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Items: 1 to 20 of 90

1.
A novel genetic variant in PTGS1 affects N-glycosylation of cyclooxygenase-1 causing a dominant–negative effect
Verónica Palma-Barqueros, Marilena Crescente, María Eugenia de la Morena, Melissa V Chan, Elena Almarza, Nuria Revilla, Natalia Bohdan, Antonia Miñano, José Padilla, Harriet E Allan, Tania Maffucci, Matthew L. Edin, Darryl. C. Zeldin, Cristina Mesa-Nuñez, Carlos Damian, Ana Marín-Quilez, Rocío Benito, Irene Martínez-Martínez, Nuria Bermejo, Ignacio Casas-Aviles, Agustín Rodríguez Alen, José Ramón González-Porras, Jesús María Hernández-Rivas, Vicente Vicente, Javier Corral, María Luisa Lozano, Timothy D. Warner, José María Bastida, José Rivera
Am J Hematol. Author manuscript; available in PMC 2024 Mar 14.
Published in final edited form as: Am J Hematol. 2021 Mar 1; 96(3): E83–E88. Published online 2021 Jan 5. doi: 10.1002/ajh.26076
PMCID:
PMC10938055
ArticlePDF–671K
2.
Association between Vitamin Intake and Chronic Kidney Disease According to a Variant Located Upstream of the PTGS1 Gene: A Cross-Sectional Analysis of Shika Study
Kim-Oanh Pham, Akinori Hara, Hiromasa Tsujiguchi, Keita Suzuki, Fumihiko Suzuki, Sakae Miyagi, Takayuki Kannon, Takehiro Sato, Kazuyoshi Hosomichi, Hirohito Tsuboi, Thao Thi Thu Nguyen, Yukari Shimizu, Yasuhiro Kambayashi, Masaharu Nakamura, Chie Takazawa, Haruki Nakamura, Toshio Hamagishi, Aki Shibata, Tadashi Konoshita, Atsushi Tajima, Hiroyuki Nakamura
Nutrients. 2022 May; 14(10): 2082. Published online 2022 May 16. doi: 10.3390/nu14102082
PMCID:
PMC9143472
AbstractArticlePDF–893K
3.
Identification of a homozygous recessive variant in PTGS1 resulting in a congenital aspirin-like defect in platelet function
Melissa V. Chan, Melissa A. Hayman, Suthesh Sivapalaratnam, Marilena Crescente, Harriet E. Allan, Matthew L. Edin, Darryl C. Zeldin, Ginger L. Milne, Jonathan Stephens, Daniel Greene, Moghees Hanif, Valerie B. O’Donnell, Liang Dong, Michael G. Malkowski, Claire Lentaigne, Katherine Wedderburn, Matthew Stubbs, Kate Downes, Willem H. Ouwehand, Ernest Turro, Daniel P. Hart, Kathleen Freson, Michael A. Laffan, Timothy D. Warner
Haematologica. 2021 May 1; 106(5): 1423–1432. Published online 2020 Apr 16. doi: 10.3324/haematol.2019.235895
PMCID:
PMC8094108
AbstractArticlePDF–1.3M
4.
Activated Platelets Induce Endothelial Cell Inflammatory Response in Psoriasis via COX-1
Michael S. Garshick, Michael Tawil, Tessa J. Barrett, Charissa M. Salud-Gnilo, Michael Eppler, Angela Lee, Jose U. Scher, Andrea L. Neimann, Sanja Jelic, Nehal N. Mehta, Edward A. Fisher, James G. Krueger, Jeffrey S. Berger
Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2021 May 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2020 May; 40(5): 1340–1351. Published online 2020 Mar 5. doi: 10.1161/ATVBAHA.119.314008
PMCID:
PMC7180109
AbstractArticlePDF–1.7M
5.
Epithelial Cells Induce a Cyclo-Oxygenase-1–Dependent Endogenous Reduction in Airway Smooth Muscle Contractile Phenotype
Michael J. O’Sullivan, Elizabeth Gabriel, Alice Panariti, Chan Y. Park, Gijs Ijpma, Jeffrey J. Fredberg, Anne-Marie Lauzon, James G. Martin
Am J Respir Cell Mol Biol. 2017 Dec; 57(6): 683–691. doi: 10.1165/rcmb.2016-0427OC
PMCID:
PMC5765417
AbstractArticlePDF–860K
6.
Colonic Saturated Fatty Acid Concentrations and Expression of COX-1, but not Diet, Predict Prostaglandin E2 in Normal Human Colon Tissue
ElKhansa Sidahmed, Ananda Sen, Jianwei Ren, Arsh Patel, D. Kim Turgeon, Mack T. Ruffin, Dean Brenner, Zora Djuric
Nutr Cancer. Author manuscript; available in PMC 2017 Oct 1.
Published in final edited form as: Nutr Cancer. 2016 Oct; 68(7): 1192–1201. Published online 2016 Aug 22. doi: 10.1080/01635581.2016.1213866
PMCID:
PMC5061293
AbstractArticlePDF–682K
7.
Human Platelets Utilize Cycloxygenase-1 to Generate Dioxolane A3, a Neutrophil-activating Eicosanoid
Christine Hinz, Maceler Aldrovandi, Charis Uhlson, Lawrence J. Marnett, Hilary J. Longhurst, Timothy D. Warner, Saydul Alam, David A. Slatter, Sarah N. Lauder, Keith Allen-Redpath, Peter W. Collins, Robert C. Murphy, Christopher P. Thomas, Valerie B. O'Donnell
J Biol Chem. 2016 Jun 24; 291(26): 13448–13464. Published online 2016 Apr 22. doi: 10.1074/jbc.M115.700609
PMCID:
PMC4919433
AbstractArticlePDF–3.4M
8.
Aberrant over-expression of COX-1 intersects multiple pro-tumorigenic pathways in high-grade serous ovarian cancer
Andrew J. Wilson, Oluwole Fadare, Alicia Beeghly-Fadiel, Deok-Soo Son, Qi Liu, Shilin Zhao, Jeanette Saskowski, Md. Jashim Uddin, Cristina Daniel, Brenda Crews, Brian D. Lehmann, Jennifer A. Pietenpol, Marta A. Crispens, Lawrence J. Marnett, Dineo Khabele
Oncotarget. 2015 Aug 28; 6(25): 21353–21368. Published online 2015 May 4. doi: 10.18632/oncotarget.3860
PMCID:
PMC4673270
AbstractArticlePDF–3.7M
9.
Fatty acids and TxA2 generation, in the absence of platelet-COX-1 activity
A.P. DeFilippis, S.N. Rai, A. Cambon, R.J. Miles, A.S. Jaffe, A.B. Moser, R.O. Jones, R. Bolli, S.P. Schulman
Nutr Metab Cardiovasc Dis. Author manuscript; available in PMC 2015 Apr 24.
Published in final edited form as: Nutr Metab Cardiovasc Dis. 2014 Apr; 24(4): 428–433. Published online 2013 Oct 23. doi: 10.1016/j.numecd.2013.08.012
PMCID:
PMC4409424
AbstractArticlePDF–181K
10.
Cyclooxygenase-1 as the Main Source of Proinflammatory Factors After Sodium Orthovanadate Treatment
Jan Korbecki, Irena Baranowska-Bosiacka, Izabela Gutowska, Katarzyna Piotrowska, Dariusz Chlubek
Biol Trace Elem Res. 2015; 163(1): 103–111. Published online 2014 Nov 15. doi: 10.1007/s12011-014-0176-4
PMCID:
PMC4297299
AbstractArticlePDF–1.7M
11.
Impact of Blood Type, Functional Polymorphism (T-1676C) of the COX-1 Gene Promoter and Clinical Factors on the Development of Peptic Ulcer during Cardiovascular Prophylaxis with Low-Dose Aspirin
Pin-Yao Wang, Hsiu-Ping Chen, Angela Chen, Feng-Woei Tsay, Kwok-Hung Lai, Sung-Shuo Kao, Wen-Chi Chen, Chao-Hung Kuo, Nan-Jing Peng, Hui-Hwa Tseng, Ping-I Hsu
Biomed Res Int. 2014; 2014: 616018. Published online 2014 Aug 27. doi: 10.1155/2014/616018
PMCID:
PMC4163467
AbstractArticlePDF–512K
12.
Suboptimal inhibition of platelet cyclo-oxygenase-1 (COX-1) by aspirin in lupus erythematosus: Association with metabolic syndrome
Vivian K. Kawai, Ingrid Avalos, Annette Oeser, John A. Oates, Ginger L. Milne, Joseph F. Solus, Cecilia P. Chung, C. Michael Stein
Arthritis Care Res (Hoboken) Author manuscript; available in PMC 2015 Feb 1.
Published in final edited form as: Arthritis Care Res (Hoboken). 2014 Feb; 66(2): 285–292. doi: 10.1002/acr.22169
PMCID:
PMC3946810
AbstractArticlePDF–269K
13.
Identification and functional characterization of polymorphisms in human cyclooxygenase-1 (PTGS1)
Craig R. Lee, Frank G. Bottone, Jr, Joseph M. Krahn, Leping Li, Harvey W. Mohrenweiser, Molly E. Cook, Robert M. Petrovich, Douglas A. Bell, Thomas E. Eling, Darryl C. Zeldin
Pharmacogenet Genomics. Author manuscript; available in PMC 2007 Oct 24.
Published in final edited form as: Pharmacogenet Genomics. 2007 Feb; 17(2): 145–160. doi: 10.1097/01.fpc.0000236340.87540.e3
PMCID:
PMC2041861
AbstractArticlePDF–1.2M
14.
Characterization of a novel transcript of prostaglandin endoperoxide H synthase 1 with a tissue-specific profile of expression.
M H Plant, O Laneuville
Biochem J. 1999 Dec 15; 344(Pt 3): 677–685.
PMCID:
PMC1220689
SummaryPDF–296K
15.
Human cyclo-oxygenase-1 and an alternative splice variant: contrasts in expression of mRNA, protein and catalytic activities
Claus Schneider, William E. Boeglin, Alan R. Brash
Biochem J. 2005 Jan 1; 385(Pt 1): 57–64. Prepublished online 2004 Sep 13. Published online 2004 Dec 14. doi: 10.1042/BJ20041115
PMCID:
PMC1134673
AbstractArticlePDF–598K
16.
Human mtRF1 terminates COX1 translation and its ablation induces mitochondrial ribosome-associated quality control
Franziska Nadler, Elena Lavdovskaia, Angelique Krempler, Luis Daniel Cruz-Zaragoza, Sven Dennerlein, Ricarda Richter-Dennerlein
Nat Commun. 2022; 13: 6406. Published online 2022 Oct 27. doi: 10.1038/s41467-022-34088-w
PMCID:
PMC9613700
AbstractArticlePDF–1.9M
17.
MYLK and PTGS1 Genetic Variations Associated with Osteoporosis and Benign Breast Tumors in Korean Women
Hye-Won Cho, Hyun-Seok Jin, Yong-Bin Eom
Genes (Basel) 2021 Mar; 12(3): 378. Published online 2021 Mar 6. doi: 10.3390/genes12030378
PMCID:
PMC7998336
AbstractArticlePDF–1.0M
18.
Cyclooxygenase enzyme and PGE2 expression in patients with functional and non-functional pituitary adenomas
Nasrin Akbari, Mohammad Ghorbani, Vahid Salimi, Alimohammad Alimohammadi, Mohammad E. Khamseh, Hamideh Akbari, Mitra Nourbakhsh, Alireza Sheikhi, S. Fahimeh Taghavi, Masoumeh Tavakoli-Yaraki
BMC Endocr Disord. 2020; 20: 39. Published online 2020 Mar 14. doi: 10.1186/s12902-020-0515-8
PMCID:
PMC7071656
AbstractArticlePDF–1.3M
19.
Interaction between COX-1 and COX-2 increases susceptibility to ischemic stroke in a Chinese population
Lei Zhao, Jinghuan Fang, Muke Zhou, Jie Zhou, Lihua Yu, Ning Chen, Li He
BMC Neurol. 2019; 19: 291. Published online 2019 Nov 17. doi: 10.1186/s12883-019-1505-1
PMCID:
PMC6859610
AbstractArticlePDF–569K
20.
Inhibition of PTGS1 promotes osteogenic differentiation of adipose-derived stem cells by suppressing NF-kB signaling
Yuejun Wang, Yunsong Liu, Min Zhang, Longwei Lv, Xiao Zhang, Ping Zhang, Yongsheng Zhou
Stem Cell Res Ther. 2019; 10: 57. Published online 2019 Feb 13. doi: 10.1186/s13287-019-1167-3
PMCID:
PMC6375160
AbstractArticlePDF–4.0M

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