PMC Links for Gene (Select 56925) - PMC

Select item 64357111.

The putative tumour suppressor protein Latexin is secreted by prostate luminal cells and is downregulated in malignancy

Robert I. Seed, Alberto J. Taurozzi, Daniel J. Wilcock, Giovanna Nappo, Holger H. H. Erb, Martin L. Read, Mark Gurney, Leanne K. Archer, Saburo Ito, Martin G. Rumsby, John L. Petrie, Aled Clayton, Norman J. Maitland, Anne T. Collins

Sci Rep. 2019; 9: 5120. Published online 2019 Mar 26. doi: 10.1038/s41598-019-41379-8

PMCID:: PMC6435711

Abstract Article PDF–2.8M

Select item 53805532.

Bone Microenvironment Changes in Latexin Expression Promote Chemoresistance

Mi Zhang, Mary Osisami, Jinlu Dai, Jill M. Keller, June Escara-Wilke, Atsushi Mizokami, Evan T. Keller

Mol Cancer Res. Author manuscript; available in PMC 2018 Apr 1.

Published in final edited form as: Mol Cancer Res. 2017 Apr; 15(4): 457–466. Published online 2017 Jan 13. doi: 10.1158/1541-7786.MCR-16-0392

PMCID:: PMC5380553

Abstract Article PDF–657K

Select item 36831033.

The Hematopoietic Stem Cell Regulatory Gene Latexin has Tumor Suppressive Properties in Malignant Melanoma

Viswanathan Muthusamy, Sanjay Premi, Cara Soper, James Platt, Marcus Bosenberg

J Invest Dermatol. Author manuscript; available in PMC 2014 Jan 1.

Published in final edited form as: J Invest Dermatol. 2013 Jul; 133(7): 1827–1833. Published online 2013 Jan 30. doi: 10.1038/jid.2013.48

PMCID:: PMC3683103

Abstract Article PDF–1.1M

Select item 30803454.

Latexin expression is downregulated in human gastric carcinomas and exhibits tumor suppressor potential

Yong Li, Zhuoma Basang, Huirong Ding, Zheming Lu, Tao Ning, Haoran Wei, Hong Cai, Yang Ke

BMC Cancer. 2011; 11: 121. Published online 2011 Apr 6. doi: 10.1186/1471-2407-11-121

PMCID:: PMC3080345

Abstract Article PDF–2.1M

Select item 100319645.

Circ_0002715 promotes the development of osteoarthritis through regulating LXN by sponging miR-127-5p

Hongbo Liu, Hongxia Zhao, Yin Huang, Ming Lei

J Orthop Surg Res. 2023; 18: 230. Published online 2023 Mar 22. doi: 10.1186/s13018-023-03638-3

PMCID:: PMC10031964

Abstract Article PDF–4.4M

Select item 46996186.

Latexin exhibits tumor-suppressor potential in pancreatic ductal adenocarcinoma

ZHANXIONG XUE, YUHUI ZHOU, CHENG WANG, JIHANG ZHENG, PU ZHANG, LINGLING ZHOU, LIANG WU, YUNFENG SHAN, MENGSI YE, YUN HE, ZHENZHAI CAI

Oncol Rep. 2016 Jan; 35(1): 50–58. Published online 2015 Oct 27. doi: 10.3892/or.2015.4353

PMCID:: PMC4699618

Abstract Article PDF–906K

Select item 43961647.

Latexin inhibits the proliferation of CD133+ miapaca-2 pancreatic cancer stem-like cells

Zhan-Xiong Xue, Ji-Hang Zheng, Zhi-Qiang Zheng, Jing-Li Cai, Xiao-Hua Ye, Cheng Wang, Wei-Jian Sun, Xiang Zhou, Ming-Dong Lu, Pi-Hong Li, Zhen-Zhai Cai

World J Surg Oncol. 2014; 12: 404. Published online 2014 Dec 30. doi: 10.1186/1477-7819-12-404

PMCID:: PMC4396164

Abstract Article PDF–1.8M

Select item 34599658.

Latexin Is Down-Regulated in Hematopoietic Malignancies and Restoration of Expression Inhibits Lymphoma Growth

Yi Liu, Dianna Howard, Kyle Rector, Carol Swiderski, Jason Brandon, Lawrence Schook, Jayesh Mehta, J. Scott Bryson, Subbarao Bondada, Ying Liang

PLoS One. 2012; 7(9): e44979. Published online 2012 Sep 27. doi: 10.1371/journal.pone.0044979

PMCID:: PMC3459965

Abstract Article PDF–747K

Select item 5548269.

Structure of human carboxypeptidase A4 with its endogenous protein inhibitor, latexin

Irantzu Pallarès, Roman Bonet, Raquel García-Castellanos, Salvador Ventura, Francesc X. Avilés, Josep Vendrell, F. Xavier Gomis-Rüth

Proc Natl Acad Sci U S A. 2005 Mar 15; 102(11): 3978–3983. Published online 2005 Feb 28. doi: 10.1073/pnas.0500678102

PMCID:: PMC554826

Abstract Article PDF–952K

Select item 729995810.

Latexin deficiency in mice up-regulates inflammation and aggravates colitis through HECTD1/Rps3/NF-κB pathway

Yaping Li, Baohua Huang, Hua Yang, Shuang Kan, Yanling Yao, Xin Liu, Shiming Pu, Guozhang He, Taj-Malook Khan, Guangying Qi, Zuping Zhou, Wei Shu, Ming Chen

Sci Rep. 2020; 10: 9868. Published online 2020 Jun 17. doi: 10.1038/s41598-020-66789-x

PMCID:: PMC7299958

Abstract Article PDF–2.7M

Select item 596587211.

Alterations in the brain interactome of the intrinsically disordered N-terminal domain of the cellular prion protein (PrP^C) in Alzheimer’s disease

Sarah Ulbrich, Petra Janning, Ralf Seidel, Jakob Matschke, Anika Gonsberg, Sebastian Jung, Markus Glatzel, Martin Engelhard, Konstanze F. Winklhofer, Jörg Tatzelt

PLoS One. 2018; 13(5): e0197659. Published online 2018 May 23. doi: 10.1371/journal.pone.0197659

PMCID:: PMC5965872

Abstract Article PDF–2.4M

Select item 184794812.

Large-scale mapping of human protein–protein interactions by mass spectrometry

Rob M Ewing, Peter Chu, Fred Elisma, Hongyan Li, Paul Taylor, Shane Climie, Linda McBroom-Cerajewski, Mark D Robinson, Liam O'Connor, Michael Li, Rod Taylor, Moyez Dharsee, Yuen Ho, Adrian Heilbut, Lynda Moore, Shudong Zhang, Olga Ornatsky, Yury V Bukhman, Martin Ethier, Yinglun Sheng, Julian Vasilescu, Mohamed Abu-Farha, Jean-Philippe Lambert, Henry S Duewel, Ian I Stewart, Bonnie Kuehl, Kelly Hogue, Karen Colwill, Katharine Gladwish, Brenda Muskat, Robert Kinach, Sally-Lin Adams, Michael F Moran, Gregg B Morin, Thodoros Topaloglou, Daniel Figeys

Mol Syst Biol. 2007; 3: 89. Published online 2007 Mar 13. doi: 10.1038/msb4100134

PMCID:: PMC1847948

Abstract Article PDF–440K

Select item 629516513.

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression

Lei Yu, Natee Jearawiriyapaisarn, Mary P. Lee, Tomonori Hosoya, Qingqing Wu, Greggory Myers, Kim-Chew Lim, Ryo Kurita, Yukio Nakamura, Anne B. Vojtek, Jean-François Rual, James Douglas Engel

Genes Dev. 2018 Dec 1; 32(23-24): 1537–1549. doi: 10.1101/gad.318436.118

PMCID:: PMC6295165

Abstract Article PDF–3.5M

Select item 464794114.

hORFeome v3.1: A resource of human open reading frames representing over 10,000 human genes

Philippe Lamesch, Ning Li, Stuart Milstein, Changyu Fan, Tong Hao, Gabor Szabo, Zhenjun Hu, Kavitha Venkatesan, Graeme Bethel, Paul Martin, Jane Rogers, Stephanie Lawlor, Stuart McLaren, Amélie Dricot, Heather Borick, Michael E. Cusick, Jean Vandenhaute, Ian Dunham, David E. Hill, Marc Vidal

Genomics. 2007 Mar; 89(3): 307–315. doi: 10.1016/j.ygeno.2006.11.012

PMCID:: PMC4647941

Abstract Article

Select item 347780415.

A Census of Human Soluble Protein Complexes

Pierre C. Havugimana, G. Traver Hart, Tamás Nepusz, Haixuan Yang, Andrei L. Turinsky, Zhihua Li, Peggy I. Wang, Daniel R. Boutz, Vincent Fong, Sadhna Phanse, Mohan Babu, Stephanie A. Craig, Pingzhao Hu, Cuihong Wan, James Vlasblom, Vaqaarun-Nisa Dar, Alexander Bezginov, Gregory W. Clark, Gabriel C. Wu, Shoshana J. Wodak, Elisabeth R.M. Tillier, Alberto Paccanaro, Edward M. Marcotte, Andrew Emili

Cell. Author manuscript; available in PMC 2013 Aug 31.

Published in final edited form as: Cell. 2012 Aug 31; 150(5): 1068–1081. doi: 10.1016/j.cell.2012.08.011

PMCID:: PMC3477804

Abstract Article PDF–7.7M

Select item 426658816.

A proteome-scale map of the human interactome network

Thomas Rolland, Murat Taşan, Benoit Charloteaux, Samuel J. Pevzner, Quan Zhong, Nidhi Sahni, Song Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan D. Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Braun, Marc Brehme, Martin P. Broly, Anne-Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe-Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash A. Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean-Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-László Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal

Cell. Author manuscript; available in PMC 2015 Nov 20.

Published in final edited form as: Cell. 2014 Nov 20; 159(5): 1212–1226. doi: 10.1016/j.cell.2014.10.050

PMCID:: PMC4266588

Abstract Article PDF–3.1M

Select item 716998317.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x