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Select item 109052701.

PRIM2: A Marker of MYC-driven Hyper-proliferation, Disease Progression, Tumor Aggressiveness and Poor Survival in Glioma Patients

RONGHUI SUN, XIAODONG SHAO, FARHANA AKTER, KASHIF RAFIQ ZAHID, SHUN YAO, LIANTING MA, GUOZHENG XU

Cancer Genomics Proteomics. 2024 Mar-Apr; 21(2): 186–202. Published online 2024 Mar 3. doi: 10.21873/cgp.20440

PMCID:: PMC10905270

Abstract Article PDF–12M

Select item 62987312.

Functional and structural similarity of human DNA primase [4Fe4S] cluster domain constructs

Marilyn E. Holt, Lauren E. Salay, Elizabeth O’Brien, Jacqueline K. Barton, Walter J. Chazin

PLoS One. 2018; 13(12): e0209345. Published online 2018 Dec 18. doi: 10.1371/journal.pone.0209345

PMCID:: PMC6298731

Abstract Article PDF–1.1M

Select item 33688083.

Lack of genomic imprinting of DNA primase, polypeptide 2 (PRIM2) in human term placenta and white blood cells

Jaewook Chung, Shengdar Tsai, Andra H. James, Betty H. Thames, Stephanie Shytle, Jorge A. Piedrahita

Epigenetics. 2012 May 1; 7(5): 429–431. doi: 10.4161/epi.19777

PMCID:: PMC3368808

Abstract Article PDF–577K

Select item 31008744.

Crystal structure of the C-terminal domain of human DNA primase large subunit: Implications for the mechanism of the primase—polymerase α switch

Vinod B Agarkar, Nigar D Babayeva, Youri I Pavlov, Tahir H Tahirov

Cell Cycle. 2011 Mar 15; 10(6): 926–931. Published online 2011 Mar 15. doi: 10.4161/cc.10.6.15010

PMCID:: PMC3100874

Abstract Article PDF–2.3M

Select item 29975585.

The Genomic Distribution and Local Context of Coincident SNPs in Human and Chimpanzee

Alan Hodgkinson, Adam Eyre-Walker

Genome Biol Evol. 2010; 2: 547–557. Published online 2010 Jul 8. doi: 10.1093/gbe/evq039

PMCID:: PMC2997558

Abstract Article PDF–2.3M

Select item 26918166.

XRCC1 interacts with the p58 subunit of DNA Pol α-primase and may coordinate DNA repair and replication during S phase

Nicolas Lévy, Maren Oehlmann, François Delalande, Heinz Peter Nasheuer, Alain Van Dorsselaer, Valérie Schreiber, Gilbert de Murcia, Josiane Ménissier-de Murcia, Domenico Maiorano, Anne Bresson

Nucleic Acids Res. 2009 Jun; 37(10): 3177–3188. Published online 2009 Mar 21. doi: 10.1093/nar/gkp144

PMCID:: PMC2691816

Abstract Article PDF–2.8M

Select item 43424767.

Crystal Structure of the Human Primase

Andrey G. Baranovskiy, Yinbo Zhang, Yoshiaki Suwa, Nigar D. Babayeva, Jianyou Gu, Youri I. Pavlov, Tahir H. Tahirov

J Biol Chem. 2015 Feb 27; 290(9): 5635–5646. Published online 2014 Dec 30. doi: 10.1074/jbc.M114.624742

PMCID:: PMC4342476

Abstract Article PDF–5.1M

Select item 41392188.

The C-terminal Domain of the DNA Polymerase Catalytic Subunit Regulates the Primase and Polymerase Activities of the Human DNA Polymerase α-Primase Complex

Yinbo Zhang, Andrey G. Baranovskiy, Tahir H. Tahirov, Youri I. Pavlov

J Biol Chem. 2014 Aug 8; 289(32): 22021–22034. Published online 2014 Jun 24. doi: 10.1074/jbc.M114.570333

PMCID:: PMC4139218

Abstract Article PDF–3.2M

Select item 29222899.

Insights into eukaryotic DNA priming from the structure and functional interactions of the 4Fe-4S cluster domain of human DNA primase

Sivaraja Vaithiyalingam, Eric M. Warren, Brandt F. Eichman, Walter J. Chazin

Proc Natl Acad Sci U S A. 2010 Aug 3; 107(31): 13684–13689. Published online 2010 Jul 19. doi: 10.1073/pnas.1002009107

PMCID:: PMC2922289

Abstract Article PDF–1.2M

Select item 891670810.

Genetic variants of CHEK1, PRIM2 and CDK6 in the mitotic phase-related pathway are associated with non-small cell lung cancer survival

Rui Mu, Hongliang Liu, Sheng Luo, Edward F. Patz, Jr., Carolyn Glass, Li Su, Mulong Du, David C. Christiani, Lei Jin, Qingyi Wei

Int J Cancer. Author manuscript; available in PMC 2022 Mar 11.

Published in final edited form as: Int J Cancer. 2021 Sep 15; 149(6): 1302–1312. Published online 2021 Jun 10. doi: 10.1002/ijc.33702

PMCID:: PMC8916708

Abstract Article PDF–1.0M

Select item 481350011.

Insight into the Human DNA Primase Interaction with Template-Primer

Andrey G. Baranovskiy, Yinbo Zhang, Yoshiaki Suwa, Jianyou Gu, Nigar D. Babayeva, Youri I. Pavlov, Tahir H. Tahirov

J Biol Chem. 2016 Feb 26; 291(9): 4793–4802. Published online 2015 Dec 28. doi: 10.1074/jbc.M115.704064

PMCID:: PMC4813500

Abstract Article PDF–1.5M

Select item 485895512.

Mechanism of Concerted RNA-DNA Primer Synthesis by the Human Primosome

Andrey G. Baranovskiy, Nigar D. Babayeva, Yinbo Zhang, Jianyou Gu, Yoshiaki Suwa, Youri I. Pavlov, Tahir H. Tahirov

J Biol Chem. 2016 May 6; 291(19): 10006–10020. Published online 2016 Mar 14. doi: 10.1074/jbc.M116.717405

PMCID:: PMC4858955

Abstract Article PDF–8.1M

Select item 866171713.

Structural basis for the interaction of SARS‐CoV‐2 virulence factor nsp1 with DNA polymerase α–primase

Mairi L. Kilkenny, Charlotte E. Veale, Amir Guppy, Steven W. Hardwick, Dimitri Y. Chirgadze, Neil J. Rzechorzek, Joseph D. Maman, Luca Pellegrini

Protein Sci. 2022 Feb; 31(2): 333–344. Published online 2021 Nov 12. doi: 10.1002/pro.4220

PMCID:: PMC8661717

Abstract Article PDF–7.6M

Select item 866505414.

A 3D Structural SARS-CoV-2-Human Interactome to Explore Genetic and Drug Perturbations

Shayne D. Wierbowski, Siqi Liang, Yuan Liu, You Chen, Shagun Gupta, Nicole M. Andre, Steven M. Lipkin, Gary R. Whittaker, Haiyuan Yu

Nat Methods. Author manuscript; available in PMC 2022 May 29.

Published in final edited form as: Nat Methods. 2021 Dec; 18(12): 1477–1488. Published online 2021 Nov 29. doi: 10.1038/s41592-021-01318-w

PMCID:: PMC8665054

Abstract Article PDF–2.9M

Select item 559420515.

Smarcal1-Mediated Fork Reversal Triggers Mre11-Dependent Degradation of Nascent DNA in the Absence of Brca2 and Stable Rad51 Nucleofilaments

Arun Mouli Kolinjivadi, Vincenzo Sannino, Anna De Antoni, Karina Zadorozhny, Mairi Kilkenny, Hervé Técher, Giorgio Baldi, Rong Shen, Alberto Ciccia, Luca Pellegrini, Lumir Krejci, Vincenzo Costanzo

Mol Cell. 2017 Sep 7; 67(5): 867–881.e7. doi: 10.1016/j.molcel.2017.07.001

PMCID:: PMC5594205

Abstract Article

Select item 339064816.

A Conserved Motif in the C-terminal Tail of DNA Polymerase α Tethers Primase to the Eukaryotic Replisome

Mairi L. Kilkenny, Giacomo De Piccoli, Rajika L. Perera, Karim Labib, Luca Pellegrini

J Biol Chem. 2012 Jul 6; 287(28): 23740–23747. Published online 2012 May 16. doi: 10.1074/jbc.M112.368951

PMCID:: PMC3390648

Abstract Article PDF–1.5M

Select item 367560217.

IOP1 Protein Is an External Component of the Human Cytosolic Iron-Sulfur Cluster Assembly (CIA) Machinery and Functions in the MMS19 Protein-dependent CIA Pathway

Mineaki Seki, Yukiko Takeda, Kazuhiro Iwai, Kiyoji Tanaka

J Biol Chem. 2013 Jun 7; 288(23): 16680–16689. Published online 2013 Apr 12. doi: 10.1074/jbc.M112.416602

PMCID:: PMC3675602

Abstract Article PDF–1.3M

Select item 412386218.

Genome-Wide Association Study of Plasma N6 Polyunsaturated Fatty Acids within the CHARGE Consortium

Weihua Guan, Brian T. Steffen, Rozenn N. Lemaitre, Jason H.Y. Wu, Toshiko Tanaka, Ani Manichaikul, Millennia Foy, Stephen S. Rich, Lu Wang, Jennifer A. Nettleton, Weihong Tang, Xiangjun Gu, Stafania Bandinelli, Irena B. King, Barbara McKnight, Bruce M. Psaty, David Siscovick, Luc Djousse, Yii-Der Ida Chen, Luigi Ferrucci, Myriam Fornage, Dariush Mozafarrian, Michael Y. Tsai, Lyn M. Steffen

Circ Cardiovasc Genet. Author manuscript; available in PMC 2015 Jun 1.

Published in final edited form as: Circ Cardiovasc Genet. 2014 Jun; 7(3): 321–331. Published online 2014 May 13. doi: 10.1161/CIRCGENETICS.113.000208

PMCID:: PMC4123862

Abstract Article PDF–430K

Select item 378499019.

Human CIA2A (FAM96A) and CIA2B (FAM96B) integrate maturation of different subsets of cytosolic-nuclear iron-sulfur proteins and iron homeostasis

Oliver Stehling, Judita Mascarenhas, Ajay A. Vashisht, Alex D. Sheftel, Brigitte Niggemeyer, Ralf Rösser, Antonio J. Pierik, James A. Wohlschlegel, Roland Lill

Cell Metab. Author manuscript; available in PMC 2014 Aug 6.

Published in final edited form as: Cell Metab. 2013 Aug 6; 18(2): 187–198. Published online 2013 Jul 25. doi: 10.1016/j.cmet.2013.06.015

Correction in:: Cell Metab. 2018 Jan 9; 27(1): 263.

PMCID:: PMC3784990

Abstract Article PDF–3.8M

Select item 573529720.

Identification of translationally controlled tumor protein in promotion of DNA homologous recombination repair in cancer cells by affinity proteomics

Y Li, H Sun, C Zhang, J Liu, H Zhang, F Fan, R A Everley, X Ning, Y Sun, J Hu, J Liu, J Zhang, W Ye, X Qiu, S Dai, B Liu, H Xu, S Fu, S P Gygi, C Zhou

Oncogene. 2017 Dec 14; 36(50): 6839–6849. Published online 2017 Aug 28. doi: 10.1038/onc.2017.289

PMCID:: PMC5735297

Abstract Article PDF–1.3M

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