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Items: 1 to 20 of 43

1.
AMPKβ1 and AMPKβ2 define an isoform-specific gene signature in human pluripotent stem cells, differentially mediating cardiac lineage specification
Nicole Ziegler, Erik Bader, Alexey Epanchintsev, Daniel Margerie, Aimo Kannt, Dieter Schmoll
J Biol Chem. 2020 Dec 18; 295(51): 17659–17671. Published online 2020 Oct 16. doi: 10.1074/jbc.RA120.013990
PMCID:
PMC7762962
AbstractArticlePDF–3.1M
2.
Sumoylation of AMPKβ2 subunit enhances AMP-activated protein kinase activity
Teresa Rubio, Santiago Vernia, Pascual Sanz
Mol Biol Cell. 2013 Jun 1; 24(11): 1801–1811. doi: 10.1091/mbc.E12-11-0806
PMCID:
PMC3667731
AbstractArticlePDF–2.7M
3.
AMP-activated protein kinase complexes containing the β2 regulatory subunit are up-regulated during and contribute to adipogenesis
Omar J. Katwan, Fatmah Alghamdi, Tarek A. Almabrouk, Sarah J. Mancini, Simon Kennedy, Jonathan S. Oakhill, John W. Scott, Ian P. Salt
Biochem J. 2019 Jun 28; 476(12): 1725–1740. Prepublished online 2019 Jun 12. Published online 2019 Jun 26. doi: 10.1042/BCJ20180714
PMCID:
PMC6595317
AbstractArticlePDF–4.4M
4.
Conformational heterogeneity of the allosteric drug and metabolite (ADaM) site in AMP-activated protein kinase (AMPK)
Xin Gu, Michael D. Bridges, Yan Yan, Parker W. de Waal, X. Edward Zhou, Kelly M. Suino-Powell, H. Eric Xu, Wayne L. Hubbell, Karsten Melcher
J Biol Chem. 2018 Nov 2; 293(44): 16994–17007. Published online 2018 Sep 11. doi: 10.1074/jbc.RA118.004101
PMCID:
PMC6222100
AbstractArticlePDF–1.7M
5.
AMP-activated Protein Kinase Regulation and Biological Actions in the Heart
Lawrence H. Young, Vlad G. Zaha
Circ Res. Author manuscript; available in PMC 2015 Apr 14.
Published in final edited form as: Circ Res. 2012 Aug 31; 111(6): 800–814. doi: 10.1161/CIRCRESAHA.111.255505
PMCID:
PMC4397099
AbstractArticlePDF–785K
6.
Structure of Mammalian AMPK and its regulation by ADP
Bing Xiao, Matthew J. Sanders, Elizabeth Underwood, Richard Heath, Faith Mayer, David Carmena, Chun Jing, Philip A. Walker, John F. Eccleston, Lesley F. Haire, Peter Saiu, Steven A. Howell, Rein Aasland, Stephen R. Martin, David Carling, Steven J. Gamblin
Nature. Author manuscript; available in PMC 2011 Oct 1.
Published in final edited form as: Nature. 2011 Apr 14; 472(7342): 230–233. Published online 2011 Mar 13. doi: 10.1038/nature09932
PMCID:
PMC3078618
AbstractArticlePDF–1.4M
7.
The Laforin–Malin Complex, Involved in Lafora Disease, Promotes the Incorporation of K63-linked Ubiquitin Chains into AMP-activated Protein Kinase β Subunits
Daniel Moreno, Mhairi C. Towler, D. Grahame Hardie, Erwin Knecht, Pascual Sanz
Mol Biol Cell. 2010 Aug 1; 21(15): 2578–2588. doi: 10.1091/mbc.E10-03-0227
PMCID:
PMC2912345
AbstractArticlePDF–2.6M
8.
Structural basis of AMPK regulation by adenine nucleotides and glycogen
Xiaodan Li, Lili Wang, X Edward Zhou, Jiyuan Ke, Parker W de Waal, Xin Gu, M H Eileen Tan, Dongye Wang, Donghai Wu, H Eric Xu, Karsten Melcher
Cell Res. 2015 Jan; 25(1): 50–66. Published online 2014 Nov 21. doi: 10.1038/cr.2014.150
Correction in:
Cell Res. 2015 Mar; 25(3): 398.
PMCID:
PMC4650587
AbstractArticlePDF–2.5M
9.
Sestrin2 Modulates AMPK Subunit Expression and Its Response to Ionizing Radiation in Breast Cancer Cells
Toran Sanli, Katja Linher-Melville, Theodoros Tsakiridis, Gurmit Singh
PLoS One. 2012; 7(2): e32035. Published online 2012 Feb 20. doi: 10.1371/journal.pone.0032035
PMCID:
PMC3282792
AbstractArticlePDF–507K
10.
Over-expressions of AMPK subunits in ovarian carcinomas with significant clinical implications
Cuilan Li, Vincent WS Liu, Pui M Chiu, David W Chan, Hextan YS Ngan
BMC Cancer. 2012; 12: 357. Published online 2012 Aug 16. doi: 10.1186/1471-2407-12-357
PMCID:
PMC3518102
AbstractArticlePDF–2.5M
11.
Lack of Adipocyte AMPK Exacerbates Insulin Resistance and Hepatic Steatosis through Brown and Beige Adipose Tissue Function
Emilio P. Mottillo, Eric M. Desjardins, Justin D. Crane, Brennan K. Smith, Alex E. Green, Serge Ducommun, Tora I. Henriksen, Irena A. Rebalka, Aida Razi, Kei Sakamoto, Camilla Scheele, Bruce E. Kemp, Thomas J. Hawke, Joaquin Ortega, James G. Granneman, Gregory R. Steinberg
Cell Metab. Author manuscript; available in PMC 2017 Jan 16.
Published in final edited form as: Cell Metab. 2016 Jul 12; 24(1): 118–129. doi: 10.1016/j.cmet.2016.06.006
PMCID:
PMC5239668
AbstractArticlePDF–1.8M
12.
AMP-activated Protein Kinase Phosphorylates R5/PTG, the Glycogen Targeting Subunit of the R5/PTG-Protein Phosphatase 1 Holoenzyme, and Accelerates Its Down-regulation by the Laforin-Malin Complex
Santiago Vernia, M. Carmen Solaz-Fuster, José Vicente Gimeno-Alcañiz, Teresa Rubio, Luisa García-Haro, Marc Foretz, Santiago Rodríguez de Córdoba, Pascual Sanz
J Biol Chem. 2009 Mar 27; 284(13): 8247–8255. doi: 10.1074/jbc.M808492200
PMCID:
PMC2659182
AbstractArticlePDF–614K
13.
Characterization of AMP-activated protein kinase gamma-subunit isoforms and their role in AMP binding.
P C Cheung, I P Salt, S P Davies, D G Hardie, D Carling
Biochem J. 2000 Mar 15; 346(Pt 3): 659–669.
PMCID:
PMC1220898
SummaryPDF–442K
14.
Protein Kinase A Phosphorylation Activates Vpr-Induced Cell Cycle Arrest during Human Immunodeficiency Virus Type 1 Infection
R. Anthony Barnitz, Fengyi Wan, Vinay Tripuraneni, Diane L. Bolton, Michael J. Lenardo
J Virol. 2010 Jul; 84(13): 6410–6424. Published online 2010 Apr 14. doi: 10.1128/JVI.02273-09
PMCID:
PMC2903295
AbstractArticlePDF–3.3M
15.
AMPK signaling linked to the schizophrenia-associated 1q21.1 deletion is required for neuronal and sleep maintenance
Stanislav Nagy, Gianna W. Maurer, Julie L. Hentze, Morten Rose, Thomas M. Werge, Kim Rewitz
PLoS Genet. 2018 Dec; 14(12): e1007623. Published online 2018 Dec 19. doi: 10.1371/journal.pgen.1007623
PMCID:
PMC6317821
AbstractArticlePDF–3.0M
16.
Common Variants in 40 Genes Assessed for Diabetes Incidence and Response to Metformin and Lifestyle Intervention in the Diabetes Prevention Program
Kathleen A. Jablonski, Jarred B. McAteer, Paul I.W. de Bakker, Paul W. Franks, Toni I. Pollin, Robert L. Hanson, Richa Saxena, Sarah Fowler, Alan R. Shuldiner, William C. Knowler, David Altshuler, Jose C. Florez, for the Diabetes Prevention Program Research Group
Diabetes. 2010 Oct; 59(10): 2672–2681. Published online 2010 Aug 3. doi: 10.2337/db10-0543
PMCID:
PMC3279522
AbstractArticlePDF–108K
17.
Insight into hepatocellular carcinogenesis at transcriptome level by comparing gene expression profiles of hepatocellular carcinoma with those of corresponding noncancerous liver
Xiang-Ru Xu, Jian Huang, Zhi-Gang Xu, Bin-Zhi Qian, Zhi-Dong Zhu, Qing Yan, Ting Cai, Xin Zhang, Hua-Sheng Xiao, Jian Qu, Feng Liu, Qiu-Hua Huang, Zhi-Hong Cheng, Neng-Gan Li, Jian-Jun Du, Wei Hu, Kun-Tang Shen, Gang Lu, Gang Fu, Ming Zhong, Shu-Hua Xu, Wen-Yi Gu, Wei Huang, Xin-Tai Zhao, Geng-Xi Hu, Jian-Ren Gu, Zhu Chen, Ze-Guang Han
Proc Natl Acad Sci U S A. 2001 Dec 18; 98(26): 15089–15094. doi: 10.1073/pnas.241522398
PMCID:
PMC64988
AbstractArticlePDF–341K
18.
AMPK Interactome Reveals New Function in Non-homologous End Joining DNA Repair
Zhen Chen, Chao Wang, Antrix Jain, Mrinal Srivastava, Mengfan Tang, Huimin Zhang, Xu Feng, Litong Nie, Dan Su, Yun Xiong, Sung Yun Jung, Jun Qin, Junjie Chen
Mol Cell Proteomics. 2020 Mar; 19(3): 467–477. Published online 2020 Jan 3. doi: 10.1074/mcp.RA119.001794
PMCID:
PMC7050103
AbstractArticlePDF–1.8M
19.
An Integrative Predictive Model of Coronary Artery Calcification in Arteriosclerosis
Michael McGeachie, Rachel L Badovinac Ramoni, Josyf C. Mychaleckyj, Karen L Furie, Jonathan M. Dreyfuss, Yongmei Liu, David Herrington, Xiuqing Guo, João A. Lima, Wendy Post, Jerome I. Rotter, Stephen Rich, Michèle Sale, Marco F. Ramoni
Circulation. Author manuscript; available in PMC 2010 Dec 15.
Published in final edited form as: Circulation. 2009 Dec 15; 120(24): 2448–2454. doi: 10.1161/CIRCULATIONAHA.109.865501
PMCID:
PMC2810344
AbstractArticlePDF–448K
20.
Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism
Roser Corominas, Xinping Yang, Guan Ning Lin, Shuli Kang, Yun Shen, Lila Ghamsari, Martin Broly, Maria Rodriguez, Stanley Tam, Shelly A. Wanamaker, Changyu Fan, Song Yi, Murat Tasan, Irma Lemmens, Xingyan Kuang, Nan Zhao, Dheeraj Malhotra, Jacob J. Michaelson, Vladimir Vacic, Michael A. Calderwood, Frederick P. Roth, Jan Tavernier, Steve Horvath, Kourosh Salehi-Ashtiani, Dmitry Korkin, Jonathan Sebat, David E. Hill, Tong Hao, Marc Vidal, Lilia M. Iakoucheva
Nat Commun. 2014; 5: 3650. Published online 2014 Apr 11. doi: 10.1038/ncomms4650
Correction in:
Nat Commun. 2023; 14: 569.
PMCID:
PMC3996537
AbstractArticlePDF–1.9M

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