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Select item 106718431.

Cancer Associated PRDM9: Implications for Linking Genomic Instability and Meiotic Recombination

Paris Ladias, Georgios S. Markopoulos, Charilaos Kostoulas, Ioanna Bouba, Sofia Markoula, Ioannis Georgiou

Int J Mol Sci. 2023 Nov; 24(22): 16522. Published online 2023 Nov 20. doi: 10.3390/ijms242216522

PMCID:: PMC10671843

Abstract Article PDF–3.3M

Select item 62116512.

Aberrant PRDM9 expression impacts the pan-cancer genomic landscape

Armande Ang Houle, Heather Gibling, Fabien C. Lamaze, Hilary A. Edgington, David Soave, Marie-Julie Fave, Mawusse Agbessi, Vanessa Bruat, Lincoln D. Stein, Philip Awadalla

Genome Res. 2018 Nov; 28(11): 1611–1620. doi: 10.1101/gr.231696.117

PMCID:: PMC6211651

Abstract Article PDF–4.9M

Select item 56250323.

Structural basis of human PR/SET domain 9 (PRDM9) allele C–specific recognition of its cognate DNA sequence

Anamika Patel, Xing Zhang, Robert M. Blumenthal, Xiaodong Cheng

J Biol Chem. 2017 Sep 29; 292(39): 15994–16002. Published online 2017 Aug 11. doi: 10.1074/jbc.M117.805754

PMCID:: PMC5625032

Abstract Article PDF–2.8M

Select item 52163774.

An exploratory study of predisposing genetic factors for DiGeorge/velocardiofacial syndrome

Laia Vergés, Francesca Vidal, Esther Geán, Alexandra Alemany-Schmidt, Maria Oliver-Bonet, Joan Blanco

Sci Rep. 2017; 7: 40031. Published online 2017 Jan 6. doi: 10.1038/srep40031

PMCID:: PMC5216377

Abstract Article PDF–1.1M

Select item 48395895.

X marks the spot: PRDM9 rescues hybrid sterility by finding hidden treasure in the genome

Maciej J. Zelazowski, Francesca Cole

Nat Struct Mol Biol. Author manuscript; available in PMC 2016 Oct 5.

Published in final edited form as: Nat Struct Mol Biol. 2016 Apr 5; 23(4): 267–269. doi: 10.1038/nsmb.3201

PMCID:: PMC4839589

Article PDF–455K

Select item 42307426.

The Red Queen Model of Recombination Hotspots Evolution in the Light of Archaic and Modern Human Genomes

Yann Lesecque, Sylvain Glémin, Nicolas Lartillot, Dominique Mouchiroud, Laurent Duret

PLoS Genet. 2014 Nov; 10(11): e1004790. Published online 2014 Nov 13. doi: 10.1371/journal.pgen.1004790

PMCID:: PMC4230742

Abstract Article PDF–1.9M

Select item 41105167.

Primate evolution of the recombination regulator PRDM9

Jerrod J. Schwartz, David J. Roach, James H. Thomas, Jay Shendure

Nat Commun. Author manuscript; available in PMC 2015 Jan 8.

Published in final edited form as: Nat Commun. 2014; 5: 4370. Published online 2014 Jul 8. doi: 10.1038/ncomms5370

PMCID:: PMC4110516

Abstract Article PDF–1.3M

Select item 35895318.

Rare allelic forms of PRDM9 associated with childhood leukemogenesis

Julie Hussin, Daniel Sinnett, Ferran Casals, Youssef Idaghdour, Vanessa Bruat, Virginie Saillour, Jasmine Healy, Jean-Christophe Grenier, Thibault de Malliard, Stephan Busche, Jean-François Spinella, Mathieu Larivière, Greg Gibson, Anna Andersson, Linda Holmfeldt, Jing Ma, Lei Wei, Jinghui Zhang, Gregor Andelfinger, James R. Downing, Charles G. Mullighan, Philip Awadalla

Genome Res. 2013 Mar; 23(3): 419–430. doi: 10.1101/gr.144188.112

PMCID:: PMC3589531

Abstract Article PDF–652K

Select item 35457729.

Recombination regulator PRDM9 influences the instability of its own coding sequence in humans

Alec J. Jeffreys, Victoria E. Cotton, Rita Neumann, Kwan-Wood Gabriel Lam

Proc Natl Acad Sci U S A. 2013 Jan 8; 110(2): 600–605. Published online 2012 Dec 24. doi: 10.1073/pnas.1220813110

PMCID:: PMC3545772

Abstract Article PDF–428K

Select item 323220810.

The Case of the Fickle Fingers: How the PRDM9 Zinc Finger Protein Specifies Meiotic Recombination Hotspots in Humans

Laure Ségurel, Ellen Miranda Leffler, Molly Przeworski

PLoS Biol. 2011 Dec; 9(12): e1001211. Published online 2011 Dec 6. doi: 10.1371/journal.pbio.1001211

PMCID:: PMC3232208

Abstract Article PDF–246K

Select item 279455011.

Extraordinary Molecular Evolution in the PRDM9 Fertility Gene

James H. Thomas, Ryan O. Emerson, Jay Shendure

PLoS One. 2009; 4(12): e8505. Published online 2009 Dec 30. doi: 10.1371/journal.pone.0008505

PMCID:: PMC2794550

Abstract Article PDF–1.6M

Select item 1078892112.

FBLN5 was Regulated by PRDM9, and Promoted Senescence and Osteogenic Differentiation of Human Periodontal Ligament Stem Cells

Mengyao Zhao, Rong Rong, Chen Zhang, Haoqing Yang, Xiao Han, Zhipeng Fan, Ying Zheng, Jianpeng Zhang

Curr Stem Cell Res Ther. 2023 Nov 29; 19(3): 417–425. Published online 2023 Nov 29. doi: 10.2174/1574888X18666230822100054

PMCID:: PMC10788921

Abstract Article PDF–4.9M

Select item 984345713.

Association of Single Nucleotide Polymorphisms in the PYGO2 and PRDM9 Genes with Idiopathic Azoospermia in Iranian Infertile Male Patients

Sanaz Soleymani Moud, Katayun Kamal Seraji, Mina Ramezani, Zeynab Piravar

Iran J Med Sci. 2023 Jan; 48(1): 77–84. doi: 10.30476/IJMS.2022.93009.2433

PMCID:: PMC9843457

Abstract Article PDF–392K

Select item 862975314.

Pathogenic variants of meiotic double strand break (DSB) formation genes PRDM9 and ANKRD31 in premature ovarian insufficiency

Yiyang Wang, Ting Guo, Hanni Ke, Qian Zhang, Shan Li, Wei Luo, Yingying Qin

Genet Med. 2021; 23(12): 2309–2315. Published online 2021 Jul 13. doi: 10.1038/s41436-021-01266-y

PMCID:: PMC8629753

Abstract Article PDF–1.7M

Select item 611692415.

PRDM9, a driver of the genetic map

Corinne Grey, Frédéric Baudat, Bernard de Massy

PLoS Genet. 2018 Aug; 14(8): e1007479. Published online 2018 Aug 30. doi: 10.1371/journal.pgen.1007479

PMCID:: PMC6116924

Abstract Article PDF–4.4M

Select item 587871316.

PRDM9 and its role in genetic recombination

Kenneth Paigen, Petko M. Petkov

Trends Genet. Author manuscript; available in PMC 2019 Apr 1.

Published in final edited form as: Trends Genet. 2018 Apr; 34(4): 291–300. Published online 2018 Jan 21. doi: 10.1016/j.tig.2017.12.017

PMCID:: PMC5878713

Abstract Article PDF–690K

Select item 570521917.

A map of human PRDM9 binding provides evidence for novel behaviors of PRDM9 and other zinc-finger proteins in meiosis

Nicolas Altemose, Nudrat Noor, Emmanuelle Bitoun, Afidalina Tumian, Michael Imbeault, J Ross Chapman, A Radu Aricescu, Simon R Myers

eLife. 2017; 6: e28383. Published online 2017 Oct 26. doi: 10.7554/eLife.28383

PMCID:: PMC5705219

Abstract Article PDF–4.8M

Select item 475643718.

Re-engineering the zinc fingers of PRDM9 reverses hybrid sterility in mice

Benjamin Davies, Edouard Hatton, Nicolas Altemose, Julie G. Hussin, Florencia Pratto, Gang Zhang, Anjali Gupta Hinch, Daniela Moralli, Daniel Biggs, Rebeca Diaz, Chris Preece, Ran Li, Emmanuelle Bitoun, Kevin Brick, Catherine M. Green, R. Daniel Camerini-Otero, Simon R. Myers, Peter Donnelly

Nature. Author manuscript; available in PMC 2016 Aug 11.

Published in final edited form as: Nature. 2016 Feb 11; 530(7589): 171–176. Published online 2016 Feb 3. doi: 10.1038/nature16931