U.S. flag

An official website of the United States government

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Links from Gene

Items: 1 to 20 of 40

1.
Deficiency for SAMHD1 activates MDA5 in a cGAS/STING-dependent manner
Tina Schumann, Santiago Costas Ramon, Nadja Schubert, Mohamad Aref Mayo, Melanie Hega, Katharina Isabell Maser, Servi-Remzi Ada, Lukas Sydow, Mona Hajikazemi, Markus Badstübner, Patrick Müller, Yan Ge, Farhad Shakeri, Andreas Buness, Benjamin Rupf, Stefan Lienenklaus, Barbara Utess, Lina Muhandes, Michael Haase, Luise Rupp, Marc Schmitz, Thomas Gramberg, Nicolas Manel, Gunther Hartmann, Thomas Zillinger, Hiroki Kato, Stefan Bauer, Alexander Gerbaulet, Katrin Paeschke, Axel Roers, Rayk Behrendt
J Exp Med. 2023 Jan 2; 220(1): e20220829. Published online 2022 Nov 8. doi: 10.1084/jem.20220829
PMCID:
PMC9648672
AbstractArticlePDF–5.7M
2.
SAMHD1 promotes the antiretroviral adaptive immune response in mice exposed to lipopolysaccharide
Bradley S. Barrett, David H. Nguyen, Joella Xu, Kejun Guo, Shravida Shetty, Sean T. Jones, Kaylee L. Mickens, Caitlin Shepard, Axel Roers, Rayk Behrendt, Li Wu, Baek Kim, Mario L. Santiago
J Immunol. Author manuscript; available in PMC 2022 Jul 15.
Published in final edited form as: J Immunol. 2022 Jan 15; 208(2): 444–453. Published online 2021 Dec 10. doi: 10.4049/jimmunol.2001389
PMCID:
PMC8755609
AbstractArticlePDF–1.7M
3.
Elimination of rNMPs from mitochondrial DNA has no effect on its stability
Paulina H. Wanrooij, Phong Tran, Liam J. Thompson, Gustavo Carvalho, Sushma Sharma, Katrin Kreisel, Clara Navarrete, Anna-Lena Feldberg, Danielle L. Watt, Anna Karin Nilsson, Martin K. M. Engqvist, Anders R. Clausen, Andrei Chabes
Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14306–14313. Published online 2020 Jun 8. doi: 10.1073/pnas.1916851117
PMCID:
PMC7322039
AbstractArticlePDF–1.4M
4.
Phosphorylation of mouse SAMHD1 regulates its restriction of human immunodeficiency virus type 1 infection, but not murine leukemia virus infection
Feifei Wang, Corine St. Gelais, Suresh de Silva, Hong Zhang, Yu Geng, Caitlin Shepard, Baek Kim, Jacob S. Yount, Li Wu
Virology. Author manuscript; available in PMC 2017 Jan 1.
Published in final edited form as: Virology. 2016 Jan; 487: 273–284. Published online 2015 Nov 12. doi: 10.1016/j.virol.2015.10.024
PMCID:
PMC4679491
AbstractArticlePDF–1.1M
5.
Phosphorylation of murine SAMHD1 regulates its antiretroviral activity
Sabine Wittmann, Rayk Behrendt, Kristin Eissmann, Bianca Volkmann, Dominique Thomas, Thomas Ebert, Alexandra Cribier, Monsef Benkirane, Veit Hornung, Nerea Ferreirós Bouzas, Thomas Gramberg
Retrovirology. 2015; 12: 103. Published online 2015 Dec 15. doi: 10.1186/s12977-015-0229-6
PMCID:
PMC4678485
AbstractArticlePDF–1.9M
6.
SAMHD1 Restricts HIV-1 Replication and Regulates Interferon Production in Mouse Myeloid Cells
Ruonan Zhang, Nicolin Bloch, Laura A. Nguyen, Baek Kim, Nathaniel R. Landau
PLoS One. 2014; 9(2): e89558. Published online 2014 Feb 19. doi: 10.1371/journal.pone.0089558
PMCID:
PMC3929709
AbstractArticlePDF–1.8M
7.
The SAMHD1 knockout mouse model: in vivo veritas?
Ferdinand Roesch, Olivier Schwartz
EMBO J. 2013 Sep 11; 32(18): 2427–2429. Published online 2013 Aug 20. doi: 10.1038/emboj.2013.190
PMCID:
PMC3770955
AbstractArticlePDF–203K
8.
SAMHD1 Attenuates Acute Inflammation by Maintaining Mitochondrial Function in Macrophages via Interaction with VDAC1
Bowen Xu, Qianyi Sui, Han Hu, Xiangjia Hu, Xuchang Zhou, Cheng Qian, Nan Li
Int J Mol Sci. 2023 May; 24(9): 7888. Published online 2023 Apr 26. doi: 10.3390/ijms24097888
PMCID:
PMC10177872
AbstractArticlePDF–5.8M
9.
Single-epitope T cell–based vaccine protects against SARS-CoV-2 infection in a preclinical animal model
Takuya Tada, Ju-Yi Peng, Belinda M. Dcosta, Nathaniel R. Landau
JCI Insight. 2023 Apr 10; 8(7): e167306. Published online 2023 Apr 10. doi: 10.1172/jci.insight.167306
PMCID:
PMC10132166
AbstractArticlePDF–8.6M
10.
SAMHD1 Limits the Efficacy of Forodesine in Leukemia by Protecting Cells against the Cytotoxicity of dGTP
Tamara Davenne, Jenny Klintman, Sushma Sharma, Rachel E. Rigby, Henry T.W. Blest, Chiara Cursi, Anne Bridgeman, Bernadeta Dadonaite, Kim De Keersmaecker, Peter Hillmen, Andrei Chabes, Anna Schuh, Jan Rehwinkel
Cell Rep. 2020 May 12; 31(6): 107640. Published online 2020 May 12. doi: 10.1016/j.celrep.2020.107640
PMCID:
PMC7225753
AbstractArticle
11.
SAMHD1 suppresses innate immune responses to viral infections and inflammatory stimuli by inhibiting the NF-κB and interferon pathways
Shuliang Chen, Serena Bonifati, Zhihua Qin, Corine St. Gelais, Karthik M. Kodigepalli, Bradley S. Barrett, Sun Hee Kim, Jenna M. Antonucci, Katherine J. Ladner, Olga Buzovetsky, Kirsten M. Knecht, Yong Xiong, Jacob S. Yount, Denis C. Guttridge, Mario L. Santiago, Li Wu
Proc Natl Acad Sci U S A. 2018 Apr 17; 115(16): E3798–E3807. Published online 2018 Apr 2. doi: 10.1073/pnas.1801213115
PMCID:
PMC5910870
AbstractArticlePDF–1.4M
12.
The SAM domain of mouse SAMHD1 is critical for its activation and regulation
Olga Buzovetsky, Chenxiang Tang, Kirsten M. Knecht, Jenna M. Antonucci, Li Wu, Xiaoyun Ji, Yong Xiong
Nat Commun. 2018; 9: 411. Published online 2018 Jan 29. doi: 10.1038/s41467-017-02783-8
PMCID:
PMC5788916
AbstractArticlePDF–1.8M
13.
A G1‐like state allows HIV‐1 to bypass SAMHD1 restriction in macrophages
Petra Mlcochova, Katherine A Sutherland, Sarah A Watters, Cosetta Bertoli, Rob AM de Bruin, Jan Rehwinkel, Stuart J Neil, Gina M Lenzi, Baek Kim, Asim Khwaja, Matthew C Gage, Christiana Georgiou, Alexandra Chittka, Simon Yona, Mahdad Noursadeghi, Greg J Towers, Ravindra K Gupta
EMBO J. 2017 Mar 1; 36(5): 604–616. Published online 2017 Jan 25. doi: 10.15252/embj.201696025
PMCID:
PMC5331754
AbstractArticlePDF–2.7M
14.
A Highly Active Isoform of Lentivirus Restriction Factor SAMHD1 in Mouse
Nicolin Bloch, Sabine Gläsker, Poojitha Sitaram, Henning Hofmann, Caitlin N. Shepard, Megan L. Schultz, Baek Kim, Nathaniel R. Landau
J Biol Chem. 2017 Jan 20; 292(3): 1068–1080. Published online 2016 Dec 5. doi: 10.1074/jbc.M116.743740
PMCID:
PMC5247641
AbstractArticlePDF–2.7M
15.
Heterozygous colon cancer-associated mutations of SAMHD1 have functional significance
Matilda Rentoft, Kristoffer Lindell, Phong Tran, Anna Lena Chabes, Robert J. Buckland, Danielle L. Watt, Lisette Marjavaara, Anna Karin Nilsson, Beatrice Melin, Johan Trygg, Erik Johansson, Andrei Chabes
Proc Natl Acad Sci U S A. 2016 Apr 26; 113(17): 4723–4728. Published online 2016 Apr 11. doi: 10.1073/pnas.1519128113
Correction in:
Proc Natl Acad Sci U S A. 2019 Mar 5; 116(10): 4744.
PMCID:
PMC4855590
AbstractArticlePDF–686K
16.
Allosteric Regulation of the Human and Mouse Deoxyribonucleotide Triphosphohydrolase Sterile α-Motif/Histidine-Aspartate Domain-containing Protein 1 (SAMHD1)
Cristina Miazzi, Paola Ferraro, Giovanna Pontarin, Chiara Rampazzo, Peter Reichard, Vera Bianchi
J Biol Chem. 2014 Jun 27; 289(26): 18339–18346. Published online 2014 May 14. doi: 10.1074/jbc.M114.571091
PMCID:
PMC4140260
AbstractArticlePDF–1.1M
17.
Modulation of LINE-1 and Alu/SVA Retrotransposition by Aicardi-Goutières Syndrome-Related SAMHD1
Ke Zhao, Juan Du, Xue Han, John L. Goodier, Peng Li, Xiaohong Zhou, Wei Wei, Sean L. Evans, Linzhang Li, Wenyan Zhang, Ling E. Cheung, Guanjun Wang, Haig H. Kazazian, Jr., Xiao-Fang Yu
Cell Rep. Author manuscript; available in PMC 2014 Sep 26.
Published in final edited form as: Cell Rep. 2013 Sep 26; 4(6): 1108–1115. Published online 2013 Sep 12. doi: 10.1016/j.celrep.2013.08.019
PMCID:
PMC3988314
AbstractArticlePDF–834K
18.
Vectored immunoprophylaxis and treatment of SARS-CoV-2 infection in a preclinical model
Takuya Tada, Julia Minnee, Nathaniel R. Landau
Proc Natl Acad Sci U S A. 2023 Jun 6; 120(23): e2303509120. Published online 2023 May 30. doi: 10.1073/pnas.2303509120
PMCID:
PMC10266030
AbstractArticlePDF–6.9M
19.
SAMHD1-dependent retroviral control and escape in mice
Jan Rehwinkel, Jonathan Maelfait, Anne Bridgeman, Rachel Rigby, Bruce Hayward, Rachel A Liberatore, Paul D Bieniasz, Greg J Towers, Luis F Moita, Yanick J Crow, David T Bonthron, Caetano Reis e Sousa
EMBO J. 2013 Sep 11; 32(18): 2454–2462. Published online 2013 Jul 19. doi: 10.1038/emboj.2013.163
PMCID:
PMC3770946
AbstractArticlePDF–651K
20.
Functional Analysis of the Relationship between Vpx and the Restriction Factor SAMHD1
Gregory Berger, Jocelyn Turpin, Stéphanie Cordeil, Kevin Tartour, Xuan-Nhi Nguyen, Renaud Mahieux, Andrea Cimarelli
J Biol Chem. 2012 Nov 30; 287(49): 41210–41217. Published online 2012 Oct 17. doi: 10.1074/jbc.M112.403816
PMCID:
PMC3510820
AbstractArticlePDF–1.1M

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Filter your results:

Find related data

Recent activity

Clear Turn Off Turn On

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
You are here: NCBI > Literature > PubMed Central (PMC)
Support Center