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Items: 1 to 20 of 45

1.
High core 1β1,3-galactosyltransferase 1 expression is associated with poor prognosis and promotes cellular radioresistance in lung adenocarcinoma
Yong Chen, Yanyan Ji, Lin Shen, Ying Li, Yue Ren, Hongcan Shi, Yue Li, Yunjiang Wu
J Cancer Res Clin Oncol. 2024; 150(4): 214. Published online 2024 Apr 25. doi: 10.1007/s00432-024-05745-y
PMCID:
PMC11045595
AbstractArticlePDF–4.9M
2.
Dysregulation and prometastatic function of glycosyltransferase C1GALT1 modulated by cHP1BP3/ miR-1-3p axis in bladder cancer
Zengqi Tan, Yazhuo Jiang, Liang Liang, Jinpeng Wu, Lin Cao, Xiaoman Zhou, Zhihui Song, Zhenyu Ye, Ziyan Zhao, Hui Feng, Zewen Dong, Shuai Lin, Zhangjian Zhou, Yili Wang, Xiang Li, Feng Guan
J Exp Clin Cancer Res. 2022; 41: 228. Published online 2022 Jul 21. doi: 10.1186/s13046-022-02438-7
PMCID:
PMC9306173
AbstractArticlePDF–16M
3.
Elevated miR‐124‐3p in the aging colon disrupts mucus barrier and increases susceptibility to colitis by targeting T‐synthase
Li Huang, Ting‐yi Sun, Liang‐jun Hu, Shi‐long Hu, Hai‐mei Sun, Fu‐qian Zhao, Bo Wu, Shu Yang, Feng‐qing Ji, De‐shan Zhou
Aging Cell. 2020 Nov; 19(11): e13252. Published online 2020 Oct 11. doi: 10.1111/acel.13252
PMCID:
PMC7681053
AbstractArticlePDF–3.1M
4.
C1GALT1 predicts poor prognosis and is a potential therapeutic target in head and neck cancer
Mei-Chun Lin, Pin-Hui Chien, Hsin-Yi Wu, Syue-Ting Chen, Hsueh-Fen Juan, Pei-Jen Lou, Min-Chuan Huang
Oncogene. 2018; 37(43): 5780–5793. Published online 2018 Jun 21. doi: 10.1038/s41388-018-0375-0
PMCID:
PMC6202324
AbstractArticlePDF–1.7M
5.
T-Synthase Deficiency Enhances Oncogenic Features in Human Colorectal Cancer Cells via Activation of Epithelial-Mesenchymal Transition
Xichen Dong, Yuliang Jiang, Jian Liu, Zhe Liu, Tianbo Gao, Guangyu An, Tao Wen
Biomed Res Int. 2018; 2018: 9532389. Published online 2018 Jun 21. doi: 10.1155/2018/9532389
PMCID:
PMC6032660
AbstractArticlePDF–1.7M
6.
Galactosylation of IgA1 Is Associated with Common Variation in C1GALT1
Daniel P. Gale, Karen Molyneux, David Wimbury, Patricia Higgins, Adam P. Levine, Ben Caplin, Anna Ferlin, Peiran Yin, Christopher P. Nelson, Horia Stanescu, Nilesh J. Samani, Robert Kleta, Xueqing Yu, Jonathan Barratt
J Am Soc Nephrol. 2017 Jul; 28(7): 2158–2166. Published online 2017 Feb 16. doi: 10.1681/ASN.2016091043
PMCID:
PMC5491291
AbstractArticle
7.
Suppression of Core 1 Gal-Transferase Is Associated with Reduction of TF and Reciprocal Increase of Tn, sialyl-Tn and Core 3 Glycans in Human Colon Cancer Cells
Hannah Barrow, Benjamin Tam, Carrie A. Duckworth, Jonathan M. Rhodes, Lu-Gang Yu
PLoS One. 2013; 8(3): e59792. Published online 2013 Mar 25. doi: 10.1371/journal.pone.0059792
PMCID:
PMC3607565
AbstractArticlePDF–634K
8.
Targeted Disruption of Core 1 β1,3-galactosyltransferase (C1galt1) Induces Apical Endocytic Trafficking in Human Corneal Keratinocytes
Ana Guzman-Aranguez, Ashley M. Woodward, Jesús Pintor, Pablo Argüeso
PLoS One. 2012; 7(5): e36628. Published online 2012 May 4. doi: 10.1371/journal.pone.0036628
PMCID:
PMC3344913
AbstractArticlePDF–2.3M
9.
Systematic determination of the peptide acceptor preferences for the human UDP-Gal:glycoprotein-α-GalNAc β3 galactosyltranferase (T-synthase)
Cynthia Perrine, Tongzhong Ju, Richard D Cummings, Thomas A Gerken
Glycobiology. 2009 Mar; 19(3): 321–328. Published online 2008 Dec 10. doi: 10.1093/glycob/cwn143
PMCID:
PMC2733779
AbstractArticlePDF–339K
10.
Truncation of GalNAc-type O-glycans Suppresses CD44-mediated Osteoclastogenesis and Bone Metastasis in Breast Cancer
Neng-Yu Lin, Jian-Jr Lee, Syue-Ting Chen, Jung-An Lin, Chia-Hsuan Lin, Hsuan-Yu Lin, Yong-Han Su, Cheng-Chang Chen, Mei-Chun Lin, Ching-Ying Kuo, Min-Chuan Huang
Mol Cancer Res. 2023 Jul 5; 21(7): 664–674. Published online 2023 Apr 11. doi: 10.1158/1541-7786.MCR-22-0907
PMCID:
PMC10320474
AbstractArticlePDF–15M
11.
Interaction between GALNT12 and C1GALT1 Associates with Galactose-Deficient IgA1 and IgA Nephropathy
Yan-Na Wang, Xu-Jie Zhou, Pei Chen, Gui-Zhen Yu, Xue Zhang, Ping Hou, Li-Jun Liu, Su-Fang Shi, Ji-Cheng Lv, Hong Zhang
J Am Soc Nephrol. 2021 Mar; 32(3): 545–552. Published online 2021 Feb 16. doi: 10.1681/ASN.2020060823
PMCID:
PMC7920185
AbstractArticle
12.
C1GALT1 high expression is associated with poor survival of patients with pancreatic ductal adenocarcinoma and promotes cell invasiveness through integrin αv
Ting-Chun Kuo, Ming-Hsun Wu, Shih-Hung Yang, Syue-Ting Chen, Tzu-Wen Hsu, Jie-Yang Jhuang, Ying-Yu Liao, Yu-Wen Tien, Min-Chuan Huang
Oncogene. 2021; 40(7): 1242–1254. Published online 2021 Jan 8. doi: 10.1038/s41388-020-01594-4
PMCID:
PMC7892338
AbstractArticlePDF–4.4M
13.
A CRISPR Screen Using Subtilase Cytotoxin Identifies SLC39A9 as a Glycan-Regulating Factor
Toshiyuki Yamaji, Hisatoshi Hanamatsu, Tsuyoshi Sekizuka, Makoto Kuroda, Norimasa Iwasaki, Makoto Ohnishi, Jun-ichi Furukawa, Kinnosuke Yahiro, Kentaro Hanada
iScience. 2019 May 31; 15: 407–420. Published online 2019 May 8. doi: 10.1016/j.isci.2019.05.005
PMCID:
PMC6526310
AbstractArticlePDF–11M
14.
Microbial, metabolomic, and immunologic dynamics in a relapsing genetic mouse model of colitis induced by T-synthase deficiency
Jonathan P. Jacobs, Lin Lin, Maryam Goudarzi, Paul Ruegger, Dermot P. B. McGovern, Albert J. Fornace, Jr, James Borneman, Lijun Xia, Jonathan Braun
Gut Microbes. 2017; 8(1): 1–16. Published online 2016 Nov 22. doi: 10.1080/19490976.2016.1257469
PMCID:
PMC5341916
AbstractArticlePDF–1.7M
15.
GWAS for serum galactose-deficient IgA1 implicates critical genes of the O-glycosylation pathway
Krzysztof Kiryluk, Yifu Li, Zina Moldoveanu, Hitoshi Suzuki, Colin Reily, Ping Hou, Jingyuan Xie, Nikol Mladkova, Sindhuri Prakash, Clara Fischman, Samantha Shapiro, Robert A. LeDesma, Drew Bradbury, Iuliana Ionita-Laza, Frank Eitner, Thomas Rauen, Nicolas Maillard, Francois Berthoux, Jürgen Floege, Nan Chen, Hong Zhang, Francesco Scolari, Robert J. Wyatt, Bruce A. Julian, Ali G. Gharavi, Jan Novak
PLoS Genet. 2017 Feb; 13(2): e1006609. Published online 2017 Feb 10. doi: 10.1371/journal.pgen.1006609
PMCID:
PMC5328405
AbstractArticlePDF–2.6M
16.
Promoters of Human Cosmc and T-synthase Genes Are Similar in Structure, Yet Different in Epigenetic Regulation
Junwei Zeng, Rongjuan Mi, Yingchun Wang, Yujing Li, Li Lin, Bing Yao, Lina Song, Irma van Die, Arlene B. Chapman, Richard D. Cummings, Peng Jin, Tongzhong Ju
J Biol Chem. 2015 Jul 31; 290(31): 19018–19033. Published online 2015 Jun 10. doi: 10.1074/jbc.M115.654244
PMCID:
PMC4521027
AbstractArticlePDF–2.9M
17.
Up-regulation of C1GALT1 promotes breast cancer cell growth through MUC1-C signaling pathway
Chih-Hsing Chou, Miao-Juei Huang, Chi-Hau Chen, Ming-Kwang Shyu, John Huang, Ji-Shiang Hung, Chiun-Sheng Huang, Min-Chuan Huang
Oncotarget. 2015 Mar 20; 6(8): 6123–6135. Published online 2015 Jan 27. doi: 10.18632/oncotarget.3045
PMCID:
PMC4467426
AbstractArticlePDF–2.4M
18.
C1GALT1 overexpression promotes the invasive behavior of colon cancer cells through modifying O-glycosylation of FGFR2
Ji-Shiang Hung, John Huang, Yo-Chuen Lin, Miao-Juei Huang, Po-Huang Lee, Hong-Shiee Lai, Jin-Tung Liang, Min-Chuan Huang
Oncotarget. 2014 Apr 30; 5(8): 2096–2106. Published online 2014 Mar 15. doi: 10.18632/oncotarget.1815
PMCID:
PMC4039148
AbstractArticlePDF–4.9M
19.
Cytokines Alter IgA1 O-Glycosylation by Dysregulating C1GalT1 and ST6GalNAc-II Enzymes
Hitoshi Suzuki, Milan Raska, Koshi Yamada, Zina Moldoveanu, Bruce A. Julian, Robert J. Wyatt, Yasuhiko Tomino, Ali G. Gharavi, Jan Novak
J Biol Chem. 2014 Feb 21; 289(8): 5330–5339. Published online 2013 Jan 7. doi: 10.1074/jbc.M113.512277
PMCID:
PMC3931088
AbstractArticlePDF–1.4M
20.
Glycosyltransferase-specific Golgi-targeting Mechanisms
Armen Petrosyan, Mohamed F. Ali, Pi-Wan Cheng
J Biol Chem. 2012 Nov 2; 287(45): 37621–37627. Published online 2012 Sep 17. doi: 10.1074/jbc.C112.403006
PMCID:
PMC3488040
AbstractArticlePDF–1.8M

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