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Select item 110673471.

Interplay of RAP2 GTPase and the cytoskeleton in Hippo pathway regulation

Chenzhou Wu, Xiaomin Cai, Ying Wang, Carlos D. Rodriguez, Giorgia Zoaldi, Lydia Herrmann, Chun-Yuh Huang, Xiaoqiong Wang, Viraj R. Sanghvi, Rongze O. Lu, Zhipeng Meng

J Biol Chem. 2024 May; 300(5): 107257. Published online 2024 Apr 2. doi: 10.1016/j.jbc.2024.107257

PMCID:: PMC11067347

Abstract Article PDF–4.4M

Select item 60005072.

Rap2a真核表达质粒的鉴定及其对肺癌细胞迁移能力的影响

吴金霞, 桑苗苗, 曹文嘉, 郑骏年, 裴冬生

Zhongguo Fei Ai Za Zhi. 2014 Sep 20; 17(9): 643–648. Chinese. doi: 10.3779/j.issn.1009-3419.2014.09.01

Correction in:: Zhongguo Fei Ai Za Zhi. 2021 Mar 20; 24(3): 172.

PMCID:: PMC6000507

Abstract Article PDF–1.8M

Select item 55293683.

Rap2a serves as a potential prognostic indicator of renal cell carcinoma and promotes its migration and invasion through up-regulating p-Akt

Jin-Xia Wu, Wen-Qi Du, Xiu-Cun Wang, Lu-Lu Wei, Fu-Chun Huo, Yao-Jie Pan, Xiao-Jin Wu, Dong-Sheng Pei

Sci Rep. 2017; 7: 6623. Published online 2017 Jul 26. doi: 10.1038/s41598-017-06162-7

Correction in:: Sci Rep. 2021; 11: 14878.

PMCID:: PMC5529368

Abstract Article PDF–2.2M

Select item 26651304.

Constitutively Active Rap2 Transgenic Mice Display Fewer Dendritic Spines, Reduced Extracellular Signal-Regulated Kinase Signaling, Enhanced Long-Term Depression, and Impaired Spatial Learning and Fear Extinction

Jubin Ryu, Kensuke Futai, Monica Feliu, Richard Weinberg, Morgan Sheng

J Neurosci. 2008 Aug 13; 28(33): 8178–8188. doi: 10.1523/JNEUROSCI.1944-08.2008

PMCID:: PMC2665130

Abstract Article PDF–5.2M

Select item 98280325.

TGF-β1-induced RAP2 regulates invasion in pancreatic cancer: RAP2 regulates invasion in pancreatic cancer

Kaizhou Jin, Chen Liu, He Cheng, Qinglin Fei, Qiuyi Huang, Zhiwen Xiao, Xianjun Yu, Weiding Wu

Acta Biochim Biophys Sin (Shanghai) 2022 Mar; 54(3): 361–369. Published online 2022 Feb 25. doi: 10.3724/abbs.2022015

PMCID:: PMC9828032

Abstract Article PDF–6.5M

Select item 87760816.

Simulated Microgravity Increases the Permeability of HUVEC Monolayer through Up-Regulation of Rap1GAP and Decreased Rap2 Activation

Shuliang Shi, Jing Li, Erzhuo Li, Wenqi Guo, Yao He, Jinpeng Wang, Yao Zhang, Lei Yue, Lijun Wei

Int J Mol Sci. 2022 Jan; 23(2): 630. Published online 2022 Jan 6. doi: 10.3390/ijms23020630

PMCID:: PMC8776081

Abstract Article PDF–4.4M

Select item 81800207.

Tumor suppressive role of miR-33a-5p in pancreatic ductal adenocarcinoma cells by directly targeting RAP2A

Yanfen Lian, Dongxiao Jiang, Jiangtao Sun

Cell Mol Biol Lett. 2021; 26: 24. Published online 2021 Jun 5. doi: 10.1186/s11658-021-00265-w

PMCID:: PMC8180020

Abstract Article PDF–5.4M

Select item 61286988.

RAP2 Mediates Mechano-responses of Hippo Pathway

Zhipeng Meng, Yunjiang Qiu, Kimberly C. Lin, Aditya Kumar, Jesse K. Placone, Cao Fang, Kuei-Chun Wang, Shicong Lu, Margaret Pan, Audrey W. Hong, Toshiro Moroishi, Min Luo, Steven W. Plouffe, Yarui Diao, Zhen Ye, Hyun Woo Park, Xiaoqiong Wang, Fa-Xing Yu, Shu Chien, Cun-Yu Wang, Bing Ren, Adam J. Engler, Kun-Liang Guan

Nature. Author manuscript; available in PMC 2019 Feb 22.

Published in final edited form as: Nature. 2018 Aug; 560(7720): 655–660. Published online 2018 Aug 22. doi: 10.1038/s41586-018-0444-0

PMCID:: PMC6128698

Abstract Article PDF–5.7M

Select item 51664359.

β-Arrestin 1-dependent regulation of Rap2 is required for fMLP-stimulated chemotaxis in neutrophil-like HL-60 cells

Nidhi Gera, Kenneth D. Swanson, Tian Jin

J Leukoc Biol. 2017 Jan; 101(1): 239–251. Published online 2016 Aug 4. doi: 10.1189/jlb.2A1215-572R

PMCID:: PMC5166435

Abstract Article

Select item 461906010.

Genome-Wide Association Study of Peripheral Arterial Disease in a Japanese Population

Mitsuru Matsukura, Kouichi Ozaki, Atsushi Takahashi, Yoshihiro Onouchi, Takashi Morizono, Hiroyoshi Komai, Hiroshi Shigematsu, Toshifumi Kudo, Yoshinori Inoue, Hideo Kimura, Akihiro Hosaka, Kunihiro Shigematsu, Teturo Miyata, Toshiaki Watanabe, Tatsuhiko Tsunoda, Michiaki Kubo, Toshihiro Tanaka

PLoS One. 2015; 10(10): e0139262. Published online 2015 Oct 21. doi: 10.1371/journal.pone.0139262

PMCID:: PMC4619060

Abstract Article PDF–868K

Select item 138602911.

Biochemical characterization of RGS14: RGS14 activity towards G-protein α subunits is independent of its binding to Rap2A

Vivek Mittal, Maurine E. Linder

Biochem J. 2006 Feb 15; 394(Pt 1): 309–315. Prepublished online 2005 Oct 25. Published online 2006 Jan 27. doi: 10.1042/BJ20051086

PMCID:: PMC1386029

Abstract Article PDF–222K

Select item 117019012.

Crystal structures of the small G protein Rap2A in complex with its substrate GTP, with GDP and with GTPgammaS.

J Cherfils, J Ménétrey, G Le Bras, I Janoueix-Lerosey, J de Gunzburg, J R Garel, I Auzat

EMBO J. 1997 Sep 15; 16(18): 5582–5591. doi: 10.1093/emboj/16.18.5582

PMCID:: PMC1170190

Summary PDF–734K

Select item 113217413.

Prenyl group identification of rap2 proteins: a ras superfamily member other than ras that is farnesylated.

F X Farrell, K Yamamoto, E G Lapetina

Biochem J. 1993 Jan 15; 289(Pt 2): 349–355. doi: 10.1042/bj2890349

PMCID:: PMC1132174

Summary Page Browse PDF–1.4M

Select item 775149014.

lncRNA FLVCR1-AS1 drives colorectal cancer progression via modulation of the miR-381/RAP2A axis

Yi Han, Xiaoyan Wang, Enqiang Mao, Boyong Shen, Liang Huang

Mol Med Rep. 2021 Feb; 23(2): 139. Published online 2020 Dec 13. doi: 10.3892/mmr.2020.11778

PMCID:: PMC7751490

Abstract Article PDF–9.9M

Select item 585484915.

Disrupting CD147-RAP2 interaction abrogates erythrocyte invasion by Plasmodium falciparum

Meng-Yao Zhang, Yang Zhang, Xiao-Dong Wu, Kun Zhang, Peng Lin, Hui-Jie Bian, Min-Min Qin, Wan Huang, Ding Wei, Zhao Zhang, Jiao Wu, Ruo Chen, Fei Feng, Bin Wang, Gang Nan, Ping Zhu, Zhi-Nan Chen

Blood. 2018 Mar 8; 131(10): 1111–1121. Prepublished online 2018 Jan 19. doi: 10.1182/blood-2017-08-802918

PMCID:: PMC5854849

Abstract Article

Select item 358528216.

Rap1 and Rap2 Antagonistically Control Endothelial Barrier Resistance

Willem-Jan Pannekoek, Jelena R. Linnemann, Patricia M. Brouwer, Johannes L. Bos, Holger Rehmann

PLoS One. 2013; 8(2): e57903. Published online 2013 Feb 28. doi: 10.1371/journal.pone.0057903

PMCID:: PMC3585282

Abstract Article PDF–722K

Select item 789427417.

Phosphorylation of Synaptic GTPase-activating Protein (synGAP) by Polo-Like Kinase (Plk2) alters the Ratio of Its GAP Activity toward HRas, Rap1 and Rap2 GTPases

Ward G. Walkup, 4th, Michael J. Sweredoski, Robert L. Graham, Sonja Hess, Mary B. Kennedy

Biochem Biophys Res Commun. Author manuscript; available in PMC 2021 Feb 19.

Published in final edited form as: Biochem Biophys Res Commun. 2018 Sep 10; 503(3): 1599–1604. Published online 2018 Jul 24. doi: 10.1016/j.bbrc.2018.07.087