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Select item 71142951.

Overexpression of cell-cycle related and expression-elevated protein in tumor (CREPT) in malignant cervical cancer

Na Wen, Lihua Bian, Jing Gong, Yuanguang Meng

J Int Med Res. 2020 Jan; 48(1): 0300060519895089. Published online 2020 Jan 15. doi: 10.1177/0300060519895089

PMCID:: PMC7114295

Abstract Article PDF–536K

Select item 60213692.

CREPT facilitates colorectal cancer growth through inducing Wnt/β-catenin pathway by enhancing p300-mediated β-catenin acetylation

Yanquan Zhang, Shiyan Wang, Wei Kang, Chunxiao Liu, Yujuan Dong, Fangli Ren, Yinyin Wang, Jinglin Zhang, Guoping Wang, Ka Fai To, Xueji Zhang, Joseph JY Sung, Zhijie Chang, Jun Yu

Oncogene. 2018; 37(26): 3485–3500. Published online 2018 Mar 22. doi: 10.1038/s41388-018-0161-z

PMCID:: PMC6021369

Abstract Article PDF–7.0M

Select item 58911703.

Weimiao Li, Guoxu Zheng, Jinghua Xia, Guang Yang, Jianyong Sun, Xuejiao Wang, Miaomiao Wen, Ying Sun, Zhipei Zhang, Faguang Jin

Cancer Sci. 2018 Apr; 109(4): 1012–1023. Published online 2018 Mar 5. doi: 10.1111/cas.13524

PMCID:: PMC5891170

Abstract Article PDF–1.6M

Select item 57877824.

Overexpression of CREPT confers colorectal cancer sensitivity to fluorouracil

Yan-Shen Kuang, Yi Wang, Li-Dan Ding, Liu Yang, Ying Wang, Si-Han Liu, Bing-Tao Zhu, Xu-Ning Wang, Hong-Yi Liu, Jun Li, Zhi-Jie Chang, Yin-Yin Wang, Bao-Qing Jia

World J Gastroenterol. 2018 Jan 28; 24(4): 475–483. Published online 2018 Jan 28. doi: 10.3748/wjg.v24.i4.475

PMCID:: PMC5787782

Abstract Article PDF–1.7M

Select item 56265885.

Clinical and Genome Wide Analysis of Cisplatin-Induced Peripheral Neuropathy in Survivors of Adult-Onset Cancer

M. Eileen Dolan, Omar El Charif, Heather E. Wheeler, Eric R. Gamazon, Shirin Ardeshir-Rouhani-Fard, Patrick Monahan, Darren R. Feldman, Robert J. Hamilton, David J. Vaughn, Clair J. Beard, Chunkit Fung, Jeri Kim, Sophie D. Fossa, Daniel L Hertz, Taisei Mushiroda, Michiaki Kubo, Lawrence H. Einhorn, Nancy J. Cox, Lois B. Travis, for the Platinum Study Group

Clin Cancer Res. Author manuscript; available in PMC 2018 Oct 1.

Published in final edited form as: Clin Cancer Res. 2017 Oct 1; 23(19): 5757–5768. Published online 2017 Jun 13. doi: 10.1158/1078-0432.CCR-16-3224

PMCID:: PMC5626588

Abstract Article PDF–1.4M

Select item 42780826.

Characterization of a Monoclonal Antibody Against CREPT, a Novel Protein Highly Expressed in Tumors

Fangli Ren, Ruoke Wang, Yanquan Zhang, Chunxiao Liu, Yinyin Wang, Jim Hu, Linqi Zhang, Zhijie Chang

Monoclon Antib Immunodiagn Immunother. 2014 Dec 1; 33(6): 401–408. doi: 10.1089/mab.2014.0043

PMCID:: PMC4278082

Abstract Article PDF–664K

Select item 42301367.

CREPT expression correlates with poor prognosis in patients with retroperitoneal leiomyosarcoma

Yaoguang She, Jiao Liang, Lin Chen, Ying Qiu, Na Liu, Xudong Zhao, Xiaohui Huang, Yinyin Wang, Fangli Ren, Zhijie Chang, Peiyu Li

Int J Clin Exp Pathol. 2014; 7(10): 6596–6605. Published online 2014 Sep 15.

PMCID:: PMC4230136

Abstract Article PDF–1.1M

Select item 40056738.

Kub5-Hera, the human Rtt103 homolog, plays dual functional roles in transcription termination and DNA repair

Julio C. Morales, Patricia Richard, Amy Rommel, Farjana J. Fattah, Edward A. Motea, Praveen L. Patidar, Ling Xiao, Konstantin Leskov, Shwu-Yuan Wu, Walter N. Hittelman, Cheng-Ming Chiang, James L. Manley, David A. Boothman

Nucleic Acids Res. 2014 Apr; 42(8): 4996–5006. Published online 2014 Mar 3. doi: 10.1093/nar/gku160

PMCID:: PMC4005673

Abstract Article PDF–1.9M

Select item 63245359.

MicroRNA-383 acts as a tumor suppressor in colorectal cancer by modulating CREPT/RPRD1B expression

Jian Li, Amber R. Smith, Rebecca T. Marquez, Jun Li, Kun Li, Lan Lan, Xiaoqing Wu, Linxi Zhao, Fangli Ren, Yi Wang, Yinyin Wang, Baoqing Jia, Liang Xu, Zhijie Chang

Mol Carcinog. Author manuscript; available in PMC 2019 Oct 1.

Published in final edited form as: Mol Carcinog. 2018 Oct; 57(10): 1408–1420. Published online 2018 Jul 3. doi: 10.1002/mc.22866

PMCID:: PMC6324535

Abstract Article PDF–2.2M

Select item 477022510.

The Kub5-Hera/RPRD1B interactome: a novel role in preserving genetic stability by regulating DNA mismatch repair

Praveen L. Patidar, Edward A. Motea, Farjana J. Fattah, Yunyun Zhou, Julio C. Morales, Yang Xie, Harold R. Garner, David A. Boothman

Nucleic Acids Res. 2016 Feb 29; 44(4): 1718–1731. Published online 2016 Jan 26. doi: 10.1093/nar/gkv1492

PMCID:: PMC4770225

Abstract Article PDF–3.5M

Select item 780152811.

CREPT is required for murine stem cell maintenance during intestinal regeneration

Liu Yang, Haiyan Yang, Yunxiang Chu, Yunhao Song, Lidan Ding, Bingtao Zhu, Wanli Zhai, Xuning Wang, Yanshen Kuang, Fangli Ren, Baoqing Jia, Wei Wu, Xiongjun Ye, Yinyin Wang, Zhijie Chang

Nat Commun. 2021; 12: 270. Published online 2021 Jan 11. doi: 10.1038/s41467-020-20636-9

PMCID:: PMC7801528

Abstract Article PDF–9.9M

Select item 628161512.

CREPT/RPRD1B associates with Aurora B to regulate Cyclin B1 expression for accelerating the G2/M transition in gastric cancer

Lidan Ding, Liu Yang, Yuqi He, Bingtao Zhu, Fangli Ren, Xuanzi Fan, Yinyin Wang, Mengdi Li, Jun Li, Yanshen Kuang, Sihan Liu, Wanli Zhai, Danhui Ma, Yanfang Ju, Quentin Liu, Baoqing Jia, Jianqiu Sheng, Zhijie Chang

Cell Death Dis. 2018 Dec; 9(12): 1172. Published online 2018 Dec 5. doi: 10.1038/s41419-018-1211-8

PMCID:: PMC6281615

Abstract Article PDF–3.1M

Select item 537831813.

Knocking-down of CREPT prohibits the progression of oral squamous cell carcinoma and suppresses cyclin D1 and c-Myc expression

Juntao Ma, Yipeng Ren, Lei Zhang, Xiangpan Kong, Tong Wang, Yueyi Shi, Rongfa Bu

PLoS One. 2017; 12(4): e0174309. Published online 2017 Apr 3. doi: 10.1371/journal.pone.0174309

PMCID:: PMC5378318

Abstract Article PDF–3.1M

Select item 952087914.

Long non-coding RNA NEAT1 mediated RPRD1B stability facilitates fatty acid metabolism and lymph node metastasis via c-Jun/c-Fos/SREBP1 axis in gastric cancer

Yongxu Jia, Qian Yan, Yinli Zheng, Lei Li, Baifeng Zhang, Zhiwei Chang, Zehua Wang, Hong Tang, Yanru Qin, Xin-Yuan Guan

J Exp Clin Cancer Res. 2022; 41: 287. Published online 2022 Sep 29. doi: 10.1186/s13046-022-02449-4

PMCID:: PMC9520879

Abstract Article PDF–16M

Select item 803903115.

CREPT/RPRD1B promotes tumorigenesis through STAT3-driven gene transcription in a p300-dependent manner

Wanli Zhai, Xiongjun Ye, Yinyin Wang, Yarui Feng, Ying Wang, Yuting Lin, Lidan Ding, Liu Yang, Xuning Wang, Yanshen Kuang, Xinyuan Fu, Y. Eugene Chin, Baoqing Jia, Bingtao Zhu, Fangli Ren, Zhijie Chang

Br J Cancer. 2021 Apr 12; 124(8): 1437–1448. Published online 2021 Feb 3. doi: 10.1038/s41416-021-01269-1

PMCID:: PMC8039031

Abstract Article PDF–2.9M

Select item 658846316.

Crosstalk between RNA Pol II C-Terminal Domain Acetylation and Phosphorylation via RPRD Proteins

Ibraheem Ali, Diego Garrido Ruiz, Zuyao Ni, Jeffrey R. Johnson, Heng Zhang, Pao-Chen Li, Mir M. Khalid, Ryan J. Conrad, Xinghua Guo, Jinrong Min, Jack Greenblatt, Matthew Jacobson, Nevan J. Krogan, Melanie Ott

Mol Cell. Author manuscript; available in PMC 2020 Jun 20.

Published in final edited form as: Mol Cell. 2019 Jun 20; 74(6): 1164–1174.e4. Published online 2019 May 1. doi: 10.1016/j.molcel.2019.04.008

PMCID:: PMC6588463

Abstract Article PDF–2.2M

Select item 413276717.

CREPT/RPRD1B, a Recently Identified Novel Protein Highly Expressed in Tumors, Enhances the β-Catenin·TCF4 Transcriptional Activity in Response to Wnt Signaling

Yanquan Zhang, Chunxiao Liu, Xiaolin Duan, Fangli Ren, Shan Li, Zhe Jin, Yinyin Wang, Yarui Feng, Zewen Liu, Zhijie Chang

J Biol Chem. 2014 Aug 15; 289(33): 22589–22599. Published online 2014 Jun 30. doi: 10.1074/jbc.M114.560979

PMCID:: PMC4132767

Abstract Article PDF–3.4M

Select item 412403518.

RPRD1A and RPRD1B Are Human RNA Polymerase II C-Terminal Domain Scaffolds for Ser5 Dephosphorylation

Zuyao Ni, Chao Xu, Xinghua Guo, Gerald O. Hunter, Olga V. Kuznetsova, Wolfram Tempel, Edyta Marcon, Guoqing Zhong, Hongbo Guo, Wei-Hung William Kuo, Joyce Li, Peter Young, Jonathan B. Olsen, Cuihong Wan, Peter Loppnau, Majida El Bakkouri, Guillermo A. Senisterra, Hao He, Haiming Huang, Sachdev S. Sidhu, Andrew Emili, Shona Murphy, Amber L. Mosley, Cheryl H. Arrowsmith, Jinrong Min, Jack F. Greenblatt

Nat Struct Mol Biol. Author manuscript; available in PMC 2015 Feb 1.

Published in final edited form as: Nat Struct Mol Biol. 2014 Aug; 21(8): 686–695. Published online 2014 Jul 6. doi: 10.1038/nsmb.2853

PMCID:: PMC4124035

Abstract Article PDF–2.0M

Select item 326578219.

Control of the RNA polymerase II phosphorylation state in promoter regions by CTD interaction domain-containing proteins RPRD1A and RPRD1B

Zuyao Ni, Jonathan B Olsen, Xinghua Guo, Guoqing Zhong, Eric Dongliang Ruan, Edyta Marcon, Peter Young, Hongbo Guo, Joyce Li, Jason Moffat, Andrew Emili, Jack F Greenblatt

Transcription. 2011 Sep-Oct; 2(5): 237–242. Published online 2011 Sep 1. doi: 10.4161/trns.2.5.17803

PMCID:: PMC3265782

Abstract Article PDF–1.7M

Select item 520725120.

URI Regulates KAP1 Phosphorylation and Transcriptional Repression via PP2A Phosphatase in Prostate Cancer Cells

Paolo Mita, Jeffrey N. Savas, Erica M. Briggs, Susan Ha, Veena Gnanakkan, John R. Yates, III, Diane M. Robins, Gregory David, Jef D. Boeke, Michael J. Garabedian, Susan K. Logan

J Biol Chem. 2016 Dec 2; 291(49): 25516–25528. Published online 2016 Oct 25. doi: 10.1074/jbc.M116.741660

PMCID:: PMC5207251

Abstract Article PDF–1.4M

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