PMC Links for Gene (Select 5868) - PMC

Result Filters

Links from Gene

Items: 1 to 20 of 214

<< First< Prev

Page of 11

Next >Last >>

Select item 107562751.

A genome-wide CRISPR/Cas9 screen identifies a role for Rab5A and early endosomes in hepatitis E virus replication

Noémie Oechslin, Nathalie Da Silva, Maliki Ankavay, Darius Moradpour, Jérôme Gouttenoire

Proc Natl Acad Sci U S A. 2023 Dec 26; 120(52): e2307423120. Published online 2023 Dec 18. doi: 10.1073/pnas.2307423120

PMCID:: PMC10756275

Abstract Article PDF–7.2M

Select item 106147172.

Hepatitis B virus promotes its own replication by enhancing RAB5A-mediated dual activation of endosomal and autophagic vesicle pathways

Zhenyu Zhao, Zhen Wei, Jiaxin Zheng, Zhihong Li, Hecun Zou, Xiang Wen, Fahong Li, Xueyu Wang, Qian Huang, Huaqing Zeng, Hui Fan, Xuefei Cai, Jiming Zhang, Bei Jia, Ailong Huang, Mengji Lu, Yong Lin

Emerg Microbes Infect. 2023; 12(2): 2261556. Published online 2023 Sep 19. doi: 10.1080/22221751.2023.2261556

PMCID:: PMC10614717

Abstract Article PDF–4.7M

Select item 77328123.

The G-Protein Rab5A Activates VPS34 Complex II, a Class III PI3K, by a Dual Regulatory Mechanism

Thomas C. Buckles, Yohei Ohashi, Shirley Tremel, Stephen H. McLaughlin, Els Pardon, Jan Steyaert, Moshe T. Gordon, Roger L. Williams, Joseph J. Falke

Biophys J. 2020 Dec 1; 119(11): 2205–2218. Published online 2020 Oct 31. doi: 10.1016/j.bpj.2020.10.028

PMCID:: PMC7732812

Abstract Article PDF–1.3M

Select item 67483764.

Subversion of RAB5-regulated autophagy by the intracellular pathogen Ehrlichia chaffeensis

Yasuko Rikihisa

Small GTPases. 2019 Sep; 10(5): 343–349. Published online 2017 Jul 5. doi: 10.1080/21541248.2017.1332506

PMCID:: PMC6748376

Abstract Article PDF–579K

Select item 65482915.

Recognition and stabilization of geranylgeranylated human Rab5 by the GDP Dissociation Inhibitor (GDI)

Eileen Edler, Matthias Stein

Small GTPases. 2019 May; 10(3): 227–242. Published online 2017 Oct 25. doi: 10.1080/21541248.2017.1371268

PMCID:: PMC6548291

Abstract Article PDF–2.4M

Select item 64330786.

A single discrete Rab5-binding site in phosphoinositide 3-kinase β is required for tumor cell invasion

Samantha D. Heitz, David J. Hamelin, Reece M. Hoffmann, Nili Greenberg, Gilbert Salloum, Zahra Erami, Bassem D. Khalil, Aliaksei Shymanets, Elizabeth A. Steidle, Grace Q. Gong, Bernd Nürnberg, John E. Burke, Jack U. Flanagan, Anne R. Bresnick, Jonathan M. Backer

J Biol Chem. 2019 Mar 22; 294(12): 4621–4633. Published online 2019 Jan 18. doi: 10.1074/jbc.RA118.006032

PMCID:: PMC6433078

Abstract Article PDF–3.3M

Select item 60101097.

Probing the druggability of membrane-bound Rab5 by molecular dynamics simulations

Eileen Edler, Matthias Stein

J Enzyme Inhib Med Chem. 2017; 32(1): 434–443. Published online 2017 Jan 16. doi: 10.1080/14756366.2016.1260564

PMCID:: PMC6010109

Abstract Article PDF–1.3M

Select item 56469948.

Rab5a is overexpressed in oral cancer and promotes invasion through ERK/MMP signaling

Di Zhang, Changlong Lu, Hongjun Ai

Mol Med Rep. 2017 Oct; 16(4): 4569–4576. Published online 2017 Aug 10. doi: 10.3892/mmr.2017.7214

PMCID:: PMC5646994

Abstract Article PDF–1.5M

Select item 56247819.

Site-specific monoubiquitination downregulates Rab5 by disrupting effector binding and guanine nucleotide conversion

Donghyuk Shin, Wooju Na, Ji-Hyung Lee, Gyuhee Kim, Jiseok Baek, Seok Hee Park, Cheol Yong Choi, Sangho Lee

eLife. 2017; 6: e29154. Published online 2017 Oct 2. doi: 10.7554/eLife.29154

PMCID:: PMC5624781

Abstract Article PDF–3.4M

Select item 559646410.

Role of Rab5 in the formation of macrophage-derived foam cell

Lokwern Chan, Jin Hong, Junjie Pan, Jian Li, Zhichao Wen, Haiming Shi, Jianping Ding, Xinping Luo

Lipids Health Dis. 2017; 16: 170. Published online 2017 Sep 12. doi: 10.1186/s12944-017-0559-6

PMCID:: PMC5596464

Abstract Article PDF–2.6M

Select item 484889911.

The Autophagic Process Occurs in Human Bone Metastasis and Implicates Molecular Mechanisms Differently Affected by Rab5a in the Early and Late Stages

Paola Maroni, Paola Bendinelli, Massimo Resnati, Emanuela Matteucci, Enrico Milan, Maria Alfonsina Desiderio

Int J Mol Sci. 2016 Apr; 17(4): 443. Published online 2016 Mar 25. doi: 10.3390/ijms17040443

PMCID:: PMC4848899

Abstract Article PDF–6.5M

Select item 482716112.

Rab5-mediated VE-cadherin internalization regulates the barrier function of the lung microvascular endothelium

Junjun Yang, Wei Yao, Guisheng Qian, Zhenghua Wei, Guangyu Wu, Guansong Wang

Cell Mol Life Sci. 2015 Dec; 72(24): 4849–4866. Published online 2015 Jun 26. doi: 10.1007/s00018-015-1973-4

PMCID:: PMC4827161

Abstract Article PDF–8.0M

Select item 465074613.

Intracellular oxygen determined by respiration regulates localization of Ras and prenylated proteins

A Kim, R Davis, M Higuchi

Cell Death Dis. 2015 Jul; 6(7): e1825. Published online 2015 Jul 16. doi: 10.1038/cddis.2015.64

PMCID:: PMC4650746

Abstract Article PDF–2.3M

Select item 452592014.

Increased expression of Rab5A predicts metastasis and poor prognosis in colorectal cancer patients

Min-Hao Yu, Yang Luo, Shao-Lan Qin, Ming Zhong

Int J Clin Exp Pathol. 2015; 8(6): 6974–6980. Published online 2015 Jun 1.

PMCID:: PMC4525920

Abstract Article PDF–773K

Select item 450272715.

Vacuolin-1 potently and reversibly inhibits autophagosome-lysosome fusion by activating RAB5A

Yingying Lu, Shichen Dong, Baixia Hao, Chang Li, Kaiyuan Zhu, Wenjing Guo, Qian Wang, King-Ho Cheung, Connie WM Wong, Wu-Tian Wu, Huss Markus, Jianbo Yue

Autophagy. 2014 Nov; 10(11): 1895–1905. Published online 2014 Oct 30. doi: 10.4161/auto.32200

Correction in:: Autophagy. 2018; 14(1): 176–177.

PMCID:: PMC4502727

Abstract Article PDF–887K

Select item 448955016.

Yersinia Entry into Host Cells Requires Rab5-Dependent Dephosphorylation of PI(4,5)P₂ and Membrane Scission

Helen Sarantis, Daniel M. Balkin, Pietro De Camilli, Ralph R. Isberg, John H. Brumell, Sergio Grinstein

Cell Host Microbe. Author manuscript; available in PMC 2015 Jul 2.

Published in final edited form as: Cell Host Microbe. 2012 Feb 16; 11(2): 117–128. doi: 10.1016/j.chom.2012.01.010

PMCID:: PMC4489550

Abstract Article PDF–734K

Select item 447913617.

The role of Rab5a GTPase in endocytosis and post-endocytic trafficking of the hCG-human luteinizing hormone receptor complex

Thippeswamy Gulappa, Christine L. Clouser, K. M. J. Menon

Cell Mol Life Sci. 2011 Aug; 68(16): 2785–2795. Published online 2010 Nov 23. doi: 10.1007/s00018-010-0594-1

PMCID:: PMC4479136

Abstract Article PDF–523K

Select item 411456118.

Rab5 activation as a tumor cell migration switch

Pablo Mendoza, Jorge Díaz, Patricio Silva, Vicente A Torres

Small GTPases. 2014; 5: e28195. Published online 2014 Mar 20. doi: 10.4161/sgtp.28195

PMCID:: PMC4114561

Abstract Article PDF–2.0M

Select item 410778119.

A RAB5/RAB4 recycling circuitry induces a proteolytic invasive program and promotes tumor dissemination

Emanuela Frittoli, Andrea Palamidessi, Paola Marighetti, Stefano Confalonieri, Fabrizio Bianchi, Chiara Malinverno, Giovanni Mazzarol, Giuseppe Viale, Ines Martin-Padura, Massimilliano Garré, Dario Parazzoli, Valentina Mattei, Salvatore Cortellino, Giovanni Bertalot, Pier Paolo Di Fiore, Giorgio Scita

J Cell Biol. 2014 Jul 21; 206(2): 307–328. doi: 10.1083/jcb.201403127