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Items: 1 to 20 of 150

1.
OTUB1 contributes to the stability and function of Influenza A virus NS2
Yu-Jyun Li, Chi-Yuan Chen, Yu-Shen Kuo, Yi-Wen Huang, Rei-Lin Kuo, Li-Kwan Chang, Jeng-How Yang, Chih-Ho Lai, Shin-Ru Shih, Ya-Fang Chiu
PLoS Pathog. 2024 May; 20(5): e1012279. Published online 2024 May 30. doi: 10.1371/journal.ppat.1012279
PMCID:
PMC11166342
AbstractArticlePDF–2.7M
2.
Amyloid aggregates of the deubiquitinase OTUB1 are neurotoxic, suggesting that they contribute to the development of Parkinson's disease
Raniki Kumari, Roshan Kumar, Sanjay Kumar, Abhishek Kumar Singh, Pranita Hanpude, Deepak Jangir, Tushar Kanti Maiti
J Biol Chem. 2020 Mar 13; 295(11): 3466–3484. Published online 2020 Jan 31. doi: 10.1074/jbc.RA119.009546
PMCID:
PMC7076217
AbstractArticlePDF–7.1M
3.
The non‐coding RNA OTUB1‐isoform2 promotes ovarian tumour progression and predicts poor prognosis
Shunni Wang, Yan Ning, Ping Wei, Dongliag Cai, Linghui Lu, Jing Li, Yiqin Wang
J Cell Mol Med. 2018 Oct; 22(10): 4794–4806. Published online 2018 Jul 25. doi: 10.1111/jcmm.13733
PMCID:
PMC6156285
AbstractArticlePDF–1.3M
4.
OTUB1 triggers lung cancer development by inhibiting RAS monoubiquitination
Maria Francesca Baietti, Michal Simicek, Layka Abbasi Asbagh, Enrico Radaelli, Sam Lievens, Jonathan Crowther, Mikhail Steklov, Vasily N Aushev, David Martínez García, Jan Tavernier, Anna A Sablina
EMBO Mol Med. 2016 Mar; 8(3): 288–303. Published online 2016 Feb 8. doi: 10.15252/emmm.201505972
PMCID:
PMC4772950
AbstractArticlePDF–1.4M
5.
OTUB1 promotes metastasis and serves as a marker of poor prognosis in colorectal cancer
Yi Zhou, Jiangxue Wu, Xiang Fu, Wuying Du, Ling Zhou, Xiangqi Meng, Hongyan Yu, Jiaxin Lin, Wen Ye, Jiani Liu, Hui Peng, Ran-yi Liu, Changchuan Pan, Wenlin Huang
Mol Cancer. 2014; 13: 258. Published online 2014 Nov 28. doi: 10.1186/1476-4598-13-258
PMCID:
PMC4351937
AbstractArticlePDF–1.8M
6.
OTUB1 accelerates hepatocellular carcinoma by stabilizing RACK1 via its non-canonical ubiquitination
Liqun Peng, Tiangen Wu, Yingyi Liu, Dongli Zhao, Wenzhi He, Yufeng Yuan
Cell Oncol (Dordr) 2024; 47(3): 987–1004. Published online 2024 Feb 5. doi: 10.1007/s13402-023-00913-7
PMCID:
PMC11219430
AbstractArticlePDF–8.4M
7.
Involvement of the OTUB1‐YAP1 axis in driving malignant behaviors of head and neck squamous cell carcinoma
Shengjian Jin, Takaaki Tsunematsu, Taigo Horiguchi, Yasuhiro Mouri, Wenhua Shao, Keiko Miyoshi, Hiroko Hagita, Motoharu Sarubo, Natsumi Fujiwara, Guangying Qi, Naozumi Ishimaru, Yasusei Kudo
Cancer Med. 2023 Dec; 12(24): 22156–22169. Published online 2023 Nov 20. doi: 10.1002/cam4.6735
PMCID:
PMC10757095
AbstractArticlePDF–3.3M
8.
OTUB1 inhibits breast cancer by non‐canonically stabilizing CCN6
Ying Zhao, Jing Ruan, Zhongding Li, Xian Su, Kangmin Chen, Yimin Lin, Yuepiao Cai, Peng Wang, Baohua Liu, Dirk Schlüter, Guang Liang, Xu Wang
Clin Transl Med. 2023 Aug; 13(8): e1385. Published online 2023 Aug 22. doi: 10.1002/ctm2.1385
PMCID:
PMC10444971
AbstractArticlePDF–6.0M
9.
Deubiquitination of MYC by OTUB1 contributes to HK2 mediated glycolysis and breast tumorigenesis
Xue Han, Chune Ren, Chao Lu, Pengyun Qiao, Tingting Yang, Zhenhai Yu
Cell Death Differ. 2022 Sep; 29(9): 1864–1873. Published online 2022 Mar 16. doi: 10.1038/s41418-022-00971-8
PMCID:
PMC9433372
AbstractArticlePDF–7.3M
10.
OTUB1 augments hypoxia signaling via its non-canonical ubiquitination inhibition of HIF-1α during hypoxia adaptation
Xing Liu, Hongyan Deng, Jinhua Tang, Zixuan Wang, Chunchun Zhu, Xiaolian Cai, Fangjing Rong, Xiaoyun Chen, Xueyi Sun, Shuke Jia, Gang Ouyang, Wenhua Li, Wuhan Xiao
Cell Death Dis. 2022 Jun; 13(6): 560. Published online 2022 Jun 22. doi: 10.1038/s41419-022-05008-z
PMCID:
PMC9217984
AbstractArticlePDF–4.7M
11.
Overexpression of OTU domain-containing ubiquitin aldehyde-binding protein 1 exacerbates colorectal cancer malignancy by inhibiting protein degradation of β-Catenin via Ubiquitin-proteasome pathway
Daoxiong Ye, Sisi Wang, Xiaojie Wang, Yu Lin, Ying Huang, Pan Chi
Bioengineered. 2022; 13(4): 9106–9116. Published online 2022 Mar 30. doi: 10.1080/21655979.2022.2057897
PMCID:
PMC9161894
AbstractArticlePDF–3.2M
12.
Solasonine Inhibits Pancreatic Cancer Progression With Involvement of Ferroptosis Induction
Xiaoqiang Liang, Cheng Hu, Mian Han, Congying Liu, Xun Sun, Kui Yu, Honggang Gu, Jingzhe Zhang
Front Oncol. 2022; 12: 834729. Published online 2022 Apr 12. doi: 10.3389/fonc.2022.834729
PMCID:
PMC9039314
AbstractArticlePDF–18M
13.
The ubiquitin hydrolase OTUB1 promotes glioma cell stemness via suppressing ferroptosis through stabilizing SLC7A11 protein
Xinde Zhao, Ming Zhou, Yong Yang, Minjie Luo
Bioengineered. 2021; 12(2): 12636–12645. Published online 2021 Dec 19. doi: 10.1080/21655979.2021.2011633
PMCID:
PMC8810032
AbstractArticlePDF–2.6M
14.
OTUB1 knockdown promotes apoptosis in melanoma cells by upregulating TRAIL expression
Bok-Soon Lee, Sung Un Kang, Mei Huang, Yeon Soo Kim, Young-Sun Lee, Jae-Yong Park, Chul-Ho Kim
BMB Rep. 2021 Dec 31; 54(12): 608–613. Published online 2021 Dec 31. doi: 10.5483/BMBRep.2021.54.12.033
PMCID:
PMC8728537
AbstractArticlePDF–1.4M
15.
The deubiquitinase OTUB1 fosters papillary thyroid carcinoma growth through EYA1 stabilization
Peiyi Xie, Qing Chao, Jiuang Mao, Yue Liu, Jiayu Fang, Jing Xie, Jing Zhen, Yongqi Ding, Bidong Fu, Yun Ke, Da Huang
J Cell Mol Med. 2021 Dec; 25(23): 10980–10989. Published online 2021 Nov 12. doi: 10.1111/jcmm.17020
PMCID:
PMC8642681
AbstractArticlePDF–1.5M
16.
Deubiquitinating enzyme OTUB1 promotes cancer cell immunosuppression via preventing ER-associated degradation of immune checkpoint protein PD-L1
Dan Zhu, Ruidan Xu, Xinping Huang, Zefang Tang, Yonglu Tian, Jinfang Zhang, Xiaofeng Zheng
Cell Death Differ. 2021 Jun; 28(6): 1773–1789. Published online 2020 Dec 16. doi: 10.1038/s41418-020-00700-z
PMCID:
PMC8184985
AbstractArticlePDF–5.9M
17.
OTUB1 facilitates bladder cancer progression by stabilizing ATF6 in response to endoplasmic reticulum stress
Hui‐Hui Zhang, Chao Li, Jian‐Wei Ren, Lian Liu, Xue‐Hua Du, Jie Gao, Tao Liu, Shang‐Ze Li
Cancer Sci. 2021 Jun; 112(6): 2199–2209. Published online 2021 May 2. doi: 10.1111/cas.14876
PMCID:
PMC8177800
AbstractArticlePDF–1.9M
18.
OTUB1 stabilizes mismatch repair protein MSH2 by blocking ubiquitination
Qiong Wu, Yaping Huang, Liya Gu, Zhijie Chang, Guo-Min Li
J Biol Chem. 2021 Jan-Jun; 296: 100466. Published online 2021 Feb 26. doi: 10.1016/j.jbc.2021.100466
PMCID:
PMC8042173
AbstractArticlePDF–2.0M
19.
Inhibition of the Otub1/c-Maf axis by the herbal acevaltrate induces myeloma cell apoptosis
Tong Sun, Yujia Xu, Zhuan Xu, Biyin Cao, Zubin Zhang, Qi Wang, Yan Kong, Xinliang Mao
Cell Commun Signal. 2021; 19: 24. Published online 2021 Feb 24. doi: 10.1186/s12964-020-00676-w
PMCID:
PMC7905600
AbstractArticlePDF–3.5M
20.
OTUB1 Promotes Progression and Proliferation of Prostate Cancer via Deubiquitinating and Stabling Cyclin E1
Yihao Liao, Ning Wu, Keke Wang, Miaomiao Wang, Youzhi Wang, Jie Gao, Boqiang Zhong, Fuling Ma, Yudong Wu, Ning Jiang
Front Cell Dev Biol. 2020; 8: 617758. Published online 2021 Jan 18. doi: 10.3389/fcell.2020.617758
PMCID:
PMC7848094
AbstractArticlePDF–4.6M

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