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Items: 20

1.
Folliculin-interacting protein FNIP2 impacts on overweight and obesity through a polymorphism in a conserved 3′ untranslated region
Lara P. Fernández, Nerea Deleyto-Seldas, Gonzalo Colmenarejo, Alba Sanz, Sonia Wagner, Ana Belén Plata-Gómez, Mónica Gómez-Patiño, Susana Molina, Isabel Espinosa-Salinas, Elena Aguilar-Aguilar, Sagrario Ortega, Osvaldo Graña-Castro, Viviana Loria-Kohen, Pablo J. Fernández-Marcos, Alejo Efeyan, Ana Ramírez de Molina
Genome Biol. 2022; 23: 230. Published online 2022 Oct 31. doi: 10.1186/s13059-022-02798-5
PMCID:
PMC9620695
AbstractArticlePDF–1.4M
2.
Loss of FLCN-FNIP1/2 induces a non-canonical interferon response in human renal tubular epithelial cells
Iris E Glykofridis, Jaco C Knol, Jesper A Balk, Denise Westland, Thang V Pham, Sander R Piersma, Sinéad M Lougheed, Sepide Derakhshan, Puck Veen, Martin A Rooimans, Saskia E van Mil, Franziska Böttger, Pino J Poddighe, Irma van de Beek, Jarno Drost, Fried JT Zwartkruis, Renee X de Menezes, Hanne EJ Meijers-Heijboer, Arjan C Houweling, Connie R Jimenez, Rob MF Wolthuis
eLife. 2021; 10: e61630. Published online 2021 Jan 18. doi: 10.7554/eLife.61630
PMCID:
PMC7899648
AbstractArticlePDF–3.4M
3.
Nutrient-induced FNIP degradation by SCFβ-TRCP regulates FLCN complex localization and promotes renal cancer progression
Katsuyuki Nagashima, Hidefumi Fukushima, Kouhei Shimizu, Aya Yamada, Masumi Hidaka, Hisashi Hasumi, Tetsuro Ikebe, Satoshi Fukumoto, Koji Okabe, Hiroyuki Inuzuka
Oncotarget. 2017 Feb 7; 8(6): 9947–9960. Published online 2016 Dec 25. doi: 10.18632/oncotarget.14221
PMCID:
PMC5354783
AbstractArticlePDF–5.5M
4.
Folliculin variants linked to Birt-Hogg-Dubé syndrome are targeted for proteasomal degradation
Lene Clausen, Amelie Stein, Martin Grønbæk-Thygesen, Lasse Nygaard, Cecilie L. Søltoft, Sofie V. Nielsen, Michael Lisby, Tommer Ravid, Kresten Lindorff-Larsen, Rasmus Hartmann-Petersen
PLoS Genet. 2020 Nov; 16(11): e1009187. Published online 2020 Nov 2. doi: 10.1371/journal.pgen.1009187
PMCID:
PMC7660926
AbstractArticlePDF–3.9M
5.
Direct regulation of FNIP1 and FNIP2 by MEF2 sustains MTORC1 activation and tumor progression in pancreatic cancer
Li Xia, Tiejian Nie, Fangfang Lu, Lu Huang, Xiaolong Shi, Dongni Ren, Jianjun Lu, Xiaobin Li, Tuo Xu, Bozhou Cui, Qing Wang, Guodong Gao, Qian Yang
Autophagy. 2024; 20(3): 505–524. Published online 2023 Sep 29. doi: 10.1080/15548627.2023.2259735
PMCID:
PMC10936626
AbstractArticlePDF–4.8M
6.
Identification and characterization of a novel folliculin-interacting protein FNIP2
Hisashi Hasumi, Masaya Baba, Seung-Beom Hong, Yukiko Hasumi, Ying Huang, Masahiro Yao, Vladimir A. Valera, W. Marston Linehan, Laura S. Schmidt
Gene. Author manuscript; available in PMC 2009 Aug 17.
Published in final edited form as: Gene. 2008 May 31; 415(1-2): 60–67. Published online 2008 Mar 4. doi: 10.1016/j.gene.2008.02.022
PMCID:
PMC2727720
AbstractArticlePDF–1.9M
7.
Structural basis for FLCN RagC GAP activation in MiT-TFE substrate-selective mTORC1 regulation
Rachel M. Jansen, Roberta Peruzzo, Simon A. Fromm, Adam L. Yokom, Roberto Zoncu, James H. Hurley
Sci Adv. 2022 Sep; 8(37): eadd2926. Published online 2022 Sep 14. doi: 10.1126/sciadv.add2926
PMCID:
PMC9473554
AbstractArticlePDF–3.2M
8.
Inactivation of the FLCN Tumor Suppressor Gene Induces TFE3 Transcriptional Activity by Increasing Its Nuclear Localization
Seung-Beom Hong, HyoungBin Oh, Vladimir A. Valera, Masaya Baba, Laura S. Schmidt, W. Marston Linehan
PLoS One. 2010; 5(12): e15793. Published online 2010 Dec 29. doi: 10.1371/journal.pone.0015793
PMCID:
PMC3012117
AbstractArticlePDF–3.7M
9.
FLCN, a novel autophagy component, interacts with GABARAP and is regulated by ULK1 phosphorylation
Elaine A Dunlop, Sara Seifan, Tijs Claessens, Christian Behrends, Miriam AF Kamps, Ewelina Rozycka, Alain J Kemp, Ravi K Nookala, John Blenis, Barry J Coull, James T Murray, Maurice AM van Steensel, Simon Wilkinson, Andrew R Tee
Autophagy. 2014 Oct 1; 10(10): 1749–1760. Published online 2014 Jul 22. doi: 10.4161/auto.29640
PMCID:
PMC4198360
AbstractArticlePDF–5.2M
10.
The FNIP co-chaperones decelerate the Hsp90 chaperone cycle and enhance drug binding
Mark R. Woodford, Diana M. Dunn, Adam R. Blanden, Dante Capriotti, David Loiselle, Chrisostomos Prodromou, Barry Panaretou, Philip F. Hughes, Aaron Smith, Wendi Ackerman, Timothy A. Haystead, Stewart N. Loh, Dimitra Bourboulia, Laura S. Schmidt, W. Marston Linehan, Gennady Bratslavsky, Mehdi Mollapour
Nat Commun. 2016; 7: 12037. Published online 2016 Jun 29. doi: 10.1038/ncomms12037
PMCID:
PMC4931344
AbstractArticlePDF–5.6M
11.
Negative regulation of EGFR signalling by the human folliculin tumour suppressor protein
Laura A. Laviolette, Julien Mermoud, Isabel A. Calvo, Nicholas Olson, Myriam Boukhali, Ortrud K. Steinlein, Elisabeth Roider, Elke C. Sattler, Dachuan Huang, Bin Tean Teh, Mo Motamedi, Wilhelm Haas, Othon Iliopoulos
Nat Commun. 2017; 8: 15866. Published online 2017 Jun 28. doi: 10.1038/ncomms15866
PMCID:
PMC5493755
AbstractArticlePDF–2.4M
12.
Combinatorial CRISPR screen identifies fitness effects of gene paralogues
Nicola A. Thompson, Marco Ranzani, Louise van der Weyden, Vivek Iyer, Victoria Offord, Alastair Droop, Fiona Behan, Emanuel Gonçalves, Anneliese Speak, Francesco Iorio, James Hewinson, Victoria Harle, Holly Robertson, Elizabeth Anderson, Beiyuan Fu, Fengtang Yang, Guido Zagnoli-Vieira, Phil Chapman, Martin Del Castillo Velasco-Herrera, Mathew J. Garnett, Stephen P. Jackson, David J. Adams
Nat Commun. 2021; 12: 1302. Published online 2021 Feb 26. doi: 10.1038/s41467-021-21478-9
PMCID:
PMC7910459
AbstractArticlePDF–3.3M
13.
C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy
Bing-Ru Yan, Taoyingnan Li, Etienne Coyaud, Estelle M. N. Laurent, Jonathan St-Germain, Yuhuan Zhou, Peter K. Kim, Brian Raught, John H. Brumell
Autophagy. 2022; 18(4): 829–840. Published online 2021 Aug 25. doi: 10.1080/15548627.2021.1960116
PMCID:
PMC9037554
AbstractArticlePDF–4.1M
14.
Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy
Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang
Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003
PMCID:
PMC8897022
AbstractArticlePDF–3.0M
15.
VIRMA mediates preferential m6A mRNA methylation in 3′UTR and near stop codon and associates with alternative polyadenylation
Yanan Yue, Jun Liu, Xiaolong Cui, Jie Cao, Guanzheng Luo, Zezhou Zhang, Tao Cheng, Minsong Gao, Xiao Shu, Honghui Ma, Fengqin Wang, Xinxia Wang, Bin Shen, Yizhen Wang, Xinhua Feng, Chuan He, Jianzhao Liu
Cell Discov. 2018; 4: 10. Published online 2018 Feb 27. doi: 10.1038/s41421-018-0019-0
PMCID:
PMC5826926
AbstractArticlePDF–2.3M
16.
Personalized Smoking Cessation: Interactions between Nicotine Dose, Dependence and Quit-Success Genotype Score
Jed E Rose, Frédérique M Behm, Tomas Drgon, Catherine Johnson, George R Uhl
Mol Med. 2010 Jul-Aug; 16(7-8): 247–253. Published online 2010 Mar 17. doi: 10.2119/molmed.2009.00159
Correction in:
Mol Med. 2012; 18(1): 729.
PMCID:
PMC2896464
AbstractArticlePDF–2.4M
17.
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery
Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili
Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z
PMCID:
PMC9279285
AbstractArticlePDF–2.5M
18.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
19.
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences
Mammalian Gene Collection (MGC) Program Team
Proc Natl Acad Sci U S A. 2002 Dec 24; 99(26): 16899–16903. Published online 2002 Dec 11. doi: 10.1073/pnas.242603899
PMCID:
PMC139241
AbstractArticlePDF–118K
20.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M

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