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Select item 58154311.

Perturbation of RNA Polymerase I transcription machinery by ablation of HEATR1 triggers the RPL5/RPL11-MDM2-p53 ribosome biogenesis stress checkpoint pathway in human cells

Zsofia Turi, Marketa Senkyrikova, Martin Mistrik, Jiri Bartek, Pavel Moudry

Cell Cycle. 2018; 17(1): 92–101. Published online 2017 Dec 10. doi: 10.1080/15384101.2017.1403685

PMCID:: PMC5815431

Abstract Article PDF–1.0M

Select item 68887472.

HEATR1 deficiency promotes pancreatic cancer proliferation and gemcitabine resistance by up-regulating Nrf2 signaling

Yunjiang Zhou, Keke Wang, Yang Zhou, Tao Li, Mengdi Yang, Rui Wang, Yaxin Chen, Mengran Cao, Rong Hu

Redox Biol. 2020 Jan; 29: 101390. Published online 2019 Nov 20. doi: 10.1016/j.redox.2019.101390

PMCID:: PMC6888747

Abstract Article PDF–6.9M

Select item 41210973.

Glioma-Associated Antigen HEATR1 Induces Functional Cytotoxic T Lymphocytes in Patients with Glioma

Zhe Bao Wu, Chao Qiu, An Li Zhang, Lin Cai, Shao Jian Lin, Yu Yao, Qi Sheng Tang, Ming Xu, Wei Hua, Yi Wei Chu, Ying Mao, Jian Hong Zhu, Jianqing Xu, Liang Fu Zhou

J Immunol Res. 2014; 2014: 131494. Published online 2014 Jul 9. doi: 10.1155/2014/131494

PMCID:: PMC4121097

Abstract Article PDF–1.0M

Select item 108971694.

Ribogenesis boosts controlled by HEATR1-MYC interplay promote transition into brain tumour growth

Laura R Diaz, Jon Gil-Ranedo, Karolina J Jaworek, Nsikan Nsek, Joao Pinheiro Marques, Eleni Costa, David A Hilton, Hubert Bieluczyk, Oliver Warrington, C Oliver Hanemann, Matthias E Futschik, Torsten Bossing, Claudia S Barros

EMBO Rep. 2024 Jan; 25(1): 168–197. Published online 2024 Jan 15. doi: 10.1038/s44319-023-00017-1

PMCID:: PMC10897169

Abstract Article PDF–23M

Select item 19488595.

Recruitment of factors linking transcription and processing of pre-rRNA to NOR chromatin is UBF-dependent and occurs independent of transcription in human cells

José-Luis Prieto, Brian McStay

Genes Dev. 2007 Aug 15; 21(16): 2041–2054. doi: 10.1101/gad.436707

PMCID:: PMC1948859

Abstract Article PDF–881K

Select item 70619826.

KAP1 targets actively transcribed genomic loci to exert pleomorphic effects on RNA polymerase II activity

Annamaria Kauzlaric, Suk Min Jang, Mehdi Morchikh, Marco Cassano, Evarist Planet, Monsef Benkirane, Didier Trono

Philos Trans R Soc Lond B Biol Sci. 2020 Mar 30; 375(1795): 20190334. Published online 2020 Feb 10. doi: 10.1098/rstb.2019.0334

PMCID:: PMC7061982

Abstract Article PDF–1.0M

Select item 87444647.

Nucleolar maturation of the human small subunit processome

Sameer Singh, Arnaud Vanden Broeck, Linamarie Miller, Malik Chaker-Margot, Sebastian Klinge

Science. Author manuscript; available in PMC 2022 Sep 10.

Published in final edited form as: Science. 2021 Sep 10; 373(6560): eabj5338. Published online 2021 Sep 10. doi: 10.1126/science.abj5338

PMCID:: PMC8744464

Abstract Article PDF–3.6M

Select item 75895248.

Targeting SKA3 suppresses the proliferation and chemoresistance of laryngeal squamous cell carcinoma via impairing PLK1–AKT axis-mediated glycolysis

Wei Gao, Yuliang Zhang, Hongjie Luo, Min Niu, Xiwang Zheng, Wanglai Hu, Jiajia Cui, Xuting Xue, Yunfeng Bo, Fengsheng Dai, Yan Lu, Dongli Yang, Yujia Guo, Huina Guo, Huizheng Li, Yu Zhang, Tao Yang, Li Li, Linshi Zhang, Rui Hou, Shuxin Wen, Changming An, Teng Ma, Lei Jin, Wei Xu, Yongyan Wu

Cell Death Dis. 2020 Oct; 11(10): 919. Published online 2020 Oct 26. doi: 10.1038/s41419-020-03104-6

PMCID:: PMC7589524

Abstract Article PDF–5.2M

Select item 64366169.

PPARγ Interaction with UBR5/ATMIN Promotes DNA Repairto Maintain Endothelial Homeostasis

Caiyun G. Li, Cathal Mahon, Nathaly M. Sweeney, Erik Verschueren, Vivek Kantamani, Dan Li, Jan K. Hennigs, David P. Marciano, Isabel Diebold, Ossama Abu-Halawa, Matthew Elliott, Silin Sa, Feng Guo, Lingli Wang, Aiqin Cao, Christophe Guignabert, Julie Sollier, Nils P. Nickel, Mark Kaschwich, Karlene A. Cimprich, Marlene Rabinovitch

Cell Rep. Author manuscript; available in PMC 2019 Mar 27.

Published in final edited form as: Cell Rep. 2019 Jan 29; 26(5): 1333–1343.e7. doi: 10.1016/j.celrep.2019.01.013

PMCID:: PMC6436616

Abstract Article PDF–1.9M

Select item 13361710.

Functional Proteomic Analysis of Human Nucleolus

Alexander Scherl, Yohann Couté, Catherine Déon, Aleth Callé, Karine Kindbeiter, Jean-Charles Sanchez, Anna Greco, Denis Hochstrasser, Jean-Jacques Diaz

Mol Biol Cell. 2002 Nov; 13(11): 4100–4109. doi: 10.1091/mbc.E02-05-0271

PMCID:: PMC133617

Abstract Article PDF–369K

Select item 624272711.

Stasimon/Tmem41b localizes to mitochondria-associated ER membranes and is essential for mouse embryonic development

Meaghan Van Alstyne, Francesco Lotti, Andrea Dal Mas, Estela Area Gomez, Livio Pellizzoni

Biochem Biophys Res Commun. Author manuscript; available in PMC 2019 Nov 30.

Published in final edited form as: Biochem Biophys Res Commun. 2018 Nov 30; 506(3): 463–470. Published online 2018 Oct 22. doi: 10.1016/j.bbrc.2018.10.073

PMCID:: PMC6242727

Abstract Article PDF–910K

Select item 495798112.

The TIP60 complex is a conserved coactivator of HIF1A

Joel I. Perez-Perri, Veronica L. Dengler, K. Audrey Audetat, Ahwan Pandey, Elizabeth A. Bonner, Marjeta Urh, Jacqui Mendez, Danette L. Daniels, Pablo Wappner, Matthew D. Galbraith, Joaquín M. Espinosa

Cell Rep. Author manuscript; available in PMC 2016 Jul 22.

Published in final edited form as: Cell Rep. 2016 Jun 28; 16(1): 37–47. Published online 2016 Jun 16. doi: 10.1016/j.celrep.2016.05.082

PMCID:: PMC4957981

Abstract Article PDF–1.5M

Select item 666750013.

A protein-RNA interaction atlas of the ribosome biogenesis factor AATF

Rainer W. J. Kaiser, Michael Ignarski, Eric L. Van Nostrand, Christian K. Frese, Manaswita Jain, Sadrija Cukoski, Heide Heinen, Melanie Schaechter, Lisa Seufert, Konstantin Bunte, Peter Frommolt, Patrick Keller, Mark Helm, Katrin Bohl, Martin Höhne, Bernhard Schermer, Thomas Benzing, Katja Höpker, Christoph Dieterich, Gene W. Yeo, Roman-Ulrich Müller, Francesca Fabretti

Sci Rep. 2019; 9: 11071. Published online 2019 Jul 30. doi: 10.1038/s41598-019-47552-3

PMCID:: PMC6667500

Abstract Article PDF–2.8M

Select item 397730514.

RSPO–LGR4 functions via IQGAP1 to potentiate Wnt signaling

Kendra S. Carmon, Xing Gong, Jing Yi, Anthony Thomas, Qingyun Liu

Proc Natl Acad Sci U S A. 2014 Apr 1; 111(13): E1221–E1229. Published online 2014 Mar 17. doi: 10.1073/pnas.1323106111

PMCID:: PMC3977305

Abstract Article PDF–1.7M

Select item 808827415.

The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch

Agnieszka T. Kawashima, Cassandra Wong, Gema Lordén, Charles C. King, Pablo Lara-Gonzalez, Arshad Desai, Anne-Claude Gingras, Alexandra C. Newton

Mol Cell Biol. 2021 Mar; 41(3): e00333-20. Prepublished online 2021 Jan 4. Published online 2021 Feb 23. doi: 10.1128/MCB.00333-20

PMCID:: PMC8088274

Abstract Article PDF–3.1M

Select item 631799416.

SNIP1 Recruits TET2 to Regulate c-MYC Target Genes and Cellular DNA Damage Response

Lei-Lei Chen, Huai-Peng Lin, Wen-Jie Zhou, Chen-Xi He, Zhi-Yong Zhang, Zhou-Li Cheng, Jun-Bin Song, Peng Liu, Xin-Yu Chen, Yu-Kun Xia, Xiu-Fei Chen, Ren-Qiang Sun, Jing-Ye Zhang, Yi-Ping Sun, Lei Song, Bing-Jie Liu, Rui-Kai Du, Chen Ding, Fei Lan, Sheng-Lin Huang, Feng Zhou, Suling Liu, Yue Xiong, Dan Ye, Kun-Liang Guan

Cell Rep. Author manuscript; available in PMC 2019 Jan 3.

Published in final edited form as: Cell Rep. 2018 Nov 6; 25(6): 1485–1500.e4. doi: 10.1016/j.celrep.2018.10.028