PMC Links for Gene (Select 56624) - PMC

Select item 63475321.

Neutral Ceramidase: advances in mechanisms, cell regulation, and roles in cancer

Nicolas Coant, Yusuf A. Hannun

Adv Biol Regul. Author manuscript; available in PMC 2020 Jan 1.

Published in final edited form as: Adv Biol Regul. 2019 Jan; 71: 141–146. Published online 2018 Oct 26. doi: 10.1016/j.jbior.2018.10.005

PMCID:: PMC6347532

Abstract Article PDF–530K

Select item 37623222.

Transcriptional Regulation of the Human Neutral Ceramidase Gene

Sean M. O’Neill, Jong K. Yun, Todd E. Fox, Mark Kester

Arch Biochem Biophys. Author manuscript; available in PMC 2013 Sep 4.

Published in final edited form as: Arch Biochem Biophys. 2011 Jul; 511(0): 21–30. Published online 2011 Apr 22. doi: 10.1016/j.abb.2011.04.012

PMCID:: PMC3762322

Abstract Article PDF–4.0M

Select item 62109013.

Functions of neutral ceramidase in the Golgi apparatus

Wataru Sakamoto, Nicolas Coant, Daniel Canals, Lina M. Obeid, Yusuf A. Hannun

J Lipid Res. 2018 Nov; 59(11): 2116–2125. Published online 2018 Aug 28. doi: 10.1194/jlr.M088187

PMCID:: PMC6210901

Abstract Article PDF–1.2M

Select item 48300884.

Structural basis for ceramide recognition and hydrolysis by human Neutral Ceramidase

Michael V. Airola, William J. Allen, Michael J. Pulkoski-Gross, Lina M. Obeid, Robert C. Rizzo, Yusuf A. Hannun

Structure. Author manuscript; available in PMC 2016 Aug 4.

Published in final edited form as: Structure. 2015 Aug 4; 23(8): 1482–1491. Published online 2015 Jul 16. doi: 10.1016/j.str.2015.06.013

PMCID:: PMC4830088

Abstract Article PDF–1.6M

Select item 37625655.

AP-1 Binding Transcriptionally Regulates Human Neutral Ceramidase

Sean M. O’Neill, Kristy L. Houck, Jong K. Yun, Todd E. Fox, Mark Kester

Arch Biochem Biophys. Author manuscript; available in PMC 2013 Sep 4.

Published in final edited form as: Arch Biochem Biophys. 2011 Jul; 511(0): 31–39. Published online 2011 Apr 21. doi: 10.1016/j.abb.2011.04.009

PMCID:: PMC3762565

Abstract Article PDF–2.7M

Select item 26938546.

A Study on Altered Expression of Serine Palmitoyltransferase and Ceramidase in Psoriatic Skin Lesion

Kyung-Kook Hong, Hee-Ryung Cho, Won-Chul Ju, Yunhi Cho, Nack-In Kim

J Korean Med Sci. 2007 Oct; 22(5): 862–867. Published online 2007 Oct 31. doi: 10.3346/jkms.2007.22.5.862

PMCID:: PMC2693854

Abstract Article PDF–104K

Select item 27884357.

Downregulation of Neutral Ceramidase by Gemcitabine: Implications for Cell Cycle Regulation

Bill X. Wu, Youssef H. Zeidan, Yusuf A. Hannun

Biochim Biophys Acta. Author manuscript; available in PMC 2010 Aug 1.

Published in final edited form as: Biochim Biophys Acta. 2009 Aug; 1791(8): 730–739. Published online 2009 Apr 2. doi: 10.1016/j.bbalip.2009.03.012

PMCID:: PMC2788435

Abstract Article PDF–2.2M

Select item 79467768.

Asah2 represses the p53-Hmox1 axis to protect myeloid-derived suppressor cells from ferroptosis

Huabin Zhu, John Klement, Chunwan Lu, Priscilla S. Redd, Dafeng Yang, Alyssa D. Smith, Dakota B. Poschel, Juan Zou, Ding Liu, Peng George Wang, David Ostrov, Nicolas Coant, Yusuf A. Hannun, Aaron H. Colby, Mark W. Grinstaff, Kebin Liu

J Immunol. Author manuscript; available in PMC 2022 Mar 15.

Published in final edited form as: J Immunol. 2021 Mar 15; 206(6): 1395–1404. Published online 2021 Feb 5. doi: 10.4049/jimmunol.2000500

PMCID:: PMC7946776

Abstract Article PDF–1.7M

Select item 39617639.

Adiponectin Inhibits TNF-α-Induced Vascular Inflammatory Response via Caveolin-Mediated Ceramidase Recruitment and Activation

Yajing Wang, Xiaoliang Wang, Wayne Bond Lau, Yuexin Yuan, David Booth, Jing-Jing Li, Rosario Scalia, Kyle Preston, Erhe Gao, Walter Koch, Xin-Liang Ma

Circ Res. Author manuscript; available in PMC 2015 Feb 28.

Published in final edited form as: Circ Res. 2014 Feb 28; 114(5): 792–805. Published online 2014 Jan 7. doi: 10.1161/CIRCRESAHA.114.302439

PMCID:: PMC3961763

Abstract Article PDF–3.2M

Select item 136072110.

Identification of a novel amidase motif in neutral ceramidase

Sehamuddin Galadari, Bill X. Wu, Cungui Mao, Patrick Roddy, Samer El Bawab, Yusuf A. Hannun

Biochem J. 2006 Feb 1; 393(Pt 3): 687–695. Prepublished online 2005 Oct 18. Published online 2006 Jan 13. doi: 10.1042/BJ20050682

PMCID:: PMC1360721

Abstract Article PDF–547K

Select item 366371211.

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations

Anna Köttgen, Eva Albrecht, Alexander Teumer, Veronique Vitart, Jan Krumsiek, Claudia Hundertmark, Giorgio Pistis, Daniela Ruggiero, Conall M O’Seaghdha, Toomas Haller, Qiong Yang, Toshiko Tanaka, Andrew D Johnson, Zoltán Kutalik, Albert V Smith, Julia Shi, Maksim Struchalin, Rita P S Middelberg, Morris J Brown, Angelo L Gaffo, Nicola Pirastu, Guo Li, Caroline Hayward, Tatijana Zemunik, Jennifer Huffman, Loic Yengo, Jing Hua Zhao, Ayse Demirkan, Mary F Feitosa, Xuan Liu, Giovanni Malerba, Lorna M Lopez, Pim van der Harst, Xinzhong Li, Marcus E Kleber, Andrew A Hicks, Ilja M Nolte, Asa Johansson, Federico Murgia, Sarah H Wild, Stephan J L Bakker, John F Peden, Abbas Dehghan, Maristella Steri, Albert Tenesa, Vasiliki Lagou, Perttu Salo, Massimo Mangino, Lynda M Rose, Terho Lehtimäki, Owen M Woodward, Yukinori Okada, Adrienne Tin, Christian Müller, Christopher Oldmeadow, Margus Putku, Darina Czamara, Peter Kraft, Laura Frogheri, Gian Andri Thun, Anne Grotevendt, Gauti Kjartan Gislason, Tamara B Harris, Lenore J Launer, Patrick McArdle, Alan R Shuldiner, Eric Boerwinkle, Josef Coresh, Helena Schmidt, Michael Schallert, Nicholas G Martin, Grant W Montgomery, Michiaki Kubo, Yusuke Nakamura, Toshihiro Tanaka, Patricia B Munroe, Nilesh J Samani, David R Jacobs, Jr, Kiang Liu, Pio D’Adamo, Sheila Ulivi, Jerome I Rotter, Bruce M Psaty, Peter Vollenweider, Gerard Waeber, Susan Campbell, Olivier Devuyst, Pau Navarro, Ivana Kolcic, Nicholas Hastie, Beverley Balkau, Philippe Froguel, Tõnu Esko, Andres Salumets, Kay Tee Khaw, Claudia Langenberg, Nicholas J Wareham, Aaron Isaacs, Aldi Kraja, Qunyuan Zhang, Philipp S Wild, Rodney J Scott, Elizabeth G Holliday, Elin Org, Margus Viigimaa, Stefania Bandinelli, Jeffrey E Metter, Antonio Lupo, Elisabetta Trabetti, Rossella Sorice, Angela Döring, Eva Lattka, Konstantin Strauch, Fabian Theis, Melanie Waldenberger, H-Erich Wichmann, Gail Davies, Alan J Gow, Marcel Bruinenberg, LifeLines Cohort Study, Ronald P Stolk, Jaspal S Kooner, Weihua Zhang, Bernhard R Winkelmann, Bernhard O Boehm, Susanne Lucae, Brenda W Penninx, Johannes H Smit, Gary Curhan, Poorva Mudgal, Robert M Plenge, Laura Portas, Ivana Persico, Mirna Kirin, James F Wilson, Irene Mateo Leach, Wiek H van Gilst, Anuj Goel, Halit Ongen, Albert Hofman, Fernando Rivadeneira, Andre G Uitterlinden, Medea Imboden, Arnold von Eckardstein, Francesco Cucca, Ramaiah Nagaraja, Maria Grazia Piras, Matthias Nauck, Claudia Schurmann, Kathrin Budde, Florian Ernst, Susan M Farrington, Evropi Theodoratou, Inga Prokopenko, Michael Stumvoll, Antti Jula, Markus Perola, Veikko Salomaa, So-Youn Shin, Tim D Spector, Cinzia Sala, Paul M Ridker, Mika Kähönen, Jorma Viikari, Christian Hengstenberg, Christopher P Nelson, CARDIoGRAM Consortium, DIAGRAM Consortium, ICBP Consortium, MAGIC Consortium, James F Meschia, Michael A Nalls, Pankaj Sharma, Andrew B Singleton, Naoyuki Kamatani, Tanja Zeller, Michel Burnier, John Attia, Maris Laan, Norman Klopp, Hans L Hillege, Stefan Kloiber, Hyon Choi, Mario Pirastu, Silvia Tore, Nicole M Probst-Hensch, Henry Völzke, Vilmundur Gudnason, Afshin Parsa, Reinhold Schmidt, John B Whitfield, Myriam Fornage, Paolo Gasparini, David S Siscovick, Ozren Polašek, Harry Campbell, Igor Rudan, Nabila Bouatia-Naji, Andres Metspalu, Ruth J F Loos, Cornelia M van Duijn, Ingrid B Borecki, Luigi Ferrucci, Giovanni Gambaro, Ian J Deary, Bruce H R Wolffenbuttel, John C Chambers, Winfried März, Peter P Pramstaller, Harold Snieder, Ulf Gyllensten, Alan F Wright, Gerjan Navis, Hugh Watkins, Jacqueline C M Witteman, Serena Sanna, Sabine Schipf, Malcolm G Dunlop, Anke Tönjes, Samuli Ripatti, Nicole Soranzo, Daniela Toniolo, Daniel I Chasman, Olli Raitakari, W H Linda Kao, Marina Ciullo, Caroline S Fox, Mark Caulfield, Murielle Bochud, Christian Gieger

Nat Genet. Author manuscript; available in PMC 2013 Aug 1.

Published in final edited form as: Nat Genet. 2013 Feb; 45(2): 145–154. Published online 2012 Dec 23. doi: 10.1038/ng.2500

PMCID:: PMC3663712

Abstract Article PDF–1.2M

Select item 381232412.

Genome-wide association analyses suggest NELL1 influences adverse metabolic response to HCTZ in African Americans

J L Del-Aguila, A L Beitelshees, R M Cooper-DeHoff, A B Chapman, J G Gums, K Bailey, Y Gong, S T Turner, J A Johnson, E Boerwinkle

Pharmacogenomics J. 2014 Feb; 14(1): 35–40. Published online 2013 Feb 12. doi: 10.1038/tpj.2013.3

PMCID:: PMC3812324

Abstract Article PDF–662K

Select item 138022513.

A Scan of Chromosome 10 Identifies a Novel Locus Showing Strong Association with Late-Onset Alzheimer Disease

Andrew Grupe, Yonghong Li, Charles Rowland, Petra Nowotny, Anthony L. Hinrichs, Scott Smemo, John S. K. Kauwe, Taylor J. Maxwell, Sara Cherny, Lisa Doil, Kristina Tacey, Ryan van Luchene, Amanda Myers, Fabienne Wavrant-De Vrièze, Mona Kaleem, Paul Hollingworth, Luke Jehu, Catherine Foy, Nicola Archer, Gillian Hamilton, Peter Holmans, Chris M. Morris, Joseph Catanese, John Sninsky, Thomas J. White, John Powell, John Hardy, Michael O’Donovan, Simon Lovestone, Lesley Jones, John C. Morris, Leon Thal, Michael Owen, Julie Williams, Alison Goate

Am J Hum Genet. 2006 Jan; 78(1): 78–88. Published online 2005 Nov 15. doi: 10.1086/498851

PMCID:: PMC1380225

Abstract Article PDF–329K

Select item 294347614.

Genetic Variants in Nuclear-Encoded Mitochondrial Genes Influence AIDS Progression

Sher L. Hendrickson, James A. Lautenberger, Leslie Wei Chinn, Michael Malasky, Efe Sezgin, Lawrence A. Kingsley, James J. Goedert, Gregory D. Kirk, Edward D. Gomperts, Susan P. Buchbinder, Jennifer L. Troyer, Stephen J. O'Brien

PLoS One. 2010; 5(9): e12862. Published online 2010 Sep 21. doi: 10.1371/journal.pone.0012862

PMCID:: PMC2943476

Abstract Article PDF–461K

Select item 816503015.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011