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Select item 109677331.

Identification and Validation of a PEX5-Dependent Signature for Prognostic Prediction in Glioma

Xuhui Qin, Bing Wang, Xia Lu, Yanyang Song, Wei Wang

Biomolecules. 2024 Mar; 14(3): 314. Published online 2024 Mar 6. doi: 10.3390/biom14030314

PMCID:: PMC10967733

Abstract Article PDF–11M

Select item 87418432.

Insights into the critical role of the PXR in preventing carcinogenesis and chemotherapeutic drug resistance

Xiaxia Niu, Ting Wu, Gege Li, Xinsheng Gu, Yanan Tian, Hongmei Cui

Int J Biol Sci. 2022; 18(2): 742–759. Published online 2022 Jan 1. doi: 10.7150/ijbs.68724

PMCID:: PMC8741843

Abstract Article PDF–1.7M

Select item 59380323.

PEX5 regulates autophagy via the mTORC1-TFEB axis during starvation

So Young Eun, Joon No Lee, In-Koo Nam, Zhi-qiang Liu, Hong-Seob So, Seong-Kyu Choe, RaeKil Park

Exp Mol Med. 2018 Apr; 50(4): 4. Published online 2018 Apr 6. doi: 10.1038/s12276-017-0007-8

PMCID:: PMC5938032

Abstract Article PDF–4.2M

Select item 50307144.

Recognition of a Functional Peroxisome Type 1 Target by the Dynamic Import Receptor Pex5p

Will A. Stanley, Fabian V. Filipp, Petri Kursula, Nicole Schüller, Ralf Erdmann, Wolfgang Schliebs, Michael Sattler, Matthias Wilmanns

Mol Cell. Author manuscript; available in PMC 2016 Sep 21.

Published in final edited form as: Mol Cell. 2006 Dec 8; 24(5): 653–663. doi: 10.1016/j.molcel.2006.10.024

PMCID:: PMC5030714

Abstract Article PDF–942K

Select item 43841155.

Molecular Recognition of PTS-1 Cargo Proteins by Pex5p: Implications for Protein Mistargeting in Primary Hyperoxaluria

Noel Mesa-Torres, Nenad Tomic, Armando Albert, Eduardo Salido, Angel L. Pey

Biomolecules. 2015 Mar; 5(1): 121–141. Published online 2015 Feb 13. doi: 10.3390/biom5010121

PMCID:: PMC4384115

Abstract Article PDF–39M

Select item 38941536.

PEX5 and Ubiquitin Dynamics on Mammalian Peroxisome Membranes

Aidan I. Brown, Peter K. Kim, Andrew D. Rutenberg

PLoS Comput Biol. 2014 Jan; 10(1): e1003426. Published online 2014 Jan 16. doi: 10.1371/journal.pcbi.1003426

PMCID:: PMC3894153

Abstract Article PDF–1.5M

Select item 37900147.

A Cargo-centered Perspective on the PEX5 Receptor-mediated Peroxisomal Protein Import Pathway

Tânia Francisco, Tony A. Rodrigues, Marta O. Freitas, Cláudia P. Grou, Andreia F. Carvalho, Clara Sá-Miranda, Manuel P. Pinto, Jorge E. Azevedo

J Biol Chem. 2013 Oct 4; 288(40): 29151–29159. Published online 2013 Aug 20. doi: 10.1074/jbc.M113.487140

PMCID:: PMC3790014

Abstract Article PDF–1.3M

Select item 27856528.

Mapping the Cargo Protein Membrane Translocation Step into the PEX5 Cycling Pathway

Inês S. Alencastre, Tony A. Rodrigues, Cláudia P. Grou, Marc Fransen, Clara Sá-Miranda, Jorge E. Azevedo

J Biol Chem. 2009 Oct 2; 284(40): 27243–27251. Published online 2009 Jul 23. doi: 10.1074/jbc.M109.032565

PMCID:: PMC2785652

Abstract Article PDF–1.7M

Select item 21339409.

Multiple PEX genes are required for proper subcellular distribution and stability of Pex5p, the PTS1 receptor: evidence that PTS1 protein import is mediated by a cycling receptor

J Cell Biol. 1996 Dec 2; 135(6): 1763–1774. doi: 10.1083/jcb.135.6.1763

PMCID:: PMC2133940

Summary PDF–2.9M

Select item 185490710.

A previously unobserved conformation for the human Pex5p receptor suggests roles for intrinsic flexibility and rigid domain motions in ligand binding

Will A Stanley, Niko V Pursiainen, Elspeth F Garman, André H Juffer, Matthias Wilmanns, Petri Kursula

BMC Struct Biol. 2007; 7: 24. Published online 2007 Apr 11. doi: 10.1186/1472-6807-7-24

PMCID:: PMC1854907

Abstract Article PDF–2.1M

Select item 12150911.

Peroxisome Targeting Signal Type 1 (PTS1) Receptor Is Involved in Import of Both PTS1 and PTS2: Studies with PEX5-Defective CHO Cell Mutants

Hidenori Otera, Kanji Okumoto, Keita Tateishi, Yuka Ikoma, Eiko Matsuda, Maki Nishimura, Toshiro Tsukamoto, Takashi Osumi, Kazumasa Ohashi, Osamu Higuchi, Yukio Fujiki

Mol Cell Biol. 1998 Jan; 18(1): 388–399. doi: 10.1128/mcb.18.1.388

PMCID:: PMC121509

Abstract Article PDF–5.1M

Select item 461771412.

Peroxisomal Import Reduces the Proapoptotic Activity of Deubiquitinating Enzyme USP2

Katharina Reglinski, Marina Keil, Sabrina Altendorf, Dominic Waithe, Christian Eggeling, Wolfgang Schliebs, Ralf Erdmann

PLoS One. 2015; 10(10): e0140685. Published online 2015 Oct 20. doi: 10.1371/journal.pone.0140685

PMCID:: PMC4617714

Abstract Article PDF–5.6M

Select item 449033713.

Revisiting the intraperoxisomal pathway of mammalian PEX7

Tony A. Rodrigues, Cláudia P. Grou, Jorge E. Azevedo

Sci Rep. 2015; 5: 11806. Published online 2015 Jul 3. doi: 10.1038/srep11806

PMCID:: PMC4490337

Abstract Article PDF–1.0M

Select item 387956614.

A Novel Pex14 Protein-interacting Site of Human Pex5 Is Critical for Matrix Protein Import into Peroxisomes

Alexander Neuhaus, Hamed Kooshapur, Janina Wolf, N. Helge Meyer, Tobias Madl, Jürgen Saidowsky, Eva Hambruch, Anissa Lazam, Martin Jung, Michael Sattler, Wolfgang Schliebs, Ralf Erdmann

J Biol Chem. 2014 Jan 3; 289(1): 437–448. Published online 2013 Nov 14. doi: 10.1074/jbc.M113.499707

PMCID:: PMC3879566

Abstract Article PDF–2.4M

Select item 262671715.

Crystal structure of the conserved N-terminal domain of the peroxisomal matrix protein import receptor, Pex14p

Jian-Rong Su, Kazuki Takeda, Shigehiko Tamura, Yukio Fujiki, Kunio Miki

Proc Natl Acad Sci U S A. 2009 Jan 13; 106(2): 417–421. Published online 2009 Jan 2. doi: 10.1073/pnas.0808681106

PMCID:: PMC2626717

Abstract Article PDF–879K

Select item 212051416.

Human peroxisomal targeting signal-1 receptor restores peroxisomal protein import in cells from patients with fatal peroxisomal disorders

J Cell Biol. 1995 Jul 1; 130(1): 51–65. doi: 10.1083/jcb.130.1.51

PMCID:: PMC2120514

Summary PDF–3.4M

Select item 121988017.

C-terminal tripeptide Ser-Asn-Leu (SNL) of human D-aspartate oxidase is a functional peroxisome-targeting signal.

L Amery, C Brees, M Baes, C Setoyama, R Miura, G P Mannaerts, P P Van Veldhoven

Biochem J. 1998 Dec 1; 336(Pt 2): 367–371. doi: 10.1042/bj3360367

PMCID:: PMC1219880

Summary PDF–193K

Select item 606519718.

Peroxisomal monoubiquitinated PEX5 interacts with the AAA ATPases PEX1 and PEX6 and is unfolded during its dislocation into the cytosol

Ana G. Pedrosa, Tânia Francisco, Diana Bicho, Ana F. Dias, Aurora Barros-Barbosa, Vera Hagmann, Gabriele Dodt, Tony A. Rodrigues, Jorge E. Azevedo

J Biol Chem. 2018 Jul 20; 293(29): 11553–11563. Published online 2018 Jun 8. doi: 10.1074/jbc.RA118.003669

PMCID:: PMC6065197

Abstract Article PDF–1.5M

Select item 560238919.

The peroxisomal matrix protein translocon is a large cavity-forming protein assembly into which PEX5 protein enters to release its cargo

Ana F. Dias, Tony A. Rodrigues, Ana G. Pedrosa, Aurora Barros-Barbosa, Tânia Francisco, Jorge E. Azevedo

J Biol Chem. 2017 Sep 15; 292(37): 15287–15300. Published online 2017 Aug 1. doi: 10.1074/jbc.M117.805044

PMCID:: PMC5602389

Abstract Article PDF–3.0M

Select item 501610120.

Super-resolution Microscopy Reveals Compartmentalization of Peroxisomal Membrane Proteins

Silvia Galiani, Dominic Waithe, Katharina Reglinski, Luis Daniel Cruz-Zaragoza, Esther Garcia, Mathias P. Clausen, Wolfgang Schliebs, Ralf Erdmann, Christian Eggeling

J Biol Chem. 2016 Aug 12; 291(33): 16948–16962. Published online 2016 Jun 16. doi: 10.1074/jbc.M116.734038

PMCID:: PMC5016101

Abstract Article PDF–4.5M

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PMC Links for Gene (Select 5830) (83)
PMC
PREDICTED: Homo sapiens coiled-coil alpha-helical rod protein 1 (CCHCR1), transc...
PREDICTED: Homo sapiens coiled-coil alpha-helical rod protein 1 (CCHCR1), transcript variant X10, mRNA
gi|2217361859|ref|XM_047418913.1|

Nucleotide
Homo sapiens peroxisomal biogenesis factor 5 (PEX5), transcript variant 13, mRNA
Homo sapiens peroxisomal biogenesis factor 5 (PEX5), transcript variant 13, mRNA
gi|1757649824|ref|NM_001351132.2|

Nucleotide
PREDICTED: Homo sapiens peroxisomal biogenesis factor 5 (PEX5), transcript varia...
PREDICTED: Homo sapiens peroxisomal biogenesis factor 5 (PEX5), transcript variant X17, mRNA
gi|2217290294|ref|XM_047429270.1|

Nucleotide

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