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Select item 53423041.

Hepatitis C virus infection inhibits a Src-kinase regulatory phosphatase and reduces T cell activation in vivo

Nirjal Bhattarai, James H. McLinden, Jinhua Xiang, M. Meleah Mathahs, Warren N. Schmidt, Thomas M. Kaufman, Jack T. Stapleton

PLoS Pathog. 2017 Feb; 13(2): e1006232. Published online 2017 Feb 24. doi: 10.1371/journal.ppat.1006232

PMCID:: PMC5342304

Abstract Article PDF–2.2M

Select item 44082442.

Linkage and association analysis of obesity traits reveals novel loci and interactions with dietary n-3 fatty acids in an Alaska Native (Yup’ik) population

Laura Kelly Vaughan, Howard W. Wiener, Stella Aslibekyan, David B. Allison, Peter J. Havel, Kimber L. Stanhope, Diane M. O’Brien, Scarlett E. Hopkins, Dominick J. Lemas, Bert B. Boyer, Hemant K. Tiwari

Metabolism. Author manuscript; available in PMC 2016 Jun 1.

Published in final edited form as: Metabolism. 2015 Jun; 64(6): 689–697. Published online 2015 Mar 5. doi: 10.1016/j.metabol.2015.02.008

PMCID:: PMC4408244

Abstract Article PDF–396K

Select item 1657293.

Dimerization In Vivo and Inhibition of the Nonreceptor Form of Protein Tyrosine Phosphatase Epsilon

Hila Toledano-Katchalski, Zohar Tiran, Tal Sines, Gidi Shani, Shira Granot-Attas, Jeroen den Hertog, Ari Elson

Mol Cell Biol. 2003 Aug; 23(15): 5460–5471. doi: 10.1128/MCB.23.15.5460-5471.2003

PMCID:: PMC165729

Abstract Article PDF–502K

Select item 403314.

Identification of a cytoplasmic, phorbol ester-inducible isoform of protein tyrosine phosphatase epsilon.

A Elson, P Leder

Proc Natl Acad Sci U S A. 1995 Dec 19; 92(26): 12235–12239. doi: 10.1073/pnas.92.26.12235

PMCID:: PMC40331

Summary Page Browse PDF–1.4M

Select item 3065945.

Hypomyelination and increased activity of voltage-gated K⁺ channels in mice lacking protein tyrosine phosphatase ε

A. Peretz, H. Gil-Henn, A. Sobko, V. Shinder, B. Attali, A. Elson

EMBO J. 2000 Aug 1; 19(15): 4036–4045. doi: 10.1093/emboj/19.15.4036

PMCID:: PMC306594

Abstract Article PDF–925K

Select item 32709976.

Epidermal Growth Factor Receptor (EGFR)-mediated Positive Feedback of Protein-tyrosine Phosphatase ϵ (PTPϵ) on ERK1/2 and AKT Protein Pathways Is Required for Survival of Human Breast Cancer Cells

Caroline E. Nunes-Xavier, Ari Elson, Rafael Pulido

J Biol Chem. 2012 Jan 27; 287(5): 3433–3444. Published online 2011 Nov 23. doi: 10.1074/jbc.M111.293928

PMCID:: PMC3270997

Abstract Article PDF–3.3M

Select item 5520567.

Structural diversity and evolution of human receptor-like protein tyrosine phosphatases.

N X Krueger, M Streuli, H Saito

EMBO J. 1990 Oct; 9(10): 3241–3252. doi: 10.1002/j.1460-2075.1990.tb07523.x

PMCID:: PMC552056

Summary Page Browse PDF–2.7M

Select item 24883738.

Genes to Diseases (G2D) Computational Method to Identify Asthma Candidate Genes

Karine Tremblay, Mathieu Lemire, Camille Potvin, Alexandre Tremblay, Gary M. Hunninghake, Benjamin A. Raby, Thomas J. Hudson, Carolina Perez-Iratxeta, Miguel A. Andrade-Navarro, Catherine Laprise

PLoS One. 2008; 3(8): e2907. Published online 2008 Aug 6. doi: 10.1371/journal.pone.0002907

PMCID:: PMC2488373

Abstract Article PDF–291K

Select item 28228679.

Novel HIV-1 Knockdown Targets Identified by an Enriched Kinases/Phosphatases shRNA Library Using a Long-Term Iterative Screen in Jurkat T-Cells

Sylvie Rato, Sara Maia, Paula M. Brito, Leonor Resende, Carina F. Pereira, Catarina Moita, Rui P. Freitas, José Moniz-Pereira, Nir Hacohen, Luis Ferreira Moita, Joao Goncalves

PLoS One. 2010; 5(2): e9276. Published online 2010 Feb 17. doi: 10.1371/journal.pone.0009276

PMCID:: PMC2822867

Abstract Article PDF–1.2M

Select item 199561510.

Genome-wide association with select biomarker traits in the Framingham Heart Study

Emelia J Benjamin, Josée Dupuis, Martin G Larson, Kathryn L Lunetta, Sarah L Booth, Diddahally R Govindaraju, Sekar Kathiresan, John F Keaney, Jr, Michelle J Keyes, Jing-Ping Lin, James B Meigs, Sander J Robins, Jian Rong, Renate Schnabel, Joseph A Vita, Thomas J Wang, Peter WF Wilson, Philip A Wolf, Ramachandran S Vasan

BMC Med Genet. 2007; 8(Suppl 1): S11. Published online 2007 Sep 19. doi: 10.1186/1471-2350-8-S1-S11

PMCID:: PMC1995615

Abstract Article PDF–356K

Select item 342948611.

Genome-Wide Association Study of d-Amphetamine Response in Healthy Volunteers Identifies Putative Associations, Including Cadherin 13 (CDH13)

Amy B. Hart, Barbara E. Engelhardt, Margaret C. Wardle, Greta Sokoloff, Matthew Stephens, Harriet de Wit, Abraham A. Palmer

PLoS One. 2012; 7(8): e42646. Published online 2012 Aug 28. doi: 10.1371/journal.pone.0042646

PMCID:: PMC3429486

Abstract Article PDF–711K

Select item 263802012.

Large-Scale Structural Analysis of the Classical Human Protein Tyrosine Phosphatome

Alastair J. Barr, Emilie Ugochukwu, Wen Hwa Lee, Oliver N.F. King, Panagis Filippakopoulos, Ivan Alfano, Pavel Savitsky, Nicola A. Burgess-Brown, Susanne Müller, Stefan Knapp

Cell. 2009 Jan 23; 136(2): 352–363. doi: 10.1016/j.cell.2008.11.038

PMCID:: PMC2638020

Abstract Article

Select item 702154913.

PTPRA Phosphatase Regulates GDNF-Dependent RET Signaling and Inhibits the RET Mutant MEN2A Oncogenic Potential

Leena Yadav, Elina Pietilä, Tiina Öhman, Xiaonan Liu, Arun K. Mahato, Yulia Sidorova, Kaisa Lehti, Mart Saarma, Markku Varjosalo

iScience. 2020 Feb 21; 23(2): 100871. Published online 2020 Jan 31. doi: 10.1016/j.isci.2020.100871

PMCID:: PMC7021549

Abstract Article PDF–8.1M

Select item 555729214.

Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions

Kyuho Han, Edwin E. Jeng, Gaelen T. Hess, David W. Morgens, Amy Li, Michael C. Bassik

Nat Biotechnol. Author manuscript; available in PMC 2017 Sep 20.

Published in final edited form as: Nat Biotechnol. 2017 May; 35(5): 463–474. Published online 2017 Mar 20. doi: 10.1038/nbt.3834

PMCID:: PMC5557292

Abstract Article PDF–3.4M

Select item 546865015.

Histone-binding of DPF2 mediates its repressive role in myeloid differentiation

Ferdinand M. Huber, Sarah M. Greenblatt, Andrew M. Davenport, Concepcion Martinez, Ye Xu, Ly P. Vu, Stephen D. Nimer, André Hoelz

Proc Natl Acad Sci U S A. 2017 Jun 6; 114(23): 6016–6021. Published online 2017 May 22. doi: 10.1073/pnas.1700328114

PMCID:: PMC5468650

Abstract Article PDF–1.3M

Select item 138022516.

A Scan of Chromosome 10 Identifies a Novel Locus Showing Strong Association with Late-Onset Alzheimer Disease

Andrew Grupe, Yonghong Li, Charles Rowland, Petra Nowotny, Anthony L. Hinrichs, Scott Smemo, John S. K. Kauwe, Taylor J. Maxwell, Sara Cherny, Lisa Doil, Kristina Tacey, Ryan van Luchene, Amanda Myers, Fabienne Wavrant-De Vrièze, Mona Kaleem, Paul Hollingworth, Luke Jehu, Catherine Foy, Nicola Archer, Gillian Hamilton, Peter Holmans, Chris M. Morris, Joseph Catanese, John Sninsky, Thomas J. White, John Powell, John Hardy, Michael O’Donovan, Simon Lovestone, Lesley Jones, John C. Morris, Leon Thal, Michael Owen, Julie Williams, Alison Goate

Am J Hum Genet. 2006 Jan; 78(1): 78–88. Published online 2005 Nov 15. doi: 10.1086/498851

PMCID:: PMC1380225

Abstract Article PDF–329K

Select item 501331517.

Defining the Protein-Protein Interaction Network of the Human Protein Tyrosine Phosphatase Family

Xu Li, Kim My Tran, Kathryn E. Aziz, Alexey V. Sorokin, Junjie Chen, Wenqi Wang

Mol Cell Proteomics. 2016 Sep; 15(9): 3030–3044. Published online 2016 Jul 18. doi: 10.1074/mcp.M116.060277

PMCID:: PMC5013315

Abstract Article PDF–3.2M

Select item 549522518.

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing

Teng Fei, Yiwen Chen, Tengfei Xiao, Wei Li, Laura Cato, Peng Zhang, Maura B. Cotter, Michaela Bowden, Rosina T. Lis, Shuang G. Zhao, Qiu Wu, Felix Y. Feng, Massimo Loda, Housheng Hansen He, X. Shirley Liu, Myles Brown

Proc Natl Acad Sci U S A. 2017 Jun 27; 114(26): E5207–E5215. Published online 2017 Jun 13. doi: 10.1073/pnas.1617467114

PMCID:: PMC5495225

Abstract Article PDF–1.3M

Select item 1015161519.

Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein–protein interactions in the human cell

Tara K. Bartolec, Xabier Vázquez-Campos, Alexander Norman, Clement Luong, Marcus Johnson, Richard J. Payne, Marc R. Wilkins, Joel P. Mackay, Jason K. K. Low

Proc Natl Acad Sci U S A. 2023 Apr 25; 120(17): e2219418120. Published online 2023 Apr 18. doi: 10.1073/pnas.2219418120

PMCID:: PMC10151615

Abstract Article PDF–2.9M

Select item 289646420.

Personalized Smoking Cessation: Interactions between Nicotine Dose, Dependence and Quit-Success Genotype Score

Jed E Rose, Frédérique M Behm, Tomas Drgon, Catherine Johnson, George R Uhl

Mol Med. 2010 Jul-Aug; 16(7-8): 247–253. Published online 2010 Mar 17. doi: 10.2119/molmed.2009.00159

Correction in:: Mol Med. 2012; 18(1): 729.

PMCID:: PMC2896464

Abstract Article PDF–2.4M

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