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Select item 94733601.

Variant-specific changes in RAC3 function disrupt corticogenesis in neurodevelopmental phenotypes

Marcello Scala, Masashi Nishikawa, Hidenori Ito, Hidenori Tabata, Tayyaba Khan, Andrea Accogli, Laura Davids, Anna Ruiz, Pietro Chiurazzi, Gabriella Cericola, Björn Schulte, Kristin G Monaghan, Amber Begtrup, Annalaura Torella, Michele Pinelli, Anne Sophie Denommé-Pichon, Antonio Vitobello, Caroline Racine, Maria Margherita Mancardi, Courtney Kiss, Andrea Guerin, Wendy Wu, Elisabeth Gabau Vila, Bryan C Mak, Julian A Martinez-Agosto, Michael B Gorin, Bugrahan Duz, Yavuz Bayram, Claudia M B Carvalho, Jaime E Vengoechea, David Chitayat, Tiong Yang Tan, Bert Callewaert, Bernd Kruse, Lynne M Bird, Laurence Faivre, Marcella Zollino, Saskia Biskup, Undiagnosed Diseases Network , Telethon Undiagnosed Diseases Program , Pasquale Striano, Vincenzo Nigro, Mariasavina Severino, Valeria Capra, Gregory Costain, Koh ichi Nagata

Brain. 2022 Sep; 145(9): 3308–3327. Published online 2022 Jul 4. doi: 10.1093/brain/awac106

PMCID:: PMC9473360

Article PDF–2.2M

Select item 82621642.

Rac3 Expression and its Clinicopathological Significance in Patients With Bladder Cancer

Mei Chen, Zhenyu Nie, Hui Cao, Yuanhui Gao, Xiaohong Wen, Chong Zhang, Shufang Zhang

Pathol Oncol Res. 2021; 27: 598460. Published online 2021 Mar 30. doi: 10.3389/pore.2021.598460

PMCID:: PMC8262164

Article PDF–2.2M

Select item 35763593.

Rac3 induces a molecular pathway triggering breast cancer cell aggressiveness: differences in MDA-MB-231 and MCF-7 breast cancer cell lines

Caroline Gest, Ulrich Joimel, Limin Huang, Linda-Louise Pritchard, Alexandre Petit, Charlène Dulong, Catherine Buquet, Chao-Quan Hu, Pezhman Mirshahi, Marc Laurent, Françoise Fauvel-Lafève, Lionel Cazin, Jean-Pierre Vannier, He Lu, Jeannette Soria, Hong Li, Rémi Varin, Claudine Soria

BMC Cancer. 2013; 13: 63. Published online 2013 Feb 6. doi: 10.1186/1471-2407-13-63

PMCID:: PMC3576359

Article PDF–1.8M

Select item 31863844.

A Role for Rac3 GTPase in the Regulation of Autophagy

Wan Long Zhu, Mohammed S. Hossain, Dian Yan Guo, Sen Liu, Honglian Tong, Atefeh Khakpoor, Patrick J. Casey, Mei Wang

J Biol Chem. 2011 Oct 7; 286(40): 35291–35298. Published online 2011 Aug 18. doi: 10.1074/jbc.M111.280990

PMCID:: PMC3186384

Article PDF–1.5M

Select item 266375.

Endogenous, hyperactive Rac3 controls proliferation of breast cancer cells by a p21-activated kinase-dependent pathway

Jean-Paul Mira, Valerie Benard, John Groffen, Luraynne C. Sanders, Ulla G. Knaus

Proc Natl Acad Sci U S A. 2000 Jan 4; 97(1): 185–189. doi: 10.1073/pnas.97.1.185

PMCID:: PMC26637

Article PDF–251K

Select item 14107646.

Rac1 and Rac3 isoform activation is involved in the invasive and metastatic phenotype of human breast cancer cells

Paige J Baugher, Lakshmi Krishnamoorthy, Janet E Price, Surangani F Dharmawardhane

Breast Cancer Res. 2005; 7(6): R965–R974. Published online 2005 Sep 30. doi: 10.1186/bcr1329

PMCID:: PMC1410764

Article PDF–611K

Select item 86992927.

Pathophysiological Mechanisms in Neurodevelopmental Disorders Caused by Rac GTPases Dysregulation: What’s behind Neuro-RACopathies

Marcello Scala, Masashi Nishikawa, Koh-ichi Nagata, Pasquale Striano

Cells. 2021 Dec; 10(12): 3395. Published online 2021 Dec 2. doi: 10.3390/cells10123395

PMCID:: PMC8699292

Article PDF–1.8M

Select item 57162848.

Rac3 regulates breast cancer invasion and metastasis by controlling adhesion and matrix degradation

Sara K. Donnelly, Ramon Cabrera, Serena P.H. Mao, John R. Christin, Bin Wu, Wenjun Guo, Jose Javier Bravo-Cordero, John S. Condeelis, Jeffrey E. Segall, Louis Hodgson

J Cell Biol. 2017 Dec 4; 216(12): 4331–4349. doi: 10.1083/jcb.201704048

PMCID:: PMC5716284

Article PDF–2.7M

Select item 35389529.

The nuclear cofactor RAC3/AIB1/SRC-3 enhances Nrf2 signaling by interacting with transactivation domains

Jung-Hwan Kim, Siwang Yu, J. Don Chen, A.-N. Tony Kong

Oncogene. Author manuscript; available in PMC 2013 Jul 24.

Published in final edited form as: Oncogene. 2013 Jan 24; 32(4): 514–527. Published online 2012 Feb 27. doi: 10.1038/onc.2012.59

PMCID:: PMC3538952

Article PDF–1.9M

Select item 303152710.

The Actin Binding Domain of βI-Spectrin Regulates the Morphological and Functional Dynamics of Dendritic Spines

Michael W. Nestor, Xiang Cai, Michele R. Stone, Robert J. Bloch, Scott M. Thompson

PLoS One. 2011; 6(1): e16197. Published online 2011 Jan 31. doi: 10.1371/journal.pone.0016197

PMCID:: PMC3031527

Article PDF–995K

Select item 399421611.

F-box protein complex FBXL19 regulates TGFβ1-induced E-cadherin down-regulation by mediating Rac3 ubiquitination and degradation

Su Dong, Jing Zhao, Jianxin Wei, Rachel K Bowser, Andrew Khoo, Zhonghui Liu, James D Luketich, Arjun Pennathur, Haichun Ma, Yutong Zhao

Mol Cancer. 2014; 13: 76. Published online 2014 Apr 1. doi: 10.1186/1476-4598-13-76

PMCID:: PMC3994216

Article PDF–2.4M

Select item 373350312.

Matrix Metalloproteinase Induction of Rac1b, a Key Effector of Lung Cancer Progression

Melody L. Stallings-Mann, Jens Waldmann, Ying Zhang, Erin Miller, Mona L. Gauthier, Daniel W. Visscher, Gregory P. Downey, Evette S. Radisky, Alan P. Fields, Derek C. Radisky

Sci Transl Med. Author manuscript; available in PMC 2013 Aug 5.

Published in final edited form as: Sci Transl Med. 2012 Jul 11; 4(142): 142ra95. doi: 10.1126/scitranslmed.3004062

PMCID:: PMC3733503

Article PDF–5.9M

Select item 346952313.

Matrix compliance regulates Rac1b localization, NADPH oxidase assembly, and epithelial–mesenchymal transition

KangAe Lee, Qike K. Chen, Cecillia Lui, Magdalena A. Cichon, Derek C. Radisky, Celeste M. Nelson

Mol Biol Cell. 2012 Oct 15; 23(20): 4097–4108. doi: 10.1091/mbc.E12-02-0166

PMCID:: PMC3469523

Article PDF–4.1M

Select item 144607414.

Rac3-induced Neuritogenesis Requires Binding to Neurabin I

Donata Orioli, Ivan N. Colaluca, Miria Stefanini, Silvano Riva, Carlos G. Dotti, Fiorenzo A. Peverali

Mol Biol Cell. 2006 May; 17(5): 2391–2400. doi: 10.1091/mbc.E05-08-0753

PMCID:: PMC1446074

Article PDF–418K

Select item 577738315.

WNT Signaling Perturbations Underlie the Genetic Heterogeneity of Robinow Syndrome

Janson J. White, Juliana F. Mazzeu, Zeynep Coban-Akdemir, Yavuz Bayram, Vahid Bahrambeigi, Alexander Hoischen, Bregje W.M. van Bon, Alper Gezdirici, Elif Yilmaz Gulec, Francis Ramond, Renaud Touraine, Julien Thevenon, Marwan Shinawi, Erin Beaver, Jennifer Heeley, Julie Hoover-Fong, Ceren D. Durmaz, Halil Gurhan Karabulut, Ebru Marzioglu-Ozdemir, Atilla Cayir, Mehmet B. Duz, Mehmet Seven, Susan Price, Barbara Merfort Ferreira, Angela M. Vianna-Morgante, Sian Ellard, Andrew Parrish, Karen Stals, Josue Flores-Daboub, Shalini N. Jhangiani, Richard A. Gibbs, Baylor-Hopkins Center for Mendelian Genomics, Han G. Brunner, V. Reid Sutton, James R. Lupski, Claudia M.B. Carvalho

Am J Hum Genet. 2018 Jan 4; 102(1): 27–43. Published online 2017 Dec 21. doi: 10.1016/j.ajhg.2017.10.002