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Select item 72611701.

Structural and functional insights into CWC27/CWC22 heterodimer linking the exon junction complex to spliceosomes

Virginia Busetto, Isabelle Barbosa, Jérôme Basquin, Émelie Marquenet, Rémi Hocq, Magali Hennion, Janio Antonio Paternina, Abdelkader Namane, Elena Conti, Olivier Bensaude, Hervé Le Hir

Nucleic Acids Res. 2020 Jun 4; 48(10): 5670–5683. Published online 2020 Apr 24. doi: 10.1093/nar/gkaa267

PMCID:: PMC7261170

Abstract Article PDF–3.3M

Select item 38450972.

Crystal structure of the human eIF4AIII–CWC22 complex shows how a DEAD-box protein is inhibited by a MIF4G domain

Gretel Buchwald, Steffen Schüssler, Claire Basquin, Hervé Le Hir, Elena Conti

Proc Natl Acad Sci U S A. 2013 Nov 26; 110(48): E4611–E4618. Published online 2013 Nov 11. doi: 10.1073/pnas.1314684110

PMCID:: PMC3845097

Abstract Article PDF–2.3M

Select item 35356183.

Human spliceosomal protein CWC22 plays a role in coupling splicing to exon junction complex deposition and nonsense-mediated decay

Andrei Alexandrov, David Colognori, Mei-Di Shu, Joan A. Steitz

Proc Natl Acad Sci U S A. 2012 Dec 26; 109(52): 21313–21318. Published online 2012 Dec 10. doi: 10.1073/pnas.1219725110

PMCID:: PMC3535618

Abstract Article PDF–1.0M

Select item 71893854.

Gene expression network analysis of lymph node involvement in colon cancer identifies AHSA2, CDK10, and CWC22 as possible prognostic markers

Sung Won Han, Ji Young Ahn, Soobin Lee, Young Seon Noh, Hee Chan Jung, Min Hyung Lee, Hae Jun Park, Hoon Jai Chun, Seong Ji Choi, Eun Sun Kim, Ji-Yun Lee

Sci Rep. 2020; 10: 7170. Published online 2020 Apr 28. doi: 10.1038/s41598-020-63806-x

PMCID:: PMC7189385

Abstract Article PDF–2.5M

Select item 12079375.

Distinct Requirements for Somatic and Germline Expression of a Generally Expressed Caernorhabditis Elegans Gene

W. G. Kelly, S. Xu, M. K. Montgomery, A. Fire

Genetics. 1997 May; 146(1): 227–238. doi: 10.1093/genetics/146.1.227

PMCID:: PMC1207937

Summary PDF–6.6M

Select item 58357736.

Structure of the human activated spliceosome in three conformational states

Xiaofeng Zhang, Chuangye Yan, Xiechao Zhan, Lijia Li, Jianlin Lei, Yigong Shi

Cell Res. 2018 Mar; 28(3): 307–322. Published online 2018 Jan 23. doi: 10.1038/cr.2018.14

PMCID:: PMC5835773

Abstract Article PDF–5.3M

Select item 32918637.

A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants

Sha Tao, Zhong Wang, Junjie Feng, Fang-Chi Hsu, Guangfu Jin, Seong-Tae Kim, Zheng Zhang, Henrik Gronberg, Lilly S. Zheng, William B. Isaacs, Jianfeng Xu, Jielin Sun

Carcinogenesis. 2012 Mar; 33(3): 598–603. Published online 2012 Jan 4. doi: 10.1093/carcin/bgr316

PMCID:: PMC3291863

Abstract Article PDF–109K

Select item 74381128.

NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency

Joana G Marques, Berkley E Gryder, Blaz Pavlovic, Yeonjoo Chung, Quy A Ngo, Fabian Frommelt, Matthias Gstaiger, Young Song, Katharina Benischke, Dominik Laubscher, Marco Wachtel, Javed Khan, Beat W Schäfer

eLife. 2020; 9: e54993. Published online 2020 Aug 3. doi: 10.7554/eLife.54993

PMCID:: PMC7438112

Abstract Article PDF–4.5M

Select item 34283249.

Targeted Ubiquitination and Degradation of G-Protein-Coupled Receptor Kinase 5 by the DDB1-CUL4 Ubiquitin Ligase Complex

Ziyan Wu, Yuejun Chen, Tong Yang, Qinqin Gao, Man Yuan, Lan Ma

PLoS One. 2012; 7(8): e43997. Published online 2012 Aug 27. doi: 10.1371/journal.pone.0043997

PMCID:: PMC3428324

Abstract Article PDF–2.0M

Select item 137026610.

Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis.

Melissa S Jurica, Lawrence J Licklider, Steven R Gygi, Nikolaus Grigorieff, Melissa J Moore

RNA. 2002 Apr; 8(4): 426–439. doi: 10.1017/s1355838202021088

PMCID:: PMC1370266

Summary PDF–11M

Select item 352217311.

The Cellular EJC Interactome Reveals Higher Order mRNP Structure and an EJC-SR Protein Nexus

Guramrit Singh, Alper Kucukural, Can Cenik, John D. Leszyk, Scott A. Shaffer, Zhiping Weng, Melissa J. Moore

Cell. Author manuscript; available in PMC 2013 May 9.

Published in final edited form as: Cell. 2012 Nov 9; 151(4): 750–764. Published online 2012 Oct 18. doi: 10.1016/j.cell.2012.10.007

PMCID:: PMC3522173

Abstract Article PDF–4.2M

Select item 381740412.

A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities

Franco J Vizeacoumar, Roland Arnold, Frederick S Vizeacoumar, Megha Chandrashekhar, Alla Buzina, Jordan T F Young, Julian H M Kwan, Azin Sayad, Patricia Mero, Steffen Lawo, Hiromasa Tanaka, Kevin R Brown, Anastasia Baryshnikova, Anthony B Mak, Yaroslav Fedyshyn, Yadong Wang, Glauber C Brito, Dahlia Kasimer, Taras Makhnevych, Troy Ketela, Alessandro Datti, Mohan Babu, Andrew Emili, Laurence Pelletier, Jeff Wrana, Zev Wainberg, Philip M Kim, Robert Rottapel, Catherine A O’Brien, Brenda Andrews, Charles Boone, Jason Moffat

Mol Syst Biol. 2013; 9: 696. Published online 2013 Oct 8. doi: 10.1038/msb.2013.54

PMCID:: PMC3817404

Abstract Article PDF–13M

Select item 603987013.

LuTHy: a double‐readout bioluminescence‐based two‐hybrid technology for quantitative mapping of protein–protein interactions in mammalian cells

Philipp Trepte, Sabrina Kruse, Simona Kostova, Sheila Hoffmann, Alexander Buntru, Anne Tempelmeier, Christopher Secker, Lisa Diez, Aline Schulz, Konrad Klockmeier, Martina Zenkner, Sabrina Golusik, Kirstin Rau, Sigrid Schnoegl, Craig C Garner, Erich E Wanker

Mol Syst Biol. 2018 Jul; 14(7): e8071. Published online 2018 Jul 11. doi: 10.15252/msb.20178071

PMCID:: PMC6039870

Abstract Article PDF–2.1M

Select item 660120814.

SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18

Manal Alsulami, Nayla Munawar, Eugene Dillon, Giorgio Oliviero, Kieran Wynne, Mona Alsolami, Catherine Moss, Peadar Ó Gaora, Fergal O'Meara, David Cotter, Gerard Cagney

Mol Cell Proteomics. 2019 Jul; 18(7): 1428–1436. Published online 2019 May 10. doi: 10.1074/mcp.RA119.001518

PMCID:: PMC6601208

Abstract Article PDF–1.8M

Select item 631799415.

SNIP1 Recruits TET2 to Regulate c-MYC Target Genes and Cellular DNA Damage Response

Lei-Lei Chen, Huai-Peng Lin, Wen-Jie Zhou, Chen-Xi He, Zhi-Yong Zhang, Zhou-Li Cheng, Jun-Bin Song, Peng Liu, Xin-Yu Chen, Yu-Kun Xia, Xiu-Fei Chen, Ren-Qiang Sun, Jing-Ye Zhang, Yi-Ping Sun, Lei Song, Bing-Jie Liu, Rui-Kai Du, Chen Ding, Fei Lan, Sheng-Lin Huang, Feng Zhou, Suling Liu, Yue Xiong, Dan Ye, Kun-Liang Guan

Cell Rep. Author manuscript; available in PMC 2019 Jan 3.

Published in final edited form as: Cell Rep. 2018 Nov 6; 25(6): 1485–1500.e4. doi: 10.1016/j.celrep.2018.10.028

PMCID:: PMC6317994

Abstract Article PDF–1.4M

Select item 953348616.

Circular RNA circPVT1 promotes nasopharyngeal carcinoma metastasis via the β-TrCP/c-Myc/SRSF1 positive feedback loop

Yongzhen Mo, Yumin Wang, Yian Wang, Xiangying Deng, Qijia Yan, Chunmei Fan, Shuai Zhang, Shanshan Zhang, Zhaojian Gong, Lei Shi, Qianjin Liao, Can Guo, Yong Li, Guiyuan Li, Zhaoyang Zeng, Weihong Jiang, Wei Xiong, Bo Xiang

Mol Cancer. 2022; 21: 192. Published online 2022 Oct 5. doi: 10.1186/s12943-022-01659-w