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Select item 73389931.

TROY signals through JAK1-STAT3 to promote glioblastoma cell migration and resistance

Zonghui Ding, Jean M. Kloss, Serdar Tuncali, Nhan L. Tran, Joseph C. Loftus

Neoplasia. 2020 Sep; 22(9): 352–364. Published online 2020 Jul 3. doi: 10.1016/j.neo.2020.06.005

PMCID:: PMC7338993

Abstract Article PDF–2.1M

Select item 65337202.

The inherited variations of a p53-responsive enhancer in 13q12.12 confer lung cancer risk by attenuating TNFRSF19 expression

Lipei Shao, Xianglin Zuo, Yin Yang, Yu Zhang, Nan Yang, Bin Shen, Jianying Wang, Xuchun Wang, Ruilei Li, Guangfu Jin, Dawei Yu, Yuan Chen, Luan Sun, Zhen Li, Qiaofen Fu, Zhibin Hu, Xiao Han, Xin Song, Hongbin Shen, Yujie Sun

Genome Biol. 2019; 20: 103. Published online 2019 May 24. doi: 10.1186/s13059-019-1696-1

PMCID:: PMC6533720

Abstract Article PDF–5.6M

Select item 37482533.

TROY (TNFRSF19) promotes glioblastoma cell survival signaling and therapeutic resistance

Joseph C. Loftus, Harshil Dhruv, Serdar Tuncali, Jean Kloss, Zhongbo Yang, Cassie A. Schumacher, Brian Cao, Bart O. Williams, Jennifer M. Eschbacher, Julianna T.D. Ross, Nhan L. Tran

Mol Cancer Res. Author manuscript; available in PMC 2014 Aug 1.

Published in final edited form as: Mol Cancer Res. 2013 Aug; 11(8): 865–874. Published online 2013 May 22. doi: 10.1158/1541-7786.MCR-13-0008

PMCID:: PMC3748253

Abstract Article PDF–1.1M

Select item 84525204.

Troy/Tnfrsf19 marks epidermal cells that govern interfollicular epidermal renewal and cornification

Kai Kretzschmar, Kim E. Boonekamp, Margit Bleijs, Priyanca Asra, Mandy Koomen, Susana M. Chuva de Sousa Lopes, Barbara Giovannone, Hans Clevers

Stem Cell Reports. 2021 Sep 14; 16(9): 2379–2394. Published online 2021 Aug 5. doi: 10.1016/j.stemcr.2021.07.007

PMCID:: PMC8452520

Abstract Article PDF–4.3M

Select item 67071105.

Immunohistochemical Analysis of LGR5 and TROY Expression in Gastric Carcinogenesis Demonstrates an Inverse Trend

Samaneh Saberi, Abbas Piryaei, Esmat Mirabzadeh, Maryam Esmaeili, Toktam Karimi, Sara Momtaz, Afshin Abdirad, Niloofar Sodeifi, Mohammad Ali Mohagheghi, Hossein Baharvand, Marjan Mohammadi

Iran Biomed J. 2019 Mar; 23(2): 107–120. doi: 10.29252/.23.2.107

PMCID:: PMC6707110

Abstract Article PDF–1.8M

Select item 61403796.

PDZ-RhoGEF Is a Signaling Effector for TROY-Induced Glioblastoma Cell Invasion and Survival

Zonghui Ding, Harshil Dhruv, Aneta Kwiatkowska-Piwowarczyk, Rosamaria Ruggieri, Jean Kloss, Marc Symons, Patrick Pirrotte, Jennifer M. Eschbacher, Nhan L. Tran, Joseph C. Loftus

Neoplasia. 2018 Oct; 20(10): 1045–1058. Published online 2018 Sep 13. doi: 10.1016/j.neo.2018.08.008

PMCID:: PMC6140379

Abstract Article PDF–999K

Select item 58056287.

Novel Signaling Complex Between TROY and EGFR Mediates Glioblastoma Cell Invasion

Zonghui Ding, Alison Roos, Jean Kloss, Harshil Dhruv, Sen Peng, Patrick Pirrotte, Jennifer M. Eschbacher, Nhan L. Tran, Joseph C. Loftus

Mol Cancer Res. Author manuscript; available in PMC 2019 Feb 1.

Published in final edited form as: Mol Cancer Res. 2018 Feb; 16(2): 322–332. Published online 2017 Nov 8. doi: 10.1158/1541-7786.MCR-17-0454

PMCID:: PMC5805628

Abstract Article PDF–1.0M

Select item 30925288.

TROY (TNFRSF19) is Overexpressed in Advanced Glial Tumors and Promotes Glioblastoma Cell Invasion via Pyk2-Rac1 Signaling

Vincent M. Paulino, Zhongbo Yang, Jean Kloss, Matthew J. Ennis, Brock A. Armstrong, Joseph C. Loftus, Nhan L. Tran

Mol Cancer Res. Author manuscript; available in PMC 2011 Nov 1.

Published in final edited form as: Mol Cancer Res. 2010 Nov; 8(11): 1558–1567. Published online 2010 Sep 29. doi: 10.1158/1541-7786.MCR-10-0334

PMCID:: PMC3092528

Abstract Article PDF–572K

Select item 67155229.

A Four-gene Transcript Score to Predict Metastatic-lethal Progression in Men Treated for Localized Prostate Cancer: Development and Validation Studies

Anqi Cheng, Shanshan Zhao, Liesel M. FitzGerald, Jonathan L. Wright, Suzanne Kolb, R. Jeffrey Karnes, Robert B. Jenkins, Elai Davicioni, Elaine A. Ostrander, Ziding Feng, Jian-Bing Fan, James Y. Dai, Janet L. Stanford

Prostate. Author manuscript; available in PMC 2020 Oct 1.

Published in final edited form as: Prostate. 2019 Oct; 79(14): 1589–1596. Published online 2019 Aug 2. doi: 10.1002/pros.23882

PMCID:: PMC6715522

Abstract Article PDF–558K

Select item 637247910.

TROY interacts with RKIP to promote glioma development

Xiujie Liu, Yinghui Bao, Wei Meng, Ping Yang, Yi An, Jie Ma, Yujie Tang, Zhigang Liu, Yan Lu, Jianfeng Zhou, Yong Zhang, Jifeng Feng, Xiaofei Gao, Zhida Su, Yingyan Pu, Cheng He

Oncogene. 2019; 38(9): 1544–1559. Published online 2018 Oct 18. doi: 10.1038/s41388-018-0503-x

PMCID:: PMC6372479

Abstract Article PDF–6.5M

Select item 383716811.

TROY Interacts with Rho Guanine Nucleotide Dissociation Inhibitor α (RhoGDIα) to Mediate Nogo-induced Inhibition of Neurite Outgrowth

Yan Lu, Xiujie Liu, Jianfeng Zhou, Aijun Huang, Jiazhen Zhou, Cheng He

J Biol Chem. 2013 Nov 22; 288(47): 34276–34286. Published online 2013 Oct 15. doi: 10.1074/jbc.M113.519744

PMCID:: PMC3837168

Abstract Article PDF–2.5M

Select item 12437312.

TRAF6-deficient mice display hypohidrotic ectodermal dysplasia

Asuka Naito, Hisahiro Yoshida, Eri Nishioka, Mizuho Satoh, Sakura Azuma, Tadashi Yamamoto, Shin-ichi Nishikawa, Jun-ichiro Inoue

Proc Natl Acad Sci U S A. 2002 Jun 25; 99(13): 8766–8771. Published online 2002 Jun 11. doi: 10.1073/pnas.132636999

PMCID:: PMC124373

Abstract Article PDF–834K

Select item 271383113.

Local Network Topology in Human Protein Interaction Data Predicts Functional Association

Hua Li, Shoudan Liang

PLoS One. 2009; 4(7): e6410. Published online 2009 Jul 29. doi: 10.1371/journal.pone.0006410

PMCID:: PMC2713831

Abstract Article PDF–800K

Select item 440234814.

Gene–Smoking Interactions Identify Several Novel Blood Pressure Loci in the Framingham Heart Study

Yun J. Sung, Lisa de las Fuentes, Karen L. Schwander, Jeannette Simino, Dabeeru C. Rao

Am J Hypertens. 2015 Mar; 28(3): 343–354. Published online 2014 Sep 3. doi: 10.1093/ajh/hpu149

PMCID:: PMC4402348

Abstract Article PDF–38M

Select item 332102315.

Novel Associations for Hypothyroidism Include Known Autoimmune Risk Loci

Nicholas Eriksson, Joyce Y. Tung, Amy K. Kiefer, David A. Hinds, Uta Francke, Joanna L. Mountain, Chuong B. Do

PLoS One. 2012; 7(4): e34442. Published online 2012 Apr 6. doi: 10.1371/journal.pone.0034442

PMCID:: PMC3321023

Abstract Article PDF–750K

Select item 981605916.

CST1 inhibits ferroptosis and promotes gastric cancer metastasis by regulating GPX4 protein stability via OTUB1

Dongbao Li, Yuhong Wang, Chao Dong, Tao Chen, Anqi Dong, Jiayu Ren, Weikang Li, Gege Shu, Jiaoyang Yang, Wenhao Shen, Lei Qin, Lin Hu, Jin Zhou

Oncogene. 2023; 42(2): 83–98. Published online 2022 Nov 12. doi: 10.1038/s41388-022-02537-x

PMCID:: PMC9816059

Abstract Article PDF–7.6M

Select item 464965817.

Dependence of Human Colorectal Cells Lacking the FBW7 Tumor Suppressor on the Spindle Assembly Checkpoint

Melanie L. Bailey, Tejomayee Singh, Patricia Mero, Jason Moffat, Philip Hieter

Genetics. 2015 Nov; 201(3): 885–895. Published online 2015 Sep 8. doi: 10.1534/genetics.115.180653

PMCID:: PMC4649658

Abstract Article PDF–1.8M

Select item 334973418.

Genome-Wide Association for Abdominal Subcutaneous and Visceral Adipose Reveals a Novel Locus for Visceral Fat in Women

Caroline S. Fox, Yongmei Liu, Charles C. White, Mary Feitosa, Albert V. Smith, Nancy Heard-Costa, Kurt Lohman, GIANT Consortium, MAGIC Consortium, GLGC Consortium, Andrew D. Johnson, Meredith C. Foster, Danielle M. Greenawalt, Paula Griffin, Jinghong Ding, Anne B. Newman, Fran Tylavsky, Iva Miljkovic, Stephen B. Kritchevsky, Lenore Launer, Melissa Garcia, Gudny Eiriksdottir, J. Jeffrey Carr, Vilmunder Gudnason, Tamara B. Harris, L. Adrienne Cupples, Ingrid B. Borecki

PLoS Genet. 2012 May; 8(5): e1002695. Published online 2012 May 10. doi: 10.1371/journal.pgen.1002695