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Items: 1 to 20 of 29

1.
Brown adipose TRX2 deficiency activates mtDNA-NLRP3 to impair thermogenesis and protect against diet-induced insulin resistance
Yanrui Huang, Jenny H. Zhou, Haifeng Zhang, Alberto Canfran-Duque, Abhishek K. Singh, Rachel J. Perry, Gerald I. Shulman, Carlos Fernandez-Hernando, Wang Min
J Clin Invest. 2022 May 2; 132(9): e148852. Published online 2022 May 2. doi: 10.1172/JCI148852
PMCID:
PMC9057632
AbstractArticlePDF–30M
2.
Mitophagy-mediated adipose inflammation contributes to type 2 diabetes with hepatic insulin resistance
Feng He, Yanrui Huang, Zhi Song, Huanjiao Jenny Zhou, Haifeng Zhang, Rachel J. Perry, Gerald I. Shulman, Wang Min
J Exp Med. 2021 Mar 1; 218(3): e20201416. Published online 2020 Dec 14. doi: 10.1084/jem.20201416
PMCID:
PMC7927432
AbstractArticlePDF–8.5M
3.
Txn2 haplodeficiency does not affect cochlear antioxidant defenses or accelerate the progression of cochlear cell loss or hearing loss across the lifespan
Mi-Jung Kim, Chul Han, Karessa White, Hyo-Jin Park, Dalian Ding, Kevin Boyd, Christina Rothenberger, Upal Bose, Peter Carmichael, Paul J. Linser, Masaru Tanokura, Richard Salvi, Shinichi Someya
Exp Gerontol. Author manuscript; available in PMC 2021 Nov 1.
Published in final edited form as: Exp Gerontol. 2020 Nov; 141: 111078. Published online 2020 Aug 28. doi: 10.1016/j.exger.2020.111078
PMCID:
PMC7680416
AbstractArticlePDF–2.9M
4.
Thidoredxin-2 overexpression fails to rescue chronic high calorie diet induced hippocampal dysfunction
Yong Liu, Ying Yang, Hui Dong, Roy G. Cutler, Randy Strong, Mark P. Mattson
Exp Neurol. Author manuscript; available in PMC 2017 Jan 1.
Published in final edited form as: Exp Neurol. 2016 Jan; 275(0 1): 126–132. Published online 2015 Oct 22. doi: 10.1016/j.expneurol.2015.10.002
PMCID:
PMC4688172
AbstractArticlePDF–778K
5.
Endothelial-specific expression of mitochondrial thioredoxin promotes ischemia-mediated arteriogenesis and angiogenesis
Shengchuan Dai, Yun He, Haifeng Zhang, Luyang Yu, Ting Wan, Zhe Xu, Dennis Jones, Hong Chen, Wang Min
Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2009 Aug 28.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2009 Apr; 29(4): 495–502. Published online 2009 Jan 15. doi: 10.1161/ATVBAHA.108.180349
PMCID:
PMC2734510
AbstractArticlePDF–2.0M
6.
Identification of Thioredoxin-2 as a Regulator of the Mitochondrial Permeability Transition
Min He, Jiyang Cai, Young-Mi Go, Jennifer M. Johnson, W. David Martin, Jason M. Hansen, Dean P. Jones
Toxicol Sci. 2008 Sep; 105(1): 44–50. Published online 2008 Jun 11. doi: 10.1093/toxsci/kfn116
PMCID:
PMC2734306
AbstractArticlePDF–193K
7.
The Absence of Mitochondrial Thioredoxin 2 Causes Massive Apoptosis, Exencephaly, and Early Embryonic Lethality in Homozygous Mice
Larisa Nonn, Ryan R. Williams, Robert P. Erickson, Garth Powis
Mol Cell Biol. 2003 Feb; 23(3): 916–922. doi: 10.1128/MCB.23.3.916-922.2003
PMCID:
PMC140716
AbstractArticlePDF–550K
8.
scAAV2-Mediated Expression of Thioredoxin 2 and C3 Transferase Prevents Retinal Ganglion Cell Death and Lowers Intraocular Pressure in a Mouse Model of Glaucoma
Hee Jong Kim, Seho Cha, Jun-Sub Choi, Joo Yong Lee, Ko Eun Kim, Jin Kwon Kim, Jin Kim, Seo Yun Moon, Steven Hyun Seung Lee, Keerang Park, So-Yoon Won
Int J Mol Sci. 2023 Nov; 24(22): 16253. Published online 2023 Nov 13. doi: 10.3390/ijms242216253
PMCID:
PMC10671512
AbstractArticlePDF–2.7M
9.
Thioredoxin-2 Inhibits Mitochondrial ROS Generation and ASK1 Activity to Maintain Cardiac Function
Qunhua Huang, Huanjiao Jenny Zhou, Haifeng Zhang, Yan Huang, Ford Hinojosa-Kirschenbaum, Peidong Fan, Lina Yao, Luiz Belardinelli, George Tellides, Frank J. Giordano, Grant R. Budas, Wang Min
Circulation. Author manuscript; available in PMC 2016 Mar 24.
Published in final edited form as: Circulation. 2015 Mar 24; 131(12): 1082–1097. Published online 2015 Jan 27. doi: 10.1161/CIRCULATIONAHA.114.012725
PMCID:
PMC4374031
AbstractArticlePDF–2.9M
10.
Hepatic Oxidative Stress in Fructose-Induced Fatty Liver Is Not Caused by Sulfur Amino Acid Insufficiency
Sachin S. Kunde, James R. Roede, Miriam B. Vos, Michael L. Orr, Young-Mi Go, Youngja Park, Thomas R. Ziegler, Dean P. Jones
Nutrients. 2011 Nov; 3(11): 987–1002. Published online 2011 Nov 18. doi: 10.3390/nu3110987
PMCID:
PMC3257721
AbstractArticlePDF–921K
11.
Zbtb16 increases susceptibility of atrial fibrillation in type 2 diabetic mice via Txnip-Trx2 signaling
Zhi-Xing Wei, Xing-Xing Cai, Yu-Dong Fei, Qian Wang, Xiao-Liang Hu, Cheng Li, Jian-Wen Hou, Yu-Li Yang, Tai-Zhong Chen, Xiao-Lei Xu, Yue-Peng Wang, Yi-Gang Li
Cell Mol Life Sci. 2024 Dec; 81(1): 88. Published online 2024 Feb 13. doi: 10.1007/s00018-024-05125-2
PMCID:
PMC10864461
AbstractArticlePDF–9.9M
12.
Mitochondrial dysfunction induces ALK5-SMAD2-mediated hypovascularization and arteriovenous malformations in mouse retinas
Haifeng Zhang, Busu Li, Qunhua Huang, Francesc López-Giráldez, Yoshiaki Tanaka, Qun Lin, Sameet Mehta, Guilin Wang, Morven Graham, Xinran Liu, In-Hyun Park, Anne Eichmann, Wang Min, Jenny Huanjiao Zhou
Nat Commun. 2022; 13: 7637. Published online 2022 Dec 10. doi: 10.1038/s41467-022-35262-w
PMCID:
PMC9741628
AbstractArticlePDF–16M
13.
Both Thioredoxin 2 and Glutaredoxin 2 Contribute to the Reduction of the Mitochondrial 2-Cys Peroxiredoxin Prx3
Eva-Maria Hanschmann, Maria Elisabet Lönn, Lena Dorothee Schütte, Maria Funke, José R. Godoy, Susanne Eitner, Christoph Hudemann, Christopher Horst Lillig
J Biol Chem. 2010 Dec 24; 285(52): 40699–40705. Published online 2010 Oct 7. doi: 10.1074/jbc.M110.185827
PMCID:
PMC3003369
AbstractArticlePDF–1.8M
14.
SirT1 Regulation of Antioxidant Genes Is Dependent on the Formation of a FoxO3a/PGC-1α Complex
Yolanda Olmos, Francisco J. Sánchez-Gómez, Brigitte Wild, Nieves García-Quintans, Sofía Cabezudo, Santiago Lamas, María Monsalve
Antioxid Redox Signal. 2013 Nov 1; 19(13): 1507–1521. doi: 10.1089/ars.2012.4713
PMCID:
PMC3797451
AbstractArticlePDF–1.0M
15.
Increased Muscle Stress-Sensitivity Induced by Selenoprotein N Inactivation in Mouse: A Mammalian Model for SEPN1-Related Myopathy
Mathieu Rederstorff, Perrine Castets, Sandrine Arbogast, Jeanne Lainé, Stéphane Vassilopoulos, Maud Beuvin, Odile Dubourg, Alban Vignaud, Arnaud Ferry, Alain Krol, Valérie Allamand, Pascale Guicheney, Ana Ferreiro, Alain Lescure
PLoS One. 2011; 6(8): e23094. Published online 2011 Aug 8. doi: 10.1371/journal.pone.0023094
PMCID:
PMC3152547
AbstractArticlePDF–3.4M
16.
ANKRD13a controls early cell-death checkpoint by interacting with RIP1 independent of NF-κB
Minho Won, Kyeong Ah Park, Sup Kim, Eunjin Ju, Youngbok Ko, Heonjong Yoo, Hyunju Ro, Jaeseob Lee, Junseo Oh, Eun Gyo Lee, Sang Yean Kim, Suk Woo Nam, Han-Ming Shen, Min-Kyung Yeo, Jin Man Kim, Gang Min Hur
Cell Death Differ. 2022 Jun; 29(6): 1152–1163. Published online 2021 Nov 27. doi: 10.1038/s41418-021-00906-9
PMCID:
PMC9177599
AbstractArticlePDF–3.4M
17.
A mitochondrial protein compendium elucidates complex I disease biology
David J. Pagliarini, Sarah E. Calvo, Betty Chang, Sunil A. Sheth, Scott B. Vafai, Shao-En Ong, Geoffrey A. Walford, Canny Sugiana, Avihu Boneh, William K. Chen, David E. Hill, Marc Vidal, James G. Evans, David R. Thorburn, Steven A. Carr, Vamsi K. Mootha
Cell. Author manuscript; available in PMC 2009 Nov 18.
Published in final edited form as: Cell. 2008 Jul 11; 134(1): 112–123. doi: 10.1016/j.cell.2008.06.016
PMCID:
PMC2778844
AbstractArticlePDF–1.2M
18.
A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome
Jens Hansen, Thomas Floss, Petra Van Sloun, Ernst-Martin Füchtbauer, Franz Vauti, Hans-Hennig Arnold, Frank Schnütgen, Wolfgang Wurst, Harald von Melchner, Patricia Ruiz
Proc Natl Acad Sci U S A. 2003 Aug 19; 100(17): 9918–9922. Published online 2003 Aug 6. doi: 10.1073/pnas.1633296100
PMCID:
PMC187885
AbstractArticlePDF–287K
19.
BGEM: An In Situ Hybridization Database of Gene Expression in the Embryonic and Adult Mouse Nervous System
Susan Magdaleno, Patricia Jensen, Craig L Brumwell, Anna Seal, Karen Lehman, Andrew Asbury, Tony Cheung, Tommie Cornelius, Diana M Batten, Christopher Eden, Shannon M Norland, Dennis S Rice, Nilesh Dosooye, Sundeep Shakya, Perdeep Mehta, Tom Curran
PLoS Biol. 2006 Apr; 4(4): e86. Published online 2006 Mar 28. doi: 10.1371/journal.pbio.0040086
PMCID:
PMC1413568
ArticlePDF–99K
20.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M

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