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Select item 107835711.

TTC17 is an endoplasmic reticulum resident TPR-containing adaptor protein

Nathan P. Canniff, Jill B. Graham, Kevin P. Guay, Daniel A. Lubicki, Stephen J. Eyles, Jennifer N. Rauch, Daniel N. Hebert

J Biol Chem. 2023 Dec; 299(12): 105450. Published online 2023 Nov 8. doi: 10.1016/j.jbc.2023.105450

PMCID:: PMC10783571

Abstract Article PDF–2.7M

Select item 68296512.

New factors for protein transport identified by a genome-wide CRISPRi screen in mammalian cells

Laia Bassaganyas, Stephanie J. Popa, Max Horlbeck, Claudia Puri, Sarah E. Stewart, Felix Campelo, Anupama Ashok, Cristian M. Butnaru, Nathalie Brouwers, Kartoosh Heydari, Jean Ripoche, Jonathan Weissman, David C. Rubinsztein, Randy Schekman, Vivek Malhotra, Kevin Moreau, Julien Villeneuve

J Cell Biol. 2019 Nov 4; 218(11): 3861–3879. Published online 2019 Sep 5. doi: 10.1083/jcb.201902028

PMCID:: PMC6829651

Abstract Article PDF–5.6M

Select item 39035413.

C2orf62 and TTC17 Are Involved in Actin Organization and Ciliogenesis in Zebrafish and Human

Franck Bontems, Richard J. Fish, Irene Borlat, Frédérique Lembo, Sophie Chocu, Frédéric Chalmel, Jean-Paul Borg, Charles Pineau, Marguerite Neerman-Arbez, Amos Bairoch, Lydie Lane

PLoS One. 2014; 9(1): e86476. Published online 2014 Jan 27. doi: 10.1371/journal.pone.0086476

PMCID:: PMC3903541

Abstract Article PDF–13M

Select item 44477864.

A novel common variant in DCST2 is associated with length in early life and height in adulthood

Ralf J.P. van der Valk, Eskil Kreiner-Møller, Marjolein N. Kooijman, Mònica Guxens, Evangelia Stergiakouli, Annika Sääf, Jonathan P. Bradfield, Frank Geller, M. Geoffrey Hayes, Diana L. Cousminer, Antje Körner, Elisabeth Thiering, John A. Curtin, Ronny Myhre, Ville Huikari, Raimo Joro, Marjan Kerkhof, Nicole M. Warrington, Niina Pitkänen, Ioanna Ntalla, Momoko Horikoshi, Riitta Veijola, Rachel M. Freathy, Yik-Ying Teo, Sheila J. Barton, David M. Evans, John P. Kemp, Beate St Pourcain, Susan M. Ring, George Davey Smith, Anna Bergström, Inger Kull, Hakon Hakonarson, Frank D. Mentch, Hans Bisgaard, Bo Chawes, Jakob Stokholm, Johannes Waage, Patrick Eriksen, Astrid Sevelsted, Mads Melbye, Early Genetics and Lifecourse Epidemiology (EAGLE) Consortium, Cornelia M. van Duijn, Carolina Medina-Gomez, Albert Hofman, Johan C. de Jongste, H. Rob Taal, André G. Uitterlinden, Genetic Investigation of ANthropometric Traits (GIANT) Consortium, Loren L. Armstrong, Johan Eriksson, Aarno Palotie, Mariona Bustamante, Xavier Estivill, Juan R. Gonzalez, Sabrina Llop, Wieland Kiess, Anubha Mahajan, Claudia Flexeder, Carla M.T. Tiesler, Clare S. Murray, Angela Simpson, Per Magnus, Verena Sengpiel, Anna-Liisa Hartikainen, Sirkka Keinanen-Kiukaanniemi, Alexandra Lewin, Alexessander Da Silva Couto Alves, Alexandra I. Blakemore, Jessica L. Buxton, Marika Kaakinen, Alina Rodriguez, Sylvain Sebert, Marja Vaarasmaki, Timo Lakka, Virpi Lindi, Ulrike Gehring, Dirkje S. Postma, Wei Ang, John P. Newnham, Leo-Pekka Lyytikäinen, Katja Pahkala, Olli T. Raitakari, Kalliope Panoutsopoulou, Eleftheria Zeggini, Dorret I. Boomsma, Maria Groen-Blokhuis, Jorma Ilonen, Lude Franke, Joel N. Hirschhorn, Tune H. Pers, Liming Liang, Jinyan Huang, Berthold Hocher, Mikael Knip, Seang-Mei Saw, John W. Holloway, Erik Melén, Struan F.A. Grant, Bjarke Feenstra, William L. Lowe, Elisabeth Widén, Elena Sergeyev, Harald Grallert, Adnan Custovic, Bo Jacobsson, Marjo-Riitta Jarvelin, Mustafa Atalay, Gerard H. Koppelman, Craig E. Pennell, Harri Niinikoski, George V. Dedoussis, Mark I. Mccarthy, Timothy M. Frayling, Jordi Sunyer, Nicholas J. Timpson, Fernando Rivadeneira, Klaus Bønnelykke, Vincent W.V. Jaddoe

Hum Mol Genet. 2015 Feb 15; 24(4): 1155–1168. Published online 2014 Oct 3. doi: 10.1093/hmg/ddu510

PMCID:: PMC4447786

Abstract Article PDF–539K

Select item 49287165.

HIV–host interactome revealed directly from infected cells

Yang Luo, Erica Y. Jacobs, Todd M. Greco, Kevin D. Mohammed, Tommy Tong, Sarah Keegan, James M. Binley, Ileana M. Cristea, David Fenyö, Michael P. Rout, Brian T. Chait, Mark A. Muesing

Nat Microbiol. Author manuscript; available in PMC 2016 Jul 1.

Published in final edited form as: Nat Microbiol. 2016 Jul; 1(7): 16068. Published online 2016 May 23. doi: 10.1038/nmicrobiol.2016.68

PMCID:: PMC4928716

Abstract Article PDF–1.1M

Select item 79629946.

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy

Yanke Chen, Ting Jiang, Hongyi Zhang, Xingchun Gou, Cong Han, Jianhui Wang, Ann T. Chen, Jun Ma, Jun Liu, Zeming Chen, Xintao Jing, Hong Lei, Zhenzhen Wang, Youmei Bao, Mehdi Baqri, Yong Zhu, Ranjit S. Bindra, James E. Hansen, Jun Dou, Chen Huang, Jiangbing Zhou

Nat Cell Biol. Author manuscript; available in PMC 2021 Apr 1.

Published in final edited form as: Nat Cell Biol. 2020 Oct; 22(10): 1276–1285. Published online 2020 Oct 1. doi: 10.1038/s41556-020-00586-6

PMCID:: PMC7962994

Abstract Article PDF–5.5M

Select item 73730487.

Virus-Host Interactome and Proteomic Survey Reveal Potential Virulence Factors Influencing SARS-CoV-2 Pathogenesis

Jingjiao Li, Mingquan Guo, Xiaoxu Tian, Xin Wang, Xing Yang, Ping Wu, Chengrong Liu, Zixuan Xiao, Yafei Qu, Yue Yin, Chunxia Wang, Yucai Zhang, Zhaoqin Zhu, Zhenshan Liu, Chao Peng, Tongyu Zhu, Qiming Liang

Med (N Y) 2021 Jan 15; 2(1): 99–112.e7. Published online 2020 Jul 21. doi: 10.1016/j.medj.2020.07.002

PMCID:: PMC7373048

Abstract Article PDF–3.8M

Select item 72268128.

Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex

Marissa M. Minor, F. Blaine Hollinger, Adrienne L. McNees, Sung Yun Jung, Antrix Jain, Joseph M. Hyser, Karl-Dimiter Bissig, Betty L. Slagle

Cells. 2020 Apr; 9(4): 834. Published online 2020 Mar 30. doi: 10.3390/cells9040834

PMCID:: PMC7226812

Abstract Article PDF–2.3M

Select item 83145479.

SNX27-driven membrane localisation of OTULIN antagonises linear ubiquitination and NF-κB signalling activation

Ruona Shi, Xue Shi, Dajiang Qin, Shibing Tang, Michiel Vermeulen, Xiaofei Zhang

Cell Biosci. 2021; 11: 146. Published online 2021 Jul 27. doi: 10.1186/s13578-021-00659-5

PMCID:: PMC8314547

Abstract Article PDF–3.7M

Select item 650395210.

Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing

Tiina Viita, Salla Kyheröinen, Bina Prajapati, Jori Virtanen, Mikko J. Frilander, Markku Varjosalo, Maria K. Vartiainen

J Cell Sci. 2019 Apr 15; 132(8): jcs226852. Published online 2019 Apr 17. doi: 10.1242/jcs.226852

PMCID:: PMC6503952

Abstract Article

Select item 637572911.

Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains

Jean-Philippe Lambert, Sarah Picaud, Takao Fujisawa, Huayun Hou, Pavel Savitsky, Liis Uusküla-Reimand, Gagan D. Gupta, Hala Abdouni, Zhen-Yuan Lin, Monika Tucholska, James D.R. Knight, Beatriz Gonzalez-Badillo, Nicole St-Denis, Joseph A. Newman, Manuel Stucki, Laurence Pelletier, Nuno Bandeira, Michael D. Wilson, Panagis Filippakopoulos, Anne-Claude Gingras

Mol Cell. 2019 Feb 7; 73(3): 621–638.e17. doi: 10.1016/j.molcel.2018.11.006

PMCID:: PMC6375729

Abstract Article PDF–10M

Select item 895155612.

A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins

Danielle G. May, Laura Martin-Sancho, Valesca Anschau, Sophie Liu, Rachel J. Chrisopulos, Kelsey L. Scott, Charles T. Halfmann, Ramon Díaz Peña, Dexter Pratt, Alexandre R. Campos, Kyle J. Roux

Viruses. 2022 Mar; 14(3): 611. Published online 2022 Mar 15. doi: 10.3390/v14030611

PMCID:: PMC8951556

Abstract Article PDF–4.4M

Select item 852757813.

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity

Yuehui Zhang, Limin Shang, Jing Zhang, Yuchen Liu, Chaozhi Jin, Yanan Zhao, Xiaobo Lei, Wenjing Wang, Xia Xiao, Xiuyuan Zhang, Yujiao Liu, Linlin Liu, Meng-Wei Zhuang, Qingkun Mi, Chunyan Tian, Jianwei Wang, Fuchu He, Pei-Hui Wang, Jian Wang

Cell Chem Biol. 2022 Jan 20; 29(1): 5–18.e6. Published online 2021 Oct 20. doi: 10.1016/j.chembiol.2021.10.008

PMCID:: PMC8527578

Abstract Article PDF–4.5M

Select item 553358514.

The human cytoplasmic dynein interactome reveals novel activators of motility

William B Redwine, Morgan E DeSantis, Ian Hollyer, Zaw Min Htet, Phuoc Tien Tran, Selene K Swanson, Laurence Florens, Michael P Washburn, Samara L Reck-Peterson

eLife. 2017; 6: e28257. Published online 2017 Jul 18. doi: 10.7554/eLife.28257

PMCID:: PMC5533585

Abstract Article PDF–5.9M

Select item 554841315.

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling

Parveen Kumar, Prathyusha Munnangi, KVS Rammohan Chowdary, Varun J. Shah, Swapnil R. Shinde, Nanci R. Kolli, Rachita R. Halehalli, Hampapathalu A. Nagarajaram, Subbareddy Maddika

J Proteome Res. 2017 Aug 4; 16(8): 2789–2801. Published online 2017 Jul 4. doi: 10.1021/acs.jproteome.7b00065

PMCID:: PMC5548413

Abstract Article PDF–5.2M

Select item 851385316.

The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation

Jordan M. Meyers, Muthukumar Ramanathan, Ronald L. Shanderson, Aimee Beck, Laura Donohue, Ian Ferguson, Margaret G. Guo, Deepti S. Rao, Weili Miao, David Reynolds, Xue Yang, Yang Zhao, Yen-Yu Yang, Catherine Blish, Yinsheng Wang, Paul A. Khavari

PLoS Pathog. 2021 Oct; 17(10): e1009412. Published online 2021 Oct 1. doi: 10.1371/journal.ppat.1009412

PMCID:: PMC8513853

Abstract Article PDF–4.1M

Select item 923162317.

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1

Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen

Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119

PMCID:: PMC9231623

Abstract Article PDF–6.0M

Select item 934857618.

Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease

Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel

Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205

PMCID:: PMC9348576

Abstract Article PDF–3.0M

Select item 549522519.

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing

Teng Fei, Yiwen Chen, Tengfei Xiao, Wei Li, Laura Cato, Peng Zhang, Maura B. Cotter, Michaela Bowden, Rosina T. Lis, Shuang G. Zhao, Qiu Wu, Felix Y. Feng, Massimo Loda, Housheng Hansen He, X. Shirley Liu, Myles Brown

Proc Natl Acad Sci U S A. 2017 Jun 27; 114(26): E5207–E5215. Published online 2017 Jun 13. doi: 10.1073/pnas.1617467114

PMCID:: PMC5495225

Abstract Article PDF–1.3M

Select item 480585520.

Substrate-Trapped Interactors of PHD3 and FIH Cluster in Distinct Signaling Pathways

Javier Rodriguez, Ruth Pilkington, Amaya Garcia Munoz, Lan K. Nguyen, Nora Rauch, Susan Kennedy, Naser Monsefi, Ana Herrero, Cormac T. Taylor, Alex von Kriegsheim

Cell Rep. 2016 Mar 22; 14(11): 2745–2760. Published online 2016 Mar 10. doi: 10.1016/j.celrep.2016.02.043

PMCID:: PMC4805855

Abstract Article PDF–4.6M

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