oncogene. 2010 Mar 4; 29(9): 10.1038/onc.2009.430. Published online 2009 Dec 7. doi: 10.1038/onc.2009.430

PMCID:: PMC3869786

Abstract Article PDF–2.0M

Select item 603481717.

CHIP E3 ligase mediates proteasomal degradation of the proliferation regulatory protein ALDH1L1 during the transition of NIH3T3 fibroblasts from G₀/G₁ to S-phase

Qasim A. Khan, Peter Pediaditakis, Yuryi Malakhau, Amin Esmaeilniakooshkghazi, Zahra Ashkavand, Valentin Sereda, Natalia I. Krupenko, Sergey A. Krupenko

PLoS One. 2018; 13(7): e0199699. Published online 2018 Jul 6. doi: 10.1371/journal.pone.0199699

PMCID:: PMC6034817

Abstract Article PDF–6.4M

Select item 599587018.

SKP2- and OTUD1-regulated non-proteolytic ubiquitination of YAP promotes YAP nuclear localization and activity

Fan Yao, Zhicheng Zhou, Jongchan Kim, Qinglei Hang, Zhenna Xiao, Baochau N. Ton, Liang Chang, Na Liu, Liyong Zeng, Wenqi Wang, Yumeng Wang, Peijing Zhang, Xiaoyu Hu, Xiaohua Su, Han Liang, Yutong Sun, Li Ma

Nat Commun. 2018; 9: 2269. Published online 2018 Jun 11. doi: 10.1038/s41467-018-04620-y

PMCID:: PMC5995870

Abstract Article PDF–7.5M

Select item 446986619.

USP47 and C Terminus of Hsp70-Interacting Protein (CHIP) Antagonistically Regulate Katanin-p60-Mediated Axonal Growth

Seung Wook Yang, Kyu Hee Oh, Esther Park, Hyun Min Chang, Jung Mi Park, Min Woo Seong, Seung Hyeun Ka, Woo Keun Song, Dong Eun Park, Peter W. Baas, Young Joo Jeon, Chin Ha Chung

J Neurosci. 2013 Jul 31; 33(31): 12728–12738. doi: 10.1523/JNEUROSCI.0698-13.2013

PMCID:: PMC4469866

Abstract Article PDF–4.7M

Select item 322929920.

mTOR drives its own activation via SCF^β-TRCP-dependent degradation of the mTOR inhibitor DEPTOR

Daming Gao, Hiroyuki Inuzuka, Meng-Kwang Marcus Tan, Hidefumi Fukushima, Jason W. Locasale, Pengda Liu, Lixin Wan, Bo Zhai, Y. Rebecca Chin, Shavali Shaik, Costas A. Lyssiotis, Steven P. Gygi, Alex Toker, Lewis C. Cantley, John M. Asara, J. Wade Harper, Wenyi Wei

Mol Cell. Author manuscript; available in PMC 2012 Oct 21.

Published in final edited form as: Mol Cell. 2011 Oct 21; 44(2): 290–303. doi: 10.1016/j.molcel.2011.08.030