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Select item 78401271.

NOTCH1-driven UBR7 stimulates nucleotide biosynthesis to promote T cell acute lymphoblastic leukemia

Shashank Srivastava, Umakant Sahu, Yalu Zhou, Ann K. Hogan, Kizhakke Mattada Sathyan, Justin Bodner, Jiehuan Huang, Kelvin A. Wong, Natalia Khalatyan, Jeffrey N. Savas, Panagiotis Ntziachristos, Issam Ben-Sahra, Daniel R. Foltz

Sci Adv. 2021 Jan; 7(5): eabc9781. Published online 2021 Jan 27. doi: 10.1126/sciadv.abc9781

PMCID:: PMC7840127

Article PDF–6.9M

Select item 78207262.

UBR7 functions with UBR5 in the Notch signaling pathway and is involved in a neurodevelopmental syndrome with epilepsy, ptosis, and hypothyroidism

Chunmei Li, Eliane Beauregard-Lacroix, Christine Kondratev, Justine Rousseau, Ah Jung Heo, Katherine Neas, Brett H. Graham, Jill A. Rosenfeld, Carlos A. Bacino, Matias Wagner, Maren Wenzel, Fuad Al Mutairi, Hamad Al Deiab, Joseph G. Gleeson, Valentina Stanley, Maha S. Zaki, Yong Tae Kwon, Michel R. Leroux, Philippe M. Campeau

Am J Hum Genet. 2021 Jan 7; 108(1): 134–147. Published online 2020 Dec 18. doi: 10.1016/j.ajhg.2020.11.018

PMCID:: PMC7820726

Article PDF–4.1M

Select item 22241663.

Synthetic heterovalent inhibitors targeting recognition E3 components of the N-end rule pathway

Min Jae Lee, Krishnendu Pal, Takafumi Tasaki, Sayantani Roy, Yonghua Jiang, Jee Young An, Rajkumar Banerjee, Yong Tae Kwon

Proc Natl Acad Sci U S A. 2008 Jan 8; 105(1): 100–105. Published online 2007 Dec 27. doi: 10.1073/pnas.0708465105

PMCID:: PMC2224166

Article PDF–1.2M

Select item 64389844.

Atypical plant homeodomain of UBR7 functions as an H2BK120Ub ligase and breast tumor suppressor

Santanu Adhikary, Deepavali Chakravarti, Christopher Terranova, Isha Sengupta, Mayinuer Maitituoheti, Anirban Dasgupta, Dushyant Kumar Srivastava, Junsheng Ma, Ayush T. Raman, Emily Tarco, Aysegul A. Sahin, Roland Bassett, Fei Yang, Coya Tapia, Siddhartha Roy, Kunal Rai, Chandrima Das

Nat Commun. 2019; 10: 1398. Published online 2019 Mar 28. doi: 10.1038/s41467-019-08986-5

PMCID:: PMC6438984

Article PDF–3.4M

Select item 86721815.

UBR7 acts as a histone chaperone for post‐nucleosomal histone H3

Ann K Hogan, Kizhakke M Sathyan, Alexander B Willis, Sakshi Khurana, Shashank Srivastava, Ewelina Zasadzińska, Alexander S Lee, Aaron O Bailey, Matthew N Gaynes, Jiehuan Huang, Justin Bodner, Celeste D Rosencrance, Kelvin A Wong, Marc A Morgan, Kyle P Eagen, Ali Shilatifard, Daniel R Foltz

EMBO J. 2021 Dec 15; 40(24): e108307. Published online 2021 Nov 17. doi: 10.15252/embj.2021108307

PMCID:: PMC8672181

Article PDF–3.8M

Select item 57759146.

A chemical proteomics approach to reveal direct protein-protein interactions in living cells

Ralph E. Kleiner, Lisa E. Hang, Kelly R. Molloy, Brian T. Chait, Tarun M. Kapoor

Cell Chem Biol. Author manuscript; available in PMC 2019 Jan 18.

Published in final edited form as: Cell Chem Biol. 2018 Jan 18; 25(1): 110–120.e3. Published online 2017 Nov 5. doi: 10.1016/j.chembiol.2017.10.001

PMCID:: PMC5775914

Article PDF–2.1M

Select item 27473667.

Centromere specific assembly of CENP-A nucleosomes is mediated by HJURP

Daniel R. Foltz, Lars E.T. Jansen, Aaron O. Bailey, John R. Yates, III, Emily A. Bassett, Stacey Wood, Ben E. Black, Don W. Cleveland

Cell. Author manuscript; available in PMC 2010 May 1.

Published in final edited form as: Cell. 2009 May 1; 137(3): 472–484. doi: 10.1016/j.cell.2009.02.039

PMCID:: PMC2747366

Article PDF–2.3M

Select item 41939228.

Autoubiquitination of the 26S Proteasome on Rpn13 Regulates Breakdown of Ubiquitin Conjugates

Henrike C Besche, Zhe Sha, Nikolay V Kukushkin, Andreas Peth, Eva-Maria Hock, Woong Kim, Steven Gygi, Juan A Gutierrez, Hua Liao, Lawrence Dick, Alfred L Goldberg

EMBO J. 2014 May 16; 33(10): 1159–1176. Published online 2014 May 8. doi: 10.1002/embj.201386906

PMCID:: PMC4193922

Article PDF–1.1M

Select item 46561089.

Analysis of the Histone H3.1 Interactome: A Suitable Chaperone for the Right Event

Eric I. Campos, Arne H. Smits, Young-Hoon Kang, Sébastien Landry, Thelma M. Escobar, Shruti Nayak, Beatrix M. Ueberheide, Daniel Durocher, Michiel Vermeulen, Jerard Hurwitz, Danny Reinberg

Mol Cell. Author manuscript; available in PMC 2016 Nov 19.

Published in final edited form as: Mol Cell. 2015 Nov 19; 60(4): 697–709. Published online 2015 Oct 29. doi: 10.1016/j.molcel.2015.08.005

PMCID:: PMC4656108

Article PDF–1.0M

Select item 584026610.

Insights into the ubiquitin-proteasome system of human embryonic stem cells

Isabel Saez, Seda Koyuncu, Ricardo Gutierrez-Garcia, Christoph Dieterich, David Vilchez

Sci Rep. 2018; 8: 4092. Published online 2018 Mar 6. doi: 10.1038/s41598-018-22384-9

PMCID:: PMC5840266

Article PDF–2.9M

Select item 954034511.

The in vivo Interaction Landscape of Histones H3.1 and H3.3

Robert Siddaway, Scott Milos, Étienne Coyaud, Hwa Young Yun, Shahir M. Morcos, Sanja Pajovic, Eric I. Campos, Brian Raught, Cynthia Hawkins

Mol Cell Proteomics. 2022 Oct; 21(10): 100411. Published online 2022 Sep 9. doi: 10.1016/j.mcpro.2022.100411

PMCID:: PMC9540345

Article PDF–3.9M

Select item 438371312.

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes

Jean-Philippe Lambert, Monika Tucholska, Christopher Go, James D.R. Knight, Anne-Claude Gingras

J Proteomics. Author manuscript; available in PMC 2016 Apr 6.

Published in final edited form as: J Proteomics. 2015 Apr 6; 118: 81–94. Published online 2014 Oct 2. doi: 10.1016/j.jprot.2014.09.011

PMCID:: PMC4383713

Article PDF–1.4M

Select item 607772213.

Estrogen-regulated feedback loop limits the efficacy of estrogen receptor–targeted breast cancer therapy

Tengfei Xiao, Wei Li, Xiaoqing Wang, Han Xu, Jixin Yang, Qiu Wu, Ying Huang, Joseph Geradts, Peng Jiang, Teng Fei, David Chi, Chongzhi Zang, Qi Liao, Jonathan Rennhack, Eran Andrechek, Nanlin Li, Simone Detre, Mitchell Dowsett, Rinath M. Jeselsohn, X. Shirley Liu, Myles Brown

Proc Natl Acad Sci U S A. 2018 Jul 31; 115(31): 7869–7878. Published online 2018 Jul 9. doi: 10.1073/pnas.1722617115

PMCID:: PMC6077722

Article PDF–2.4M

Select item 752544114.

Mutual regulation between OGT and XIAP to control colon cancer cell growth and invasion

Hyeon Gyu Seo, Han Byeol Kim, Ji Young Yoon, Tae Hyun Kweon, Yun Soo Park, Jingu Kang, Jinwoo Jung, SeongJin Son, Eugene C. Yi, Tae Ho Lee, Won Ho Yang, Jin Won Cho

Cell Death Dis. 2020 Sep; 11(9): 815. Published online 2020 Sep 29. doi: 10.1038/s41419-020-02999-5

PMCID:: PMC7525441

Article PDF–3.7M

Select item 395408115.

A high-throughput approach for measuring temporal changes in the interactome

Anders R. Kristensen, Joerg Gsponer, Leonard J. Foster

Nat Methods. Author manuscript; available in PMC 2014 Mar 14.

Published in final edited form as: Nat Methods. 2012 Sep; 9(9): 907–909. Published online 2012 Aug 5. doi: 10.1038/nmeth.2131

PMCID:: PMC3954081

Article PDF–632K

Select item 480585516.

Substrate-Trapped Interactors of PHD3 and FIH Cluster in Distinct Signaling Pathways

Javier Rodriguez, Ruth Pilkington, Amaya Garcia Munoz, Lan K. Nguyen, Nora Rauch, Susan Kennedy, Naser Monsefi, Ana Herrero, Cormac T. Taylor, Alex von Kriegsheim

Cell Rep. 2016 Mar 22; 14(11): 2745–2760. Published online 2016 Mar 10. doi: 10.1016/j.celrep.2016.02.043

PMCID:: PMC4805855

Article PDF–4.6M

Select item 586483217.

An AP-MS- and BioID-compatible MAC-tag enables comprehensive mapping of protein interactions and subcellular localizations

Xiaonan Liu, Kari Salokas, Fitsum Tamene, Yaming Jiu, Rigbe G. Weldatsadik, Tiina Öhman, Markku Varjosalo

Nat Commun. 2018; 9: 1188. Published online 2018 Mar 22. doi: 10.1038/s41467-018-03523-2

PMCID:: PMC5864832

Article PDF–4.5M

Select item 659455118.

PLEKHA4/kramer Attenuates Dishevelled Ubiquitination to Modulate Wnt and Planar Cell Polarity Signaling

Adnan Shami Shah, Alex G. Batrouni, Dongsung Kim, Amith Punyala, Wendy Cao, Chun Han, Michael L. Goldberg, Marcus B. Smolka, Jeremy M. Baskin

Cell Rep. Author manuscript; available in PMC 2019 Jun 26.

Published in final edited form as: Cell Rep. 2019 May 14; 27(7): 2157–2170.e8. doi: 10.1016/j.celrep.2019.04.060

PMCID:: PMC6594551

Article PDF–1.4M

Select item 347780419.

A Census of Human Soluble Protein Complexes

Pierre C. Havugimana, G. Traver Hart, Tamás Nepusz, Haixuan Yang, Andrei L. Turinsky, Zhihua Li, Peggy I. Wang, Daniel R. Boutz, Vincent Fong, Sadhna Phanse, Mohan Babu, Stephanie A. Craig, Pingzhao Hu, Cuihong Wan, James Vlasblom, Vaqaarun-Nisa Dar, Alexander Bezginov, Gregory W. Clark, Gabriel C. Wu, Shoshana J. Wodak, Elisabeth R.M. Tillier, Alberto Paccanaro, Edward M. Marcotte, Andrew Emili

Cell. Author manuscript; available in PMC 2013 Aug 31.

Published in final edited form as: Cell. 2012 Aug 31; 150(5): 1068–1081. doi: 10.1016/j.cell.2012.08.011

PMCID:: PMC3477804

Article PDF–7.7M

Select item 927928520.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Article PDF–2.5M

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