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1.
UBQLN4 promotes the proliferation and invasion of non-small cell lung cancer cell by regulating PI3K/AKT pathway
Li He, Heng Chen, Bin Ruan, Li He, Ming Luo, Yulun Fu, Rui Zou
J Cancer Res Clin Oncol. 2024; 150(7): 335. Published online 2024 Jul 6. doi: 10.1007/s00432-024-05862-8
PMCID:
PMC11226510
AbstractArticlePDF–1.9M
2.
Genomic Amplification of UBQLN4 Is a Prognostic and Treatment Resistance Factor
Yuta Kobayashi, Matias A. Bustos, Yoshiaki Shoji, Ron D. Jachimowicz, Yosef Shiloh, Dave S. B. Hoon
Cells. 2022 Oct; 11(20): 3311. Published online 2022 Oct 21. doi: 10.3390/cells11203311
PMCID:
PMC9600423
AbstractArticlePDF–5.2M
3.
Ubqln4 Facilitates Endoplasmic Reticulum-to-Cytosol Escape of a Nonenveloped Virus during Infection
Xiaofang Liu, Billy Tsai
J Virol. 2020 Jun; 94(11): e00103-20. Prepublished online 2020 Mar 11. Published online 2020 May 18. doi: 10.1128/JVI.00103-20
PMCID:
PMC7269444
AbstractArticlePDF–1.3M
4.
Overexpression of the Ubiquilin-4 (UBQLN4) is Associated with Cell Cycle Arrest and Apoptosis in Human Normal Gastric Epithelial Cell Lines GES-1 Cells by Activation of the ERK Signaling Pathway
Shengkai Huang, Xin Dong, Jia Wang, Jie Ding, Yan Li, Dongdong Li, Hong Lin, Wenjie Wang, Mei Zhao, Qing Chang, Ning Zhou, Wei Cui, Changzhi Huang
Med Sci Monit. 2018; 24: 3564–3570. Published online 2018 May 28. doi: 10.12659/MSM.909621
PMCID:
PMC6004079
AbstractArticlePDF–1.1M
5.
A novel ALS-associated variant in UBQLN4 regulates motor axon morphogenesis
Brittany M Edens, Jianhua Yan, Nimrod Miller, Han-Xiang Deng, Teepu Siddique, Yongchao C Ma
eLife. 2017; 6: e25453. Published online 2017 May 2. doi: 10.7554/eLife.25453
PMCID:
PMC5451210
AbstractArticlePDF–2.2M
6.
Albendazole induces immunotherapy response by facilitating ubiquitin-mediated PD-L1 degradation
Lin Zhu, Xinwei Kuang, Guanxiong Zhang, Long Liang, Dandan Liu, Bin Hu, Zuozhong Xie, Hui Li, Hong Liu, Mao Ye, Xiang Chen, Jing Liu
J Immunother Cancer. 2022; 10(5): e003819. Published online 2022 May 16. doi: 10.1136/jitc-2021-003819
PMCID:
PMC9115032
AbstractArticlePDF–14M
7.
Regulation of MRE11A by UBQLN4 leads to cisplatin resistance in patients with esophageal squamous cell carcinoma
Tomohiro Murakami, Yoshiaki Shoji, Tomohiko Nishi, Shu‐Ching Chang, Ron D. Jachimowicz, Sojun Hoshimoto, Shigeshi Ono, Yosef Shiloh, Hiroya Takeuchi, Yuko Kitagawa, Dave S. B. Hoon, Matias A. Bustos
Mol Oncol. 2021 Apr; 15(4): 1069–1087. Published online 2021 Mar 8. doi: 10.1002/1878-0261.12929
PMCID:
PMC8024730
AbstractArticlePDF–2.7M
8.
UBQLN4 is an ATM substrate that stabilizes the anti‐apoptotic proteins BCL2A1 and BCL2L10 in mesothelioma
Fang Liu, RunSang Pan, HongYu Ding, LiLing Gu, Yun Yang, ChuanYin Li, YongJie Xu, Ronggui Hu, Hui Chen, XiangYan Zhang, YingJie Nie
Mol Oncol. 2021 Dec; 15(12): 3738–3752. Published online 2021 Aug 30. doi: 10.1002/1878-0261.13058
PMCID:
PMC8637560
AbstractArticlePDF–5.9M
9.
The UbL-UBA Ubiquilin4 protein functions as a tumor suppressor in gastric cancer by p53-dependent and p53-independent regulation of p21
Shengkai Huang, Yan Li, Xinghua Yuan, Mei Zhao, Jia Wang, You Li, Yuan Li, Hong Lin, Qiao Zhang, Wenjie Wang, Dongdong Li, Xin Dong, Lanfen Li, Min Liu, Weiyan Huang, Changzhi Huang
Cell Death Differ. 2019 Mar; 26(3): 516–530. Published online 2018 Jun 13. doi: 10.1038/s41418-018-0141-4
PMCID:
PMC6370890
AbstractArticlePDF–3.4M
10.
UBQLN4 recognizes mislocalized transmembrane domain proteins and targets these to proteasomal degradation
Rigel Suzuki, Hiroyuki Kawahara
EMBO Rep. 2016 Jun; 17(6): 842–857. Published online 2016 Apr 22. doi: 10.15252/embr.201541402
PMCID:
PMC5278606
AbstractArticlePDF–2.6M
11.
Candidate genes investigation for severe nonalcoholic fatty liver disease based on bioinformatics analysis
Shan Qi, Changhong Wang, Chunfu Li, Pu Wang, Minghui Liu
Medicine (Baltimore) 2017 Aug; 96(32): e7743. Published online 2017 Aug 11. doi: 10.1097/MD.0000000000007743
PMCID:
PMC5556226
AbstractArticlePDF–1.5M
12.
Degradation of gap junction connexins is regulated by the interaction with Cx43-interacting protein of 75 kDa (CIP75)
Jennifer L. Kopanic, Barbara Schlingmann, Michael Koval, Alan F. Lau, Paul L. Sorgen, Vivian F. Su
Biochem J. Author manuscript; available in PMC 2016 Mar 15.
Published in final edited form as: Biochem J. 2015 Mar 15; 466(3): 571–585. doi: 10.1042/BJ20141042
PMCID:
PMC4783143
AbstractArticlePDF–1.4M
13.
Ubiquitin-independent Proteasomal Degradation of Endoplasmic Reticulum-localized Connexin43 Mediated by CIP75
Vivian Su, Reid Nakagawa, Michael Koval, Alan F. Lau
J Biol Chem. 2010 Dec 24; 285(52): 40979–40990. Published online 2010 Oct 12. doi: 10.1074/jbc.M110.170753
PMCID:
PMC3003397
AbstractArticlePDF–3.4M
14.
Structure of hRpn10 bound to UBQLN2 UBL illustrates basis for complementarity between shuttle factors and substrates at the proteasome
Xiang Chen, Danielle L Ebelle, Brandon J Wright, Vinidhra Sridharan, Evan Hooper, Kylie J Walters
J Mol Biol. Author manuscript; available in PMC 2020 Mar 1.
Published in final edited form as: J Mol Biol. 2019 Mar 1; 431(5): 939–955. Published online 2019 Jan 18. doi: 10.1016/j.jmb.2019.01.021
PMCID:
PMC6389388
AbstractArticlePDF–2.7M
15.
The deubiquitinating enzyme USP2a regulates the p53 pathway by targeting Mdm2
Lauren F Stevenson, Alison Sparks, Nerea Allende-Vega, Dimitris P Xirodimas, David P Lane, Mark K Saville
EMBO J. 2007 Feb 21; 26(4): 976–986. Published online 2007 Feb 8. doi: 10.1038/sj.emboj.7601567
PMCID:
PMC1852834
AbstractArticlePDF–467K
16.
Ubiquilin4 is an adaptor protein that recruits Ubiquilin1 to the autophagy machinery
Dong Yun Lee, David Arnott, Eric J Brown
EMBO Rep. 2013 Apr; 14(4): 373–381. Published online 2013 Mar 5. doi: 10.1038/embor.2013.22
PMCID:
PMC3615663
AbstractArticlePDF–1.2M
17.
A Novel Connexin43-interacting Protein, CIP75, Which Belongs to the UbL-UBA Protein Family, Regulates the Turnover of Connexin43
Xinli Li, Vivian Su, Wendy E. Kurata, Chengshi Jin, Alan F. Lau
J Biol Chem. Author manuscript; available in PMC 2010 May 27.
Published in final edited form as: J Biol Chem. 2008 Feb 29; 283(9): 5748–5759. Published online 2007 Dec 13. doi: 10.1074/jbc.M709288200
PMCID:
PMC2877505
AbstractArticlePDF–3.3M
18.
RTL8 promotes nuclear localization of UBQLN2 to subnuclear compartments associated with protein quality control
Harihar Milaganur Mohan, Hanna Trzeciakiewicz, Amit Pithadia, Emily V. Crowley, Regina Pacitto, Nathaniel Safren, Bryce Trotter, Chengxin Zhang, Xiaogen Zhou, Yang Zhang, Venkatesha Basrur, Henry L. Paulson, Lisa M. Sharkey
Cell Mol Life Sci. 2022 Mar; 79(3): 176. Published online 2022 Mar 5. doi: 10.1007/s00018-022-04170-z
PMCID:
PMC9376861
AbstractArticlePDF–6.1M
19.
Enzymatic analysis of WWP2 E3 ubiquitin ligase using protein microarrays identifies autophagy-related substrates
Hanjie Jiang, Claire Y. Chiang, Zan Chen, Sara Nathan, Gabriel D’Agostino, Joao A. Paulo, Guang Song, Heng Zhu, Sandra B. Gabelli, Philip A. Cole
J Biol Chem. 2022 May; 298(5): 101854. Published online 2022 Mar 21. doi: 10.1016/j.jbc.2022.101854
PMCID:
PMC9034101
AbstractArticlePDF–3.7M
20.
Nuclear export of ubiquitinated proteins via the UBIN-POST system
Shoshiro Hirayama, Munechika Sugihara, Daisuke Morito, Shun-ichiro Iemura, Tohru Natsume, Shigeo Murata, Kazuhiro Nagata
Proc Natl Acad Sci U S A. 2018 May 1; 115(18): E4199–E4208. Published online 2018 Apr 16. doi: 10.1073/pnas.1711017115
PMCID:
PMC5939056
AbstractArticlePDF–1.8M

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