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Items: 1 to 20 of 127

1.
Non-canonical BAD activity regulates breast cancer cell and tumor growth via 14-3-3 binding and mitochondrial metabolism
Jasdeep Mann, John Maringa Githaka, Timothy W. Buckland, Ning Yang, Rachel Montpetit, Namrata Patel, Lei Li, Shairaz Baksh, Roseline Godbout, Hélène Lemieux, Ing Swie Goping
Oncogene. 2019; 38(18): 3325–3339. Published online 2019 Jan 11. doi: 10.1038/s41388-018-0673-6
PMCID:
PMC6756016
AbstractArticlePDF–3.8M
2.
Targeting BCL-xL improves the efficacy of bromodomain and extra-terminal protein inhibitors in triple-negative breast cancer by eliciting the death of senescent cells
Sylvia S. Gayle, Jennifer M. Sahni, Bryan M. Webb, Kristen L. Weber-Bonk, Melyssa S. Shively, Raffaella Spina, Eli E. Bar, Mathew K. Summers, Ruth A. Keri
J Biol Chem. 2019 Jan 18; 294(3): 875–886. Published online 2018 Nov 27. doi: 10.1074/jbc.RA118.004712
PMCID:
PMC6341404
AbstractArticlePDF–4.0M
3.
Association of Pro-apoptotic Bad Gene Expression Changes with Benign Thyroid Nodules
NURDAN GÜL, BERNA TEMEL, DURAN USTEK, SEMA SIRMA-EKMEKÇI, YERSU KAPRAN, FATIH TUNCA, YASEMIN GILES-ŞENYÜREK, UĞUR ÖZBEK, FARUK ALAGÖL
In Vivo. 2018 May-Jun; 32(3): 555–559. Published online 2018 May 3. doi: 10.21873/invivo.112275
PMCID:
PMC6000808
AbstractArticlePDF–88K
4.
Biphasic regulation of InsP3 receptor gating by dual Ca2+ release channel BH3-like domains mediates Bcl-xL control of cell viability
Jun Yang, Horia Vais, Wenen Gu, J. Kevin Foskett
Proc Natl Acad Sci U S A. 2016 Mar 29; 113(13): E1953–E1962. Published online 2016 Mar 14. doi: 10.1073/pnas.1517935113
PMCID:
PMC4822637
AbstractArticlePDF–2.3M
5.
Epstein-Barr Virus MicroRNA miR-BART20-5p Suppresses Lytic Induction by Inhibiting BAD-Mediated caspase-3-Dependent Apoptosis
Hyoji Kim, Hoyun Choi, Suk Kyeong Lee
J Virol. 2016 Feb 1; 90(3): 1359–1368. Prepublished online 2015 Nov 18. Published online 2016 Jan 15. doi: 10.1128/JVI.02794-15
PMCID:
PMC4719597
AbstractArticlePDF–1.7M
6.
The downregulation of Bcl-xL/Bcl-2-associated death promoter indicates worse outcomes in patients with small cell lung carcinoma
Yaoyang Yu, Zhaokui Zhong, Yaowu Guan
Int J Clin Exp Pathol. 2015; 8(10): 13075–13082. Published online 2015 Oct 1.
PMCID:
PMC4680448
AbstractArticlePDF–875K
7.
BAD-mediated apoptotic pathway is associated with human cancer development
XIAOMANG B STICKLES, DOUGLAS C MARCHION, ELONA BICAKU, ENTIDHAR AL SAWAH, FOROUGH ABBASI, YIN XIONG, NADIM BOU ZGHEIB, BERNADETTE M BOAC, BRIAN C ORR, PATRICIA L JUDSON, AMY BERRY, ARDESHIR HAKAM, ROBERT M WENHAM, SACHIN M APTE, ANDERS E BERGLUND, JOHNATHAN M LANCASTER
Int J Mol Med. 2015 Apr; 35(4): 1081–1087. Published online 2015 Feb 5. doi: 10.3892/ijmm.2015.2091
PMCID:
PMC4356438
AbstractArticlePDF–1024K
8.
RAS signaling promotes resistance to JAK inhibitors by suppressing BAD-mediated apoptosis
Peter S. Winter, Kristopher A. Sarosiek, Kevin H. Lin, Manja Meggendorfer, Susanne Schnittger, Anthony Letai, Kris C. Wood
Sci Signal. Author manuscript; available in PMC 2015 Jun 23.
Published in final edited form as: Sci Signal. 2014 Dec 23; 7(357): ra122. Published online 2014 Dec 23. doi: 10.1126/scisignal.2005301
PMCID:
PMC4353591
AbstractArticlePDF–1.9M
9.
BCL-2 family protein, BAD is down-regulated in breast cancer and inhibits cancer cell invasion
Maria Cekanova, Romaine I. Fernando, Nalin Siriwardhana, Mugdha Sukhthankar, Columba de la Parra, Jirayus Woraratphoka, Christine Malone, Anders Ström, Seung J. Baek, Paul A. Wade, Arnold M. Saxton, Robert M. Donnell, Richard G. Pestell, Suranganie Dharmawardhane, Jay Wimalasena
Exp Cell Res. Author manuscript; available in PMC 2016 Feb 1.
Published in final edited form as: Exp Cell Res. 2015 Feb 1; 331(1): 1–10. Published online 2014 Dec 9. doi: 10.1016/j.yexcr.2014.11.016
PMCID:
PMC4304679
AbstractArticlePDF–1.3M
10.
Targeting proapoptotic protein BAD inhibits survival and self-renewal of cancer stem cells
K S R Sastry, M A Al-Muftah, Pu Li, M K Al-Kowari, E Wang, A Ismail Chouchane, D Kizhakayil, G Kulik, F M Marincola, A Haoudi, L Chouchane
Cell Death Differ. 2014 Dec; 21(12): 1936–1949. Published online 2014 Sep 12. doi: 10.1038/cdd.2014.140
PMCID:
PMC4227153
AbstractArticlePDF–5.9M
11.
Influenza Virus Induces Apoptosis via BAD-Mediated Mitochondrial Dysregulation
Anh T. Tran, John P. Cortens, Qiujiang Du, John A. Wilkins, Kevin M. Coombs
J Virol. 2013 Jan; 87(2): 1049–1060. doi: 10.1128/JVI.02017-12
PMCID:
PMC3554053
AbstractArticlePDF–3.0M
12.
Overexpression of Bcl-2–Associated Death Inhibits A549 Cell Growth In Vitro and In Vivo
Na Huang, Jing Zhu, Dan Liu, Ya-Lun Li, Bo-Jiang Chen, Yan-Qi He, Kun Liu, Xian-Ming Mo, Wei-Min Li
Cancer Biother Radiopharm. 2012 Mar; 27(2): 164–168. doi: 10.1089/cbr.2011.1018
PMCID:
PMC3304250
AbstractArticlePDF–280K
13.
Rapamycin Induces Bad Phosphorylation in Association with Its Resistance to Human Lung Cancer Cells
Yan Liu, Shi-Yong Sun, Taofeek K. Owonikoko, Gabriel L. Sica, Walter J. Curran, Fadlo R. Khuri, Xingming Deng
Mol Cancer Ther. Author manuscript; available in PMC 2013 Jan 1.
Published in final edited form as: Mol Cancer Ther. 2012 Jan; 11(1): 45–56. Published online 2011 Nov 4. doi: 10.1158/1535-7163.MCT-11-0578
PMCID:
PMC3256262
AbstractArticlePDF–2.0M
14.
BAD phosphorylation determines ovarian cancer chemo-sensitivity and patient survival
Douglas C. Marchion, Hope M. Cottrill, Yin Xiong, Ning Chen, Elona Bicaku, William J. Fulp, Nisha Bansal, Hye Sook Chon, Xiaomang B. Stickles, Siddharth G. Kamath, Ardeshir Hakam, Lihua Li, Dan Su, Carolina Moreno, Patricia L. Judson, Andrew Berchuck, Robert M. Wenham, Sachin M. Apte, Jesus Gonzalez-Bosquet, Gregory C. Bloom, Steven A. Eschrich, Said Sebti, Dung-Tsa Chen, Johnathan M. Lancaster
Clin Cancer Res. Author manuscript; available in PMC 2012 Oct 1.
Published in final edited form as: Clin Cancer Res. 2011 Oct 1; 17(19): 6356–6366. Published online 2011 Aug 17. doi: 10.1158/1078-0432.CCR-11-0735
PMCID:
PMC3186862
AbstractArticlePDF–3.5M
15.
Lysophosphatidic acid prevents apoptosis of Caco-2 colon cancer cells via activation of mitogen-activated protein kinase and phosphorylation of Bad
Raluca Rusovici, Amr Ghaleb, Hyunsuk Shim, Vincent W. Yang, C. Chris Yun
Biochim Biophys Acta. Author manuscript; available in PMC 2008 Aug 1.
Published in final edited form as: Biochim Biophys Acta. 2007 Aug; 1770(8): 1194–1203. Published online 2007 May 3. doi: 10.1016/j.bbagen.2007.04.008
PMCID:
PMC1989128
AbstractArticlePDF–513K
16.
Recruitment of BAD by the Chlamydia trachomatis Vacuole Correlates with Host-Cell Survival
Philippe Verbeke, Lynn Welter-Stahl, Songmin Ying, Jon Hansen, Georg Häcker, Toni Darville, David M Ojcius
PLoS Pathog. 2006 May; 2(5): e45. Published online 2006 May 19. doi: 10.1371/journal.ppat.0020045
PMCID:
PMC1463014
AbstractArticlePDF–518K
17.
MicroRNA-377 Downregulates Bcl-xL and Increases Apoptosis in Hepatocellular Carcinoma Cells
Hongyan Ge, Di Zou, Yingshu Wang, Hao Jiang, Liping Wang
Oncol Res. 2017; 25(1): 29–34. Published online 2017 Jan 2. doi: 10.3727/096504016X14719078133168
PMCID:
PMC7840731
AbstractArticlePDF–8.8M
18.
Targeting Rho GTPase effector p21 activated kinase 4 (PAK4) suppresses p-Bad-microRNA drug resistance axis leading to inhibition of pancreatic ductal adenocarcinoma proliferation
Ramzi M. Mohammad, Yiwei Li, Irfana Muqbil, Amro Aboukameel, William Senapedis, Erkan Baloglu, Yosef Landesman, Philip A. Philip, Asfar S. Azmi
Small GTPases. 2019 Sep; 10(5): 367–377. Published online 2017 Jun 23. doi: 10.1080/21541248.2017.1329694
PMCID:
PMC6748371
AbstractArticlePDF–1.2M
19.
High PGAM5 expression induces chemoresistance by enhancing Bcl-xL-mediated anti-apoptotic signaling and predicts poor prognosis in hepatocellular carcinoma patients
Jingjing Cheng, Dong Qian, Xiaofeng Ding, Tianqiang Song, Muyan Cai, Dan Xie, Yuwen Wang, Jinlin Zhao, Zhuang Liu, Zhiqiang Wu, Qingsong Pang, Li Zhu, Ping Wang, Xishan Hao, Zhiyong Yuan
Cell Death Dis. 2018 Oct; 9(10): 991. Published online 2018 Sep 24. doi: 10.1038/s41419-018-1017-8
PMCID:
PMC6155280
AbstractArticlePDF–3.0M
20.
Cytoprotective effect of neuropeptides on cancer stem cells: vasoactive intestinal peptide-induced antiapoptotic signaling
Konduru S Sastry, Aouatef Ismail Chouchane, Ena Wang, George Kulik, Francesco M Marincola, Lotfi Chouchane
Cell Death Dis. 2017 Jun; 8(6): e2844. Published online 2017 Jun 1. doi: 10.1038/cddis.2017.226
PMCID:
PMC5520887
AbstractArticlePDF–7.1M

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