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Select item 77189501.

PDSS2‐Del2, a new variant of PDSS2, promotes tumor cell metastasis and angiogenesis in hepatocellular carcinoma via activating NF‐κB

Tingting Zeng, Zhi Tang, Lili Liang, Daqin Suo, Lei Li, Jiangchao Li, Yunfei Yuan, Xin‐Yuan Guan, Yan Li

Mol Oncol. 2020 Dec; 14(12): 3184–3197. Published online 2020 Nov 4. doi: 10.1002/1878-0261.12826

PMCID:: PMC7718950

Abstract Article PDF–8.5M

Select item 49979592.

Non-additive genome-wide association scan reveals a new gene associated with habitual coffee consumption

Nicola Pirastu, Maarten Kooyman, Antonietta Robino, Ashley van der Spek, Luciano Navarini, Najaf Amin, Lennart C. Karssen, Cornelia M Van Duijn, Paolo Gasparini

Sci Rep. 2016; 6: 31590. Published online 2016 Aug 25. doi: 10.1038/srep31590

PMCID:: PMC4997959

Abstract Article PDF–438K

Select item 43569283.

Decaprenyl diphosphate synthase subunit 2 as a prognosis factor in hepatocellular carcinoma

Wei Huang, Fei Gao, Kang Li, Wen Wang, Ya-Rou Lai, Shao-Hui Tang, Dong-Hua Yang

World J Gastroenterol. 2015 Mar 14; 21(10): 3055–3065. Published online 2015 Mar 14. doi: 10.3748/wjg.v21.i10.3055

PMCID:: PMC4356928

Abstract Article PDF–2.4M

Select item 42090444.

Decreased expression of prenyl diphosphate synthase subunit 2 correlates with reduced survival of patients with gastric cancer

Mitsuro Kanda, Shuji Nomoto, Hisaharu Oya, Ryoji Hashimoto, Hideki Takami, Dai Shimizu, Fuminori Sonohara, Daisuke Kobayashi, Chie Tanaka, Suguru Yamada, Tsutomu Fujii, Goro Nakayama, Hiroyuki Sugimoto, Masahiko Koike, Kenta Murotani, Michitaka Fujiwara, Yasuhiro Kodera

J Exp Clin Cancer Res. 2014; 33(1): 88. Published online 2014 Oct 22. doi: 10.1186/s13046-014-0088-3

PMCID:: PMC4209044

Abstract Article PDF–1.6M

Select item 37987225.

Focal segmental glomerulosclerosis is associated with a PDSS2 haplotype and, independently, with a decreased content of coenzyme Q₁₀

David L. Gasser, Cheryl A. Winkler, Min Peng, Ping An, Louise M. McKenzie, Gregory D. Kirk, Yuchen Shi, Letian X. Xie, Beth N. Marbois, Catherine F. Clarke, Jeffrey B. Kopp

Am J Physiol Renal Physiol. 2013 Oct 15; 305(8): F1228–F1238. Published online 2013 Aug 7. doi: 10.1152/ajprenal.00143.2013

PMCID:: PMC3798722

Abstract Article

Select item 82745866.

PDSS2 Inhibits the Ferroptosis of Vascular Endothelial Cells in Atherosclerosis by Activating Nrf2

Kai Yang, Hejian Song, Delu Yin

J Cardiovasc Pharmacol. 2021 Jun; 77(6): 767–776. Published online 2021 Apr 29. doi: 10.1097/FJC.0000000000001030

PMCID:: PMC8274586

Abstract Article PDF–1.1M

Select item 69473127.

Sp1 Mediates the Constitutive Expression and Repression of the PDSS2 Gene in Lung Cancer Cells

Lanyue Hu, Quanmei Chen, Yitao Wang, Na Zhang, Peixin Meng, Tong Liu, Youquan Bu

Genes (Basel) 2019 Dec; 10(12): 977. Published online 2019 Nov 27. doi: 10.3390/genes10120977

PMCID:: PMC6947312

Abstract Article PDF–3.0M

Select item 31522258.

Genotype–Phenotype Correlations in Non-Finnish Congenital Nephrotic Syndrome

Eduardo Machuca, Geneviève Benoit, Fabien Nevo, Marie-Josèphe Tête, Olivier Gribouval, Audrey Pawtowski, Per Brandström, Chantal Loirat, Patrick Niaudet, Marie-Claire Gubler, Corinne Antignac

J Am Soc Nephrol. 2010 Jul; 21(7): 1209–1217. doi: 10.1681/ASN.2009121309

PMCID:: PMC3152225

Abstract Article

Select item 27349549.

Candidate Gene/Loci Studies in Cleft Lip/Palate and Dental Anomalies Finds Novel Susceptibility Genes for Clefts

Alexandre R. Vieira, Toby G. McHenry, Sandra Daack-Hirsch, Jeffrey C. Murray, Mary L. Marazita

Genet Med. Author manuscript; available in PMC 2009 Aug 30.

Published in final edited form as: Genet Med. 2008 Sep; 10(9): 668–674. doi: 10.1097/GIM.0b013e3181833793

PMCID:: PMC2734954

Abstract Article PDF–50K

Select item 1008090810.

The UAS thioredoxin-like domain of UBXN7 regulates E3 ubiquitin ligase activity of RNF111/Arkadia

Sadek Amhaz, Batiste Boëda, Mouna Chouchène, Sabrina Colasse, Florent Dingli, Damarys Loew, Julien Henri, Céline Prunier, Laurence Levy

BMC Biol. 2023; 21: 73. Published online 2023 Apr 7. doi: 10.1186/s12915-023-01576-4

PMCID:: PMC10080908

Abstract Article PDF–3.2M

Select item 356108411.

Loci Associated with N-Glycosylation of Human Immunoglobulin G Show Pleiotropy with Autoimmune Diseases and Haematological Cancers

Gordan Lauc, Jennifer E. Huffman, Maja Pučić, Lina Zgaga, Barbara Adamczyk, Ana Mužinić, Mislav Novokmet, Ozren Polašek, Olga Gornik, Jasminka Krištić, Toma Keser, Veronique Vitart, Blanca Scheijen, Hae-Won Uh, Mariam Molokhia, Alan Leslie Patrick, Paul McKeigue, Ivana Kolčić, Ivan Krešimir Lukić, Olivia Swann, Frank N. van Leeuwen, L. Renee Ruhaak, Jeanine J. Houwing-Duistermaat, P. Eline Slagboom, Marian Beekman, Anton J. M. de Craen, André M. Deelder, Qiang Zeng, Wei Wang, Nicholas D. Hastie, Ulf Gyllensten, James F. Wilson, Manfred Wuhrer, Alan F. Wright, Pauline M. Rudd, Caroline Hayward, Yurii Aulchenko, Harry Campbell, Igor Rudan

PLoS Genet. 2013 Jan; 9(1): e1003225. Published online 2013 Jan 31. doi: 10.1371/journal.pgen.1003225

PMCID:: PMC3561084

Abstract Article PDF–1.0M

Select item 642645512.

Mapping the genetic landscape of human cells

Max A. Horlbeck, Albert Xu, Min Wang, Neal K. Bennett, Chong Y. Park, Derek Bogdanoff, Britt Adamson, Eric D. Chow, Martin Kampmann, Tim R. Peterson, Ken Nakamura, Michael A. Fischbach, Jonathan S. Weissman, Luke A. Gilbert

Cell. Author manuscript; available in PMC 2019 Aug 9.

Published in final edited form as: Cell. 2018 Aug 9; 174(4): 953–967.e22. Published online 2018 Jul 19. doi: 10.1016/j.cell.2018.06.010

PMCID:: PMC6426455

Abstract Article PDF–3.6M

Select item 294347613.

Genetic Variants in Nuclear-Encoded Mitochondrial Genes Influence AIDS Progression

Sher L. Hendrickson, James A. Lautenberger, Leslie Wei Chinn, Michael Malasky, Efe Sezgin, Lawrence A. Kingsley, James J. Goedert, Gregory D. Kirk, Edward D. Gomperts, Susan P. Buchbinder, Jennifer L. Troyer, Stephen J. O'Brien

PLoS One. 2010; 5(9): e12862. Published online 2010 Sep 21. doi: 10.1371/journal.pone.0012862

PMCID:: PMC2943476

Abstract Article PDF–461K

Select item 268304714.

Ubiquitin-mediated proteolysis of HuR by heat shock

Kotb Abdelmohsen, Subramanya Srikantan, Xiaoling Yang, Ashish Lal, Hyeon Ho Kim, Yuki Kuwano, Stefanie Galban, Kevin G Becker, Davida Kamara, Rafael de Cabo, Myriam Gorospe

EMBO J. 2009 May 6; 28(9): 1271–1282. Published online 2009 Mar 26. doi: 10.1038/emboj.2009.67

PMCID:: PMC2683047

Abstract Article PDF–1.4M

Select item 319082615.

Interactions of Pathological Hallmark Proteins: TUBULIN POLYMERIZATION PROMOTING PROTEIN/p25, β-AMYLOID, AND α-SYNUCLEIN

Judit Oláh, Orsolya Vincze, Dezső Virók, Dóra Simon, Zsolt Bozsó, Natália Tőkési, István Horváth, Emma Hlavanda, János Kovács, Anna Magyar, Mária Szűcs, Ferenc Orosz, Botond Penke, Judit Ovádi

J Biol Chem. 2011 Sep 30; 286(39): 34088–34100. Published online 2011 Aug 8. doi: 10.1074/jbc.M111.243907

PMCID:: PMC3190826

Abstract Article PDF–5.7M

Select item 294516816.

Variation at the NFATC2 Locus Increases the Risk of Thiazolidinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study

Swneke D. Bailey, Changchun Xie, Ron Do, Alexandre Montpetit, Rafael Diaz, Viswanathan Mohan, Bernard Keavney, Salim Yusuf, Hertzel C. Gerstein, James C. Engert, Sonia Anand, on behalf of the DREAM investigators

Diabetes Care. 2010 Oct; 33(10): 2250–2253. Published online 2010 Jul 13. doi: 10.2337/dc10-0452

PMCID:: PMC2945168

Abstract Article PDF–153K

Select item 277583217.

Gene-centric Association Signals for Lipids and Apolipoproteins Identified via the HumanCVD BeadChip

Philippa J. Talmud, Fotios Drenos, Sonia Shah, Tina Shah, Jutta Palmen, Claudio Verzilli, Tom R. Gaunt, Jacky Pallas, Ruth Lovering, Kawah Li, Juan Pablo Casas, Reecha Sofat, Meena Kumari, Santiago Rodriguez, Toby Johnson, Stephen J. Newhouse, Anna Dominiczak, Nilesh J. Samani, Mark Caulfield, Peter Sever, Alice Stanton, Denis C. Shields, on behalf of the ASCOT investigators, Sandosh Padmanabhan, Olle Melander, Claire Hastie, Christian Delles, on behalf of the NORDIL investigators, Shah Ebrahim, Michael G. Marmot, George Davey Smith, Debbie A. Lawlor, Patricia B. Munroe, for the BRIGHT Consortium, Ian N. Day, Mika Kivimaki, John Whittaker, Steve E. Humphries, Aroon D. Hingorani

Am J Hum Genet. 2009 Nov 13; 85(5): 628–642. doi: 10.1016/j.ajhg.2009.10.014

PMCID:: PMC2775832

Abstract Article PDF–2.8M

Select item 461721118.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043

PMCID:: PMC4617211

Abstract Article PDF–2.2M

Select item 553161119.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 816503020.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

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PMC Links for Gene (Select 57107) (23)
PMC
PREDICTED: Homo sapiens decaprenyl diphosphate synthase subunit 2 (PDSS2), trans...
PREDICTED: Homo sapiens decaprenyl diphosphate synthase subunit 2 (PDSS2), transcript variant X4, mRNA
gi|2217362319|ref|XM_047419096.1|

Nucleotide
PREDICTED: Homo sapiens decaprenyl diphosphate synthase subunit 2 (PDSS2), trans...
PREDICTED: Homo sapiens decaprenyl diphosphate synthase subunit 2 (PDSS2), transcript variant X5, mRNA
gi|2217362321|ref|XM_017011082.3|

Nucleotide
all trans-polyprenyl-diphosphate synthase PDSS2 isoform X5 [Homo sapiens]
all trans-polyprenyl-diphosphate synthase PDSS2 isoform X5 [Homo sapiens]
gi|1034650925|ref|XP_016866571.1|

Protein

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