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Select item 37952231.

Regulated Capture by Exosomes of mRNAs for Cytoplasmic tRNA Synthetases

Feng Wang, Zhiwen Xu, Jie Zhou, Wing-Sze Lo, Ching-Fun Lau, Leslie A. Nangle, Xiang-Lei Yang, Mingjie Zhang, Paul Schimmel

J Biol Chem. 2013 Oct 11; 288(41): 29223–29228. Published online 2013 Sep 3. doi: 10.1074/jbc.C113.490599

PMCID:: PMC3795223

Abstract Article PDF–1.1M

Select item 34339232.

Comparative Large Scale Characterization of Plant versus Mammal Proteins Reveals Similar and Idiosyncratic N-α-Acetylation Features

Willy V. Bienvenut, David Sumpton, Aude Martinez, Sergio Lilla, Christelle Espagne, Thierry Meinnel, Carmela Giglione

Mol Cell Proteomics. 2012 Jun; 11(6): M111.015131. Published online 2012 Jan 5. doi: 10.1074/mcp.M111.015131

PMCID:: PMC3433923

Abstract Article PDF–1.6M

Select item 48383733.

The crystal structure of human GlnRS provides basis for the development of neurological disorders

Jana Ognjenović, Jiang Wu, Doreen Matthies, Ulrich Baxa, Sriram Subramaniam, Jiqiang Ling, Miljan Simonović

Nucleic Acids Res. 2016 Apr 20; 44(7): 3420–3431. Published online 2016 Feb 10. doi: 10.1093/nar/gkw082

PMCID:: PMC4838373

Abstract Article PDF–3.8M

Select item 42103314.

Structure of the ArgRS–GlnRS–AIMP1 complex and its implications for mammalian translation

Yaoyao Fu, Youngran Kim, Kyeong Sik Jin, Hyun Sook Kim, Jong Hyun Kim, DongMing Wang, Minyoung Park, Chang Hwa Jo, Nam Hoon Kwon, Doyeun Kim, Myung Hee Kim, Young Ho Jeon, Kwang Yeon Hwang, Sunghoon Kim, Yunje Cho

Proc Natl Acad Sci U S A. 2014 Oct 21; 111(42): 15084–15089. Published online 2014 Oct 6. doi: 10.1073/pnas.1408836111

PMCID:: PMC4210331

Abstract Article PDF–1.3M

Select item 39804245.

Mutations in QARS, Encoding Glutaminyl-tRNA Synthetase, Cause Progressive Microcephaly, Cerebral-Cerebellar Atrophy, and Intractable Seizures

Xiaochang Zhang, Jiqiang Ling, Giulia Barcia, Lili Jing, Jiang Wu, Brenda J. Barry, Ganeshwaran H. Mochida, R. Sean Hill, Jill M. Weimer, Quinn Stein, Annapurna Poduri, Jennifer N. Partlow, Dorothée Ville, Olivier Dulac, Tim W. Yu, Anh-Thu N. Lam, Sarah Servattalab, Jacqueline Rodriguez, Nathalie Boddaert, Arnold Munnich, Laurence Colleaux, Leonard I. Zon, Dieter Söll, Christopher A. Walsh, Rima Nabbout

Am J Hum Genet. 2014 Apr 3; 94(4): 547–558. doi: 10.1016/j.ajhg.2014.03.003

PMCID:: PMC3980424

Abstract Article PDF–2.3M

Select item 96435146.

Regulation of BRCA1 stability through the tandem UBX domains of isoleucyl-tRNA synthetase 1

Scisung Chung, Mi-Sun Kang, Dauren S. Alimbetov, Gil-Im Mun, Na-Oh Yunn, Yunjin Kim, Byung-Gyu Kim, Minwoo Wie, Eun A. Lee, Jae Sun Ra, Jung-Min Oh, Donghyun Lee, Keondo Lee, Jihan Kim, Seung Hyun Han, Kyong-Tai Kim, Wan Kyun Chung, Ki Hyun Nam, Jaehyun Park, ByungHoon Lee, Sunghoon Kim, Weixing Zhao, Sung Ho Ryu, Yun-Sil Lee, Kyungjae Myung, Yunje Cho

Nat Commun. 2022; 13: 6732. Published online 2022 Nov 8. doi: 10.1038/s41467-022-34612-y

PMCID:: PMC9643514

Abstract Article PDF–2.1M

Select item 446687.

Evolution of the Glx-tRNA synthetase family: the glutaminyl enzyme as a case of horizontal gene transfer.

V Lamour, S Quevillon, S Diriong, V C N'Guyen, M Lipinski, M Mirande

Proc Natl Acad Sci U S A. 1994 Aug 30; 91(18): 8670–8674. doi: 10.1073/pnas.91.18.8670

PMCID:: PMC44668

Summary Page Browse PDF–1.5M

Select item 444158.

Human cytoplasmic isoleucyl-tRNA synthetase: selective divergence of the anticodon-binding domain and acquisition of a new structural unit.

K Shiba, N Suzuki, K Shigesada, Y Namba, P Schimmel, T Noda

Proc Natl Acad Sci U S A. 1994 Aug 2; 91(16): 7435–7439. doi: 10.1073/pnas.91.16.7435

PMCID:: PMC44415

Summary Page Browse PDF–1.7M

Select item 21748469.

Nucleolar Localization of Human Methionyl–Trna Synthetase and Its Role in Ribosomal RNA Synthesis

Young-Gyu Ko, Young-Sun Kang, Eun-Kyoung Kim, Sang Gyu Park, Sunghoon Kim

J Cell Biol. 2000 May 1; 149(3): 567–574. doi: 10.1083/jcb.149.3.567

PMCID:: PMC2174846

Abstract Article PDF–405K

Select item 267947610.

Dynamic Organization of Aminoacyl-tRNA Synthetase Complexes in the Cytoplasm of Human Cells

Monika Kaminska, Svitlana Havrylenko, Paulette Decottignies, Pierre Le Maréchal, Boris Negrutskii, Marc Mirande

J Biol Chem. 2009 May 15; 284(20): 13746–13754. doi: 10.1074/jbc.M900480200

PMCID:: PMC2679476

Abstract Article PDF–569K

Select item 434998611.

KCMF1 (potassium channel modulatory factor 1) Links RAD6 to UBR4 (ubiquitin N-recognin domain-containing E3 ligase 4) and Lysosome-Mediated Degradation

Jenny H. Hong, Lilia Kaustov, Etienne Coyaud, Tharan Srikumar, Janet Wan, Cheryl Arrowsmith, Brian Raught

Mol Cell Proteomics. 2015 Mar; 14(3): 674–685. Published online 2015 Jan 12. doi: 10.1074/mcp.M114.042168

PMCID:: PMC4349986

Abstract Article PDF–3.4M

Select item 470715812.

SENP3 regulates the global protein turnover and the Sp1 level via antagonizing SUMO2/3-targeted ubiquitination and degradation

Ming Wang, Jing Sang, Yanhua Ren, Kejia Liu, Xinyi Liu, Jian Zhang, Haolu Wang, Jian Wang, Amir Orian, Jie Yang, Jing Yi

Protein Cell. 2016 Jan; 7(1): 63–77. Published online 2015 Oct 28. doi: 10.1007/s13238-015-0216-7

PMCID:: PMC4707158

Abstract Article PDF–1.3M

Select item 850098013.

CCAT1/FABP5 promotes tumour progression through mediating fatty acid metabolism and stabilizing PI3K/AKT/mTOR signalling in lung adenocarcinoma

Jing Chen, Yaser Alduais, Kai Zhang, Xiaoli Zhu, Baoan Chen

J Cell Mol Med. 2021 Oct; 25(19): 9199–9213. Published online 2021 Aug 25. doi: 10.1111/jcmm.16815

PMCID:: PMC8500980

Abstract Article PDF–2.7M

Select item 613843914.

SHLD2/FAM35A co‐operates with REV7 to coordinate DNA double‐strand break repair pathway choice

Steven Findlay, John Heath, Vincent M Luo, Abba Malina, Théo Morin, Yan Coulombe, Billel Djerir, Zhigang Li, Arash Samiei, Estelle Simo‐Cheyou, Martin Karam, Halil Bagci, Dolev Rahat, Damien Grapton, Elise G Lavoie, Christian Dove, Husam Khaled, Hellen Kuasne, Koren K Mann, Kathleen Oros Klein, Celia M Greenwood, Yuval Tabach, Morag Park, Jean‐Francois Côté, Jean‐Yves Masson, Alexandre Maréchal, Alexandre Orthwein

EMBO J. 2018 Sep 14; 37(18): e100158. Published online 2018 Aug 28. doi: 10.15252/embj.2018100158

PMCID:: PMC6138439

Abstract Article PDF–1.1M

Select item 469352515.

Ubiquitin‐Activated Interaction Traps (UBAITs) identify E3 ligase binding partners

Hazel F O'Connor, Nancy Lyon, Justin W Leung, Poonam Agarwal, Caleb D Swaim, Kyle M Miller, Jon M Huibregtse

EMBO Rep. 2015 Dec; 16(12): 1699–1712. Published online 2015 Oct 27. doi: 10.15252/embr.201540620

PMCID:: PMC4693525

Abstract Article PDF–693K

Select item 1085081816.

Cancer‐associated FBXW7 loss is synthetic lethal with pharmacological targeting of CDC7

Joseph S. Baxter, Rachel Brough, Dragomir B. Krastev, Feifei Song, Sandhya Sridhar, Aditi Gulati, John Alexander, Theodoros I. Roumeliotis, Zuza Kozik, Jyoti S. Choudhary, Syed Haider, Stephen J. Pettitt, Andrew N. J. Tutt, Christopher J. Lord

Mol Oncol. 2024 Feb; 18(2): 369–385. Published online 2023 Oct 22. doi: 10.1002/1878-0261.13537

PMCID:: PMC10850818

Abstract Article PDF–2.7M

Select item 690492417.

MET Inhibitors Promote Liver Tumor Evasion of the Immune Response by Stabilizing PDL1

Hui Li, Chia-Wei Li, Xiaoqiang Li, Qingqing Ding, Lei Guo, Shuang Liu, Chunxiao Liu, Chien-Chen Lai, Jung-Mao Hsu, Qiongzhu Dong, Weiya Xia, Jennifer L. Hsu, Hirohito Yamaguchi, Yi Du, Yun-Ju Lai, Xian Sun, Paul B. Koller, Qinghai Ye, Mien-Chie Hung

Gastroenterology. Author manuscript; available in PMC 2020 May 1.

Published in final edited form as: Gastroenterology. 2019 May; 156(6): 1849–1861.e13. Published online 2019 Jan 31. doi: 10.1053/j.gastro.2019.01.252

PMCID:: PMC6904924

Abstract Article PDF–2.0M

Select item 451045418.

Quantitative analysis of PPT1 interactome in human neuroblastoma cells

Enzo Scifo, Agnieszka Szwajda, Rabah Soliymani, Francesco Pezzini, Marzia Bianchi, Arvydas Dapkunas, Janusz Dębski, Kristiina Uusi-Rauva, Michał Dadlez, Anne-Claude Gingras, Jaana Tyynelä, Alessandro Simonati, Anu Jalanko, Marc H. Baumann, Maciej Lalowski

Data Brief. 2015 Sep; 4: 207–216. Published online 2015 Jun 12. doi: 10.1016/j.dib.2015.05.016

PMCID:: PMC4510454

Abstract Article PDF–2.8M

Select item 998681719.

METTL3 protects METTL14 from STUB1‐mediated degradation to maintain m⁶A homeostasis

Zhan‐Cheng Zeng, Qi Pan, Yu‐Meng Sun, Heng‐Jing Huang, Xiao‐Tong Chen, Tian‐Qi Chen, Bo He, Hua Ye, Shun‐Xin Zhu, Ke‐Jia Pu, Ke Fang, Wei Huang, Yue‐Qin Chen, Wen‐Tao Wang

EMBO Rep. 2023 Mar; 24(3): e55762. Published online 2023 Jan 4. doi: 10.15252/embr.202255762

PMCID:: PMC9986817

Abstract Article PDF–3.5M

Select item 584947820.

Nuclear lamina genetic variants, including a truncated LAP2, in twins and siblings with nonalcoholic fatty liver disease

Graham F. Brady, Raymond Kwan, Peter J. Ulintz, Phirum Nguyen, Shirin Bassirian, Venkatesha Basrur, Alexey I. Nesvizhskii, Rohit Loomba, M. Bishr Omary

Hepatology. Author manuscript; available in PMC 2019 May 1.

Published in final edited form as: Hepatology. 2018 May; 67(5): 1710–1725. Published online 2018 Mar 24. doi: 10.1002/hep.29522

PMCID:: PMC5849478

Abstract Article PDF–1.7M

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PMC Links for Gene (Select 5859) (123)
PMC
cytochrome oxidase subunit 1, partial (mitochondrion) [Canalirogas sp. ASQSR078-...
cytochrome oxidase subunit 1, partial (mitochondrion) [Canalirogas sp. ASQSR078-11]
gi|344186949|gb|AEM96542.1|

Protein
Homo sapiens glutaminyl-tRNA synthetase 1 (QARS1), transcript variant 1, mRNA
Homo sapiens glutaminyl-tRNA synthetase 1 (QARS1), transcript variant 1, mRNA
gi|1519316029|ref|NM_005051.3|

Nucleotide

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