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Select item 108869201.

Signaling Pathways of AXL Receptor Tyrosine Kinase Contribute to the Pathogenetic Mechanisms of Glioblastoma

Alberto Repici, Alessio Ardizzone, Fabiola De Luca, Lorenzo Colarossi, Angela Prestifilippo, Gabriele Pizzino, Irene Paterniti, Emanuela Esposito, Anna Paola Capra

Cells. 2024 Feb; 13(4): 361. Published online 2024 Feb 19. doi: 10.3390/cells13040361

PMCID:: PMC10886920

Abstract Article PDF–1.1M

Select item 102736962.

AXL in cancer: a modulator of drug resistance and therapeutic target

Yaoxiang Tang, Hongjing Zang, Qiuyuan Wen, Songqing Fan

J Exp Clin Cancer Res. 2023; 42: 148. Published online 2023 Jun 16. doi: 10.1186/s13046-023-02726-w

PMCID:: PMC10273696

Abstract Article PDF–2.1M

Select item 100577403.

Axl contributes to efficient migration and invasion of melanoma cells

Hanshuang Shao, Diana Teramae, Alan Wells

PLoS One. 2023; 18(3): e0283749. Published online 2023 Mar 29. doi: 10.1371/journal.pone.0283749

PMCID:: PMC10057740

Abstract Article PDF–1.7M

Select item 98996034.

High levels of AXL expression in untreated EGFR‐mutated non‐small cell lung cancer negatively impacts the use of osimertinib

Akihiro Yoshimura, Tadaaki Yamada, Masakuni Serizawa, Hisanori Uehara, Keiko Tanimura, Yusuke Okuma, Akito Fukuda, Satoshi Watanabe, Naoya Nishioka, Takayuki Takeda, Yusuke Chihara, Shinnosuke Takemoto, Taishi Harada, Osamu Hiranuma, Yukina Shirai, Takehito Shukuya, Akihiro Nishiyama, Yasuhiro Goto, Shinsuke Shiotsu, Kei Kunimasa, Kenji Morimoto, Yuki Katayama, Kenichi Suda, Tetsuya Mitsudomi, Seiji Yano, Hirotsugu Kenmotsu, Toshiaki Takahashi, Koichi Takayama

Cancer Sci. 2023 Feb; 114(2): 606–618. Published online 2022 Nov 11. doi: 10.1111/cas.15608

PMCID:: PMC9899603

Abstract Article PDF–1.8M

Select item 98336695.

Identification of AXL as a co-receptor for human parvovirus B19 infection of human erythroid progenitors

Kang Ning, Wei Zou, Peng Xu, Fang Cheng, Elizabeth Yan Zhang, Aaron Zhang-Chen, Steve Kleiboeker, Jianming Qiu

Sci Adv. 2023 Jan; 9(2): eade0869. Published online 2023 Jan 11. doi: 10.1126/sciadv.ade0869

PMCID:: PMC9833669

Abstract Article PDF–1.5M

Select item 92987786.

Increased serum AXL is associated with radiographic knee osteoarthritis severity

Shao Zhenghai

Int J Rheum Dis. 2022 Jan; 25(1): 32–37. Published online 2021 Nov 28. doi: 10.1111/1756-185X.14239

PMCID:: PMC9298778

Abstract Article PDF–683K

Select item 90401667.

AXL targeting restores PD-1 blockade sensitivity of STK11/LKB1 mutant NSCLC through expansion of TCF1⁺ CD8 T cells

Huiyu Li, Zhida Liu, Longchao Liu, Hongyi Zhang, Chuanhui Han, Luc Girard, Hyunsil Park, Anli Zhang, Chunbo Dong, Jianfeng Ye, Austin Rayford, Michael Peyton, Xiaoguang Li, Kimberley Avila, Xuezhi Cao, Shuiqing Hu, Md Maksudul Alam, Esra A. Akbay, Luisa M. Solis, Carmen Behrens, Sharia Hernandez-Ruiz, Wei Lu, Ignacio Wistuba, John V. Heymach, Michael Chisamore, David Micklem, Hani Gabra, Gro Gausdal, James B. Lorens, Bo Li, Yang-Xin Fu, John D. Minna, Rolf A. Brekken

Cell Rep Med. 2022 Mar 15; 3(3): 100554. Published online 2022 Mar 15. doi: 10.1016/j.xcrm.2022.100554

PMCID:: PMC9040166

Abstract Article PDF–3.9M

Select item 87083328.

AXL Knock-Out in SNU475 Hepatocellular Carcinoma Cells Provides Evidence for Lethal Effect Associated with G2 Arrest and Polyploidization

Tugce Batur, Ayse Argundogan, Umur Keles, Zeynep Mutlu, Hani Alotaibi, Serif Senturk, Mehmet Ozturk

Int J Mol Sci. 2021 Dec; 22(24): 13247. Published online 2021 Dec 9. doi: 10.3390/ijms222413247

PMCID:: PMC8708332

Abstract Article PDF–4.2M

Select item 85602829.

STAT1/SOCS1/3 Are Involved in the Inflammation-Regulating Effect of GAS6/AXL in Periodontal Ligament Cells Induced by Porphyromonas gingivalis Lipopolysaccharide In Vitro

Shengnan Zhang, Yingjun Liu, Xuekui Wang, Na An, Xiangying Ouyang

J Immunol Res. 2021; 2021: 9577695. Published online 2021 Oct 25. doi: 10.1155/2021/9577695

PMCID:: PMC8560282

Abstract Article PDF–1.0M

Select item 846240110.

Targeting AXL kinase sensitizes leukemic stem and progenitor cells to venetoclax treatment in acute myeloid leukemia

Xiaojia Niu, Katharina Rothe, Min Chen, Sarah Grasedieck, Rick Li, Sung-Eun Nam, Xiuyan Zhang, German E. Novakovskiy, Ye-Hyeon Ahn, Irina Maksakova, Shenshen Lai, Hong Zhang, Jun Yan, Hong Liu, Yun Zhao, Depei Wu, Yubin Ge, Wyeth W. Wasserman, Arefeh Rouhi, Florian Kuchenbauer, Calvin K. Yip, Zaihui Zhang, Xiaoyan Jiang

Blood. 2021 Jul 1; 137(26): 3641–3655. Prepublished online 2021 Mar 30. doi: 10.1182/blood.2020007651

PMCID:: PMC8462401

Abstract Article

Select item 821036111.

AXL receptor tyrosine kinase: a possible therapeutic target in acute promyelocytic leukemia

Mariam Fatima, Salik Javed Kakar, Fazal Adnan, Khalid Khan, Afsar Ali Mian, Dilawar Khan

BMC Cancer. 2021; 21: 713. Published online 2021 Jun 17. doi: 10.1186/s12885-021-08450-y

PMCID:: PMC8210361

Abstract Article PDF–1005K

Select item 816959912.

Bone Marrow-Derived AXL Tyrosine Kinase Promotes Mitogenic Crosstalk and Cardiac Allograft Vasculopathy

Kristofor Glinton, Matthew DeBerge, Emily Fisher, Samantha Schroth, Arjun Sinha, Jiao-Jing Wang, J. Andrew Wasserstrom, Mohammed Javeed Ansari, Zheng Jenny Zhang, Matthew Feinstein, Joseph R. Leventhal, Joseph M. Forbess, Jon Lomasney, Xunrong Luo, Edward B. Thorp

J Heart Lung Transplant. Author manuscript; available in PMC 2022 Jun 1.

Published in final edited form as: J Heart Lung Transplant. 2021 Jun; 40(6): 435–446. Published online 2021 Mar 13. doi: 10.1016/j.healun.2021.03.006

PMCID:: PMC8169599

Abstract Article PDF–1.7M

Select item 806565213.

Growth Arrest-Specific Factor 6 (GAS6) Is Increased in COVID-19 Patients and Predicts Clinical Outcome

Albert Morales, Silvia Rojo Rello, Helena Cristóbal, Aida Fiz-López, Elisa Arribas, Montserrat Marí, Anna Tutusaus, Paloma de la Cal-Sabater, Gerry A.F. Nicolaes, José T. Ortiz-Pérez, David Bernardo, Pablo García de Frutos

Biomedicines. 2021 Apr; 9(4): 335. Published online 2021 Mar 26. doi: 10.3390/biomedicines9040335

PMCID:: PMC8065652

Abstract Article PDF–23M

Select item 783862314.

Anexelekto (AXL) Increases Resistance to EGFR-TKI and Activation of AKT and ERK1/2 in Non-Small Cell Lung Cancer Cells

Yaqiong Tian, Zengli Zhang, Liyun Miao, Zhimin Yang, Jie Yang, Yinhua Wang, Danwen Qian, Hourong Cai, Yongsheng Wang

Oncol Res. 2016; 24(5): 295–303. Published online 2016 Sep 14. doi: 10.3727/096504016X14648701447814

PMCID:: PMC7838623

Abstract Article PDF–31M

Select item 769606115.

AXL Receptor in Breast Cancer: Molecular Involvement and Therapeutic Limitations

Italia Falcone, Fabiana Conciatori, Chiara Bazzichetto, Emilio Bria, Luisa Carbognin, Paola Malaguti, Gianluigi Ferretti, Francesco Cognetti, Michele Milella, Ludovica Ciuffreda

Int J Mol Sci. 2020 Nov; 21(22): 8419. Published online 2020 Nov 10. doi: 10.3390/ijms21228419

PMCID:: PMC7696061

Abstract Article PDF–1.7M

Select item 744260416.

AXL mediates cetuximab and radiation resistance through tyrosine 821 and the c-ABL kinase pathway in head and neck cancer

Nellie K McDaniel, Mari Iida, Kwangok P Nickel, Colin A Longhurst, Samantha R Fischbach, Tamara S Rodems, Carlene A Kranjac, Amber Y Bo, Qianyun Luo, Meghan M Gallagher, Noah B Welke, Kaitlyn R Mitchell, Alison E Schulz, Jaimee C Eckers, Rong Hu, Ravi Salgia, Seungpyo Hong, Justine Y Bruce, Randall J Kimple, Deric L Wheeler

Clin Cancer Res. Author manuscript; available in PMC 2021 Feb 15.

Published in final edited form as: Clin Cancer Res. 2020 Aug 15; 26(16): 4349–4359. Published online 2020 May 21. doi: 10.1158/1078-0432.CCR-19-3142

PMCID:: PMC7442604

Abstract Article PDF–1.4M

Select item 737385517.

Soluble Axl Is a Novel Diagnostic Biomarker of Hepatocellular Carcinoma in Chinese Patients with Chronic Hepatitis B Virus Infection

Xiaoting Song, Ailu Wu, Zhixiao Ding, Shixiong Liang, Chunyan Zhang

Cancer Res Treat. 2020 Jul; 52(3): 789–797. Published online 2020 Mar 5. doi: 10.4143/crt.2019.749

PMCID:: PMC7373855

Abstract Article PDF–542K

Select item 729930618.

Infection by Zika viruses requires the transmembrane protein AXL, endocytosis and low pH

Mirjana Persaud, Alicia Martinez-Lopez, Cindy Buffone, Steven A. Porcelli, Felipe Diaz-Griffero

Virology. Author manuscript; available in PMC 2020 Jun 17.

Published in final edited form as: Virology. 2018 May; 518: 301–312. Published online 2018 Mar 22. doi: 10.1016/j.virol.2018.03.009

PMCID:: PMC7299306

Abstract Article PDF–1.9M

Select item 719714319.

Axl receptor tyrosine kinase is a regulator of apolipoprotein E

Wenchen Zhao, Jianjia Fan, Iva Kulic, Cheryl Koh, Amanda Clark, Johan Meuller, Ola Engkvist, Samantha Barichievy, Carina Raynoschek, Ryan Hicks, Marcello Maresca, Qi Wang, Dean G. Brown, Alvin Lok, Cameron Parro, Jerome Robert, Hsien-Ya Chou, Andrea M. Zuhl, Michael W. Wood, Nicholas J. Brandon, Cheryl L. Wellington

Mol Brain. 2020; 13: 66. Published online 2020 May 4. doi: 10.1186/s13041-020-00609-1

PMCID:: PMC7197143

Abstract Article PDF–1.5M

Select item 701681820.

AXL Controls Directed Migration of Mesenchymal Triple-Negative Breast Cancer Cells

Olivier Zajac, Renaud Leclere, André Nicolas, Didier Meseure, Caterina Marchiò, Anne Vincent-Salomon, Sergio Roman-Roman, Marie Schoumacher, Thierry Dubois

Cells. 2020 Jan; 9(1): 247. Published online 2020 Jan 19. doi: 10.3390/cells9010247

PMCID:: PMC7016818

Abstract Article PDF–6.2M

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